Výsledky vyhledávání - "Protein folding"

Resource-efficient quantum algorithm for protein folding Autor Robert, Anton, Barkoutsos, Panagiotis Kl, Woerner, Stefan, Tavernelli, Ivano

“…Predicting the three-dimensional structure of a protein from its primary sequence of amino acids is known as the protein folding problem…”
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Protein folding and modification in the mammalian endoplasmic reticulum Autor Braakman, Ineke, Bulleid, Neil J

“…Analysis of the human genome reveals that approximately a third of all open reading frames code for proteins that enter the endoplasmic reticulum (ER),…”
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Modern Kinetics and Mechanism of Protein Folding: A Retrospective Autor Eaton, William A

“…Modern experimental kinetics of protein folding began in the early 1990s with the introduction of nanosecond laser pulses to trigger the folding reaction, providing an almost 10 -fold improvement…”
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Comprehensive folding variations for protein folding Autor Yang, Jiaan, Cheng, Wen Xiang, Zhao, Xiao Fei, Wu, Gang, Sheng, Shi Tong, Hu, Qiyue, Ge, Hu, Qin, Qianshan, Jin, Xinshen, Zhang, Lianshan, Zhang, Peng

“…The revelation of protein folding is a challenging subject in both discovery and description…”
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Globular Protein Folding In Vitro and In Vivo Autor Gruebele, Martin, Dave, Kapil, Sukenik, Shahar

“…In vitro, computational, and theoretical studies of protein folding have converged to paint a rich and complex energy landscape…”
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Beyond protein folding: The pleiotropic functions of PPIases in cellular processes and microbial virulence Autor Rakshit, Roopshali, Bahl, Aayush, Arunima, Arunima, Pandey, Saurabh, Tripathi, Deeksha

“…Peptidyl prolyl cis/trans isomerases (PPIases), a ubiquitously distributed superfamily of enzymes, associated with signal transduction, trafficking, assembly,…”
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Frontiers in Protein Folding and Related Areas – in Memory of Professor Sir Christopher M. Dobson (1949–2019)

“…), who made outstanding contributions to the advancement of studies on protein folding and its related areas and played an irreplaceable role in the promotion of protein science…”
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Physics of Protein Folding, Misfolding, and Intrinsic Disorder: A Themed Issue in Honour of Professor Vladimir Uversky on the Occasion of His 60th Birthday

“…This Special Issue of Biomolecules, “Physics of Protein Folding, Misfolding, and Intrinsic Disorder…”
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The how’s and why’s of protein folding intermediates Autor Tsytlonok, Maksym, Itzhaki, Laura S.

“… The nature and role of intermediates have been the subject of much heated debate in the field of protein folding…”
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Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli Autor Wiebelhaus, Nancy, Zaengle-Barone, Jacqueline M, Hwang, Kevin K, Franz, Katherine J, Fitzgerald, Michael C

“…, thereby providing new insight into ionophore-induced copper toxicity in . The protein folding stability analysis employed a one-pot protocol for ulse roteolysis (PP…”
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Protein Folding Modulation in Cells Subject to Differentiation and Stress Autor Gnutt, David, Sistemich, Linda, Ebbinghaus, Simon

“…Cytomimetic media are used to mimic the physicochemical properties of the cellular milieu in an experiment. The motivation is that compared to entire cells,…”
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Oxidative Protein Folding Promotion by Imidazoyl-conjugated Thiol Autor Okada, Shunsuke, Matsumoto, Yosuke, Okumura, Masaki, Muraoka, Takahiro

“…The promotion of protein folding is an important subject that can contribute to the efficient production of biological medicines…”
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Protein folding and surface interaction phase diagrams in vitro and in cells Autor Gruebele, Martin

“… This review discusses three aspects of protein phase diagrams: first, the relevance of phase diagrams to protein folding and function in vitro and in cells…”
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Evaluating the Effects of Cutoffs and Treatment of Long-range Electrostatics in Protein Folding Simulations Autor Piana, Stefano, Lindorff-Larsen, Kresten, Dirks, Robert M., Salmon, John K., Dror, Ron O., Shaw, David E.

“… that has been the subject of a number of previous protein folding studies--the villin headpiece…”
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Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway Autor Xu, Chengchao, Wang, Songyu, Thibault, Guillaume, Ng, Davis T W

“…Newly synthesized polypeptides fold and assemble with assistance from protein chaperones. Full maturation can take multiple attempts, exchanging chaperones at…”
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Emergence of glass-like behavior in Markov state models of protein folding dynamics Autor Weber, Jeffrey K, Jack, Robert L, Pande, Vijay S

“… Here, we address the subject with an application of space-time perturbation theory to the dynamics of protein folding Markov state models…”
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Real-time protein NMR spectroscopy and investigation of assisted protein folding Autor Kumar, Amit, Balbach, Jochen

“…During protein-folding reactions toward the native structure, short-lived intermediate states can be populated…”
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Periodic and stochastic thermal modulation of protein folding kinetics Autor Platkov, Max, Gruebele, Martin

“… Here we show that the two ideas can be combined to measure protein folding kinetics, either by periodic thermal modulation, or by creating artificial thermal noise that greatly exceeds natural thermal fluctuations…”
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Chaperonin-mediated protein folding: using a central cavity to kinetically assist polypeptide chain folding Autor Horwich, Arthur L., Fenton, Wayne A.

“…The chaperonin ring assembly GroEL provides kinetic assistance to protein folding in the cell by binding non-native protein in the hydrophobic central cavity of an open ring and subsequently, upon…”
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ER chaperone–metal interactions: Links to protein folding disorders Autor Tiffany-Castiglioni, Evelyn, Qian, Yongchang

“… Chaperone deficiencies in either amount or function are implicated in the etiology or pathogenesis of Alzheimer's disease and other protein folding disorders of the central nervous system…”
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