Search Results - "Protein Array Analysis/methods"

Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress by Biasutto, Lucia, Chiechi, Antonella, Couch, Robin, Liotta, Lance A., Espina, Virginia

“…Age-related macular degeneration (AMD) is a leading cause of vision loss and blindness among the elderly population in the industrialized world. One of the…”
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Self-Assembled Peptide Nanoarrays: An Approach to Studying Protein-Protein Interactions by Williams, Berea A. R., Lund, Kyle, Liu, Yan, Yan, Hao, Chaput, John C.

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Randomly oriented ZnO nanorods as advanced substrate for high-performance protein microarrays by Hu, Weihua, Liu, Yingshuai, Zhu, Zhihong, Yang, Hongbin, Li, Chang Ming

“…When aligned or patterned nanostructures attract great interest, the randomly arranged nanostructures are often ignored. A nanostructure with randomly oriented…”
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Erkitinib, a novel EGFR tyrosine kinase inhibitor screened using a ProteoChip system from a phytochemical library by Kim, Eung-Yoon, Choi, Young-Jin, Park, Chan-Won, Kang, In-Cheol

“…Receptor tyrosine kinases (PTKs) play key roles in the pathogenesis of numerous human diseases, including cancer. Therefore PTK inhibitors are currently under…”
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Nanosystems for biosensing: multianalyte immunoassay on a protein chip by Tamiya, Eiichi, Zhi, Zheng-Liang, Morita, Yasutaka, Hasan, Quamrul

“…This chapter describes the construction of addressable two-dimensional (2D) microarrays via the random fluidic self-assembly of metallic particles and the use…”
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Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (Reverse Phase Protein Array) society by Akbani, Rehan, Becker, Karl-Friedrich, Carragher, Neil, Goldstein, Ted, de Koning, Leanne, Korf, Ulrike, Liotta, Lance, Mills, Gordon B, Nishizuka, Satoshi S, Pawlak, Michael, Petricoin, 3rd, Emanuel F, Pollard, Harvey B, Serrels, Bryan, Zhu, Jingchun

“…Reverse phase protein array (RPPA) technology introduced a miniaturized "antigen-down" or "dot-blot" immunoassay suitable for quantifying the relative,…”
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Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays by Li, Jun, Zhao, Wei, Akbani, Rehan, Liu, Wenbin, Ju, Zhenlin, Ling, Shiyun, Vellano, Christopher P, Roebuck, Paul, Yu, Qinghua, Eterovic, A Karina, Byers, Lauren A, Davies, Michael A, Deng, Wanleng, Gopal, Y N Vashisht, Chen, Guo, von Euw, Erika M, Slamon, Dennis, Conklin, Dylan, Heymach, John V, Gazdar, Adi F, Minna, John D, Myers, Jeffrey N, Lu, Yiling, Mills, Gordon B, Liang, Han

“…Cancer cell lines are major model systems for mechanistic investigation and drug development. However, protein expression data linked to high-quality DNA, RNA,…”
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SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses by Jiang, He-wei, Li, Yang, Zhang, Hai-nan, Wang, Wei, Yang, Xiao, Qi, Huan, Li, Hua, Men, Dong, Zhou, Jie, Tao, Sheng-ce

“…We still know very little about how the human immune system responds to SARS-CoV-2. Here we construct a SARS-CoV-2 proteome microarray containing 18 out of the…”
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In-situ ultra-sensitive infrared absorption spectroscopy of biomolecule interactions in real time with plasmonic nanoantennas by Adato, Ronen, Altug, Hatice

“…Infrared absorption spectroscopy is a powerful biochemical analysis tool as it extracts detailed molecular structural information in a label-free fashion. Its…”
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Highly multiplexed simultaneous detection of RNAs and proteins in single cells by Frei, Andreas P, Bava, Felice-Alessio, Zunder, Eli R, Hsieh, Elena W Y, Chen, Shih-Yu, Nolan, Garry P, Gherardini, Pier Federico

“…PLAYR (proximity ligation assay for RNA) enables highly multiplexed transcript quantification in combination with protein marker detection in single cells…”
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Developments and Applications of Functional Protein Microarrays by Syu, Guan-Da, Dunn, Jessica, Zhu, Heng

“…Protein microarrays are crucial tools in the study of proteins in an unbiased, high-throughput manner, as they allow for characterization of up to thousands of…”
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Nanobodies and recombinant binders in cell biology by Helma, Jonas, Cardoso, M Cristina, Muyldermans, Serge, Leonhardt, Heinrich

“…Antibodies are key reagents to investigate cellular processes. The development of recombinant antibodies and binders derived from natural protein scaffolds has…”
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A human lectin array for characterizing host-pathogen interactions by Benjamin, Stefi V., Jégouzo, Sabine A.F., Lieng, Chloe, Daniels, Connor, Coispeau, Marine, Lau, Rikin J., Kim, Suyeon, Metaxa, Yasmine, Philpott, James, Li, Tiannuo, Dai, Chao, Wang, Xin, Newby, Maddy L., Pier, Gerald B., Crispin, Max, Clements, Abigail, Taylor, Maureen E., Drickamer, Kurt

“…A human lectin array has been developed to probe the interactions of innate immune receptors with pathogenic and commensal microorganisms. Following the…”
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Proteome-wide microarray-based screening of PAR-binding proteins by Kang, Bong Gu, Kang, Sung-Ung, Jin Kim, Jae, Kwon, Ji-Sun, Gagné, Jean-Philippe, Yun Lee, Seo, Kim, Soyeon, Lee, Karl S, Ha, Shinwon, Seop Jeong, Jun, Lee, Yun-Il, Zhu, Heng, Kim, Dongsan, Poirier, Guy G, Chul Kang, Ho, Dawson, Valina L, Dawson, Ted M

“…Abstract Poly (ADP-ribose) (PAR) plays a crucial role in intracellular signaling and scaffolding through covalent modification or non-covalent binding to…”
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An Interactive Database for the Assessment of Histone Antibody Specificity by Rothbart, Scott B, Dickson, Bradley M, Raab, Jesse R, Grzybowski, Adrian T, Krajewski, Krzysztof, Guo, Angela H, Shanle, Erin K, Josefowicz, Steven Z, Fuchs, Stephen M, Allis, C David, Magnuson, Terry R, Ruthenburg, Alexander J, Strahl, Brian D

“…Access to high-quality antibodies is a necessity for the study of histones and their posttranslational modifications (PTMs). Here we debut the Histone Antibody…”
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Direct Profiling of Extracellular Vesicle Surface Markers in Plasma: A Proof-of-Concept Study by Clegg, Lee-Ann, Jensen, Rebecca Best, Bæk, Rikke, Mumm, Birgitte Hviid, Sørensen, Maria Kjølhede, Blauenfeldt, Rolf Ankerlund, Drasbek, Kim Ryun, Jørgensen, Malene Møller

“…During the last decade, non-invasive methods such as liquid biopsy have increasingly replaced invasive techniques for diagnosing and monitoring diseases…”
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Disease-specific molecular events in cortical multiple sclerosis lesions by Fischer, Marie Therese, Wimmer, Isabella, Höftberger, Romana, Gerlach, Susanna, Haider, Lukas, Zrzavy, Tobias, Hametner, Simon, Mahad, Don, Binder, Christoph J, Krumbholz, Markus, Bauer, Jan, Bradl, Monika, Lassmann, Hans

“…Cortical lesions constitute an important part of multiple sclerosis pathology. Although inflammation appears to play a role in their formation, the mechanisms…”
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Multiplexed sandwich immunoassays using electrochemiluminescence imaging resolved at the single bead level by Deiss, Frédérique, LaFratta, Christopher N, Symer, Matthew, Blicharz, Timothy M, Sojic, Neso, Walt, David R

“…A new class of bead-based microarray that uses electrogenerated chemiluminescence (ECL) as a readout mechanism to detect multiple antigens simultaneously is…”
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Label-Free Quantitative Detection of Tumor-Derived Exosomes through Surface Plasmon Resonance Imaging by Zhu, Ling, Wang, Kun, Cui, Jian, Liu, Huan, Bu, Xiangli, Ma, Huailei, Wang, Weizhi, Gong, He, Lausted, Christopher, Hood, Leroy, Yang, Guang, Hu, Zhiyuan

“…Exosomes are endosome-derived membrane vesicles carrying proteins and nucleic acids that are involved in cellular functions such as intercellular…”
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Immobilization of Protein Macromolecules in Biochip Cells Made of Various Polymers by Shtylev, G F, Shishkin, I Yu, Vasiliskov, V A, Barsky, V E, Kuznetsova, V E, Shershov, V E, Polyakov, S A, Miftakhov, R A, Butvilovskaya, V I, Zasedateleva, O A, Chudinov, A V

“…Microarrays with immobilized protein probes are used to analyze protein samples. Selection of materials for biochip fabrication, functionalization of the…”
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