Výsledky vyhľadávania - "Protein & cell"

Naringenin reduces lung metastasis in a breast cancer resection model Autor Qin, Lei, Jin, Lingtao, Lu, Linlin, Lu, Xiaoyan, Zhang, Chunling, Zhang, Fayun, Liang, Wei

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Gadd45a deletion aggravates hematopoietic stem cell dysfunction in ATM-deficient mice Autor Chen, Yulin, Yang, Runan, Guo, Peng, Ju, Zhenyu

“…Ataxia telangiectasia mutated （ATM） kinase plays an essential role in the maintenance of genomic stability. ATM-deficient （ATM-/-） mice exhibit…”
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Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy Autor Koppula, Pranavi, Zhuang, Li, Gan, Boyi

“…The cystine/glutamate antiporter SLC7A11 (also commonly known as xCT) functions to import cystine for glutat hione biosynthesis and antioxidant defense and is…”
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Metabolic reprogramming and epigenetic modifications on the path to cancer Autor Sun, Linchong, Zhang, Huafeng, Gao, Ping

“…Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally regulate each other, are among the well-known cancer hallmarks. Recent…”
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A practical guide to amplicon and metagenomic analysis of microbiome data Autor Liu, Yong-Xin, Qin, Yuan, Chen, Tong, Lu, Meiping, Qian, Xubo, Guo, Xiaoxuan, Bai, Yang

“…Advances in high-throughput sequencing (HTS) have fostered rapid developments in the field of microbiome research, and massive microbiome datasets are now…”
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Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids Autor Zhao, Bing, Ni, Chao, Gao, Ran, Wang, Yuyan, Yang, Li, Wei, Jinsong, Lv, Ting, Liang, Jianqing, Zhang, Qisheng, Xu, Wei, Xie, Youhua, Wang, Xiaoyue, Yuan, Zhenghong, Liang, Junbo, Zhang, Rong, Lin, Xinhua

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Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332 Autor Zhao, Yao, Fang, Chao, Zhang, Qi, Zhang, Ruxue, Zhao, Xiangbo, Duan, Yinkai, Wang, Haofeng, Zhu, Yan, Feng, Lu, Zhao, Jinyi, Shao, Maolin, Yang, Xiuna, Zhang, Leike, Peng, Chao, Yang, Kailin, Ma, Dawei, Rao, Zihe, Yang, Haitao

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Ferroptosis, radiotherapy, and combination therapeutic strategies Autor Lei, Guang, Mao, Chao, Yan, Yuelong, Zhuang, Li, Gan, Boyi

“…Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages of polyunsaturated-fatty-acid-containing phospholipids in cellular…”
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The role of the gut microbiome and its metabolites in metabolic diseases Autor Wu, Jiayu, Wang, Kai, Wang, Xuemei, Pang, Yanli, Jiang, Changtao

“…It is well known that an unhealthy lifestyle is a major risk factor for metabolic diseases, while in recent years, accumulating evidence has demonstrated that…”
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The microbiota-gut-brain axis and neurodevelopmental disorders Autor Wang, Qinwen, Yang, Qianyue, Liu, Xingyin

“…The gut microbiota has been found to interact with the brain through the microbiota-gut-brain axis, regulating various physiological processes. In recent…”
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Effect of pH, temperature and freezing-thawing on quantity changes and cellular uptake of exosomes Autor Cheng, Yirui, Zeng, Qingyu, Han, Qing, X ia, Weiliang

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Mapping the epigenetic modifications of DNA and RNA Autor Zhao, Lin-Yong, Song, Jinghui, Liu, Yibin, Song, Chun-Xiao, Yi, Chengqi

“…Over 17 and 160 types of chemical modifications have been identified in DNA and RNA, respectively. The interest in understanding the various biological…”
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Oral microbiomes: more and more importance in oral cavity and whole body Autor Gao, Lu, Xu, Tiansong, Huang, Gang, Jiang, Song, Gu, Yan, Chen, Feng

“…Microbes appear in every corner of human life, and microbes affect every aspect of human life. The human oral cavity contains a number of different habitats…”
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Targeting the alternative bile acid synthetic pathway for metabolic diseases Autor Jia, Wei, Wei, Meilin, Rajani, Cynthia, Zheng, Xiaojiao

“…The gut microbiota is profoundly involved in glucose and lipid metabolism, in part by regulating bile acid (BA) metabolism and affecting multiple BA-receptor…”
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Unexpected guests in the tumor microenvironment: microbiome in cancer Autor Wong-Rolle, Abigail, Wei, Haohan Karen, Zhao, Chen, Jin, Chengcheng

“…Although intestinal microbiome have been established as an important biomarker and regulator of cancer development and therapeutic response, less is known…”
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Alzheimer's disease: insights into pathology, molecular mechanisms, and therapy Autor Zheng, Qiuyang, Wang, Xin

“…Alzheimer's disease (AD), the leading cause of dementia, is characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain. This…”
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Antibody-drug conjugates: recent advances in conjugation and linker chemistries Autor Tsuchikama, Kyoji, An, Zhiqiang

“…The antibody-drug conjugate (ADC), a humanized or human monoclonal antibody conjugated with highly cytotoxic small molecules (payloads) through chemical…”
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The hierarchy quorum sensing network in Pseudomonas aeruginosa Autor Lee, Jasmine, Zhang, Lianhui

“…Pseudomonas aeruginosa causes severe and persistent infections in immune compromised individuals and cystic fibrosis sufferers. The infection is hard to…”
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The microbiome in inflammatory bowel diseases: from pathogenesis to therapy Autor Liu, Sheng, Zhao, Wenjing, Lan, Ping, Mou, Xiangyu

“…Inflammatory bowel disease (IBD) has become a global disease with accelerating incidence worldwide in the 21st century while its accurate etiology remains…”
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Memory T cells: strategies for optimizing tumor immunotherapy Autor Liu, Qingjun, Sun, Zhongjie, Chen, Ligong

“…Several studies have demonstrated that memory T cells including stem cell memory (Tscm) T cells and central memory (Tcm) T cells show superior persistence and…”
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