Search Results - "Prados Carrasco, Ferran"

Investigating colour vision and its structural correlates 15 years following a first demyelinating event by Yam, Charmaine, Brownlee, Wallace J, Prados Carrasco, Ferran, Toosy, Ahmed, Ciccarelli, Olga

“…BackgroundWe investigated the long-term colour and contrast vision outcomes, 15 years after a first demyelinating event, with their structural correlates using…”
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Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial by Chataway, Jeremy, De Angelis, Floriana, Connick, Peter, Parker, Richard A, Plantone, Domenico, Doshi, Anisha, John, Nevin, Stutters, Jonathan, MacManus, David, Prados Carrasco, Ferran, Barkhof, Frederik, Ourselin, Sebastien, Braisher, Marie, Ross, Moira, Cranswick, Gina, Pavitt, Sue H, Giovannoni, Gavin, Gandini Wheeler-Kingshott, Claudia Angela, Hawkins, Clive, Sharrack, Basil, Bastow, Roger, Weir, Christopher J, Stallard, Nigel, Chandran, Siddharthan, Chataway, Jeremy, Gandini Wheeler-Kingshott, Claudia A.M., De Angelis, Floriana, Plantone, Domenico, Doshi, Anisha, John, Nevin, Williams, Thomas, Braisher, Marie, Beyene, Tiggy, Bassan, Vanessa, Zapata, Alvin, Chandran, Siddharthan, Connick, Peter, Lyle, Dawn, Cameron, James, Mollison, Daisy, Colville, Shuna, Dhillon, Baljean, Weir, Christopher J., Parker, Richard A., Ross, Moira, Cranswick, Gina, Giovannoni, Gavin, Gnanapavan, Sharmilee, Nicholas, Richard, Rashid, Waqar, Aram, Julia, Ford, Helen, Overell, James, Young, Carolyn, Arndt, Heinke, Duddy, Martin, Guadagno, Joe, Evangelou, Nikolaos, Craner, Matthew, Palace, Jacqueline, Hobart, Jeremy, Sharrack, Basil, Paling, David, Hawkins, Clive, Kalra, Seema, McLean, Brendan, Stallard, Nigel, Bastow, Roger

“…Neurodegeneration is the pathological substrate that causes major disability in secondary progressive multiple sclerosis. A synthesis of preclinical and…”
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Single-centre, prospective cohort to predict optimal individualised treatment response in multiple sclerosis (POINT-MS): a cohort profile by Christensen, Ronja, Cruciani, Alessandro, Al-Araji, Sarmad, Bianchi, Alessia, Chard, Declan, Fourali, Samih, Hamed, Weaam, Hammam, Ahmed, He, Anna, Kanber, Baris, Maccarrone, Davide, Moccia, Marcello, Mohamud, Suraya, Nistri, Riccardo, Passalis, Anestis, Pozzilli, Valeria, Prados Carrasco, Ferran, Samdanidou, Eirini, Song, Joy, Wingrove, Jed, Yam, Charmaine, Yiannakas, Marios, Thompson, Alan J, Toosy, Ahmed, Hacohen, Yael, Barkhof, Frederik, Ciccarelli, Olga, Aojula, Anuriti, Champas, Dimitrios, Collorone, Sara, Eshaghi, Arman, Goodkin, Olivia, Kurd, Mohammad, Panella, Elena, Pansari, Fatima, Stutters, Jonathan, Toorop, Alyssa, Zhang, Le, Brownlee, Wallace, Chataway, Jeremy, Chung, Karen, Angelis, Floriana De, Leary, Siobhan, Khaleeli, Zhaleh, Wright, Sarah, Swanton, Josephine, Trip, Anand, Gandini Wheeler-Kingshott, Claudia Angela, Solanky, Bhavana, Parker, Chloe, Stuart, Michaela, Haagenrud, Hanne, Wilson, Heather

“…PurposeMultiple sclerosis (MS) is a chronic neurological condition that affects approximately 150 000 people in the UK and presents a significant healthcare…”
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Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (MS-SMART): a multiarm phase IIb randomised, double-blind, placebo-controlled clinical trial comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis by Connick, Peter, De Angelis, Floriana, Parker, Richard A, Plantone, Domenico, Doshi, Anisha, John, Nevin, Stutters, Jonathan, MacManus, David, Prados Carrasco, Ferran, Barkhof, Frederik, Ourselin, Sebastien, Braisher, Marie, Ross, Moira, Cranswick, Gina, Pavitt, Sue H, Giovannoni, Gavin, Gandini Wheeler-Kingshott, Claudia Angela, Hawkins, Clive, Sharrack, Basil, Bastow, Roger, Weir, Christopher J, Stallard, Nigel, Chandran, Siddharthan, Chataway, Jeremy

“…IntroductionThe major unmet need in multiple sclerosis (MS) is for neuroprotective therapies that can slow (or ideally stop) the rate of disease progression…”
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Magnetisation transfer ratio abnormalities in primary and secondary progressive multiple sclerosis by Brown, James William L, Chowdhury, Azmain, Kanber, Baris, Prados Carrasco, Ferran, Eshaghi, Arman, Sudre, Carole H, Pardini, Matteo, Samson, Rebecca S, van de Pavert, Steven Hp, Wheeler-Kingshott, Claudia Gandini, Chard, Declan T

“…In relapse-onset multiple sclerosis (MS), tissue abnormality - as assessed with magnetisation transfer ratio (MTR) imaging - is greater in the outer cortical…”
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An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis by De Meo, Ermelinda, Prados Carrasco, Ferran, Brown, J. William L., Coles, Alasdair J., Cunniffe, Nick G., Jolly, Amy E., Kanber, Baris, Samson, Rebecca, Barkhof, Frederik, Chard, Declan

“…Objective To assess the pathological mechanisms contributing to white matter (WM) lesion expansion or contraction and remyelination in multiple sclerosis (MS)…”
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Qualitative and Quantitative Comparison of Hippocampal Volumetric Software Applications: Do All Roads Lead to Rome? by Mangesius, Stephanie, Haider, Lukas, Lenhart, Lukas, Steiger, Ruth, Prados Carrasco, Ferran, Scherfler, Christoph, Gizewski, Elke R.

“…Brain volumetric software is increasingly suggested for clinical routine. The present study quantifies the agreement across different software applications…”
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Brain reserve and physical disability in secondary progressive multiple sclerosis by John, Nevin, Li, Yingtong, De Angelis, Floriana, Stutters, Jonathan, Prados Carrasco, Ferran, Eshaghi, Arman, Doshi, Anisha, Calvi, Alberto, Williams, Thomas, Plantone, Domenico, Phan, Thanh, Barkhof, Frederik, Chataway, Jeremy, Ourselin, Sebastien, Braisher, Marie, Beyene, Tiggy, Bassan, Vanessa, Zapata, Alvin, Chandran, Siddharthan, Connick, Peter, Lyle, Dawn, Cameron, James, Mollison, Daisy, Colville, Shuna, Dhillon, Baljean, Ross, Moira, Cranswick, Gina, Walker, Allan, Smith, Lorraine, Giovannoni, Gavin, Gnanapavan, Sharmilee, Nicholas, Richard, Rashid, Waqar, Aram, Julia, Ford, Helen, Pavitt, Sue H, Overell, James, Young, Carolyn, Arndt, Heinke, Duddy, Martin, Guadagno, Joe, Evangelou, Nikolaos, Craner, Matthew, Palace, Jacqueline, Hobart, Jeremy, Sharrack, Basil, Paling, David, Hawkins, Clive, Kalra, Seema, McLean, Brendan, Stallard, Nigel, Bastow, Roger

“…BackgroundThe brain reserve hypothesis posits that larger maximal lifetime brain growth (MLBG) may confer protection against physical disability in multiple…”
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Artificial Intelligence and Multiple Sclerosis by Amin, Moein, Martínez-Heras, Eloy, Ontaneda, Daniel, Prados Carrasco, Ferran

“…In this paper, we analyse the different advances in artificial intelligence (AI) approaches in multiple sclerosis (MS). AI applications in MS range across…”
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Differentiating Multiple Sclerosis From AQP4-Neuromyelitis Optica Spectrum Disorder and MOG-Antibody Disease With Imaging by Cortese, Rosa, Prados Carrasco, Ferran, Tur, Carmen, Bianchi, Alessia, Brownlee, Wallace, De Angelis, Floriana, De La Paz, Isabel, Grussu, Francesco, Haider, Lukas, Jacob, Anu, Kanber, Baris, Magnollay, Lise, Nicholas, Richard S, Trip, Anand, Yiannakas, Marios, Toosy, Ahmed T, Hacohen, Yael, Barkhof, Frederik, Ciccarelli, Olga

“…Relapsing-remitting multiple sclerosis (RRMS), aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD), and myelin oligodendrocyte…”
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Slowly Expanding Lesions in Pediatric-Onset Multiple Sclerosis by Pozzilli, Valeria, Prados Carrasco, Ferran, Kim, Neena, Abdel-Mannan, Omar, Nistri, Riccardo, Goebl, Philipp, Hemingway, Cheryl, Biswas, Asthik, Mankad, Kshitij, Sudhakar, Sniya, Parida, Amitav, Wright, Sukhvir, Wassmer, Evangeline, Eyre, Michael, Lim, Ming, Rossor, Thomas, Eshaghi, Arman, Barkhof, Frederik, De Meo, Ermelinda, Ciccarelli, Olga, Hacohen, Yael

“…This cohort study examines the association between slowly expanding lesions and pediatric-onset multiple sclerosis among younger individuals, focusing on brain…”
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An abnormal periventricular magnetization transfer ratio gradient occurs early in multiple sclerosis by Brown, J William L, Pardini, Matteo, Brownlee, Wallace J, Fernando, Kryshani, Samson, Rebecca S, Prados Carrasco, Ferran, Ourselin, Sebastien, Gandini Wheeler-Kingshott, Claudia A M, Miller, David H, Chard, Declan T

“…In established multiple sclerosis, tissue abnormality-as assessed using magnetization transfer ratio-increases close to the lateral ventricles. We aimed to…”
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Improving the learning experience of business subjects in engineering studies using automatic spreadsheet correctors by Rafart Serra, Maria Assumpció, Bikfalvi, Andrea, Soler Masó, Josep, Prados Carrasco, Ferran, Poch Garcia, Jordi

“…The combination of two macro trends, ICT proliferation and novel approaches in education, has resulted in a series of opportunities with no precedent in terms…”
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Diffusivity anisotropy signature of the slowly expanding lesions predicts progression independent of relapse activity in multiple sclerosis by Calvi, Alberto, Vivó Pascual, Francesc, Solana, Elisabeth, Lopez-Soley, Elisabet, Kanber, Baris, Alba-Arbalat, Salut, Sepulveda, Maria, Martínez-Hernández, Eugenia, Cabrera-Maqueda, José Maria, Fonseca, Elianet, Medrano-Martorell, Santiago, Saiz, Albert, Blanco, Yolanda, Villoslada, Pablo, Prados Carrasco, Ferran, Martinez-Heras, Eloy, Llufriu, Sara

“…Slowly expanding lesions (SELs) in multiple sclerosis (MS) are markers of chronic active lesions and seem to trigger disability. This study aimed to analyse…”
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Segmenting the Inferior Alveolar Canal in CBCTs Volumes: The ToothFairy Challenge by Bolelli, Federico, Lumetti, Luca, Vinayahalingam, Shankeeth, Di Bartolomeo, Mattia, Pellacani, Arrigo, Marchesini, Kevin, van Nistelrooij, Niels, van Lierop, Pieter, Xi, Tong, Liu, Yusheng, Xin, Rui, Yang, Tao, Wang, Lisheng, Wang, Haoshen, Xu, Chenfan, Cui, Zhiming, Wodzinski, Marek, Muller, Henning, Kirchhoff, Yannick, Rokuss, Maximilian R., Maier-Hein, Klaus, Han, Jaehwan, Kim, Wan, Ahn, Hong-Gi, Szczepanski, Tomasz, Grzeszczyk, Michal K., Korzeniowski, Przemyslaw, Caselles-Ballester, Vicent, Paolo Burgos-Artizzu, Xavier, Prados Carrasco, Ferran, Berge', Stefaan, van Ginneken, Bram, Anesi, Alexandre, Grana, Costantino

“…In recent years, several algorithms have been developed for the segmentation of the Inferior Alveolar Canal (IAC) in Cone-Beam Computed Tomography (CBCT)…”
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Longitudinal Metabolite Changes in Progressive Multiple Sclerosis: A Study of 3 Potential Neuroprotective Treatments by John, Nevin A., Solanky, Bhavana S., De Angelis, Floriana, Parker, Richard A., Weir, Christopher J., Stutters, Jonathan, Carrasco, Ferran Prados, Schneider, Torben, Doshi, Anisha, Calvi, Alberto, Williams, Thomas, Plantone, Domenico, Monteverdi, Anita, MacManus, David, Marshall, Ian, Barkhof, Frederik, Gandini Wheeler‐Kingshott, Claudia A. M., Chataway, Jeremy

“…Background 1H‐magnetic resonance spectroscopy (1H‐MRS) may provide a direct index for the testing of medicines for neuroprotection and drug mechanisms in…”
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Multimodal Analysis of the Visual Pathways in Friedreich's Ataxia Reveals Novel Biomarkers by Thomas‐Black, Gilbert, Altmann, Daniel R., Crook, Harry, Solanky, Nita, Carrasco, Ferran Prados, Battiston, Marco, Grussu, Francesco, Yiannakas, Marios C., Kanber, Baris, Jolly, Jasleen K., Brett, Jon, Downes, Susan M., Moran, Marni, Chan, Ping K., Adewunmi, Emmanuel, Gandini Wheeler‐Kingshott, Claudia A.M., Németh, Andrea H., Festenstein, Richard, Bremner, Fion, Giunti, Paola

“…Background Optic neuropathy is a near ubiquitous feature of Friedreich's ataxia (FRDA). Previous studies have examined varying aspects of the anterior and…”
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Periventricular magnetisation transfer ratio abnormalities in multiple sclerosis improve after alemtuzumab by Brown, J William L, Prados Carrasco, Ferran, Eshaghi, Arman, Sudre, Carole H, Button, Tom, Pardini, Matteo, Samson, Rebecca S, Ourselin, Sebastien, Wheeler-Kingshott, Claudia Am Gandini, Jones, Joanne L, Coles, Alasdair J, Chard, Declan T

“…In multiple sclerosis (MS), disease effects on magnetisation transfer ratio (MTR) increase towards the ventricles. This periventricular gradient is evident…”
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Evaluating multiple sclerosis severity loci 30 years after a clinically isolated syndrome by Sahi, Nitin, Haider, Lukas, Chung, Karen, Prados Carrasco, Ferran, Kanber, Baris, Samson, Rebecca, Thompson, Alan J, Trip, S Anand, Brownlee, Wallace, Ciccarelli, Olga, Barkhof, Frederik, Tur, Carmen, Houlden, Henry, Chard, Declan

“…Abstract The first genome-wide significant multiple sclerosis severity locus, rs10191329, has been pathologically linked to cortical lesion load and brain…”
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Investigating the relationship between thalamic iron concentration and disease severity in secondary progressive multiple sclerosis using quantitative susceptibility mapping: Cross-sectional analysis from the MS-STAT2 randomised controlled trial by Williams, Thomas, John, Nevin, Calvi, Alberto, Bianchi, Alessia, De Angelis, Floriana, Doshi, Anisha, Wright, Sarah, Shatila, Madiha, Yiannakas, Marios C., Chowdhury, Fatima, Stutters, Jon, Ricciardi, Antonio, Prados, Ferran, MacManus, David, Grussu, Francesco, Karsa, Anita, Samson, Becky, Battiston, Marco, Gandini Wheeler-Kingshott, Claudia A.M., Shmueli, Karin, Ciccarelli, Olga, Barkhof, Frederik, Chataway, Jeremy, Chataway, Jeremy, Williams, Thomas, John, Nevin, De Angelis, Floriana, Calvi, Alberto, Bianchi, Alessia, Wright, Sarah, Shatila, Madiha, Doshi, Anisha, Brownlee, Wallace, Gandini Wheeler-Kingshott, Claudia AM, Barkhof, Frederik, Ciccarelli, Olga, Stutters, Jonathan, Carrasco, Ferran Prados, Ricciardi, Antonio, Yiannakas, Marios, MacManus, David, Wynne, Megan, Braisher, Marie, Blackstone, James, Hockey, Leanne, Parker, Josephine, Flight, Jennifer, Frost, Chris, Nicholas, Jennifer, Nixon, Stuart, Beveridge, Judy

“…Deep grey matter pathology is a key driver of disability worsening in people with multiple sclerosis. Quantitative susceptibility mapping (QSM) is an advanced…”
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