Výsledky vyhľadávania - "Practical laboratory medicine"

Liquid biopsy in cancer management: Integrating diagnostics and clinical applications Autor Pandey, Shashwat, Yadav, Preeti

“…Liquid biopsy is an innovative, minimally invasive diagnostic tool revolutionizing cancer management by enabling the detection and analysis of cancer-related…”
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Practical challenges related to point of care testing Autor Shaw, Julie L.V.

“…Point of care testing (POCT) refers to laboratory testing that occurs near to the patient, often at the patient bedside. POCT can be advantageous in situations…”
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Evaluation of creatine kinase (CK)-MB to total CK ratio as a diagnostic biomarker for primary tumors and metastasis screening Autor Li, Yan, Chen, Yongxin, Shao, Beibei, Liu, Junjun, Hu, Ruiguo, Zhao, Feng, Cui, Xiaofeng, Zhao, Xia, Wang, Yujiao

“…Creatine kinase (CK) and its myocardial band isoenzyme (CK-MB) were considered important diagnostic indicators for identifying suspected acute myocardial…”
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Biological variation: Understanding why it is so important? Autor Badrick, Tony

“…This Review will describe the increasing importance of the concepts of biological variation to clinical chemists. The idea of comparison to ‘reference’ is…”
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Biological function and molecular mechanism of piRNA in cancer Autor Chalbatani, Ghanbar Mahmoodi, Dana, Hassan, Memari, Feridon, Gharagozlou, Elahe, Ashjaei, Shirin, Kheirandish, Peyman, Marmari, Vahid, Mahmoudzadeh, Habibollah, Mozayani, Farnaz, Maleki, Ali Reza, Sadeghian, Ehsan, Nia, Elham Zainali, Miri, Seyed Rohollah, Nia, Neda zainali, Rezaeian, Omid, Eskandary, Anahita, Razavi, Narges, Shirkhoda, Mohammad, Rouzbahani, Fatemeh Nouri

“…Cancer is the second leading cause of death globally. piRNAs, which are a novel type of identified small noncoding RNA (ncRNA), play a crucial role in cancer…”
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Proteoforms and their expanding role in laboratory medicine Autor Forgrave, Lauren M., Wang, Meng, Yang, David, DeMarco, Mari L.

“…The term “proteoforms” describes the range of different structures of a protein product of a single gene, including variations in amino acid sequence and…”
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QbD based development of HPLC method for simultaneous quantification of Telmisartan and Hydrochlorothiazide impurities in tablets dosage form Autor Palakurthi, Ashok K., Dongala, Thirupathi, Katakam, Lakshmi Narasimha R.

“…A simple reverse phase liquid chromatographic gradient method has been developed and validated for the simultaneous determination of specified & un-specified…”
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Validation and implementation of a modular targeted capture assay for the detection of clinically significant molecular oncology alterations Autor Kuo, Ayako J., Paulson, Vera A., Hempelmann, Jennifer A., Beightol, Mallory, Todhunter, Sheena, Colbert, Brice G., Salipante, Stephen J., Konnick, Eric Q., Pritchard, Colin C., Lockwood, Christina M.

“…The rapid discovery of clinically significant genetic variants has translated to next-generation sequencing assays becoming out-of-date by the time they are…”
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Differences in serum and plasma levels of microRNAs and their time-course changes after blood collection Autor Wakabayashi, Ichiro, Marumo, Mikio, Ekawa, Kazumi, Daimon, Takashi

“…Serum and plasma are used for measurements of microRNAs (miRNAs) as biomarkers of various diseases. However, no consistent findings have been obtained…”
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Changing serum creatinine in the detection of acute renal failure and recovery following radiocontrast studies among acutely ill inpatients: Reviewing insights regarding renal functional reserve gained by large-data analysis Autor Gorelik, Yuri, Abassi, Zaid, Bloch-Isenberg, Natalie, Khamaisi, Mogher, Heyman, Samuel N.

“…A rise in serum creatinine (SCr) is widely used for the detection and definition of evolving acute kidney injury (AKI). Yet, it takes time for SCr to re-adjust…”
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Patient-based pre-classified real-time quality control with neural network (PCRTQC-NN) Autor Zhou, Bo, Li, Xiaoying, Cheng, Shitong, Zhou, Zhiwei, Kang, Hui

“…Patient-based real-time quality control (PBRTQC) is essential for clinical laboratory management but struggles with detecting small systematic errors. This…”
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Application of sigma-based quality control rules for the efficiency of internal quality control Autor Choi, Hyunji, Jeong, Ina, Cheon, Jeongeun, Park, Chul-Min, Lee, Sun Min

“…Ensuring stability in medical laboratories through quality control (QC) is crucial and requires fitted rules to prevent false alerts and identify errors. This…”
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Cyclical fluctuations of iron biomarkers in women: Diagnostic implications for iron deficiency Autor Aguree, Sixtus, Owora, Arthur, Silveyra, Patricia

“…Iron deficiency (ID) and iron deficiency anemia (IDA) are common in women of reproductive age, but the influence of menstrual cycle phase on iron biomarkers is…”
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Towards the clinical use of peripheral bile acids: Recommendations to limit their preanalytical and analytical sources of variability Autor Joseph, Sebastian, de Buyl, Sophie, Leclercq, Isabelle A., Serafimov, Kristian, Feron, Olivier, Clerbaux, Laure-Alix

“…Despite more than three decades of research, the use of peripheral bile acids as biomarkers for human liver injury remains inconclusive due to inconsistent…”
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Comparative validation of low-density lipoprotein cholesterol estimation formulas in older Georgian adults Autor Nino, Gagua, Lizi, Mokvanidze, Nino, Kekenadze

“…Low-density lipoprotein cholesterol (LDL-C) is a critical marker for cardiovascular risk assessment. Although direct measurement offers high accuracy, it is…”
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Performance evaluation of the new Dymind automated hematology analyzer Autor Penglong, Tipparat, Tepakhan, Wanicha, Tehyoh, Nasra, Songkhla, Yanisa Na, Songnak, Chakkrit, Srinoun, Kanitta

“…The Dymind automated hematology analyzer includes the five-part analyzers DF55 and DH76 and the six-part analyzer DH615, which features reticulocyte parameters…”
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Flow cytometry-based validation of soluble biomarker detection Autor Tang, Yiting, Wu, Xiang, Zhang, Huating, Dong, Liu, Cao, Ruoshui, Chen, Jian, Zhu, Jiajun, Hu, Lianlong, Zhou, Qingyu, Zhou, Jianming, Qian, Ke, Lin, Yong, Chen, Shuying

“…Accurate and reliable measurement of soluble markers, such as sCD25, sCD40L, sCD130, and sTREM-1, is crucial for understanding their roles in immune responses…”
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Can the icteric index be used instead of total bilirubin in addition to being a preanalytical marker? Icteric index in the laboratory Autor Odabasi, Merve Sena, Yalcinkaya Kara, Zeynep Mine

“…The icteric index (I-index) is a practical and low-cost method for screening hyperbilirubinemia and potentially reducing unnecessary total bilirubin (TBil)…”
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Advancements in laboratory diagnostics for HIV/MTB coinfection: Integrating conventional methods with emerging technologies Autor Li, Yu, Wei, Hongjuan, Sun, Limei, Tang, Dongsong, Wang, Tiantian, Yu, Yanhua

“…Individuals infected with the Human Immunodeficiency Virus (HIV) face an elevated risk of Mycobacterium tuberculosis (MTB) infection. Clinical diagnosis of…”
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Analytical validation of a scrape-free multitarget stool RNA test for colorectal cancer screening Autor Barnell, Erica K., Kruse, Kimberly, Wurtzler, Elizabeth M., Scott, Maya Crowder, Barnell, Andrew R., Duncavage, Eric J.

“…Traditional stool-based colorectal cancer (CRC) screening tests require patients to collect and swab their own stool, which can reduce adherence due to…”
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