Suchergebnisse - "Plaque, Atherosclerotic"

Complicated Carotid Artery Plaques and Risk of Recurrent Ischemic Stroke or TIA von Kopczak, Anna, Schindler, Andreas, Sepp, Dominik, Bayer-Karpinska, Anna, Malik, Rainer, Koch, Mia L, Zeller, Julia, Strecker, Christoph, Janowitz, Daniel, Wollenweber, Frank A, Hempel, Johann-Martin, Boeckh-Behrens, Tobias, Cyran, Clemens C, Helck, Andreas, Harloff, Andreas, Ziemann, Ulf, Poli, Sven, Poppert, Holger, Saam, Tobias, Dichgans, Martin

“… Complicated nonstenosing carotid artery plaques (CAPs) are an under-recognized cause of stroke. The purpose of this study was to determine whether complicated …”
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Microplastics and Nanoplastics in Atheromas and Cardiovascular Events von Marfella, Raffaele, Prattichizzo, Francesco, Sardu, Celestino, Fulgenzi, Gianluca, Graciotti, Laura, Spadoni, Tatiana, D’Onofrio, Nunzia, Scisciola, Lucia, La Grotta, Rosalba, Frigé, Chiara, Pellegrini, Valeria, Municinò, Maurizio, Siniscalchi, Mario, Spinetti, Fabio, Vigliotti, Gennaro, Vecchione, Carmine, Carrizzo, Albino, Accarino, Giulio, Squillante, Antonio, Spaziano, Giuseppe, Mirra, Davida, Esposito, Renata, Altieri, Simona, Falco, Giovanni, Fenti, Angelo, Galoppo, Simona, Canzano, Silvana, Sasso, Ferdinando C., Matacchione, Giulia, Olivieri, Fabiola, Ferraraccio, Franca, Panarese, Iacopo, Paolisso, Pasquale, Barbato, Emanuele, Lubritto, Carmine, Balestrieri, Maria L., Mauro, Ciro, Caballero, Augusto E., Rajagopalan, Sanjay, Ceriello, Antonio, D’Agostino, Bruno, Iovino, Pasquale, Paolisso, Giuseppe

“… Patients with evidence of microplastics and nanoplastics in carotid artery plaque, as compared with patients without, had a greater risk of adverse …”
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Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis von Takaoka, Minoru, Zhao, Xiaohui, Lim, Hwee Ying, Magnussen, Costan G., Ang, Owen, Suffee, Nadine, Schrank, Patricia R., Ong, Wei Siong, Tsiantoulas, Dimitrios, Sommer, Felix, Mohanta, Sarajo K., Harrison, James, Meng, Yaxing, Laurans, Ludivine, Wu, Feitong, Lu, Yuning, Masters, Leanne, Newland, Stephen A., Denti, Laura, Hong, Mingyang, Chajadine, Mouna, Juonala, Markus, Koskinen, Juhani S., Kähönen, Mika, Pahkala, Katja, Rovio, Suvi P., Mykkänen, Juha, Thomson, Russell, Kaisho, Tsuneyasu, Habenicht, Andreas J. R., Clement, Marc, Tedgui, Alain, Ait-Oufella, Hafid, Zhao, Tian X., Nus, Meritxell, Ruhrberg, Christiana, Taleb, Soraya, Williams, Jesse W., Raitakari, Olli T., Angeli, Véronique, Mallat, Ziad

“… Hyperlipidaemia is a major risk factor of atherosclerotic cardiovascular disease (ASCVD). Risk of cardiovascular events depends on cumulative lifetime exposure …”
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Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype von Rademakers, Timo, Manca, Marco, Jin, Han, Orban, Tanguy, Perisic, Ljubica Matic, Frissen, Hubertus J. M., Rühle, Frank, Hautvast, Petra, van Rijssel, Jos, van Kuijk, Kim, Mees, Barend M. E., Peutz-Kootstra, Carine J., Heeneman, Sylvia, Daemen, Mat J. A. P., Pasterkamp, Gerard, Stoll, Monika, van Zandvoort, Marc A. M. J., Hedin, Ulf, Dequiedt, Franck, van Buul, Jaap D., Sluimer, Judith C., Biessen, Erik A. L.

“… The presence of atherosclerotic plaque vessels is a critical factor in plaque destabilization. This may be attributable to the leaky phenotype of these …”
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Exercise and Coronary Atherosclerosis: Observations, Explanations, Relevance, and Clinical Management von Aengevaeren, Vincent L, Mosterd, Arend, Sharma, Sanjay, Prakken, Niek H J, Möhlenkamp, Stefan, Thompson, Paul D, Velthuis, Birgitta K, Eijsvogels, Thijs M H

“… Physical activity and exercise training are effective strategies for reducing the risk of cardiovascular events, but multiple studies have reported an …”
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Animal models of atherosclerosis von Emini Veseli, Besa, Perrotta, Paola, De Meyer, Gregory R.A., Roth, Lynn, Van der Donckt, Carole, Martinet, Wim, De Meyer, Guido R.Y.

“… An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology and has the potential to be used in medical and pharmaceutical research to …”
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Boosting Inflammation Resolution in Atherosclerosis: The Next Frontier for Therapy von Fredman, Gabrielle, Tabas, Ira

“… Defective inflammation resolution is the underlying cause of prevalent chronic inflammatory diseases, such as arthritis, asthma, cancer, and neurodegenerative …”
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Atherosclerotic Plaque Healing von Vergallo, Rocco, Crea, Filippo

“… Atherosclerotic plaque rupture and erosion result in acute coronary syndromes. Plaque healing after initial disruption has been less extensively studied …”
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Macrophages in Atherosclerosis Regression von Barrett, Tessa J

“… Macrophages play a central role in the development of atherosclerotic cardiovascular disease (ASCVD), which encompasses coronary artery disease, peripheral …”
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A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography von Oikonomou, Evangelos K, Williams, Michelle C, Kotanidis, Christos P, Desai, Milind Y, Marwan, Mohamed, Antonopoulos, Alexios S, Thomas, Katharine E, Thomas, Sheena, Akoumianakis, Ioannis, Fan, Lampson M, Kesavan, Sujatha, Herdman, Laura, Alashi, Alaa, Centeno, Erika Hutt, Lyasheva, Maria, Griffin, Brian P, Flamm, Scott D, Shirodaria, Cheerag, Sabharwal, Nikant, Kelion, Andrew, Dweck, Marc R, Van Beek, Edwin J R, Deanfield, John, Hopewell, Jemma C, Neubauer, Stefan, Channon, Keith M, Achenbach, Stephan, Newby, David E, Antoniades, Charalambos

“… Abstract Background Coronary inflammation induces dynamic changes in the balance between water and lipid content in perivascular adipose tissue (PVAT), as …”
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Investigation of Wall Shear Stress in Cardiovascular Research and in Clinical Practice—From Bench to Bedside von Urschel, Katharina, Tauchi, Miyuki, Achenbach, Stephan, Dietel, Barbara

“… In the 1900s, researchers established animal models experimentally to induce atherosclerosis by feeding them with a cholesterol-rich diet. It is now accepted …”
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Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial von Räber, Lorenz, Ueki, Yasushi, Otsuka, Tatsuhiko, Losdat, Sylvain, Häner, Jonas D, Lonborg, Jacob, Fahrni, Gregor, Iglesias, Juan F, van Geuns, Robert-Jan, Ondracek, Anna S, Radu Juul Jensen, Maria D, Zanchin, Christian, Stortecky, Stefan, Spirk, David, Siontis, George C M, Saleh, Lanja, Matter, Christian M, Daemen, Joost, Mach, François, Heg, Dik, Windecker, Stephan, Engstrøm, Thomas, Lang, Irene M, Koskinas, Konstantinos C

“… Coronary plaques that are prone to rupture and cause adverse cardiac events are characterized by large plaque burden, large lipid content, and thin fibrous …”
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Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo von Lewis, Daniel R, Petersen, Latrisha K, York, Adam W, Zablocki, Kyle R, Joseph, Laurie B, Kholodovych, Vladyslav, Prud'homme, Robert K, Uhrich, Kathryn E, Moghe, Prabhas V

“… Atherosclerosis, the build-up of occlusive, lipid-rich plaques in arterial walls, is a focal trigger of chronic coronary, intracranial, and peripheral arterial …”
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Inhibition of plaque progression and promotion of plaque stability by glucagon-like peptide-1 receptor agonist: Serial in vivo findings from iMap-IVUS in Watanabe heritable hyperlipidemic rabbits von Sudo, Mitsumasa, Li, Yuxin, Hiro, Takafumi, Takayama, Tadateru, Mitsumata, Masako, Shiomi, Masashi, Sugitani, Masahiko, Matsumoto, Taro, Hao, Hiroyuki, Hirayama, Atsushi

“… Glucagon-like peptide-1 (GLP-1) is thought to inhibit development of aortic atherosclerosis and plaque formation. However, whether GLP-1 stabilizes fully …”
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Inflammation and plaque vulnerability von Hansson, G. K., Libby, P., Tabas, I.

“… Atherosclerosis is a maladaptive, nonresolving chronic inflammatory disease that occurs at sites of blood flow disturbance. The disease usually remains silent …”
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Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis von Parma, Laura, Baganha, Fabiana, Quax, Paul H.A., de Vries, Margreet R.

“… Acute cardiovascular events, due to rupture or erosion of an atherosclerotic plaque, represent the major cause of morbidity and mortality in patients. Growing …”
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Single-cell immune landscape of human atherosclerotic plaques von Fernandez, Dawn M, Rahman, Adeeb H, Fernandez, Nicolas F, Chudnovskiy, Aleksey, Amir, El-Ad David, Amadori, Letizia, Khan, Nayaab S, Wong, Christine K, Shamailova, Roza, Hill, Christopher A, Wang, Zichen, Remark, Romain, Li, Jennifer R, Pina, Christian, Faries, Christopher, Awad, Ahmed J, Moss, Noah, Bjorkegren, Johan L M, Kim-Schulze, Seunghee, Gnjatic, Sacha, Ma'ayan, Avi, Mocco, J, Faries, Peter, Merad, Miriam, Giannarelli, Chiara

“… Atherosclerosis is driven by multifaceted contributions of the immune system within the circulation and at vascular focal sites. However, specific …”
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Targeting the CCL2-CCR2 axis for atheroprotection von Georgakis, Marios K, Bernhagen, Jürgen, Heitman, Laura H, Weber, Christian, Dichgans, Martin

“… Decades of research have established atherosclerosis as an inflammatory disease. Only recently though, clinical trials provided proof-of-concept evidence for …”
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Sulfhydrated Sirtuin-1 Increasing Its Deacetylation Activity Is an Essential Epigenetics Mechanism of Anti-Atherogenesis by Hydrogen Sulfide von Du, Congkuo, Lin, Xianjuan, Xu, Wenjing, Zheng, Fengjiao, Cai, Junyan, Yang, Jichun, Cui, Qinghua, Tang, Chaoshu, Cai, Jun, Xu, Guoheng, Geng, Bin

“… Hydrogen sulfide (H2S) has a protective role in the pathogenesis of atherosclerosis by multiple pathways. Sirtuin-1 ( ) is a histone deacetylase, as an …”
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Empagliflozin ameliorates endothelial dysfunction and suppresses atherogenesis in diabetic apolipoprotein E-deficient mice von Ganbaatar, Byambasuren, Fukuda, Daiju, Shinohara, Masakazu, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Hirata, Ken-ichi, Sata, Masataka

“… Recent studies reported cardioprotective effects of sodium glucose co-transporter 2 (SGLT2) inhibitors; however, the underlying mechanisms are still obscure …”
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