Suchergebnisse - "Perren, Aurel"

Overview of the 2022 WHO Classification of Parathyroid Tumors von Erickson, Lori A., Mete, Ozgur, Juhlin, C. Christofer, Perren, Aurel, Gill, Anthony J.

“… The 2022 WHO classification reflects increases in the knowledge of the underlying pathogenesis of parathyroid disease. In addition to the classic …”
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Spatially restricted tumour-associated and host-associated immune drivers correlate with the recurrence sites of pancreatic cancer von Karamitopoulou, Eva, Wenning, Anna Silvia, Acharjee, Animesh, Zlobec, Inti, Aeschbacher, Pauline, Perren, Aurel, Gloor, Beat

“… ObjectiveMost patients with pancreatic ductal adenocarcinoma (PDAC) will experience recurrence after resection. Here, we investigate spatially organised immune …”
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The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms von Venizelos, Andreas, Elvebakken, Hege, Perren, Aurel, Nikolaienko, Oleksii, Deng, Wei, Lothe, Inger Marie B, Couvelard, Anne, Hjortland, Geir Olav, Sundlöv, Anna, Svensson, Johanna, Garresori, Harrish, Kersten, Christian, Hofsli, Eva, Detlefsen, Sönke, Krogh, Merete, Sorbye, Halfdan, Knappskog, Stian

“… High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare but have a very poor prognosis and represent a severely understudied class …”
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Overview of the 2022 WHO Classification of Familial Endocrine Tumor Syndromes von Nosé, Vania, Gill, Anthony, Teijeiro, José Manuel Cameselle, Perren, Aurel, Erickson, Lori

“… This review of the familial tumor syndromes involving the endocrine organs is focused on discussing the main updates on the upcoming fifth edition of the WHO …”
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ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Pathology: Diagnosis and Prognostic Stratification von Perren, Aurel, Couvelard, Anne, Scoazec, Jean-Yves, Costa, Frederico, Borbath, Ivan, Delle Fave, Gianfranco, Gorbounova, Vera, Gross, David, Grossma, Ashley, Jense, Robert T, Kulke, Matthew, Oeberg, Kjell, Rindi, Guido, Sorbye, Halfdan, Welin, Staffan

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ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics von Liu, He, He, Zhaoyue, Germič, Nina, Ademi, Hyrijie, Frangež, Živa, Felser, Andrea, Peng, Shuang, Riether, Carsten, Djonov, Valentin, Nuoffer, Jean-Marc, Bovet, Cédric, Mlinarič-Raščan, Irena, Zlobec, Inti, Fiedler, Martin, Perren, Aurel, Simon, Hans-Uwe

“… In contrast to the "Warburg effect" or aerobic glycolysis earlier generalized as a phenomenon in cancer cells, more and more recent evidence indicates that …”
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Multiple Endocrine Neoplasia Type 1 and the Pancreas: Diagnosis and Treatment of Functioning and Non-Functioning Pancreatic and Duodenal Neuroendocrine Neoplasia within the MEN1 Syndrome - An International Consensus Statement von Niederle, Bruno, Selberherr, Andreas, Bartsch, Detlef K, Brandi, Maria L, Doherty, Gerard M, Falconi, Massimo, Goudet, Pierre, Halfdanarson, Thorvardur R, Ito, Tetsuhide, Jensen, Robert T, Larghi, Alberto, Lee, Lingaku, Öberg, Kjell, Pavel, Marianne, Perren, Aurel, Sadowski, Samira M, Tonelli, Francesco, Triponez, Frédéric, Valk, Gerlof D, O'Toole, Dermot, Scott-Coombes, David, Thakker, Rajesh V, Thompson, Geoffrey B, Treglia, Giorgio, Wiedenmann, Bertram

“… The better understanding of the biological behavior of multiple endocrine neoplasia type 1 (MEN1) organ manifestations and the increase in clinical experience …”
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Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression von Di Domenico, Annunziata, Pipinikas, Christodoulos P., Maire, Renaud S., Bräutigam, Konstantin, Simillion, Cedric, Dettmer, Matthias S., Vassella, Erik, Thirlwell, Chrissie, Perren, Aurel, Marinoni, Ilaria

“… Recent data suggest that Pancreatic Neuroendocrine Tumours (PanNETs) originate from α- or β-cells of the islets of Langerhans. The majority of PanNETs are …”
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Evidence of a common cell origin in a case of pancreatic mixed intraductal papillary mucinous neoplasm–neuroendocrine tumor von Schiavo Lena, Marco, Cangi, Maria Giulia, Pecciarini, Lorenza, Francaviglia, Ilaria, Grassini, Greta, Maire, Renaud, Partelli, Stefano, Falconi, Massimo, Perren, Aurel, Doglioni, Claudio

“… Recently, the term mixed neuroendocrine non-neuroendocrine neoplasms (MiNEN) has been proposed as an umbrella definition covering different possible …”
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Editorial Expression of Concern: ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy von Maskey, Dipak, Yousefi, Shida, Schmid, Inès, Zlobec, Inti, Perren, Aurel, Friis, Robert, Simon, Hans-Uwe

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The Gastroenteropancreatic Neuroendocrine Cell System and Its Tumors: The WHO Classification von KLÖPPEL, GÜNTER, PERREN, AUREL, HEITZ, PHILIPP U.

“… : Although well established in medical terminology, the term carcinoid is no longer adequate to cover the entire morphological and biological spectrum of …”
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Autophagy Inhibition Improves Sunitinib Efficacy in Pancreatic Neuroendocrine Tumors via a Lysosome-dependent Mechanism von Wiedmer, Tabea, Blank, Annika, Pantasis, Sophia, Normand, Lea, Bill, Ruben, Krebs, Philippe, Tschan, Mario P, Marinoni, Ilaria, Perren, Aurel

“… Increasing the efficacy of approved systemic treatments in metastasized pancreatic neuroendocrine tumors (PanNET) is an unmet medical need. The antiangiogenic …”
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ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy von Maskey, Dipak, Yousefi, Shida, Schmid, Inès, Zlobec, Inti, Perren, Aurel, Friis, Robert, Simon, Hans-Uwe

“… Anticancer drug therapy activates both molecular cell death and autophagy pathways. Here we show that even sublethal concentrations of DNA-damaging drugs, such …”
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Surgery with Radical Intent: Is There an Indication for G3 Neuroendocrine Neoplasms? von Merola, Elettra, Rinke, Anja, Partelli, Stefano, Gress, Thomas M., Andreasi, Valentina, Kollár, Attila, Perren, Aurel, Christ, Emanuel, Panzuto, Francesco, Pascher, Andreas, Jann, Henning, Arsenic, Ruza, Cremer, Birgit, Kaemmerer, Daniel, Kump, Patrizia, Lipp, Rainer W., Agaimy, Abbas, Wiedenmann, Bertram, Falconi, Massimo, Pavel, Marianne E.

“… Background While platinum-based chemotherapy represents the standard treatment for advanced grade 3 (G3) neuroendocrine neoplasms (NENs) according to the …”
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Basic science and translational implications of current knowledge on neuroendocrine tumors von Fernandez-Cuesta, Lynnette, Alcala, Nicolas, Mathian, Emilie, Derks, Jules, Thirlwell, Chrissie, Dayton, Talya, Marinoni, Ilaria, Perren, Aurel, Walter, Thomas, Foll, Matthieu

“… Neuroendocrine tumors (NETs) are a diverse group of malignancies that can occur in various organs, with a notable prevalence in the lungs and gastrointestinal …”
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Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting von Körner, Meike, Waser, Beatrice, Schonbrunn, Agnes, Perren, Aurel, Reubi, Jean Claude

“… High overexpression of somatostatin receptors in neuroendocrine tumors allows imaging and radiotherapy with radiolabeled somatostatin analogues. To ascertain …”
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Comprehensive MicroRNA expression profiling identifies novel markers in follicular variant of papillary thyroid carcinoma von Dettmer, Matthias, Perren, Aurel, Moch, Holger, Komminoth, Paul, Nikiforov, Yuri E, Nikiforova, Marina N

“… Follicular variant of papillary thyroid carcinoma (FVPTC) shares features of papillary (PTC) and follicular (FTC) thyroid carcinomas on a clinical, …”
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The ENETS and AJCC/UICC TNM classifications of the neuroendocrine tumors of the gastrointestinal tract and the pancreas: a statement von Klöppel, Günter, Rindi, Guido, Perren, Aurel, Komminoth, Paul, Klimstra, David S.

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Müller matrix polarimetry for pancreatic tissue characterization von Sampaio, Paulo, Lopez-Antuña, Maria, Storni, Federico, Wicht, Jonatan, Sökeland, Greta, Wartenberg, Martin, Márquez-Neila, Pablo, Candinas, Daniel, Demory, Brice-Olivier, Perren, Aurel, Sznitman, Raphael

“… Polarimetry is an optical characterization technique capable of analyzing the polarization state of light reflected by materials and biological samples. In …”
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Tall cell papillary thyroid carcinoma: new diagnostic criteria and mutations in BRAF and TERT von Dettmer, Matthias S, Schmitt, Anja, Steinert, Hans, Capper, David, Moch, Holger, Komminoth, Paul, Perren, Aurel

“… The tall cell (TC) variant of papillary thyroid carcinoma (PTC) has an unfavorable prognosis. The diagnostic criteria remain inconsistent, and the role of a …”
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