Suchergebnisse - "Pepe, S."

Diagnostic concordance among pathologists interpreting breast biopsy specimens von Elmore, Joann G, Longton, Gary M, Carney, Patricia A, Geller, Berta M, Onega, Tracy, Tosteson, Anna N A, Nelson, Heidi D, Pepe, Margaret S, Allison, Kimberly H, Schnitt, Stuart J, O'Malley, Frances P, Weaver, Donald L

“… A breast pathology diagnosis provides the basis for clinical treatment and management decisions; however, its accuracy is inadequately understood. To quantify …”
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Problems with risk reclassification methods for evaluating prediction models von Pepe, Margaret S

“… For comparing the performance of a baseline risk prediction model with one that includes an additional predictor, a risk reclassification analysis strategy has …”
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Pathologists’ diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study von Elmore, Joann G, Barnhill, Raymond L, Elder, David E, Longton, Gary M, Pepe, Margaret S, Reisch, Lisa M, Carney, Patricia A, Titus, Linda J, Nelson, Heidi D, Onega, Tracy, Tosteson, Anna N A, Weinstock, Martin A, Knezevich, Stevan R, Piepkorn, Michael W

“… Objective To quantify the accuracy and reproducibility of pathologists’ diagnoses of melanocytic skin lesions.Design Observer accuracy and reproducibility …”
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Adjusting for covariates in studies of diagnostic, screening, or prognostic markers: an old concept in a new setting von Janes, Holly, Pepe, Margaret S

“… The concept of covariate adjustment is well established in therapeutic and etiologic studies. However, it has received little attention in the growing area of …”
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Pivotal evaluation of the accuracy of a biomarker used for classification or prediction: standards for study design von Pepe, Margaret S, Feng, Ziding, Janes, Holly, Bossuyt, Patrick M, Potter, John D

“… Research methods for biomarker evaluation lag behind those for evaluating therapeutic treatments. Although a phased approach to development of biomarkers …”
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Assessing the value of risk predictions by using risk stratification tables von Janes, Holly, Pepe, Margaret S, Gu, Wen

“… The recent epidemiologic and clinical literature is filled with studies evaluating statistical models for predicting disease or some other adverse event. Risk …”
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Early-Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility? von Pepe, Margaret S, Janes, Holly, Li, Christopher I, Bossuyt, Patrick M, Feng, Ziding, Hilden, Jørgen

“… Many cancer biomarker research studies seek to develop markers that can accurately detect or predict future onset of disease. To design and evaluate these …”
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The 21 August 2017 Ischia (Italy) Earthquake Source Model Inferred From Seismological, GPS, and DInSAR Measurements von De Novellis, V., Carlino, S., Castaldo, R., Tramelli, A., De Luca, C., Pino, N. A., Pepe, S., Convertito, V., Zinno, I., De Martino, P., Bonano, M., Giudicepietro, F., Casu, F., Macedonio, G., Manunta, M., Cardaci, C., Manzo, M., Di Bucci, D., Solaro, G., Zeni, G., Lanari, R., Bianco, F., Tizzani, P.

“… The causative source of the first damaging earthquake instrumentally recorded in the Island of Ischia, occurred on 21 August 2017, has been studied through a …”
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Adjusting for covariate effects on classification accuracy using the covariate-adjusted receiver operating characteristic curve von Janes, Holly, Pepe, Margaret S

“… Recent scientific and technological innovations have produced an abundance of potential markers that are being investigated for their use in disease screening …”
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DInSAR Analysis and Analytical Modeling of Mount Etna Displacements: The December 2018 Volcano‐Tectonic Crisis von De Novellis, V., Atzori, S., De Luca, C., Manzo, M., Valerio, E., Bonano, M., Cardaci, C., Castaldo, R., Di Bucci, D., Manunta, M., Onorato, G., Pepe, S., Solaro, G., Tizzani, P., Zinno, I., Neri, M., Lanari, R., Casu, F.

“… We investigate the 24–27 December 2018 eruption of Mount Etna occurred from fissures located on the volcano eastern flank and accompanied by a seismic swarm, …”
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Ground deformation and source geometry of the 24 August 2016 Amatrice earthquake (Central Italy) investigated through analytical and numerical modeling of DInSAR measurements and structural‐geological data von Lavecchia, G., Castaldo, R., Nardis, R., De Novellis, V., Ferrarini, F., Pepe, S., Brozzetti, F., Solaro, G., Cirillo, D., Bonano, M., Boncio, P., Casu, F., De Luca, C., Lanari, R., Manunta, M., Manzo, M., Pepe, A., Zinno, I., Tizzani, P.

“… We investigate the ground deformation and source geometry of the 2016 Amatrice earthquake (Central Italy) by exploiting ALOS2 and Sentinel‐1 coseismic …”
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Estimation and Comparison of Receiver Operating Characteristic Curves von Pepe, Margaret, Longton, Gary, Janes, Holly

“… The receiver operating characteristic (ROC) curve displays the capacity of a marker or diagnostic test to discriminate between two groups of subjects, cases …”
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Data Dictionaries: Essential Tools for the Ethical and Transparent Use of Integrated Data von Pepe, Rebecca S., Coe, Kristen

“… Data transparency lays the groundwork for the ethical use of administrative data. This is particularly true for linked administrative data within integrated …”
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Time-Dependent ROC Curves for Censored Survival Data and a Diagnostic Marker von Heagerty, Patrick J., Lumley, Thomas, Pepe, Margaret S.

“… ROC curves are a popular method for displaying sensitivity and specificity of a continuous diagnostic marker, X, for a binary disease variable, D. However, …”
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Measuring the performance of markers for guiding treatment decisions von Janes, Holly, Pepe, Margaret S, Bossuyt, Patrick M, Barlow, William E

“… Treatment selection markers, sometimes called predictive markers, are factors that help clinicians select therapies that maximize good outcomes and minimize …”
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Volcanic structures investigation through SAR and seismic interferometric methods: The 2011–2013 Campi Flegrei unrest episode von Pepe, S., De Siena, L., Barone, A., Castaldo, R., D'Auria, L., Manzo, M., Casu, F., Fedi, M., Lanari, R., Bianco, F., Tizzani, P.

“… Observations from satellites provide high-resolution images of ground deformation allowing to infer deformation sources by developing advanced modeling of …”
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Partial AUC Estimation and Regression von Dodd, Lori E., Pepe, Margaret S.

“… Accurate diagnosis of disease is a critical part of health care. New diagnostic and screening tests must be evaluated based on their abilities to discriminate …”
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Integrating the predictiveness of a marker with its performance as a classifier von Pepe, Margaret S, Feng, Ziding, Huang, Ying, Longton, Gary, Prentice, Ross, Thompson, Ian M, Zheng, Yingye

“… There are two popular statistical approaches to biomarker evaluation. One models the risk of disease (or disease outcome) with, for example, logistic …”
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Predicting Obesity in Young Adulthood from Childhood and Parental Obesity von Whitaker, Robert C, Wright, Jeffrey A, Pepe, Margaret S, Seidel, Kristy D, Dietz, William H

“… The prevalence of obesity has increased in both children and adults. 1 , 2 The medical illnesses associated with obesity 3 usually occur in adulthood, but …”
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New insights into the 2012 Emilia (Italy) seismic sequence through advanced numerical modeling of ground deformation InSAR measurements von Tizzani, P., Castaldo, R., Solaro, G., Pepe, S., Bonano, M., Casu, F., Manunta, M., Manzo, M., Pepe, A., Samsonov, S., Lanari, R., Sansosti, E.

“… We provide new insights into the two main seismic events that occurred in 2012 in the Emilia region, Italy. We extend the results from previous studies based …”
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