Výsledky vyhľadávania - "Peng, Yuce"

iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation Autor Guo, Yongzheng, Wen, Junjie, He, An, Qu, Can, Peng, Yuce, Luo, Suxin, Wang, Xiaowen

“…[Display omitted] •Combination of HDF and L-NAME induced cardiac mitochondrial dysfunction and HFpEF phenotype.•Both long-term and short-term iNOS inhibition…”
Získať plný text

Melatonin alleviates sepsis-induced acute lung injury by inhibiting necroptosis via reducing circulating mtDNA release Autor Peng, Yuce, Xu, Jia, Wei, Lingyu, Luo, Minghao, Chen, Shenglong, Wei, Xuebiao, Luo, Suxin, Su, Zedazhong, Wang, Zhonghua

“…Background Sepsis is a life-threatening condition that often leads to severe complications, including acute lung injury (ALI), which carries high morbidity and…”
Získať plný text

Dapagliflozin ameliorates myocardial infarction injury through AMPKα-dependent regulation of oxidative stress and apoptosis Autor Peng, Yuce, Guo, Mingyu, Luo, Minghao, Lv, Dingyi, Liao, Ke, Luo, Suxin, Zhang, Bingyu

“…Dapagliflozin (DAPA) has been demonstrated to reduce cardiovascular mortality and heart failure hospitalization rates in diabetic patients. However, the…”
Získať plný text

LncRNA GAS5 downregulates NLRP3 inflammasome activation-mediated pyroptosis in sepsis-induced myocardial injury by targeting SIRT3/AMPKα Autor Luo, Minghao, Peng, Yuce, Lv, Dingyi, Xue, Yuzhou, Huang, Longxiang, Hu, Yu, Zhu, Wenyan, Luo, Suxin, Shen, Jian, Li, Xiang

“…An increasing body of studies has demonstrated the significance of long non-coding RNA (lncRNA) growth arrest specific 5 (GAS5) in inflammation and myocardial…”
Získať plný text

Inhibition of Stimulator of Interferon Genes Protects Against Myocardial Ischemia-Reperfusion Injury in Diabetic Mice Autor Peng, Yuce, Zhou, Guoxiang, Guo, Mingyu, Cheng, Zhe, Luo, Suxin, Guo, Yongzheng

“…Background: Although the past decade has witnessed substantial scientific progress with the advent of cardioprotective pharmacological agents, most have failed…”
Získať plný text

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis Autor Zuo, Deyu, Peng, Yuce, Zhao, Guozhi, Cheng, Zhesheng, Luo, Minghao, Lv, Dingyi, Chang, Shuting, Li, Na, Huang, Yanyao, Li, Xunjia, He, An

“…Hypoglycemia is a commonly neglected complication in elderly diabetic patients, which can lead to cardiovascular events. Endothelial cell dysfunction is the…”
Získať plný text

Prognostic value of red cell distribution width in non-ST elevation myocardial infarction: A cohort study Autor Peng, Yuce, Sasmita, Byran Richard, Luo, Suxin

“…Non-ST elevation myocardial infarction (NSTEMI) has a higher risk of long-term mortality than ST-elevation myocardial infarction; thus, identifying such…”
Získať plný text

Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine Autor Wu, Mengze, Chen, Guodong, Peng, Yuce, Luo, Suxin

“…Heart failure (HF) is the end stage of many cardiovascular diseases, which is often associated with myocardial hypertrophy and cardiac remodeling. Among them,…”
Získať plný text

Identification of necroptotic biomarkers associated with immune microenvironment in sepsis based on the protein–protein interaction network and machine learning Autor Wu, Mengze, Zou, Zhao, Peng, Yuce, Luo, Suxin

“…•Machine learning and protein-protein interaction network identify CD40LG, TXN, and AIM2 as the key players of necroptosis in sepsis.•CD40LG, TXN, and AIM2…”
Získať plný text

Transcriptomic bioinformatics analysis proposes a novel BCL2-MAPK14-TXN oxidative stress diagnostic model of sepsis and identifies TXN as an oxidative stress-related signature gene in sepsis Autor Zou, Zhao, Wu, Mengze, Peng, Yuce, Luo, Suxin

“…Background: Oxidative stress was one of key factors driving the septic development by the uncontrolled accumulation of free radicals, thus oxidative…”
Získať plný text

Combination of machine learning and protein-protein interaction network established one ATM-DPP4-TXN ferroptotic diagnostic model with experimental validation Autor Wu, Mengze, Zou, Zhao, Peng, Yuce, Luo, Suxin

“…Ferroptosis and lethal sepsis are interlinked, although this association remains largely unknown to clinical panels. Sepsis is characterized by dysfunction of…”
Získať plný text

Diacerein attenuates sepsis shock mortality through combined suppression of vascular inflammation, stiffness, and permeability Autor Luo, Minghao, Jiang, Yi, Peng, Yuce, Lv, Dingyi, He, An, Huang, Longxiang, Xia, Yong, Luo, Suxin, Li, Yuanjing

“…Sepsis shock mortality remains critically high due to dysregulated vascular inflammation and permeability. Diacerein (DIA), an anthraquinone derivative with…”
Získať plný text

Esomeprazole inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia-reperfusion injury Autor Zhou, Guoxiang, Peng, Yuce, Guo, Mingyu, Qu, Can, Luo, Suxin, Jiang, Yingjiu, Chen, Dan, Wang, Xiaowen, Guo, Yongzheng

“…Proton pump inhibitors (PPIs) are often prescribed in association with clopidogrel and aspirin to patients with myocardial infraction (MI), but their effects…”
Získať plný text

Macrophage KDM2A promotes atherosclerosis via regulating FYN and inducing inflammatory response Autor Xue, Yuzhou, Peng, Yuce, Jin, Ling, Liu, Lin, Liu, Qian, Yuan, Xiaofan, Wang, Jingyu, Zhao, Mingming, Zhang, Wenming, Luo, Suxin, Li, Yuanjing, Luo, Minghao, Huang, Longxiang

“…Macrophage inflammatory response is the key driver in atherosclerosis development. However, transcriptional remodeling of macrophage inflammatory response…”
Získať plný text