Suchergebnisse - "Pasvol, Geoffrey"

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis von Mousa, Andria, Al-Taiar, Abdullah, Anstey, Nicholas M., Badaut, Cyril, Barber, Bridget E., Bassat, Quique, Challenger, Joseph D., Cunnington, Aubrey J., Datta, Dibyadyuti, Drakeley, Chris, Ghani, Azra C., Gordeuk, Victor R., Grigg, Matthew J., Hugo, Pierre, John, Chandy C., Mayor, Alfredo, Migot-Nabias, Florence, Opoka, Robert O., Pasvol, Geoffrey, Rees, Claire, Reyburn, Hugh, Riley, Eleanor M., Shah, Binal N., Sitoe, Antonio, Sutherland, Colin J., Thuma, Philip E., Unger, Stefan A., Viwami, Firmine, Walther, Michael, Whitty, Christopher J. M., William, Timothy, Okell, Lucy C.

“… Delay in receiving treatment for uncomplicated malaria (UM) is often reported to increase the risk of developing severe malaria (SM), but access to treatment …”
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Surgery as an Adjunctive Treatment for Multidrug-Resistant Tuberculosis: An Individual Patient Data Metaanalysis von Fox, Gregory J, Mitnick, Carole D, Benedetti, Andrea, Chan, Edward D, Becerra, Mercedes, Chiang, Chen-Yuan, Keshavjee, Salmaan, Koh, Won-Jung, Shiraishi, Yuji, Viiklepp, Piret, Yim, Jae-Joon, Pasvol, Geoffrey, Robert, Jerome, Shim, Tae Sun, Shin, Sonya S, Menzies, Dick, Ahuja, S, Ashkin, D, Avendaño, M, Banerjee, R, Bauer, M, Burgos, M, Centis, R, Cobelens, F, Cox, H, D'Ambrosio, L, de Lange, W C M, DeRiemer, K, Enarson, D, Falzon, D, Flanagan, K, Flood, J, Gandhi, N, Garcia-Garcia, L, Granich, R M, Hollm-Delgado, M G, Holtz, T H, Hopewell, P, Iseman, M, Jarlsberg, L G, Kim, H R, Lancaster, J, Lange, C, Leimane, V, Leung, C C, Li, J, Menzies, D, Migliori, G B, Narita, M, Nathanson, E, Odendaal, R, O'Riordan, P, Pai, M, Palmero, D, Park, S K, Pena, J, Pérez-Guzmán, C, Ponce-de-Leon, A, Quelapio, M I D, Quy, H T, Riekstina, V, Royce, S, Salim, M, Schaaf, H S, Seung, K J, Shah, L, Shean, K, Sifuentes-Osornio, J, Sotgiu, G, Strand, M J, Sung, S W, Tabarsi, P, Tupasi, T E, Vargas, M H, van Altena, R, van der Walt, M, van der Werf, T S, Westenhouse, J, Yew, W W

“… Medical treatment for multidrug-resistant (MDR)-tuberculosis is complex, toxic, and associated with poor outcomes. Surgical lung resection may be used as an …”
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Clinical and laboratory features associated with serum phosphate concentrations in malaria and other febrile illnesses von Suen, Ho-Ming E., Pasvol, Geoffrey, Cunnington, Aubrey J.

“… Background Hypophosphatemia is common in severe infections including malaria. Previous studies suggested that serum phosphate concentrations correlate with …”
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Does α +-Thalassaemia Protect against Malaria? von Pasvol, Geoffrey

“… Pasvol discusses a new study in PLoS Medicine that shows that α +-thalassemia protects against severe but not mild malaria. A new study finds that α …”
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Group 5 drugs for multidrug-resistant tuberculosis: individual patient data meta-analysis von Fox, Greg J, Benedetti, Andrea, Cox, Helen, Koh, Won-Jung, Viiklepp, Piret, Ahuja, Shama, Pasvol, Geoffrey, Menzies, Dick

“… The role of so-called "group 5" second-line drugs as a part of antibiotic therapy for multidrug-resistant tuberculosis (MDR-TB) is widely debated. We performed …”
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Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study von Wilkinson, Robert J, Llewelyn, Martin, Toossi, Zahra, Patel, Punita, Pasvol, Geoffrey, Lalvani, Ajit, Wright, Dennis, Latif, Mohammed, Davidson, Robert N

“… Susceptibility to disease after infection by Mycobacterium tuberculosis is influenced by environmental and host genetic factors. Vitamin D metabolism leads to …”
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High levels of multidrug resistant tuberculosis in new and treatment-failure patients from the Revised National Tuberculosis Control Programme in an urban metropolis (Mumbai) in Western India von D'souza, Desiree TB, Mistry, Nerges F, Vira, Tina S, Dholakia, Yatin, Hoffner, Sven, Pasvol, Geoffrey, Nicol, Mark, Wilkinson, Robert J

“… Background India, China and Russia account for more than 62% of multidrug resistant tuberculosis (MDRTB) globally. Within India, locations like urban …”
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Likely Health Outcomes for Untreated Acute Febrile Illness in the Tropics in Decision and Economic Models; A Delphi Survey von Lubell, Yoel, Staedke, Sarah G., Greenwood, Brian M., Kamya, Moses R., Molyneux, Malcolm, Newton, Paul N., Reyburn, Hugh, Snow, Robert W., D'Alessandro, Umberto, English, Mike, Day, Nick, Kremsner, Peter, Dondorp, Arjen, Mbacham, Wilfred, Dorsey, Grant, Owusu-Agyei, Seth, Maitland, Kathryn, Krishna, Sanjeev, Newton, Charles, Pasvol, Geoffrey, Taylor, Terrie, von Seidlein, Lorenz, White, Nicholas J., Binka, Fred, Mills, Anne, Whitty, Christopher J. M.

“… Modelling is widely used to inform decisions about management of malaria and acute febrile illnesses. Most models depend on estimates of the probability that …”
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Rapid Molecular Detection of Rifampicin Resistance Facilitates Early Diagnosis and Treatment of Multi-Drug Resistant Tuberculosis: Case Control Study von O'Riordan, Philly, Schwab, Uli, Logan, Sarah, Cooke, Graham, Wilkinson, Robert J., Davidson, Robert N., Bassett, Paul, Wall, Robert, Pasvol, Geoffrey, Flanagan, Katie L.

“… Multi-drug resistant tuberculosis (MDR-TB) is a major public health concern since diagnosis is often delayed, increasing the risk of spread to the community …”
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Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria von Fivelman, Quinton L, Butcher, Geoffrey A, Adagu, Ipemida S, Warhurst, David C, Pasvol, Geoffrey

“… We report the first in vitro and genetic confirmation of Malarone (GlaxoSmithKline; atovaquone and proguanil hydrochloride) resistance in Plasmodium falciparum …”
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How many pathways for invasion of the red blood cell by the malaria parasite? von Pasvol, Geoffrey

“… Merozoites of the malaria parasite Plasmodium falciparum use several receptors for cellular engagement when they invade human red blood cells. Recently, a …”
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Indicators of Life-Threatening Malaria in African Children von Marsh, Victoria, Marsh, Kevin, Forster, Dayo, Waruiru, Catherine, Mwangi, Isiah, Winstanley, Peter, Winstanley, Maria, Newton, Charles, Warn, Peter, Peshu, Norbert, Pasvol, Geoffrey, Snow, Robert

“… Malaria remains a major cause of childhood morbidity and mortality in the tropics. The World Health Organization (WHO) has worked to define standard criteria …”
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Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil von Sutherland, Colin J, Laundy, Matt, Price, Nicholas, Burke, Martina, Fivelman, Quinton L, Pasvol, Geoffrey, Klein, John L, Chiodini, Peter L

“… Background Fixed-dose combination antimalarial drugs have played an increasingly important role in the treatment and chemoprophylaxis of falciparum malaria …”
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Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis von Lalvani, A, Brookes, R, Wilkinson, R J, Malin, A S, Pathan, A A, Andersen, P, Dockrell, H, Pasvol, G, Hill, A V

“… Protective immunity to Mycobacterium tuberculosis is poorly understood, but mounting evidence, at least in animal models, implicates major histocompatibility …”
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Frequencies of region of difference 1 antigen-specific but not purified protein derivative-specific gamma interferon-secreting T cells correlate with the presence of tuberculosis disease but do not distinguish recent from remote latent infections von Hinks, Timothy S C, Dosanjh, Davinder P S, Innes, John A, Pasvol, Geoffrey, Hackforth, Sarah, Varia, Hansa, Millington, Kerry A, Liu, Xiao-Qing, Bakir, Mustafa, Soysal, Ahmet, Davidson, Robert N, Gunatheesan, Rubamalar, Lalvani, Ajit

“… The majority of individuals infected with Mycobacterium tuberculosis achieve lifelong immune containment of the bacillus. What constitutes this effective host …”
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Evaluation of T-cell responses to novel RD1- and RD2-encoded Mycobacterium tuberculosis gene products for specific detection of human tuberculosis infection von Liu, Xiao-Qing, Dosanjh, Davinder, Varia, Hansa, Ewer, Katie, Cockle, Paul, Pasvol, Geoffrey, Lalvani, Ajit

“… The tuberculin skin test for diagnosing Mycobacterium tuberculosis infection suffers from antigenic cross-reactivity of purified protein derivative with BCG, …”
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Cluster of Falciparum Malaria Cases in UK Airport von Rodger, Alison J., Cooke, Graham S., Ord, Rosalynn, Sutherland, Colin J., Pasvol, Geoffrey

“… A cluster of 6 cases of Plasmodium falciparum malaria occurred in a UK airport among 30 travelers returning to the United States from East Africa. Molecular …”
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Reduction of chemokine secretion in response to mycobacteria in infliximab-treated patients von Newton, Sandra M, Mackie, Sarah L, Martineau, Adrian R, Wilkinson, Katalin A, Kampmann, Beate, Fisher, Corinne, Dutta, Shouma, Levin, Michael, Wilkinson, Robert J, Pasvol, Geoffrey

“… The use of anti-tumor necrosis factor (TNF) agents as a treatment for chronic inflammatory conditions has been shown to be associated with an increased risk of …”
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The R0 journey: from 1950s malaria to COVID-19 von Baum, Jake, Pasvol, Geoffrey, Carter, Richard

“… Letter to the Editor …”
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From 1950s malaria to COVID-19 von Baum, Jake, Pasvol, Geoffrey, Carter, Richard

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