Výsledky vyhľadávania - "Parks, Benjamin"
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Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia
ISSN: 1087-0156, 1546-1696, 1546-1696Vydavateľské údaje: United States Nature Publishing Group 01.12.2019Vydané v Nature biotechnology (01.12.2019)“…Identifying the causes of human diseases requires deconvolution of abnormal molecular phenotypes spanning DNA accessibility, gene expression and protein…”
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The effect of slab gaps on subduction dynamics and mantle upwelling
ISSN: 0040-1951, 1879-3266Vydavateľské údaje: Amsterdam Elsevier B.V 20.06.2020Vydané v Tectonophysics (20.06.2020)“…Gaps within a subducting plate can alter the surrounding mantle flow field and the overall subduction zone dynamics by allowing hot sub-slab mantle to flow…”
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The Signature of Metasomatized Subcontinental Lithospheric Mantle in the Basaltic Magmatism of the Payenia Volcanic Province, Argentina
ISSN: 1525-2027, 1525-2027Vydavateľské údaje: Washington John Wiley & Sons, Inc 01.01.2022Vydané v Geochemistry, geophysics, geosystems : G3 (01.01.2022)“…The Payenia region of Argentina (34.5–38°S) is a large Pliocene‐Quaternary volcanic province of basaltic compositions in the Andean Cordillera foothills…”
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Single-molecule states link transcription factor binding to gene expression
ISSN: 0028-0836, 1476-4687, 1476-4687Vydavateľské údaje: London Nature Publishing Group UK 19.12.2024Vydané v Nature (London) (19.12.2024)“…The binding of multiple transcription factors (TFs) to genomic enhancers drives gene expression in mammalian cells 1 . However, the molecular details that link…”
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A Thousand and One Thebaidian Noons: Transhumanism and Acedia
ISSN: 0018-1196, 1468-2265Vydavateľské údaje: Oxford Wiley Subscription Services, Inc 01.05.2021Vydané v Heythrop journal (01.05.2021)Získať plný text
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Microstructural Shift due to Post‐Deformation Annealing in the Upper Mantle
ISSN: 1525-2027, 1525-2027Vydavateľské údaje: Washington John Wiley & Sons, Inc 01.03.2021Vydané v Geochemistry, geophysics, geosystems : G3 (01.03.2021)“…Syntectonic microstructural evolution is a well‐known phenomenon in the mantle and lower crust associated with two main processes: grain size reduction through…”
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The standardization of clinical ethics consultation and technique’s “long encirclement” of humanity: a response to Brummett and Muaygil
ISSN: 1747-5341, 1747-5341Vydavateľské údaje: London BioMed Central 12.10.2021Vydané v Philosophy, ethics, and humanities in medicine : PEHM (12.10.2021)“…In their recent article, Brummett and Muaygil reject Bishop et al.’s framing of the debate over standardization in clinical ethics consultation (CEC) “as one…”
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The Case for Conserving Monsters: Rosemarie Garland-Thomson and the Body of Christ
ISSN: 2331-2521, 2331-253XVydavateľské údaje: Philadelphia Routledge 02.01.2020Vydané v Journal of disability & religion (02.01.2020)“…Rosemarie Garland-Thomson has made a moving case for what she calls conserving the generative resourcefulness of disability. She thinks that in showing all the…”
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NEAT-seq: simultaneous profiling of intra-nuclear proteins, chromatin accessibility and gene expression in single cells
ISSN: 1548-7091, 1548-7105, 1548-7105Vydavateľské údaje: New York Nature Publishing Group US 01.05.2022Vydané v Nature methods (01.05.2022)“…In this work, we describe NEAT-seq (sequencing of nuclear protein epitope abundance, chromatin accessibility and the transcriptome in single cells), enabling…”
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Single-molecule chromatin configurations link transcription factor binding to expression in human cells
ISSN: 2692-8205, 2692-8205Vydavateľské údaje: United States Cold Spring Harbor Laboratory Press 04.02.2024Vydané v bioRxiv (04.02.2024)“…The binding of multiple transcription factors (TFs) to genomic enhancers activates gene expression in mammalian cells. However, the molecular details that link…”
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Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19
ISSN: 1540-9538, 1540-9538Vydavateľské údaje: United States 02.08.2021Vydané v The Journal of experimental medicine (02.08.2021)“…Our understanding of protective versus pathological immune responses to SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is limited by…”
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PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape
ISSN: 1529-2908, 1529-2916, 1529-2916Vydavateľské údaje: New York Nature Publishing Group US 01.05.2024Vydané v Nature immunology (01.05.2024)“…Adaptive immunity relies on specialized effector functions elicited by lymphocytes, yet how antigen recognition activates appropriate effector responses…”
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The peridotite deformation cycle in cratons and the deep impact of subduction
ISSN: 0040-1951, 1879-3266Vydavateľské údaje: Amsterdam Elsevier B.V 20.10.2021Vydané v Tectonophysics (20.10.2021)“…Xenoliths play a crucial role in interpretation of mantle deformation and geochemistry. The classic work of Mercier and Nicolas (1975) introduced the concept…”
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Silicate melt inclusions in the new millennium: A review of recommended practices for preparation, analysis, and data presentation
ISSN: 0009-2541, 1872-6836Vydavateľské údaje: Elsevier B.V 05.06.2021Vydané v Chemical geology (05.06.2021)“…Mineral-hosted melt inclusions have become an important source of information on magmatic processes. As the number of melt inclusion studies increases, so does…”
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Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape
ISSN: 1529-2908, 1529-2916, 1529-2916Vydavateľské údaje: New York Nature Publishing Group US 01.06.2024Vydané v Nature immunology (01.06.2024)Získať plný text
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Scaling Single Cell Genomics Analysis to Millions of Cells
ISBN: 9798382626086Vydavateľské údaje: ProQuest Dissertations & Theses 01.01.2023“…Improved experimental methods in single cell genomics have increased dataset sizes by two orders of magnitude in the last five years, such that software…”
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Dissertation -
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Scalable high-performance single cell data analysis with BPCells
ISSN: 2692-8205, 2692-8205Vydavateľské údaje: United States Cold Spring Harbor Laboratory 01.04.2025Vydané v bioRxiv (01.04.2025)“…The growth of single-cell datasets to multi-million cell atlases has uncovered major scalability problems for single-cell analysis software. Here, we present…”
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Techno-Wizards and Despairing Dragons: On Magic, Chaos, and Acedia in Modern Medical Technology
ISBN: 9798664766141Vydavateľské údaje: ProQuest Dissertations & Theses 01.01.2020“…This dissertation is an attempt to do three things. First, it is an attempt to show that the modern techno-scientific project, what some such as Gerald P…”
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DFT Studies on the Effects of Functionalization on the Electronic and Optical Properties of 2,7-di-(N,N-diphenylamino)-9,9-dimethyl-9H-fluorene
ISSN: 2573-2293Vydavateľské údaje: Washington American Chemical Society 12.12.2024Vydané v ChemRxiv (12.12.2024)“…Density functional theory (DFT) calculations using B3LYP and 6-311+ G(d,p) basis set were performed to investigate the effect of functionalization on the…”
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Eighth and Fourteenth Amendment Concerns with the BoP Guidelines for Advance Directives
ISSN: 2691-4875Vydavateľské údaje: Columbia University Libraries 01.02.2020Vydané v Voices in bioethics (01.02.2020)“…The current guidelines set forth by the U.S. Department of Justice Federal Bureau of Prisons (BoP) for institutional supplements to advanced directives (AD’s)…”
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