Výsledky vyhľadávania - "Pappalardo, Morena"

Fluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas Autor Subiros-Funosas, Ramon, Ho, Vivian Cheuk Lam, Barth, Nicole D, Mendive-Tapia, Lorena, Pappalardo, Morena, Barril, Xavier, Ma, Ruoyu, Zhang, Cheng-Bin, Qian, Bin-Zhi, Sintes, Miquel, Ghashghaei, Ouldouz, Lavilla, Rodolfo, Vendrell, Marc

“…Keratin 1 (KRT1) is overexpressed in squamous carcinomas and associated with aggressive pathologies in breast cancer. Herein we report the design and…”
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Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses Autor Pappalardo, Morena, Juliá, Miguel, Howard, Mark J., Rossman, Jeremy S., Michaelis, Martin, Wass, Mark N.

“…Reston viruses are the only Ebolaviruses that are not pathogenic in humans. We analyzed 196 Ebolavirus genomes and identified specificity determining positions…”
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Investigating Ebola virus pathogenicity using molecular dynamics Autor Pappalardo, Morena, Collu, Francesca, Macpherson, James, Michaelis, Martin, Fraternali, Franca, Wass, Mark N.

“…Background Ebolaviruses have been known to cause deadly disease in humans for 40 years and have recently been demonstrated in West Africa to be able to cause…”
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VarMod: modelling the functional effects of non-synonymous variants Autor Pappalardo, M., Wass, M. N.

“…Unravelling the genotype-phenotype relationship in humans remains a challenging task in genomics studies. Recent advances in sequencing technologies mean there…”
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Changes associated with Ebola virus adaptation to novel species Autor Pappalardo, Morena, Reddin, Ian G, Cantoni, Diego, Rossman, Jeremy S, Michaelis, Martin, Wass, Mark N

“…Ebola viruses are not pathogenic but can be adapted to replicate and cause disease in rodents. Here, we used a structural bioinformatics approach to analyze…”
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Heme oxygenase-2/adiponectin protein–protein interaction in metabolic syndrome Autor Vanella, Luca, Li Volti, Giovanni, Guccione, Salvatore, Rappazzo, Giancarlo, Salvo, Eliana, Pappalardo, Morena, Forte, Stefano, Schwartzman, Michal L., Abraham, Nader G.

“…► HO-2 knockout mice present a metabolic syndrome-like phenotype. ► Inhibition of both HO-1 and HO-2 decreased adiponectin formation. ► Existence of…”
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Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors Autor Sorrenti, Valeria, Guccione, Salvatore, Di Giacomo, Claudia, Modica, Maria N., Pittalà, Valeria, Acquaviva, Rosaria, Basile, Livia, Pappalardo, Morena, Salerno, Loredana

“…Imidazole‐based compounds previously synthesized in our laboratory were selected and reconsidered as inhibitors of heme oxygenase‐1 obtained from the…”
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A Computational Study of Ebolavirus Pathogenicity and a Modeling Approach for Human Non-Synonymous Variants Autor Pappalardo, Morena

“…Recent advances in genome sequencing are improving our better understanding of genetic variation. However, the investigation of the genotype-phenotype…”
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