Search Results - "Palmieri, Fabrizio"

Update of drug-resistant tuberculosis treatment guidelines: A turning point by Vanino, Elisa, Granozzi, Bianca, Akkerman, Onno W., Munoz-Torrico, Marcela, Palmieri, Fabrizio, Seaworth, Barbara, Tiberi, Simon, Tadolini, Marina

“…•A guideline update regarding drug-resistant tuberculosis (DR-TB) treatment has been recently published by World Health Organization.•6-month bedaquiline,…”
Get full text

Coinfection of tuberculosis and COVID-19 limits the ability to in vitro respond to SARS-CoV-2 by Petrone, Linda, Petruccioli, Elisa, Vanini, Valentina, Cuzzi, Gilda, Gualano, Gina, Vittozzi, Pietro, Nicastri, Emanuele, Maffongelli, Gaetano, Grifoni, Alba, Sette, Alessandro, Ippolito, Giuseppe, Migliori, Giovanni Battista, Palmieri, Fabrizio, Goletti, Delia

“…•TB and COVID-19 coinfection does not affect M. tuberculosis-specific response.•TB and COVID-19 coinfection limits the ability to in vitro respond to…”
Get full text

Early expansion of myeloid-derived suppressor cells inhibits SARS-CoV-2 specific T-cell response and may predict fatal COVID-19 outcome by Sacchi, Alessandra, Grassi, Germana, Bordoni, Veronica, Lorenzini, Patrizia, Cimini, Eleonora, Casetti, Rita, Tartaglia, Eleonora, Marchioni, Luisa, Petrosillo, Nicola, Palmieri, Fabrizio, D’Offizi, Gianpiero, Notari, Stefania, Tempestilli, Massimo, Capobianchi, Maria Rosaria, Nicastri, Emanuele, Maeurer, Markus, Zumla, Alimuddin, Locatelli, Franco, Antinori, Andrea, Ippolito, Giuseppe, Agrati, Chiara

“…The immunological mechanisms underlying the clinical presentation of SARS-CoV-2 infection and those influencing the disease outcome remain to be defined…”
Get full text

Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases by Carsetti, Rita, Zaffina, Salvatore, Piano Mortari, Eva, Terreri, Sara, Corrente, Francesco, Capponi, Claudia, Palomba, Patrizia, Mirabella, Mattia, Cascioli, Simona, Palange, Paolo, Cuccaro, Ilaria, Milito, Cinzia, Zumla, Alimuddin, Maeurer, Markus, Camisa, Vincenzo, Vinci, Maria Rosaria, Santoro, Annapaola, Cimini, Eleonora, Marchioni, Luisa, Nicastri, Emanuele, Palmieri, Fabrizio, Agrati, Chiara, Ippolito, Giuseppe, Porzio, Ottavia, Concato, Carlo, Onetti Muda, Andrea, Raponi, Massimiliano, Quintarelli, Concetta, Quinti, Isabella, Locatelli, Franco

“…SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum of clinical expression of SARS-CoV-2 illness suggests that individual…”
Get full text

Quantitative and qualitative profiles of circulating monocytes may help identifying tuberculosis infection and disease stages by La Manna, Marco Pio, Orlando, Valentina, Dieli, Francesco, Di Carlo, Paola, Cascio, Antonio, Cuzzi, Gilda, Palmieri, Fabrizio, Goletti, Delia, Caccamo, Nadia

“…Tuberculosis (TB) is one of the most important cause of morbidity and death among infectious diseases, and continuous efforts are needed to improve diagnostic…”
Get full text

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment by Joosten, Simone A., van Meijgaarden, Krista E., del Nonno, Franca, Baiocchini, Andrea, Petrone, Linda, Vanini, Valentina, Smits, Hermelijn H., Palmieri, Fabrizio, Goletti, Delia, Ottenhoff, Tom H. M.

“…B-cells not only produce immunoglobulins and present antigens to T-cells, but also additional key roles in the immune system. Current knowledge on the role of…”
Get full text

Characterization of the immune impairment of patients with tuberculosis and COVID-19 coinfection by Najafi-Fard, Saeid, Aiello, Alessandra, Navarra, Assunta, Cuzzi, Gilda, Vanini, Valentina, Migliori, Giovanni Battista, Gualano, Gina, Cerva, Carlotta, Grifoni, Alba, Sette, Alessandro, Vaia, Francesco, Palmieri, Fabrizio, Goletti, Delia

“…•Tumor necrosis factor-α significantly discriminates tuberculosis (TB)-COVID-19 from COVID-19.•SARS-CoV-2-specific response is significantly impaired in…”
Get full text

COVID-19 disease—Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and management outcomes in survivors and non-survivors: A longitudinal descriptive cohort study by Lanini, Simone, Montaldo, Chiara, Nicastri, Emanuele, Vairo, Francesco, Agrati, Chiara, Petrosillo, Nicola, Scognamiglio, Paola, Antinori, Andrea, Puro, Vincenzo, Di Caro, Antonino, De Carli, Gabriella, Navarra, Assunta, Agresta, Alessandro, Cimaglia, Claudia, Palmieri, Fabrizio, D’Offizi, Gianpiero, Marchioni, Luisa, Kobinger, Gary Pignac, Maeurer, Markus, Girardi, Enrico, Capobianchi, Maria Rosaria, Zumla, Alimuddin, Locatelli, Franco, Ippolito, Giuseppe

“…Detailed temporal analyses of complete (full) blood count (CBC) parameters, their evolution and relationship to patient age, gender, co-morbidities and…”
Get full text

In-vitro evaluation of the immunomodulatory effects of Baricitinib: Implication for COVID-19 therapy by Petrone, Linda, Petruccioli, Elisa, Alonzi, Tonino, Vanini, Valentina, Cuzzi, Gilda, Najafi Fard, Saeid, Castilletti, Concetta, Palmieri, Fabrizio, Gualano, Gina, Vittozzi, Pietro, Nicastri, Emanuele, Lepore, Luciana, Grifoni, Alba, Antinori, Andrea, Vergori, Alessandra, Ippolito, Giuseppe, Cantini, Fabrizio, Goletti, Delia

“…•Baricitinib has been suggested as a promising therapy for COVID-19.•Baricitinib modulates in vitro SARS-CoV-2-specific-response in a whole blood…”
Get full text

Evaluation of IP-10 in Quantiferon-Plus as biomarker for the diagnosis of latent tuberculosis infection by Petrone, Linda, Vanini, Valentina, Chiacchio, Teresa, Petruccioli, Elisa, Cuzzi, Gilda, Schininà, Vincenzo, Palmieri, Fabrizio, Ippolito, Giuseppe, Goletti, Delia

“…The QuantiFERON-TB Gold Plus (QFT-Plus) is a new test for latent tuberculosis infection (LTBI) diagnosis, in which has been added a new tube containing shorter…”
Get full text

National Institute for the Infectious Diseases “L. Spallanzani” IRCCS. Recommendations for COVID-19 Clinical Management by Nicastri, Emanuele, Petrosillo, Nicola, Ascoli Bartoli, Tommaso, Lepore, Luciana, Mondi, Annalisa, Palmieri, Fabrizio, D’Offizi, Gianpiero, Marchioni, Luisa, Murachelli, Silvia, Ippolito, Giuseppe, Antinori for ICOTREG, Andrea

“…On January 9th, 2020, the “World Health Organization” (WHO) declared the identification, by Chinese Health authorities, of a novel coronavirus, further…”
Get full text

Detection of Mycobacterium tuberculosis DNA in CD34+ peripheral blood mononuclear cells of adults with tuberculosis infection and disease by Repele, Federica, Alonzi, Tonino, Navarra, Assunta, Farroni, Chiara, Salmi, Andrea, Cuzzi, Gilda, Delogu, Giovanni, Gualano, Gina, Puro, Vincenzo, De Carli, Gabriella, Girardi, Enrico, Palmieri, Fabrizio, Martineau, Adrian R., Goletti, Delia

“…•Mycobacterium tuberculosis (Mtb) DNA is detected in the peripheral blood cells of donors with tuberculosis (TB) or TB infection.•Mtb DNA is detected in the…”
Get full text

3-Gene-TB-SCORE Accuracy for Tuberculosis Disease Diagnosis Is Not Affected by Immune-Mediated Inflammatory Disease Comorbidity by Petruccioli, Elisa, Alonzi, Tonino, Navarra, Assunta, Altera, Anna Maria Gerarda, Cuzzi, Gilda, Farroni, Chiara, Repele, Federica, Gualano, Gina, Lindestam Arlehamn, Cecilia S., Palmieri, Fabrizio, Salmi, Andrea, Vanini, Valentina, Goletti, Delia

“…Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a major global health threat. Approximately one-quarter of the world’s population has an…”
Get full text

New Antituberculosis Drugs: From Clinical Trial to Programmatic Use by Gualano, Gina, CAPONE, Susanna, MATTEELLI, Alberto, Palmieri, Fabrizio

“…Treatment of multidrug-resistant tuberculosis (MDR-TB) cases is challenging because it relies on second-line drugs that are less potent and more toxic than…”
Get full text

Clinical outcomes and adverse events of nontuberculous mycobacterial lung disease treated at an Italian tertiary referral center by Carli, Serena Maria, Mencarini, Paola, Licata, Maria Angela Vittoria, Musso, Maria, Cerva, Carlotta, Mastrobattista, Annelisa, Vittozzi, Pietro, Mosti, Silvia, Nisii, Carla, Mazzarelli, Antonio, Navarra, Assunta, De Carli, Gabriella, Ianniello, Stefania, Palmieri, Fabrizio, Gualano, Gina

“…Treatment of NTM lung disease (NTM-LD) is based on combinations of antimycobacterial drugs. It lasts 12 months if respiratory samples become culture negative,…”
Get full text

ERS/ECDC Statement: European Union standards for tuberculosis care, 2017 update by Migliori, Giovanni Battista, Sotgiu, Giovanni, Rosales-Klintz, Senia, Centis, Rosella, D'Ambrosio, Lia, Abubakar, Ibrahim, Bothamley, Graham, Caminero, Jose Antonio, Cirillo, Daniela Maria, Dara, Masoud, de Vries, Gerard, Aliberti, Stefano, Dinh-Xuan, Anh Tuan, Duarte, Raquel, Midulla, Fabio, Solovic, Ivan, Subotic, Dragan R, Amicosante, Massimo, Correia, Ana Maria, Cirule, Andra, Gualano, Gina, Kunst, Heinke, Palmieri, Fabrizio, Riekstina, Vija, Tiberi, Simon, Verduin, Remi, van der Werf, Marieke J

“…The International Standards for Tuberculosis Care define the essential level of care for managing patients who have or are presumed to have tuberculosis, or…”
Get more information

Putting in harm to cure: Drug related adverse events do not affect outcome of patients receiving treatment for multidrug-resistant Tuberculosis. Experience from a tertiary hospital in Italy by Gualano, Gina, Mencarini, Paola, Musso, Maria, Mosti, Silvia, Santangelo, Laura, Murachelli, Silvia, Cannas, Angela, Di Caro, Antonino, Navarra, Assunta, Goletti, Delia, Girardi, Enrico, Palmieri, Fabrizio

“…Treatment of multi-drug resistant Tuberculosis (MDR-TB) is challenging because it mostly relies on drugs with lower efficacy and greater toxicity than those…”
Get full text

Tuberculin skin test – Outdated or still useful for Latent TB infection screening? by Gualano, Gina, Mencarini, Paola, Lauria, Francesco Nicola, Palmieri, Fabrizio, Mfinanga, Sayoki, Mwaba, Peter, Chakaya, Jeremiah, Zumla, Alimuddin, Ippolito, Giuseppe

“…•Tuberculin skin test (TST) is over a century old but it continues to be used widely.•When IGRAs were introduced it was anticipated that they would rapidly…”
Get full text

Exploratory analysis to identify the best antigen and the best immune biomarkers to study SARS-CoV-2 infection by Petruccioli, Elisa, Najafi Fard, Saeid, Navarra, Assunta, Petrone, Linda, Vanini, Valentina, Cuzzi, Gilda, Gualano, Gina, Pierelli, Luca, Bertoletti, Antonio, Nicastri, Emanuele, Palmieri, Fabrizio, Ippolito, Giuseppe, Goletti, Delia

“…Background Recent studies proposed the whole-blood based IFN-γ-release assay to study the antigen-specific SARS-CoV-2 response. Since the early prediction of…”
Get full text

Accuracy of QuantiFERON SARS-CoV-2 research use only assay and characterization of the CD4+ and CD8+ T cell-SARS-CoV-2 response: comparison with a homemade interferon-γ release assay by Aiello, Alessandra, Coppola, Andrea, Vanini, Valentina, Petrone, Linda, Cuzzi, Gilda, Salmi, Andrea, Altera, Anna Maria Gerarda, Tortorella, Carla, Gualano, Gina, Gasperini, Claudio, Scolieri, Palma, Beccacece, Alessia, Vita, Serena, Bruzzese, Vincenzo, Lorenzetti, Roberto, Palmieri, Fabrizio, Nicastri, Emanuele, Goletti, Delia

“…•The QuantiFERON SARS-CoV-2 research use only assay response is mediated by CD4+ and CD8+ T cells.•Immune response to the antigen (Ag)2 tube is more accurate…”
Get full text