Suchergebnisse - "Pagano, Allan F."
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Early skeletal muscle deconditioning and reduced exercise capacity during (neo)adjuvant chemotherapy in patients with breast cancer
ISSN: 0008-543X, 1097-0142, 1097-0142Veröffentlicht: United States Wiley Subscription Services, Inc 15.01.2023Veröffentlicht in Cancer (15.01.2023)“… Background Fatigue is a hallmark of breast cancer and is associated with skeletal muscle deconditioning. If cancer‐related fatigue occurs early during …”
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Early structural and functional signature of 3‐day human skeletal muscle disuse using the dry immersion model
ISSN: 0022-3751, 1469-7793, 1469-7793Veröffentlicht: England Wiley Subscription Services, Inc 01.07.2017Veröffentlicht in The Journal of physiology (01.07.2017)“… Key points Our study contributes to the characterization of muscle loss and weakness processes induced by a sedentary life style, chronic hypoactivity, …”
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Short‐term disuse promotes fatty acid infiltration into skeletal muscle
ISSN: 2190-5991, 2190-6009, 2190-6009Veröffentlicht: Germany John Wiley & Sons, Inc 01.04.2018Veröffentlicht in Journal of cachexia, sarcopenia and muscle (01.04.2018)“… Background Many physiological and/or pathological conditions lead to muscle deconditioning, a well‐described phenomenon characterized by a loss of strength and …”
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Skeletal Muscle Deconditioning in Breast Cancer Patients Undergoing Chemotherapy: Current Knowledge and Insights From Other Cancers
ISSN: 2296-634X, 2296-634XVeröffentlicht: Frontiers Media S.A 14.09.2021Veröffentlicht in Frontiers in cell and developmental biology (14.09.2021)“… Breast cancer represents the most commonly diagnosed cancer while neoadjuvant and adjuvant chemotherapies are extensively used in order to reduce tumor …”
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Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable
ISSN: 0021-972X, 1945-7197, 1945-7197Veröffentlicht: Washington, DC Endocrine Society 01.05.2018Veröffentlicht in The journal of clinical endocrinology and metabolism (01.05.2018)“… Abstract Context The effects of energy-balanced bed rest on metabolic flexibility have not been thoroughly examined. Objective We investigated the effects of …”
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The role of AMP-activated protein kinase in the coordination of skeletal muscle turnover and energy homeostasis
ISSN: 1522-1563, 1522-1563Veröffentlicht: United States 01.09.2012Veröffentlicht in American Journal of Physiology: Cell Physiology (01.09.2012)“… The AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that acts as a sensor of cellular energy status switch regulating several systems …”
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Evaluation of an Antioxidant and Anti-inflammatory Cocktail Against Human Hypoactivity-Induced Skeletal Muscle Deconditioning
ISSN: 1664-042X, 1664-042XVeröffentlicht: Switzerland Frontiers 12.02.2020Veröffentlicht in Frontiers in physiology (12.02.2020)“… Understanding the molecular pathways involved in the loss of skeletal muscle mass and function induced by muscle disuse is a crucial issue in the context of …”
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Muscle Resting and TGF-β Inhibitor Treatment Prevent Fatty Infiltration Following Skeletal Muscle Injury
ISSN: 1015-8987, 1421-9778, 1421-9778Veröffentlicht: Germany Karger 2019Veröffentlicht in Cellular physiology and biochemistry (2019)“… Skeletal muscle injuries are the most common type of injury occurring in sports, and investigating skeletal muscle regeneration as well as understanding the …”
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Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients
ISSN: 2190-5991, 2190-6009, 2190-6009Veröffentlicht: Germany John Wiley & Sons, Inc 01.06.2022Veröffentlicht in Journal of cachexia, sarcopenia and muscle (01.06.2022)“… Background Chemotherapy is extensively used to treat breast cancer and is associated with skeletal muscle deconditioning, which is known to reduce patients' …”
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Muscle Regeneration with Intermuscular Adipose Tissue (IMAT) Accumulation Is Modulated by Mechanical Constraints
ISSN: 1932-6203, 1932-6203Veröffentlicht: United States Public Library of Science 02.12.2015Veröffentlicht in PloS one (02.12.2015)“… Sports trauma are able to induce muscle injury with fibrosis and accumulation of intermuscular adipose tissue (IMAT), which affect muscle function. This study …”
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Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress
ISSN: 1741-7007, 1741-7007Veröffentlicht: London BioMed Central 12.06.2018Veröffentlicht in BMC biology (12.06.2018)“… Background Skeletal muscle atrophy is a common feature of numerous chronic pathologies and is correlated with patient mortality. The REDD1 protein is currently …”
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A single chemotherapy administration induces muscle atrophy, mitochondrial alterations and apoptosis in breast cancer patients
ISSN: 2190-5991, 2190-6009, 2190-6009Veröffentlicht: Germany John Wiley & Sons, Inc 01.02.2024Veröffentlicht in Journal of cachexia, sarcopenia and muscle (01.02.2024)“… Background Breast cancer patients are commonly treated with sequential administrations of epirubicin–cyclophosphamide (EC) and paclitaxel (TAX). The chronic …”
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Hypercaloric low-carbohydrate high-fat diet protects against the development of nonalcoholic fatty liver disease in obese mice in contrast to isocaloric Western diet
ISSN: 2296-861X, 2296-861XVeröffentlicht: Switzerland Frontiers Media S.A 20.03.2024Veröffentlicht in Frontiers in nutrition (Lausanne) (20.03.2024)“… Obesity and metabolic complications, such as type 2 diabetes and nonalcoholic fatty liver disease (NAFLD), are one of the greatest public health challenges of …”
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Evolution of Physical Status From Diagnosis to the End of First-Line Treatment in Breast, Lung, and Colorectal Cancer Patients: The PROTECT-01 Cohort Study Protocol
ISSN: 2234-943X, 2234-943XVeröffentlicht: Frontiers Media S.A 07.08.2020Veröffentlicht in Frontiers in oncology (07.08.2020)“… Background: Cancer cachexia and exacerbated fatigue represent two hallmarks in cancer patients, negatively impacting their exercise tolerance and ultimately …”
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Muscle wasting and aging: Experimental models, fatty infiltrations, and prevention
ISSN: 0098-2997, 1872-9452Veröffentlicht: England Elsevier Ltd 01.08.2016Veröffentlicht in Molecular aspects of medicine (01.08.2016)“… Identification of cost-effective interventions to maintain muscle mass, muscle strength, and physical performance during muscle wasting and aging is an …”
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The exerkine apelin reverses age-associated sarcopenia
ISSN: 1078-8956, 1546-170X, 1546-170X, 1744-7933Veröffentlicht: New York Nature Publishing Group US 01.09.2018Veröffentlicht in Nature Medicine (01.09.2018)“… Sarcopenia, the degenerative loss of skeletal muscle mass, quality and strength, lacks early diagnostic tools and new therapeutic strategies to prevent the …”
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Tracking cancer‐related fatigue during chemotherapy: Insights from a comparative cohort study of early breast cancer patients
ISSN: 0020-7136, 1097-0215, 1097-0215Veröffentlicht: Hoboken, USA John Wiley & Sons, Inc 15.10.2025Veröffentlicht in International journal of cancer (15.10.2025)“… Cancer‐related fatigue (CRF) is a multifactorial symptom commonly experienced by breast cancer patients treated with chemotherapy (CT) that impairs quality of …”
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Development of skeletal muscle atrophy and intermuscular adipose tissue in patients with early breast cancer treated with chemotherapy
ISSN: 1522-1563, 1522-1563Veröffentlicht: United States 01.10.2022Veröffentlicht in American Journal of Physiology: Cell Physiology (01.10.2022)“… Chemotherapy is a common therapy to treat patients with breast cancer but also leads to skeletal muscle deconditioning. Skeletal muscle deconditioning is …”
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Exacerbated central fatigue and reduced exercise capacity in early-stage breast cancer patients treated with chemotherapy
ISSN: 1439-6319, 1439-6327, 1439-6327Veröffentlicht: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2023Veröffentlicht in European journal of applied physiology (01.07.2023)“… Purpose The present study aimed to characterize the etiology of exercise-induced neuromuscular fatigue and its consequences on the force-duration relationship …”
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Impact of Eccentric versus Concentric Cycling Exercise on Neuromuscular Fatigue and Muscle Damage in Breast Cancer Patients
ISSN: 1530-0315, 1530-0315Veröffentlicht: United States 01.11.2024Veröffentlicht in Medicine and science in sports and exercise (01.11.2024)“… This study investigated the magnitude and etiology of neuromuscular fatigue and muscle damage induced by eccentric cycling compared with conventional …”
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