Výsledky vyhledávání - "Oligonucleotide Array Sequence Analysis/statistics & numerical data"

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use Autor Jiang, Yu, Hughey, Jordan M., Zhan, Xiaowei, Gong, Jian, Batini, Chiara, Liu, MengZhen, Surendran, Praveen, Young, Robin, Nielsen, Sune Fallgaard, Kontto, Jukka, Perola, Markus, Caslake, Muriel, Reily, Dermot F., Vogt, Thomas, Sattar, Naveed, Ford, Ian, Alam, Dewan S., Majumder, Abdulla al Shafi, Di Angelantonio, Emanuele, Chowdhury, Rajiv, Arveiler, Dominique, Blankenberg, Stefan, Veronesi, Giovanni, EPIC-CVD Consortium, Frossard, Philippe, Nordestgaard, Børge Grønne, Saleheen, Danish, Danesh, John, Butterworth, Adam S., Warren, Helen R., Tragante, Vinicius, Altmaier, Elisabeth, Luan, Jian’an, Scott, Robert A., Stirrups, Kathleen, Marouli, Eirini, Karpe, Fredrik, Poulter, Neil, Rolandsson, Olov, Chambers, John C., Kooner, Jaspal S., Wareham, Nicholas J., Renström, Frida, Hallmans, Göran, Marioni, Riccardo E., Corley, Janie, Starr, John M., van der Meer, Peter, Yavas, Ersin, Vaartjes, Ilonca, Asselbergs, Folkert W., Grabe, Hans J., Nauck, Matthias, Pharoah, Paul D.P., Dunning, Alison M., Dennis, Joe G., Tyrrell, Jessica, Mihailov, Evelin, Metspalu, Andres, Palmer, Colin N.A., Hall, Ian P., Strachan, David P., Understanding Society Scientific Group, Munroe, Patricia B., Jansson, Jan-Håkan, Franks, Paul W., Deloukas, Panos, Chou, Yi-Ling, Faul, Jessica D., Hammerschlag, Anke R., Hsu, Chris, Lai, Dongbing, Le, Nhung, Loukola, Anu, Mangino, Massimo, Melbourne, Carl A., Pistis, Giorgio, Qaiser, Beenish, Stringham, Heather, Wetherill, Leah, Bierut, Laura, Chen, Chu, Eaton, Charles B., Iacono, William G., Polderman, Tinca J., Schlessinger, David, Scholte, H. Steven, Smith, Jennifer A., Boehnke, Michael, Cucca, Francesco, David, Sean P., Foroud, Tatiana, Kardia, Sharon L.R., Madden, Pamela, McGue, Matt, Posthuma, Danielle, Spector, Timothy, Stram, Daniel, Kaprio, Jaakko, Vrieze, Scott

“…Smoking and alcohol use have been associated with common genetic variants in multiple loci. Rare variants within these loci hold promise in the identification…”
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From ArrayExpress to BioStudies Autor Sarkans, Ugis, Füllgrabe, Anja, Ali, Ahmed, Athar, Awais, Behrangi, Ehsan, Diaz, Nestor, Fexova, Silvie, George, Nancy, Iqbal, Haider, Kurri, Sandeep, Munoz, Jhoan, Rada, Juan, Papatheodorou, Irene, Brazma, Alvis

“…Abstract ArrayExpress (https://www.ebi.ac.uk/arrayexpress) is an archive of functional genomics data at EMBL-EBI, established in 2002, initially as an archive…”
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Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder Autor Tammimies, Kristiina, Marshall, Christian R, Walker, Susan, Kaur, Gaganjot, Thiruvahindrapuram, Bhooma, Lionel, Anath C, Yuen, Ryan K C, Uddin, Mohammed, Roberts, Wendy, Weksberg, Rosanna, Woodbury-Smith, Marc, Zwaigenbaum, Lonnie, Anagnostou, Evdokia, Wang, Zhuozhi, Wei, John, Howe, Jennifer L, Gazzellone, Matthew J, Lau, Lynette, Sung, Wilson W L, Whitten, Kathy, Vardy, Cathy, Crosbie, Victoria, Tsang, Brian, D'Abate, Lia, Tong, Winnie W L, Luscombe, Sandra, Doyle, Tyna, Carter, Melissa T, Szatmari, Peter, Stuckless, Susan, Merico, Daniele, Stavropoulos, Dimitri J, Scherer, Stephen W, Fernandez, Bridget A

“…The use of genome-wide tests to provide molecular diagnosis for individuals with autism spectrum disorder (ASD) requires more study. To perform chromosomal…”
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Microarray is an efficient tool for circRNA profiling Autor Li, Shasha, Teng, Shuaishuai, Xu, Junquan, Su, Guannan, Zhang, Yu, Zhao, Jianqing, Zhang, Suwei, Wang, Haiyan, Qin, Wenyan, Lu, Zhi John, Guo, Yong, Zhu, Qianyong, Wang, Dong

“…Abstract Circular RNAs (circRNAs) are emerging as a new class of endogenous and regulatory noncoding RNAs in latest years. With the widespread application of…”
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DNA methylation arrays as surrogate measures of cell mixture distribution Autor Houseman, Eugene Andres, Accomando, William P, Koestler, Devin C, Christensen, Brock C, Marsit, Carmen J, Nelson, Heather H, Wiencke, John K, Kelsey, Karl T

“…Background There has been a long-standing need in biomedical research for a method that quantifies the normally mixed composition of leukocytes beyond what is…”
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Tackling the widespread and critical impact of batch effects in high-throughput data Autor Leek, Jeffrey T., Scharpf, Robert B., Bravo, Héctor Corrada, Simcha, David, Langmead, Benjamin, Johnson, W. Evan, Geman, Donald, Baggerly, Keith, Irizarry, Rafael A.

“…Batch effects can lead to incorrect biological conclusions but are not widely considered. The authors show that batch effects are relevant to a range of…”
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Reuse of public genome-wide gene expression data Autor Rung, Johan, Brazma, Alvis

“…Key Points Over the past decade, high-throughput gene expression experiments have generated data from millions of assays. Data sets linked to publications are…”
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A hybrid gene selection approach for microarray data classification using cellular learning automata and ant colony optimization Autor Vafaee Sharbaf, Fatemeh, Mosafer, Sara, Moattar, Mohammad Hossein

“…This paper proposes an approach for gene selection in microarray data. The proposed approach consists of a primary filter approach using Fisher criterion which…”
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An evaluation and replication of miRNAs with disease stage and colorectal cancer‐specific mortality Autor Slattery, Martha L., Herrick, Jennifer S., Mullany, Lila E., Valeri, Nicola, Stevens, John, Caan, Bette J., Samowitz, Wade, Wolff, Roger K.

“…MicroRNAs (miRNAs) have been implicated in colorectal cancer (CRC) development and associated with prognostic indicators such as disease stage and survival…”
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An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer Autor Gatza, Michael L, Silva, Grace O, Parker, Joel S, Fan, Cheng, Perou, Charles M

“…Charles Perou and colleagues apply a panel of 52 published gene expression signatures of human breast tumors to expression data from The Cancer Genome Project…”
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Removing technical variability in RNA-seq data using conditional quantile normalization Autor Hansen, Kasper D, Irizarry, Rafael A, Wu, Zhijin

“…The ability to measure gene expression on a genome-wide scale is one of the most promising accomplishments in molecular biology. Microarrays, the technology…”
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Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression Autor Git, Anna, Dvinge, Heidi, Salmon-Divon, Mali, Osborne, Michelle, Kutter, Claudia, Hadfield, James, Bertone, Paul, Caldas, Carlos

“…RNA abundance and DNA copy number are routinely measured in high-throughput using microarray and next-generation sequencing (NGS) technologies, and the…”
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A Conserved Core of Programmed Cell Death Indicator Genes Discriminates Developmentally and Environmentally Induced Programmed Cell Death in Plants Autor Olvera-Carrillo, Yadira, Van Bel, Michiel, Van Hautegem, Tom, Fendrych, Matyáš, Huysmans, Marlies, Simaskova, Maria, van Durme, Matthias, Buscaill, Pierre, Rivas, Susana, Coll, Nuria S., Coppens, Frederik, Maere, Steven, Nowack, Moritz K.

“…A plethora of diverse programmed cell death (PCD) processes has been described in living organisms. In animals and plants, different forms of PCD play crucial…”
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A comprehensive overview of Infinium HumanMethylation450 data processing Autor Dedeurwaerder, S., Defrance, M., Bizet, M., Calonne, E., Bontempi, G., Fuks, F.

“…Infinium HumanMethylation450 beadarray is a popular technology to explore DNA methylomes in health and disease, and there is a current explosion in the use of…”
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Centering, scaling, and transformations: improving the biological information content of metabolomics data Autor van den Berg, Robert A, Hoefsloot, Huub CJ, Westerhuis, Johan A, Smilde, Age K, van der Werf, Mariët J

“…Extracting relevant biological information from large data sets is a major challenge in functional genomics research. Different aspects of the data hamper…”
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Unlocking the potential of publicly available microarray data using inSilicoDb and inSilicoMerging R/Bioconductor packages Autor Taminau, Jonatan, Meganck, Stijn, Lazar, Cosmin, Steenhoff, David, Coletta, Alain, Molter, Colin, Duque, Robin, Schaetzen, Virginie de, Weiss Solís, David Y, Bersini, Hugues, Nowé, Ann

“…Background With an abundant amount of microarray gene expression data sets available through public repositories, new possibilities lie in combining multiple…”
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The molecular classification of multiple myeloma Autor Zhan, Fenghuang, Huang, Yongsheng, Colla, Simona, Stewart, James P, Hanamura, Ichiro, Gupta, Sushil, Epstein, Joshua, Yaccoby, Shmuel, Sawyer, Jeffrey, Burington, Bart, Anaissie, Elias, Hollmig, Klaus, Pineda-Roman, Mauricio, Tricot, Guido, van Rhee, Frits, Walker, Ronald, Zangari, Maurizio, Crowley, John, Barlogie, Bart, Shaughnessy, Jr, John D

“…To better define the molecular basis of multiple myeloma (MM), we performed unsupervised hierarchic clustering of mRNA expression profiles in CD138-enriched…”
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Co-expression tools for plant biology: opportunities for hypothesis generation and caveats Autor USADEL, BJÖRN, OBAYASHI, TAKESHI, MUTWIL, MAREK, GIORGI, FEDERICO M, BASSEL, GEORGE W, TANIMOTO, MIMI, CHOW, AMANDA, STEINHAUSER, DIRK, PERSSON, STAFFAN, PROVART, NICHOLAS J

“…Gene co-expression analysis has emerged in the past 5 years as a powerful tool for gene function prediction. In essence, co-expression analysis asks the…”
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Integration of machine learning and meta-analysis identifies the transcriptomic bio-signature of mastitis disease in cattle Autor Sharifi, Somayeh, Pakdel, Abbas, Ebrahimi, Mansour, Reecy, James M., Fazeli Farsani, Samaneh, Ebrahimie, Esmaeil

“…Gram-negative bacteria such as Escherichia coli (E. coli) are assumed to be among the main agents that cause severe mastitis disease with clinical signs in…”
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Assessing the prevalence of mycoplasma contamination in cell culture via a survey of NCBI's RNA-seq archive Autor Olarerin-George, Anthony O., Hogenesch, John B.

“…Mycoplasmas are notorious contaminants of cell culture and can have profound effects on host cell biology by depriving cells of nutrients and inducing global…”
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