Výsledky vyhľadávania - "Oligonucleotide Array Sequence Analysis"

Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array Autor McEwen, Lisa M, Jones, Meaghan J, Lin, David Tse Shen, Edgar, Rachel D, Husquin, Lucas T, MacIsaac, Julia L, Ramadori, Katia E, Morin, Alexander M, Rider, Christopher F, Carlsten, Chris, Quintana-Murci, Lluís, Horvath, Steve, Kobor, Michael S

“…Background The capacity of technologies measuring DNA methylation (DNAm) is rapidly evolving, as are the options for applicable bioinformatics methods. The…”
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ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip Autor Xu, Zongli, Niu, Liang, Li, Leping, Taylor, Jack A.

“…The Illumina HumanMethylation450 BeadChip is increasingly utilized in epigenome-wide association studies, however, this array-based measurement of DNA methylation is subject to measurement variation…”
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A single-sample microarray normalization method to facilitate personalized-medicine workflows Autor Piccolo, Stephen R., Sun, Ying, Campbell, Joshua D., Lenburg, Marc E., Bild, Andrea H., Johnson, W. Evan

“…Gene-expression microarrays allow researchers to characterize biological phenomena in a high-throughput fashion but are subject to technological biases and inevitable variabilities that arise…”
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The additional values of microarray allergen assay in the management of polysensitized patients with respiratory allergy Autor Passalacqua, G., Melioli, G., Bonifazi, F., Bonini, S., Maggi, E., Senna, G., Triggiani, M., Nettis, E., Rossi, R. E., Vacca, A., Canonica, G. W.

“…, but their value in term of additional information and economic saving has not been yet defined. Objective We assessed the additional diagnostic information provided by an allergen microarray in a large population of polysensitized subjects…”
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Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort Autor Kvale, Mark N, Hesselson, Stephanie, Hoffmann, Thomas J, Cao, Yang, Chan, David, Connell, Sheryl, Croen, Lisa A, Dispensa, Brad P, Eshragh, Jasmin, Finn, Andrea, Gollub, Jeremy, Iribarren, Carlos, Jorgenson, Eric, Kushi, Lawrence H, Lao, Richard, Lu, Yontao, Ludwig, Dana, Mathauda, Gurpreet K, McGuire, William B, Mei, Gangwu, Miles, Sunita, Mittman, Michael, Patil, Mohini, Quesenberry, Charles P, Ranatunga, Dilrini, Rowell, Sarah, Sadler, Marianne, Sakoda, Lori C, Shapero, Michael, Shen, Ling, Shenoy, Tanu, Smethurst, David, Somkin, Carol P, Van Den Eeden, Stephen K, Walter, Lawrence, Wan, Eunice, Webster, Teresa, Whitmer, Rachel A, Wong, Simon, Zau, Chia, Zhan, Yiping, Schaefer, Catherine, Kwok, Pui-Yan, Risch, Neil

“…—San Francisco, undertook genome-wide genotyping of >100,000 subjects that constitute the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort…”
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Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures Autor Nakaya, Helder I, Hagan, Thomas, Duraisingham, Sai S, Lee, Eva K, Kwissa, Marcin, Rouphael, Nadine, Frasca, Daniela, Gersten, Merril, Mehta, Aneesh K, Gaujoux, Renaud, Li, Gui-Mei, Gupta, Shakti, Ahmed, Rafi, Mulligan, Mark J, Shen-Orr, Shai, Blomberg, Bonnie B, Subramaniam, Shankar, Pulendran, Bali

“… We applied systems approaches to study immune responses in young, elderly, and diabetic subjects vaccinated with the seasonal influenza vaccine across five consecutive seasons…”
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BAL Cell Gene Expression Is Indicative of Outcome and Airway Basal Cell Involvement in Idiopathic Pulmonary Fibrosis Autor Prasse, Antje, Binder, Harald, Schupp, Jonas C., Kayser, Gian, Bargagli, Elena, Jaeger, Benedikt, Hess, Moritz, Rittinghausen, Susanne, Vuga, Louis, Lynn, Heather, Violette, Shelia, Jung, Birgit, Quast, Karsten, Vanaudenaerde, Bart, Xu, Yan, Hohlfeld, Jens M., Krug, Norbert, Herazo-Maya, Jose D., Rottoli, Paola, Wuyts, Wim A., Kaminski, Naftali

“…) including 212 patients. BAL cells from 20 healthy volunteers, 26 patients with sarcoidosis stage III and IV, and 29 patients with chronic obstructive pulmonary disease were used as control subjects…”
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A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer Autor Lai, Xianyin, Wang, Mu, McElyea, Samantha Deitz, Sherman, Stuart, House, Michael, Korc, Murray

“…) and microRNA levels in normal control subjects and in patients with PDAC and CP. We report that exosomal GPC1 is not diagnostic for PDAC, whereas high exosomal levels of microRNA-10b, (miR-10b…”
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Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation Autor Cotton, Allison M, Price, E Magda, Jones, Meaghan J, Balaton, Bradley P, Kobor, Michael S, Brown, Carolyn J

“… There was high concordance of inactivation status across tissues, with 62% of TSSs subject to XCI in all 27 tissues examined, whereas 9…”
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Human intestinal microbiota composition is associated with local and systemic inflammation in obesity Autor Verdam, Froukje J., Fuentes, Susana, de Jonge, Charlotte, Zoetendal, Erwin G., Erbil, Runi, Greve, Jan Willem, Buurman, Wim A., de Vos, Willem M., Rensen, Sander S.

“… The relationship between microbiota composition, intestinal permeability, and inflammation in nonobese and obese subjects was investigated…”
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Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landraces and cultivars Autor Cavanagh, Colin R, Chao, Shiaoman, Wang, Shichen, Huang, Bevan Emma, Stephen, Stuart, Kiani, Seifollah, Forrest, Kerrie, Saintenac, Cyrille, Brown-Guedira, Gina L, Akhunova, Alina, See, Deven, Bai, Guihua, Pumphrey, Michael, Tomar, Luxmi, Wong, Debbie, Kong, Stephan, Reynolds, Matthew, da Silva, Marta Lopez, Bockelman, Harold, Talbert, Luther, Anderson, James A, Dreisigacker, Susanne, Baenziger, Stephen, Carter, Arron, Korzun, Viktor, Morrell, Peter Laurent, Dubcovsky, Jorge, Morell, Matthew K, Sorrells, Mark E, Hayden, Matthew J, Akhunov, Eduard

“… To detect regions of the wheat genome subject to selection during improvement, we developed a high-throughput array to interrogate 9,000 gene-associated single-nucleotide polymorphisms (SNP…”
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Noninvasive in vivo monitoring of tissue-specific global gene expression in humans Autor Koh, Winston, Pan, Wenying, Gawad, Charles, Fan, H Christina, Kerchner, Geoffrey A, Wyss-Coray, Tony, Blumenfeld, Yair J, El-Sayed, Yasser Y, Quake, Stephen R

“… We used high-throughput methods of RNA analysis such as microarrays and next-generation sequencing to characterize the global landscape circulating RNA in a cohort of human subjects…”
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Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis Autor Komatsu, Noriko, Okamoto, Kazuo, Sawa, Shinichiro, Nakashima, Tomoki, Oh-hora, Masatsugu, Kodama, Tatsuhiko, Tanaka, Sakae, Bluestone, Jeffrey A, Takayanagi, Hiroshi

“…Regulatory T (T reg ) cells exhibit substantial phenotypic and functional plasticity. Hiroshi Takayanagi and his colleagues report that in autoimmune…”
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Statistical implications of pooling RNA samples for microarray experiments Autor Peng, Xuejun, Wood, Constance L, Blalock, Eric M, Chen, Kuey Chu, Landfield, Philip W, Stromberg, Arnold J

“… Biologists often pool RNA samples extracted from different subjects onto a single microarray chip to help defray the cost of microarray experiments as well as to correct for the technical difficulty…”
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Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease Autor Clarke, Robert, Peden, John F, Hopewell, Jemma C, Kyriakou, Theodosios, Goel, Anuj, Heath, Simon C, Parish, Sarah, Barlera, Simona, Franzosi, Maria Grazia, Rust, Stephan, Bennett, Derrick, Silveira, Angela, Malarstig, Anders, Green, Fiona R, Lathrop, Mark, Gigante, Bruna, Leander, Karin, de Faire, Ulf, Seedorf, Udo, Hamsten, Anders, Collins, Rory, Watkins, Hugh, Farrall, Martin

“…Using a novel gene chip, investigators identified single-nucleotide polymorphisms (SNPs) from three chromosomal regions, including the LPA locus, that were…”
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Gene Expression in Relation to Exhaled Nitric Oxide Identifies Novel Asthma Phenotypes with Unique Biomolecular Pathways Autor Modena, Brian D., Tedrow, John R., Milosevic, Jadranka, Bleecker, Eugene R., Meyers, Deborah A., Wu, Wei, Bar-Joseph, Ziv, Erzurum, Serpil C., Gaston, Benjamin M., Busse, William W., Jarjour, Nizar N., Kaminski, Naftali, Wenzel, Sally E.

“…) in 155 subjects with asthma and healthy control subjects from the Severe Asthma Research Program (SARP…”
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Clonal Architecture of Secondary Acute Myeloid Leukemia Autor Walter, Matthew J, Shen, Dong, Ding, Li, Shao, Jin, Koboldt, Daniel C, Chen, Ken, Larson, David E, McLellan, Michael D, Dooling, David, Abbott, Rachel, Fulton, Robert, Magrini, Vincent, Schmidt, Heather, Kalicki-Veizer, Joelle, O'Laughlin, Michelle, Fan, Xian, Grillot, Marcus, Witowski, Sarah, Heath, Sharon, Frater, John L, Eades, William, Tomasson, Michael, Westervelt, Peter, DiPersio, John F, Link, Daniel C, Mardis, Elaine R, Ley, Timothy J, Wilson, Richard K, Graubert, Timothy A

“…Whole-genome sequencing of samples from seven subjects with secondary acute myeloid leukemia identified somatic mutations…”
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Serum microRNAs as diagnostic markers of endometriosis: a comprehensive array-based analysis Autor Cosar, Emine, Mamillapalli, Ramanaiah, Ersoy, Gulcin Sahin, Cho, SihYun, Seifer, Benjamin, Taylor, Hugh S

“… Women with (n = 24) and without (n = 24) endometriosis. Serum samples were obtained from surgically diagnosed subjects…”
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On the utility of pooling biological samples in microarray experiments Autor Kendziorski, C, Irizarry, R A, Chen, K-S, Haag, J D, Gould, M N

“…Over 15% of the data sets catalogued in the Gene Expression Omnibus Database involve RNA samples that have been pooled before hybridization. Pooling affects…”
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Peripheral blood circular RNA hsa_circ_0124644 can be used as a diagnostic biomarker of coronary artery disease Autor Zhao, Zhenzhou, Li, Xuejie, Gao, Chuanyu, Jian, Dongdong, Hao, Peiyuan, Rao, Lixin, Li, Muwei

“… them in another group of subjects consisting of 30 control individuals and 30 CAD patients with different SYNTAX scores…”
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