Výsledky vyhledávání - "Non-Randomized Controlled Trials as Topic methods"
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Quasi-experimental study designs series—paper 7: assessing the assumptions
ISSN: 0895-4356, 1878-5921, 1878-5921Vydáno: United States Elsevier Inc 01.09.2017Vydáno v Journal of clinical epidemiology (01.09.2017)“…Quasi-experimental designs are gaining popularity in epidemiology and health systems research—in particular for the evaluation of health care practice,…”
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When Can Nonrandomized Studies Support Valid Inference Regarding Effectiveness or Safety of New Medical Treatments?
ISSN: 0009-9236, 1532-6535, 1532-6535Vydáno: United States 01.01.2022Vydáno v Clinical pharmacology and therapeutics (01.01.2022)“…The randomized controlled trial (RCT) is the gold standard for evaluating the causal effects of medications. Limitations of RCTs have led to increasing…”
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Critical appraisal of nonrandomized studies—A review of recommended and commonly used tools
ISSN: 1356-1294, 1365-2753, 1365-2753Vydáno: England Wiley Subscription Services, Inc 01.02.2019Vydáno v Journal of evaluation in clinical practice (01.02.2019)“…Rationale, aims, and objectives When randomized controlled trial data are limited or unavailable, or to supplement randomized controlled trial evidence, health…”
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Experimentation Without Randomised Controls
ISSN: 0305-182X, 1365-2842, 1365-2842Vydáno: England Wiley Subscription Services, Inc 01.08.2025Vydáno v Journal of oral rehabilitation (01.08.2025)“…ABSTRACT Background In an experimental study, researchers often have the ability to assign different treatments. This is often done with randomisation. There…”
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Incorporating non-randomized evidence in cochrane intervention reviews: a scoping review
ISSN: 0895-4356, 1878-5921, 1878-5921Vydáno: United States Elsevier Inc 01.07.2025Vydáno v Journal of clinical epidemiology (01.07.2025)“…“Non-randomized studies of interventions” (NRSI) can provide valuable insights into the real-world performance of interventions, especially when randomized…”
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Educational attainment and cardiovascular disease in the United States: A quasi-experimental instrumental variables analysis
ISSN: 1549-1676, 1549-1277, 1549-1676Vydáno: United States Public Library of Science 25.06.2019Vydáno v PLoS medicine (25.06.2019)“…There is ongoing debate about whether education or socioeconomic status (SES) should be inputs into cardiovascular disease (CVD) prediction algorithms and…”
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Including non-randomized studies of interventions in meta-analyses of randomized controlled trials changed the estimates in more than a third of the studies: evidence from an empirical analysis
ISSN: 0895-4356, 1878-5921, 1878-5921Vydáno: United States Elsevier Inc 01.07.2025Vydáno v Journal of clinical epidemiology (01.07.2025)“…There is a growing trend to include nonrandomized studies of interventions (NRSIs) in meta-analyses of randomized controlled trials (RCTs) for health…”
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Quasi-experimental study designs series—paper 1: introduction: two historical lineages
ISSN: 0895-4356, 1878-5921, 1878-5921Vydáno: United States Elsevier Inc 01.09.2017Vydáno v Journal of clinical epidemiology (01.09.2017)“…The objective of this study was to contrast the historical development of experiments and quasi-experiments and provide the motivation for a journal series on…”
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The Use of Quasi-experimental Designs for Vaccine Evaluation
ISSN: 1537-6591, 1537-6591Vydáno: United States 02.05.2019Vydáno v Clinical infectious diseases (02.05.2019)“…Randomized, controlled trials are not always possible to evaluate interventions targeting infectious disease. This is frequently the case when evaluating the…”
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Long-term Oncological Outcomes Following Anastomotic Leak in Rectal Cancer Surgery
ISSN: 1530-0358, 1530-0358Vydáno: United States 01.06.2020Vydáno v Diseases of the colon & rectum (01.06.2020)“…Anastomotic leak remains a critical complication after restorative rectal cancer surgery and is associated with significant morbidity and mortality rates,…”
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Integration of non-randomized studies with randomized controlled trials in meta-analyses of clinical studies: a meta-epidemiological study on effect estimation of interventions
ISSN: 1741-7015, 1741-7015Vydáno: London BioMed Central 02.12.2024Vydáno v BMC medicine (02.12.2024)“…Backgrounds Syntheses of non-randomized studies of interventions (NRSIs) and randomized controlled trials (RCTs) are increasingly used in decision-making. This…”
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Safety of Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Complex Perianal Fistulas Not Associated With Crohn's Disease: A Phase I Clinical Trial
ISSN: 1530-0358, 1530-0358Vydáno: United States 01.03.2021Vydáno v Diseases of the colon & rectum (01.03.2021)“…Anal fistula treatment aims to eradicate the fistula, preserve the sphincter, prevent recurrence, and allow an early return to daily activities for the…”
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The Revised WIC Food Package and Child Development: A Quasi-Experimental Study
ISSN: 1098-4275, 1098-4275Vydáno: United States 01.02.2021Vydáno v Pediatrics (Evanston) (01.02.2021)“…The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), one of the largest US safety net programs, was revised in 2009 to be more…”
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Quasi-experimental study designs series—paper 2: complementary approaches to advancing global health knowledge
ISSN: 0895-4356, 1878-5921, 1878-5921Vydáno: United States Elsevier Inc 01.09.2017Vydáno v Journal of clinical epidemiology (01.09.2017)“…Quasi-experiments have been infrequently used in the health sciences. Focusing on health systems implementation research, this article details key advantages…”
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Problematic meta-analyses: Bayesian and frequentist perspectives on combining randomized controlled trials and non-randomized studies
ISSN: 1471-2288, 1471-2288Vydáno: London BioMed Central 27.04.2024Vydáno v BMC medical research methodology (27.04.2024)“…Purpose In the literature, the propriety of the meta-analytic treatment-effect produced by combining randomized controlled trials (RCT) and non-randomized…”
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A systematic review showed more consideration is needed when conducting nonrandomized studies of interventions
ISSN: 0895-4356, 1878-5921, 1878-5921Vydáno: United States Elsevier Inc 01.01.2020Vydáno v Journal of clinical epidemiology (01.01.2020)“…The objective of this study was to evaluate the methodological conduct, reporting, and risk of bias of nonrandomized studies of interventions (NRSIs) funded by…”
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Prospective observational study to evaluate the use of musculoskeletal ultrasonography in rheumatoid arthritis management: the ECHO study
ISSN: 1462-0332, 1462-0332Vydáno: England 01.10.2020Vydáno v Rheumatology (Oxford, England) (01.10.2020)“…Since the creation of the Canadian Rheumatology Ultrasonography Society, an increasing number of rheumatologists has been trained in the use of musculoskeletal…”
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Advantages of multi-arm non-randomised sequentially allocated cohort designs for Phase II oncology trials
ISSN: 0007-0920, 1532-1827, 1532-1827Vydáno: England Nature Publishing Group 01.02.2022Vydáno v British journal of cancer (01.02.2022)“…Efficient trial designs are required to prioritise promising drugs within Phase II trials. Adaptive designs are examples of such designs, but their efficiency…”
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Magic Mirror, on the Wall-Which Is the Right Study Design of Them All?-Part I
ISSN: 1526-7598, 1526-7598Vydáno: United States 01.06.2017Vydáno v Anesthesia and analgesia (01.06.2017)“…The assessment of a new or existing treatment or intervention typically answers 1 of 3 research-related questions: (1) "Can it work?" (efficacy); (2) "Does it…”
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Improved Assessment of Chest pain Trial (IMPACT): assessing patients with possible acute coronary syndromes
ISSN: 0025-729X, 1326-5377, 1326-5377Vydáno: Australia 04.09.2017Vydáno v Medical journal of Australia (04.09.2017)“…Objective: To examine the safety and efficacy of the Improved Assessment of Chest pain Trial (IMPACT) protocol, a strategy for accelerated assessment of…”
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