Suchergebnisse - "Nolte, Ilja M"

Validity of (Ultra-)Short Recordings for Heart Rate Variability Measurements von Munoz, M. Loretto, van Roon, Arie, Riese, Harriëtte, Thio, Chris, Oostenbroek, Emma, Westrik, Iris, de Geus, Eco J. C., Gansevoort, Ron, Lefrandt, Joop, Nolte, Ilja M., Snieder, Harold

“… In order to investigate the applicability of routine 10s electrocardiogram (ECG) recordings for time-domain heart rate variability (HRV) calculation we …”
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Dominance genetic variation contributes little to the missing heritability for human complex traits von Zhu, Zhihong, Bakshi, Andrew, Vinkhuyzen, Anna A E, Hemani, Gibran, Lee, Sang Hong, Nolte, Ilja M, van Vliet-Ostaptchouk, Jana V, Snieder, Harold, Esko, Tonu, Milani, Lili, Mägi, Reedik, Metspalu, Andres, Hill, William G, Weir, Bruce S, Goddard, Michael E, Visscher, Peter M, Yang, Jian

“… For human complex traits, non-additive genetic variation has been invoked to explain "missing heritability," but its discovery is often neglected in …”
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DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring von Küpers, Leanne K, Xu, Xiaojing, Jankipersadsing, Soesma A, Vaez, Ahmad, la Bastide-van Gemert, Sacha, Scholtens, Salome, Nolte, Ilja M, Richmond, Rebecca C, Relton, Caroline L, Felix, Janine F, Duijts, Liesbeth, van Meurs, Joyce B, Tiemeier, Henning, Jaddoe, Vincent W, Wang, Xiaoling, Corpeleijn, Eva, Snieder, Harold

“… We examined whether the effect of maternal smoking during pregnancy on birthweight of the offspring was mediated by smoking-induced changes to DNA methylation …”
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A genome-wide association study of 24-hour urinary excretion of endocrine disrupting chemicals von Lu, Xueling, van der Meer, Thomas P., Kamali, Zoha, van Faassen, Martijn, Kema, Ido P., van Beek, André P., Xu, Xijin, Huo, Xia, Ani, Alireza, Nolte, Ilja M., Wolffenbuttel, Bruce H.R., van Vliet-Ostaptchouk, Jana V., Snieder, Harold

“… [Display omitted] •Unique genome-wide association study of multiple EDCs in 24-hour urine.•Four independent SNPs associated with EDCs through multi-trait GWAS …”
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Genotype–covariate interaction effects and the heritability of adult body mass index von Robinson, Matthew R, English, Geoffrey, Moser, Gerhard, Lloyd-Jones, Luke R, Triplett, Marcus A, Zhu, Zhihong, Nolte, Ilja M, van Vliet-Ostaptchouk, Jana V, Snieder, Harold, Esko, Tonu, Milani, Lili, Mägi, Reedik, Metspalu, Andres, Magnusson, Patrik K E, Pedersen, Nancy L, Ingelsson, Erik, Johannesson, Magnus, Yang, Jian, Cesarini, David, Visscher, Peter M

“… Matthew Robinson, Peter Visscher and colleagues use phenotypic data on 172,000 sibling pairs and phenotypic and SNP data on 150,832 unrelated individuals to …”
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Interleukin 6 and Development of Heart Failure With Preserved Ejection Fraction in the General Population von Chia, Yook Chin, Kieneker, Lyanne M., van Hassel, Gaston, Binnenmars, S. Heleen, Nolte, Ilja M., van Zanden, Jelmer J., van der Meer, Peter, Navis, Gerjan, Voors, Adriaan A., Bakker, Stephan J. L., De Borst, Martin H., Eisenga, Michele F.

“… Background The cause of heart failure with preserved ejection fraction (HFpEF) is poorly understood, and specific therapies are lacking. Previous studies …”
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Familial co-aggregation and shared genetics of cardiometabolic disorders and traits: data from the multi-generational Lifelines Cohort Study von Triatin, Rima D., Chen, Zekai, Ani, Alireza, Wang, Rujia, Hartman, Catharina A., Nolte, Ilja M., Thio, Chris H. L., Snieder, Harold

“… Background It is unclear to what extent genetics explain the familial clustering and the co-occurrence of distinct cardiometabolic disorders in the general …”
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C-Terminal Fibroblast Growth Factor 23, Iron Deficiency, and Mortality in Renal Transplant Recipients von Eisenga, Michele F, van Londen, Marco, Leaf, David E, Nolte, Ilja M, Navis, Gerjan, Bakker, Stephan J L, de Borst, Martin H, Gaillard, Carlo A J M

“… Iron deficiency (ID) is independently associated with an increased risk of death in renal transplant recipients (RTRs). ID promotes production and cleavage of …”
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A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren’s disease von Riesmeijer, Sophie A., Kamali, Zoha, Ng, Michael, Drichel, Dmitriy, Piersma, Bram, Becker, Kerstin, Layton, Thomas B., Nanchahal, Jagdeep, Nothnagel, Michael, Vaez, Ahmad, Hennies, Hans Christian, Werker, Paul M. N., Furniss, Dominic, Nolte, Ilja M.

“… Dupuytren’s disease (DD) is a highly heritable fibrotic disorder of the hand with incompletely understood etiology. A number of genetic loci, including Wnt …”
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Lipid and lipoprotein reference values from 133,450 Dutch Lifelines participants: Age- and gender-specific baseline lipid values and percentiles von Balder, Jan W., de Vries, Jeroen K., Nolte, Ilja M., Lansberg, Peter J., Kuivenhoven, Jan A., Kamphuisen, Pieter W.

“… Lipids and lipoproteins are recognized as the most important modifiable risk factors for cardiovascular disease. Although reference values for the major …”
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Iron Deficiency and Nephrotoxic Heavy Metals: A Dangerous Interplay? von Rawee, Pien, Kremer, Daan, Nolte, Ilja M., Leuvenink, Henri G. D., Touw, Daan J., De Borst, Martin H., Bakker, Stephan J. L., Hanudel, Mark R., Eisenga, Michele F.

“… Heavy metals are common in our environment, and all individuals are exposed to them to some extent. These toxic metals have several harmful effects on the …”
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Functional and internalizing disorders co-aggregate with cardiometabolic and immune-related diseases within families: a population-based cohort study von Steen, Olivier D., Bos, Martje, van Ockenburg, Sonja L., Zhou, Yiling, Nolte, Ilja M., Snieder, Harold, Kendler, Kenneth, Rosmalen, Judith G. M., van Loo, Hanna M.

“… Background Functional disorders share familial risk with internalizing disorders such as generalized anxiety disorder and depression, and are comorbid with …”
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Metasubtract: an R‐package to analytically produce leave‐one‐out meta‐analysis GWAS summary statistics von Nolte, Ilja M

“… Abstract Summary Summary statistics from a meta‐analysis of genome‐wide association studies (meta-GWAS) can be used for many follow-up analyses. One valuable …”
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Mitochondrial Genome Study Identifies Association Between Primary Open-Angle Glaucoma and Variants in MT-CYB, MT-ND4 Genes and Haplogroups von Lo Faro, Valeria, Nolte, Ilja M., Ten Brink, Jacoline B., Snieder, Harold, Jansonius, Nomdo M., Bergen, Arthur A., Lifelines Cohort Study

“… Background and purpose: Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by death of retinal ganglion cells and atrophy of the optic …”
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Corrigendum to “A genome-wide association study of 24-hour urinary excretion of endocrine disrupting chemicals” [Environ. Int., A Genome-Wide Association Study of 24-Hour Urinary Excretion of Endocrine Disrupting Chemicals 183 (2024) 108396] von Lu, Xueling, van der Meer, Thomas P., Kamali, Zoha, van Faassen, Martijn, Kema, Ido P., van Beek, André P., Xu, Xijin, Huo, Xia, Ani, Alireza, Nolte, Ilja M., Wolffenbuttel, Bruce H.R., van Vliet-Ostaptchouk, Jana V., Snieder, Harold

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Killer Cell Immunoglobulin-Like Receptor Haplotype B Modulates Susceptibility to EBV-Associated Classic Hodgkin Lymphoma von Jiang, Peijia, Nolte, Ilja M., Hepkema, Bouke G., Stulp, Marijke, van den Berg, Anke, Diepstra, Arjan

“… Tumor cells of classic Hodgkin lymphoma (cHL) are derived from antigen presenting B cells that are infected by Epstein Barr virus (EBV) in ~30% of patients …”
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Correction: Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study von Mac Giollabhui, Naoise, Slaney, Chloe, Hemani, Gibran, Foley, Éimear M., van der Most, Peter J., Nolte, Ilja M., Snieder, Harold, Davey Smith, George, Khandaker, Golam M., Hartman, Catharina A.

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Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study von Mac Giollabhui, Naoise, Slaney, Chloe, Hemani, Gibran, Foley, Éimear M., van der Most, Peter J., Nolte, Ilja M., Snieder, Harold, Davey Smith, George, Khandaker, Golam M., Hartman, Catharina A.

“… Inflammation is associated with a range of neuropsychiatric symptoms, but the issue of causality remains unclear. We used complementary non-genetic, genetic …”
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Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study von Nolte, Ilja M, van der Most, Peter J, Alizadeh, Behrooz Z, de Bakker, Paul IW, Boezen, H Marike, Bruinenberg, Marcel, Franke, Lude, van der Harst, Pim, Navis, Gerjan, Postma, Dirkje S, Rots, Marianne G, Stolk, Ronald P, Swertz, Morris A, Wolffenbuttel, Bruce HR, Wijmenga, Cisca, Snieder, Harold

“… Despite the recent explosive rise in number of genetic markers for complex disease traits identified in genome-wide association studies, there is still a large …”
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MicroRNA High Throughput Loss-of-Function Screening Reveals an Oncogenic Role for miR-21-5p in Hodgkin Lymphoma von Yuan, Ye, Niu, Fubiao, Nolte, Ilja M., Koerts, Jasper, de Jong, Debora, Rutgers, Bea, Osinga, Jan, Azkanaz, Maria, Terpstra, Martijn, Bystrykh, Leonid, Diepstra, Arjan, Visser, Lydia, Dzikiewicz-Krawczyk, Agnieszka, Kok, Klaas, Kluiver, Joost , van den Berg, Anke

“… Background/Aims: Classical Hodgkin lymphoma (cHL) is among the most frequent lymphoma subtypes. The tumor cells originate from crippled germinal center (GC)-B …”
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