Výsledky vyhľadávania - "Nicholson, Robert"

Protein kinase CK2 triggers cytosolic zinc signaling pathways by phosphorylation of zinc channel ZIP7 Autor Taylor, Kathryn M, Hiscox, Stephen, Nicholson, Robert I, Hogstrand, Christer, Kille, Peter

“…The transition element zinc, which has recently been identified as an intracellular second messenger, has been implicated in various signaling pathways,…”
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Migraine-Related Stigma and Its Relationship to Disability, Interictal Burden, and Quality of Life: Results of the OVERCOME (US) Study Autor Shapiro, Robert E, Nicholson, Robert A, Seng, Elizabeth K, Buse, Dawn C, Reed, Michael L, Zagar, Anthony J, Ashina, Sait, Muenzel, E Jolanda, Hutchinson, Susan, Pearlman, Eric M, Lipton, Richard B

“…This population-based analysis characterizes the relative frequency of migraine-related stigma and its cross-sectional relationship to migraine outcomes. We…”
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Migraine-Related Stigma and Its Relationship to Disability, Interictal Burden, and Quality of Life Autor Shapiro, Robert E, Nicholson, Robert A, Seng, Elizabeth K, Buse, Dawn C, Reed, Michael L, Zagar, Anthony J, Ashina, Sait, Muenzel, E Jolanda, Hutchinson, Susan, Pearlman, Eric M, Lipton, Richard B

“…This population-based analysis characterizes the relative frequency of migraine-related stigma and its cross-sectional relationship to migraine outcomes. We…”
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The not so hidden impact of interictal burden in migraine: A narrative review Autor Vincent, Maurice, Viktrup, Lars, Nicholson, Robert A., Ossipov, Michael H., Vargas, Bert B.

“…Migraine is a highly prevalent neurological disease of varying attack frequency. Headache attacks that are accompanied by a combination of impact on daily…”
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Applications of Electrical Load Modelling in Digital Twins of Power Systems Autor Jayasinghe, Hasith, Gunawardane, Kosala, Nicholson, Robert

“…Accurate electrical load modeling is crucial for both transient and steady-state power system studies. Although various load modeling techniques are documented…”
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Diagnosis, consultation, treatment, and impact of migraine in the US: Results of the OVERCOME (US) study Autor Lipton, Richard B., Nicholson, Robert A., Reed, Michael L., Araujo, Andre B., Jaffe, Dena H., Faries, Douglas E., Buse, Dawn C., Shapiro, Robert E., Ashina, Sait, Cambron‐Mellott, M. Janelle, Rowland, John C., Pearlman, Eric M.

“…Objective The ObserVational survey of the Epidemiology, tReatment and Care of MigrainE (OVERCOME; United States) study is a multicohort, longitudinal web…”
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ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer Cells Autor Taylor, Kathryn M, Vichova, Petra, Jordan, Nicola, Hiscox, Stephen, Hendley, Rhiannon, Nicholson, Robert I

“…Antiestrogens such as tamoxifen are the mainstay of treatment for estrogen receptor-positive breast cancer. However, their effectiveness is limited by the…”
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DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer Autor Stone, Andrew, Zotenko, Elena, Locke, Warwick J., Korbie, Darren, Millar, Ewan K. A., Pidsley, Ruth, Stirzaker, Clare, Graham, Peter, Trau, Matt, Musgrove, Elizabeth A., Nicholson, Robert I., Gee, Julia M. W., Clark, Susan J.

“…Expression of oestrogen receptor (ESR1) determines whether a breast cancer patient receives endocrine therapy, but does not guarantee patient response. The…”
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Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival Autor Law, Jennifer H, Habibi, Golareh, Hu, Kaiji, Masoudi, Hamid, Wang, Michelle Y C, Stratford, Anna L, Park, Eugene, Gee, Julia M W, Finlay, Pauline, Jones, Helen E, Nicholson, Robert I, Carboni, Joan, Gottardis, Marco, Pollak, Michael, Dunn, Sandra E

“…Drugs that target the insulin-like growth factor-I receptor (IGF-IR) and/or insulin receptor (IR) are currently under investigation for a variety of…”
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Impact of galcanezumab on total pain burden: findings from phase 3 randomized, double-blind, placebo-controlled studies in patients with episodic or chronic migraine (EVOLVE-1, EVOLVE-2, and REGAIN trials) Autor Ailani, Jessica, Andrews, J. Scott, Rettiganti, Mallikarjuna, Nicholson, Robert A.

“…Background Focus on the frequency of migraine pain may undervalue the total burden of migraine as pain duration and severity may present unique, additive…”
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Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer Autor Yang, Jun, AlTahan, Alaa, Jones, Dylan T, Buffa, Francesca M, Bridges, Esther, Interiano, Rodrigo B, Qu, Chunxu, Vogt, Nathan, Li, Ji-Liang, Baban, Dilair, Ragoussis, Jiannis, Nicholson, Robert, Davidoff, Andrew M, Harris, Adrian L

“…A majority of breast cancers are driven by estrogen via estrogen receptor-α (ERα). Our previous studies indicate that hypoxia-inducible factor 1α (HIF-1α)…”
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Stigmatizing attitudes toward people with migraine by people without active migraine: results of the OVERCOME (US) study Autor Shapiro, Robert E., Viktrup, Lars, Muenzel, Eva Jolanda, Buse, Dawn C., Zagar, Anthony J., Ashina, Sait, Hutchinson, Susan, Nicholson, Robert A., Lipton, Richard B.

“…Background Migraine is associated with various types of stigma. This study aims to evaluate stigmatizing attitudes towards people with migraine by people…”
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Rates and risk factors for migraine progression using multiple definitions of progression: Results of the longitudinal OVERCOME (US) study Autor Buse, Dawn C., Muenzel, E. Jolanda, Zagar, Anthony J., Mehrabadi, Ali Sheikhi, Shapiro, Robert E., Kim, Gilwan, Ashina, Sait, Nicholson, Robert A., Lipton, Richard B.

“…Objective To estimate rates of migraine progression and assess predictors of progression in a large, longitudinal cohort study using the traditional definition…”
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Acute migraine medication adherence, migraine disability and patient satisfaction: A naturalistic daily diary study Autor Seng, Elizabeth K, Robbins, Matthew S, Nicholson, Robert A

“…Objective To examine the influence of acute migraine medication adherence on migraine disability and acute medication satisfaction. Methods Adults with…”
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Machine learning identifies factors most associated with seeking medical care for migraine: Results of the OVERCOME (US) study Autor Ashina, Sait, Muenzel, E. Jolanda, Nicholson, Robert A., Zagar, Anthony J., Buse, Dawn C., Reed, Michael L., Shapiro, Robert E., Hutchinson, Susan, Pearlman, Eric M., Lipton, Richard B.

“…Objective Utilize machine learning models to identify factors associated with seeking medical care for migraine. Background Migraine is a leading cause of…”
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Patterns of calcitonin gene-related peptide monoclonal antibody use in people with migraine: Results of the OVERCOME (US) study Autor Ashina, Sait, Kim, Gilwan, Muenzel, E Jolanda, Buse, Dawn C, Zagar, Anthony J, Zakharyan, Armen, Shapiro, Robert E, Nicholson, Robert A, Pearlman, Eric M, Lipton, Richard B

“…BackgroundUnderstanding characteristics and reasons associated with using calcitonin gene-related peptide monoclonal antibodies (CGRP mAb) for migraine…”
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Assessing evidence-based medicine and opioid/barbiturate as first-line acute treatment of pediatric migraine and primary headache: A retrospective observational study of health systems data Autor Seng, Elizabeth K, Gelfand, Amy A, Nicholson, Robert A

“…To evaluate providers' use and predictors of evidence-based medicine or opioid/barbiturate as first-line acute treatment for children's initial presentation of…”
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Development of the Migraine‐Related Stigma (MiRS) Questionnaire: Results of the OVERCOME (US) Study Autor Seng, Elizabeth K., Muenzel, E. Jolanda, Shapiro, Robert E., Buse, Dawn C., Reed, Michael L., Zagar, Anthony J., Ashina, Sait, Hutchinson, Susan, Nicholson, Robert A., Lipton, Richard B.

“…Background Stigma is emerging as an important social contributor to migraine‐related disability and other outcomes. Currently, there are no published validated…”
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Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen Autor Hurtado, Antoni, Holmes, Kelly A., Geistlinger, Timothy R., Hutcheson, Iain R., Nicholson, Robert I., Brown, Myles, Jiang, Jie, Howat, William J., Ali, Simak, Carroll, Jason S.

“…Tamoxifen resistance mechanism Tamoxifen is commonly used for breast cancer therapy, but a proportion of patients become resistant to the treatment, and their…”
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Lifetime history of an anxiety or depression disorder and adherence to medications used for the acute treatment of migraine Autor Butler, Nicole, Snyder, Ivy C., Korn, Talia G., Nicholson, Robert A., Robbins, Matthew S., Seng, Elizabeth K.

“…Objective In this secondary analysis of mobile health headache diary data, we evaluated the relationship between adherence to medication used for the acute…”
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