Výsledky vyhľadávania - "Niccolai, Rachele"

Cholesterol biosynthesis as a drug-induced vulnerability in diffuse large B cell lymphoma insensitive to EZH2 inhibition Autor Niccolai, Rachele, Göbel, Camiel, Ndoj, Klevis, Kreft, Maaike, Kuiken, Hendrik J., Lieftink, Cor, Morris, Ben, Yska, Sietse D., Hendrix, Sebastian, van den Broek, Bram, Pappalardo, Vincent, Kersten, Marie José, Beijersbergen, Roderick L., Zelcer, Noam, van Leeuwen, Fred, Jacobs, Heinz

“…•GCB-DLBCL insensitive to EZH2 inhibition become dependent on cholesterol synthesis.•This dependency relates to altered LDLR subcellular localization and LDL…”
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Thrombotic Events in MIS-C Patients: A Single Case Report and Literature Review Autor Maniscalco, Valerio, Niccolai, Rachele, Marrani, Edoardo, Maccora, Ilaria, Bertini, Federico, Pagnini, Ilaria, Simonini, Gabriele, Lasagni, Donatella, Trapani, Sandra, Mastrolia, Maria Vincenza

“…Multisystem Inflammatory Syndrome in Children (MIS-C) is a systemic hyperinflammatory disorder that is associated with a hypercoagulable state and a higher…”
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Epigenetically programmed identity crisis to combat diffuse large B cell lymphoma Autor Niccolai, Rachele, Göbel, Camiel, Jacobs, Heinz

“…A substantial fraction of patients with diffuse large B cell lymphoma (DLBCL) does not respond to standard-of-care immunochemotherapy.B cell differentiation is…”
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Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of diffuse large B-cell lymphoma Autor Göbel, Camiel, Niccolai, Rachele, de Groot, Marnix H P, Jayachandran, Jayashree, Traets, Joleen, Kloosterman, Daan J, Gregoricchio, Sebastian, Morris, Ben, Kreft, Maaike, Song, Ji-Ying, Azarang, Leyla, Kasa, Eirini, Oskam, Nienke, de Groot, Daniel, Hoekman, Liesbeth, Bleijerveld, Onno B, Kersten, Marie José, Aslam, Muhammad A, van Leeuwen, Fred, Jacobs, Heinz

“…Differentiation of antigen-activated B cells into proproliferative germinal center (GC) B cells depends on the activity of the transcription factors…”
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Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of Diffuse Large B Cell Lymphoma Autor Göbel, Camiel, Niccolai, Rachele, de Groot, Marnix H.P., Jayachandran, Jayashree, Traets, Joleen, Morris, Ben, Song, Ji-Ying, Azarang, Leyla, Kasa, Eirini, de Groot, Daniel, Kreft, Maaike, Kersten, Marie José, Aslam, Muhammad A., van Leeuwen, Fred, Jacobs, Heinz

“…Differentiation of antigen-activated B cells into pro-proliferative germinal center (GC) B cells depends on the activity of the transcription factor MYC and…”
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