Suchergebnisse - "Neurotoxicity Syndromes - pathology"

Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits von Wu, Jing, Yang, Jian-Jun, Cao, Yan, Li, Huihui, Zhao, Hongting, Yang, Shuofei, Li, Kuanyu

“… ) could be detrimental to cognitive development in young subjects and might also contribute to accelerated neurodegeneration in the elderly …”
Volltext

Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder von Meier, Timothy B., Drevets, Wayne C., Wurfel, Brent E., Ford, Bart N., Morris, Harvey M., Victor, Teresa A., Bodurka, Jerzy, Teague, T. Kent, Dantzer, Robert, Savitz, Jonathan

“… •Thickness of right BA24 and right BA32 was reduced in major depressive disorder.•Serum KynA/3HK and KynA/QA was reduced in MDD.•CRP was inversely associated …”
Volltext

Revisiting Astrocytic Roles in Methylmercury Intoxication von Arrifano, Gabriela de Paula, Augusto-Oliveira, Marcus, Souza-Monteiro, José Rogério, Macchi, Barbarella de Matos, Lima, Rafael Rodrigues, Suñol, Cristina, do Nascimento, José Luis Martins, Crespo-Lopez, Maria Elena

“… ’ strategic functions in brain homeostasis, these cells became the subject of several studies on MeHg intoxication …”
Volltext

Liposome‐Encapsulated Melatonin Mitigates Amoxicillin‐Induced Neurotoxicity in a Zebrafish von Balakrishnan, Ranjith, Subbarayan, Rajasekaran, Shrestha, Rupendra, Srinivasan, Dhasarathdev, Shrestha, Reena, Chauhan, Ankush, Murugan Girija, Dinesh

“… ABSTRACT Amoxicillin (Amx), a β‐Lactam antibiotic frequently used to treat bacterial infections, has been linked to neurological effects, including anxiety, …”
Volltext

Human-induced pluripotent stems cells as a model to dissect the selective neurotoxicity of methylmercury von Prince, Lisa M., Aschner, Michael, Bowman, Aaron B.

“… Methylmercury (MeHg) is a potent neurotoxicant affecting both the developing and mature central nervous system (CNS) with apparent indiscriminate disruption of …”
Volltext

Plant components can reduce methylmercury toxication: A mini-review von Chang, Jie, Zhou, Yun, Wang, Qiang, Aschner, Michael, Lu, Rongzhu

“… Methylmercury (MeHg) is a ubiquitous environmental pollutant, with the nervous system as its main target; however, the neurotoxic mechanisms of MeHg have not …”
Volltext

Persistent chemoneuropathy in patients receiving the plant alkaloids paclitaxel and vincristine von Boyette-Davis, Jessica A., Cata, Juan P., Driver, Larry C., Novy, Diane M., Bruel, Brian M., Mooring, Deidre L., Wendelschafer-Crabb, Gwen, Kennedy, William R., Dougherty, Patrick M.

“… from 18 healthy control subjects. In addition, skin biopsies were obtained to investigate changes in the density …”
Volltext

The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons von Avdoshina, Valeria, Fields, Jerel Adam, Castellano, Paul, Dedoni, Simona, Palchik, Guillermo, Trejo, Margarita, Adame, Anthony, Rockenstein, Edward, Eugenin, Eliseo, Masliah, Eliezer, Mocchetti, Italo

“… The present study was undertaken to characterize novel mechanisms of HIV neurotoxicity that may explain how HIV subjects develop neuronal degeneration …”
Volltext

Plasma Homocysteine Concentration is Associated with the Expression Level of Folate Receptor 3 von Yoshitomi, Ren, Nakayama, Kai, Yamashita, Shuya, Kumazoe, Motofumi, Lin, Ting-An, Mei, Chen-Yi, Marugame, Yuki, Fujimura, Yoshinori, Maeda-Yamamoto, Mari, Kuriyama, Shinichi, Tachibana, Hirofumi

“… Subjects with a high expression of FOLR3 exhibited low levels of plasma homocysteine. The ectopic expression of FOLR3 enhanced cell growth, and the enhanced effect was neutralised …”
Volltext

Is cannabis neurotoxic for the healthy brain? A meta‐analytical review of structural brain alterations in non‐psychotic users von Rocchetti, Matteo, Crescini, Alessandra, Borgwardt, Stefan, Caverzasi, Edgardo, Politi, Pierluigi, Atakan, Zerrin, Fusar‐Poli, Paolo

“… ‐psychotic subjects who were using or not using cannabis. We specifically tested the hypothesis that cannabis use can alter grey and white matter in non‐psychotic subjects …”
Volltext

Biochemical and toxicological evidence of neurological effects of pesticides: The example of Parkinson's disease von Moretto, A., Colosio, C.

“… Parkinson's disease (PD) is frequently reported to be associated with pesticide exposure but the issue has not yet been solved because the data are …”
Volltext

Monocrotophos induced oxidative damage associates with severe acetylcholinesterase inhibition in rat brain von Kazi, Amajad Iqbal, Oommen, Anna

“… ► Acute monocrotophos poisoning resulted in differential acetylcholinesterase inhibition in different rat brain regions. ► Neurotoxicity of monocrotophos …”
Volltext

The potential of induced pluripotent stem cells as a translational model for neurotoxicological risk von Kumar, Kevin K., Aboud, Asad A., Bowman, Aaron B.

“… Owing to the challenges of human subject research and the real possibility of species specific toxicological responses, neuronal lineages derived from human embryonic stem cells (hESCs …”
Volltext

General anesthetics and cytotoxicity: possible implications for brain health von Armstrong, Ryden, Xu, Fenglian, Arora, Anish, Rasic, Nivez, Syed, Naweed I.

“… unknown, especially in the young and aging brain. Objective: Taking advantage of our clinical and basic science expertise, here we subject the reader to an interesting perspective vis-à …”
Volltext

Functional MRI approach to developmental methylmercury and polychlorinated biphenyl neurotoxicity von White, Roberta F., Palumbo, Carole L., Yurgelun-Todd, Deborah A., Heaton, Kristin J., Weihe, Pal, Debes, Frodi, Grandjean, Philippe

“… ► fMRI shows promise as a tool for detecting functional brain alterations in subjects with prenatal neurotoxicant exposures …”
Volltext

Alterations of white matter tracts following neurotoxic hippocampal lesions in macaque monkeys: A diffusion tensor imaging study von Shamy, J.L., Carpenter, D.M., Fong, S.G., Murray, E.A., Tang, C.Y., Hof, P.R., Rapp, P.R.

“… Two years postlesion, structural MRI, and DTI sequences were acquired for each subject …”
Volltext

ER chaperone–metal interactions: Links to protein folding disorders von Tiffany-Castiglioni, Evelyn, Qian, Yongchang

“… ” chaperone GRP78 in the endoplasmic reticulum is a compelling subject for investigation in this context because it is …”
Volltext

[18F]FDG-PET as an imaging biomarker to NMDA receptor antagonist-induced neurotoxicity von Shirakawa, Takafumi, Mitsuoka, Keisuke, Kuroda, Kanae, Miyoshi, Sosuke, Shiraki, Katsuhisa, Naraoka, Hitoshi, Noda, Akihiro, Fujikawa, Akihiko, Fujiwara, Michio

“… Positron emission tomography (PET) is an effective tool for noninvasive examination of the body and provides a range of functional information. PET imaging …”
Weitere Angaben

Histopathological observations in the brains of children exposed to inhalational anesthetic agents: a retrospective autopsy-based study von Green, M S, Aman, M M, Stevens, L, Voralu, K, Saththasivam, P, Mychaskiw, G, Katsetos, C D

“… The relevance of data derived from controlled experimental studies to human neuropathology is a subject of debate …”
Weitere Angaben

Increased white matter hyperintensities in male methamphetamine abusers von Bae, Soojeong C., Lyoo, In Kyoon, Sung, Young Hoon, Yoo, Jaeun, Chung, Ain, Yoon, Su-Jung, Kim, Dai-Jin, Hwang, Jaeuk, Kim, Seog Ju, Renshaw, Perry F.

“… ) on brain magnetic resonance (MR) imaging in methamphetamine (MA) abusers. Thirty-three MA abusers and 32 age- and gender-matched healthy comparison subjects were studied …”
Volltext