Výsledky vyhľadávania - "Neoplasia (New York, N.Y.)"

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses Autor Chandrashekar, Darshan S., Bashel, Bhuwan, Balasubramanya, Sai Akshaya Hodigere, Creighton, Chad J., Ponce-Rodriguez, Israel, Chakravarthi, Balabhadrapatruni V.S.K., Varambally, Sooryanarayana

“…Genomics data from The Cancer Genome Atlas (TCGA) project has led to the comprehensive molecular characterization of multiple cancer types. The large sample…”
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Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients Autor Frankel, Arthur E., Coughlin, Laura A., Kim, Jiwoong, Froehlich, Thomas W., Xie, Yang, Frenkel, Eugene P., Koh, Andrew Y.

“…This is the first prospective study of the effects of human gut microbiota and metabolites on immune checkpoint inhibitor (ICT) response in metastatic melanoma…”
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UALCAN: An update to the integrated cancer data analysis platform Autor Chandrashekar, Darshan Shimoga, Karthikeyan, Santhosh Kumar, Korla, Praveen Kumar, Patel, Henalben, Shovon, Ahmedur Rahman, Athar, Mohammad, Netto, George J., Qin, Zhaohui S., Kumar, Sidharth, Manne, Upender, Creighton, Chad J., Varambally, Sooryanarayana

“…Cancer genomic, transcriptomic, and proteomic profiling has generated extensive data that necessitate the development of tools for its analysis and…”
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Spherical Cancer Models in Tumor Biology Autor Weiswald, Louis-Bastien, Bellet, Dominique, Dangles-Marie, Virginie

“…Three-dimensional (3D) in vitro models have been used in cancer research as an intermediate model between in vitro cancer cell line cultures and in vivo tumor…”
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ONC201 and imipridones: Anti-cancer compounds with clinical efficacy Autor Prabhu, Varun Vijay, Morrow, Sara, Rahman Kawakibi, Abed, Zhou, Lanlan, Ralff, Marie, Ray, Jocelyn, Jhaveri, Aakash, Ferrarini, Isacco, Lee, Young, Parker, Cassandra, Zhang, Yiqun, Borsuk, Robyn, Chang, Wen-I, Honeyman, Joshua N., Tavora, Fabio, Carneiro, Benedito, Raufi, Alexander, Huntington, Kelsey, Carlsen, Lindsey, Louie, Anna, Safran, Howard, Seyhan, Attila A., Tarapore, Rohinton S., Schalop, Lee, Stogniew, Martin, Allen, Joshua E., Oster, Wolfgang, El-Deiry, Wafik S.

“…ONC201 was originally discovered as TNF-Related Apoptosis Inducing Ligand (TRAIL)-inducing compound TIC10. ONC201 appears to act as a selective antagonist of…”
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Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells Autor Hao, Shihui, Yu, Jiang, He, Wanming, Huang, Qiong, Zhao, Yang, Liang, Bishan, Zhang, Shuyi, Wen, Zhaowei, Dong, Shumin, Rao, Jinjun, Liao, Wangjun, Shi, Min

“…BACKGROUND: Ferroptosis is a recently discovered form of iron-dependent nonapoptotic cell death. It is characterized by loss of the activity of the lipid…”
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Immune Signature-Based Subtypes of Cervical Squamous Cell Carcinoma Tightly Associated with Human Papillomavirus Type 16 Expression, Molecular Features, and Clinical Outcome Autor Lu, Xiaofan, Jiang, Liyun, Zhang, Liya, Zhu, Yue, Hu, Wenjun, Wang, Jiashuo, Ruan, Xinjia, Xu, Zhengbao, Meng, Xiaowei, Gao, Jun, Su, Xiaoping, Yan, Fangrong

“…Substantial heterogeneity exists within cervical cancer that is generally infected by human papillomavirus (HPV). However, the most common histological subtype…”
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STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications Autor Tošić, Isidora, Frank, David A.

“…The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is activated constitutively in a wide array of human cancers. It…”
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Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment Autor Kregel, Steven, Wang, Chao, Han, Xin, Xiao, Lanbo, Fernandez-Salas, Ester, Bawa, Pushpinder, McCollum, Brooke L., Wilder-Romans, Kari, Apel, Ingrid J., Cao, Xuhong, Speers, Corey, Wang, Shaomeng, Chinnaiyan, Arul M.

“…Androgen receptor (AR) antagonists, such as enzalutamide, have had a major impact on the treatment of metastatic castration-resistant prostate cancer (CRPC)…”
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Development and prevalence of castration-resistant prostate cancer subtypes Autor Vellky, Jordan E., Ricke, William A.

“…Castration-resistant prostate cancer (CRPC) occurs when prostate cancer (CaP) progresses under therapy-induced castrate conditions. Several mechanisms have…”
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The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science Autor Lilly, Jena V., Rokita, Jo Lynne, Mason, Jennifer L., Patton, Tatiana, Stefankiewiz, Stephanie, Higgins, David, Trooskin, Gerri, Larouci, Carina A., Arya, Kamnaa, Appert, Elizabeth, Heath, Allison P., Zhu, Yuankun, Brown, Miguel A., Zhang, Bo, Farrow, Bailey K., Robins, Shannon, Morgan, Allison M., Nguyen, Thinh Q., Frenkel, Elizabeth, Lehmann, Kaitlin, Drake, Emily, Sullivan, Catherine, Plisiewicz, Alexa, Coleman, Noel, Patterson, Luke, Koptyra, Mateusz, Helili, Zeinab, Van Kuren, Nicholas, Young, Nathan, Kim, Meen Chul, Friedman, Christopher, Lubneuski, Alex, Blackden, Christopher, Williams, Marti, Baubet, Valerie, Tauhid, Lamiya, Galanaugh, Jamie, Boucher, Katie, Ijaz, Heba, Cole, Kristina A., Choudhari, Namrata, Santi, Mariarita, Moulder, Robert W., Waller, Jonathan, Rife, Whitney, Diskin, Sharon J., Mateos, Marion, Parsons, Donald W., Pollack, Ian F., Goldman, Stewart, Leary, Sarah, Caporalini, Chiara, Buccoliero, Anna Maria, Scagnet, Mirko, Haussler, David, Hanson, Derek, Firestein, Ron, Cain, Jason, Phillips, Joanna J., Gupta, Nalin, Mueller, Sabine, Grant, Gerald, Monje-Deisseroth, Michelle, Partap, Sonia, Greenfield, Jeffrey P., Hashizume, Rintaro, Smith, Amy, Zhu, Shida, Johnston, James M., Fangusaro, Jason R., Miller, Matthew, Wood, Matthew D., Gardner, Sharon, Carter, Claire L., Prolo, Laura M., Pisapia, Jared, Pehlivan, Katherine, Franson, Andrea, Niazi, Toba, Rubin, Josh, Abdelbaki, Mohamed, Ziegler, David S., Lindsay, Holly B., Stucklin, Ana Guerreiro, Gerber, Nicolas, Vaske, Olena M., Quinsey, Carolyn, Rood, Brian R., Nazarian, Javad, Raabe, Eric, Jackson, Eric M., Stapleton, Stacie, Lober, Robert M., Kram, David E., Koschmann, Carl, Storm, Phillip B., Lulla, Rishi R., Prados, Michael, Resnick, Adam C., Waanders, Angela J.

“…Pediatric brain tumors are the leading cause of cancer-related death in children in the United States and contribute a disproportionate number of potential…”
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Snail-overexpressing Cancer Cells Promote M2-Like Polarization of Tumor-Associated Macrophages by Delivering MiR-21-Abundant Exosomes Autor Hsieh, Chia-Hsin, Tai, Shyh-Kuan, Yang, Muh-Hwa

“…Epithelial-mesenchymal transition (EMT) is a major event during cancer progression and metastasis; however, the definitive role of EMT in remodeling tumor…”
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What's New in SCLC? A Review Autor Oronsky, Bryan, Reid, Tony R., Oronsky, Arnold, Carter, Corey A.

“…A few years ago the answer to the question in the title of this review would have been, “unfortunately not much” or even “nothing”, likely eliciting knowing…”
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Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas Autor Oronsky, Bryan, Ma, Patrick C., Morgensztern, Daniel, Carter, Corey A.

“…This review covers the diverse topic of neuroendocrine neoplasms (NENs), a relatively rare and heterogeneous tumor type, comprising ~2% of all malignancies,…”
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Gut microbiota-derived short-chain fatty acids promote prostate cancer progression via inducing cancer cell autophagy and M2 macrophage polarization Autor Liu, Yufei, Zhou, Quan, Ye, Fangdie, Yang, Chen, Jiang, Haowen

“…•CRPC patients have abundant SCFAs-producing gut microbiotas.•CRPC fecal microbiota transplantation or SCFAs gavage to mice promote PCa progression.•SCFAs can…”
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Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era Autor Manoharan, Neevika, Liu, Kevin X., Mueller, Sabine, Haas-Kogan, Daphne A., Bandopadhayay, Pratiti

“…•Pediatric low-grade glioma (pLGG) is a MAPK pathway-altered disease with novel therapeutic options.•Clinical trials are vital in translation of targeted…”
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Advancing glioblastoma treatment by targeting metabolism Autor Zhao, Jinyi, Ma, Xuemei, Gao, Peixian, Han, Xueqi, Zhao, Pengxiang, Xie, Fei, Liu, Mengyu

“…Alterations in cellular metabolism are important hallmarks of glioblastoma(GBM). Metabolic reprogramming is a critical feature as it meets the higher…”
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Pamiparib is a potent and selective PARP inhibitor with unique potential for the treatment of brain tumor Autor Xiong, Yao, Guo, Yin, Liu, Ye, Wang, Hexiang, Gong, Wenfeng, Liu, Yong, Wang, Xing, Gao, Yajuan, Yu, Fenglong, Su, Dan, Wang, Fan, Zhu, Yutong, Zhao, Yuan, Wu, Yiyuan, Qin, Zhen, Sun, Xuebing, Ren, Bo, Jiang, Bin, Jin, Wei, Shen, Zhirong, Tang, Zhiyu, Song, Xiaomin, Wang, Lai, Liu, Xuesong, Zhou, Changyou, Jiang, Beibei

“…Pamiparib, an investigational Poly (ADP-ribose) polymerase (PARP) inhibitor in clinical development, demonstrates excellent selectivity for both PARP1 and…”
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CXCL1-Mediated Interaction of Cancer Cells with Tumor-Associated Macrophages and Cancer-Associated Fibroblasts Promotes Tumor Progression in Human Bladder Cancer Autor Miyake, Makito, Hori, Shunta, Morizawa, Yosuke, Tatsumi, Yoshihiro, Nakai, Yasushi, Anai, Satoshi, Torimoto, Kazumasa, Aoki, Katsuya, Tanaka, Nobumichi, Shimada, Keiji, Konishi, Noboru, Toritsuka, Michihiro, Kishimoto, Toshifumi, Rosser, Charles J., Fujimoto, Kiyohide

“…Tumor-associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs) are reported to be associated with poor prognosis, depending on their pro-tumoral…”
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Rosmarinic acid represses colitis-associated colon cancer: A pivotal involvement of the TLR4-mediated NF-κB-STAT3 axis Autor Jin, Bo-Ram, Chung, Kyung-Sook, Hwang, Soonjae, Hwang, Sam Noh, Rhee, Ki-Jong, Lee, Minho, An, Hyo-Jin

“…Previously, we found that rosmarinic acid (RA) exerted anti-inflammatory activities in a dextran sulfate sodium (DSS)-induced colitis model. Here, we…”
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