Výsledky vyhľadávania - "Nefedova, Yulia"

Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway Autor Alicea-Torres, Kevin, Sanseviero, Emilio, Gui, Jun, Chen, Jinyun, Veglia, Filippo, Yu, Qiujin, Donthireddy, Laxminarasimha, Kossenkov, Andrew, Lin, Cindy, Fu, Shuyu, Mulligan, Charles, Nam, Brian, Masters, Gregory, Denstman, Fred, Bennett, Joseph, Hockstein, Neil, Rynda-Apple, Agnieszka, Nefedova, Yulia, Fuchs, Serge Y., Gabrilovich, Dmitry I.

“…Myeloid-derived suppressor cells (MDSC) are pathologically activated neutrophils and monocytes with potent immune suppressive activity. These cells play an…”
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Fatty acid transport protein 2 reprograms neutrophils in cancer Autor Veglia, Filippo, Tyurin, Vladimir A., Blasi, Maria, De Leo, Alessandra, Kossenkov, Andrew V., Donthireddy, Laxminarasimha, To, Tsun Ki Jerrick, Schug, Zach, Basu, Subhasree, Wang, Fang, Ricciotti, Emanuela, DiRusso, Concetta, Murphy, Maureen E., Vonderheide, Robert H., Lieberman, Paul M., Mulligan, Charles, Nam, Brian, Hockstein, Neil, Masters, Gregory, Guarino, Michael, Lin, Cindy, Nefedova, Yulia, Black, Paul, Kagan, Valerian E., Gabrilovich, Dmitry I.

“…Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) are pathologically activated neutrophils that are crucial for the regulation of immune responses…”
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Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells Autor Tang, Chih-Hang Anthony, Zundell, Joseph A, Ranatunga, Sujeewa, Lin, Cindy, Nefedova, Yulia, Del Valle, Juan R, Hu, Chih-Chi Andrew

“…Endoplasmic reticulum (ER) stress responses through the IRE-1/XBP-1 pathway are required for the function of STING (TMEM173), an ER-resident transmembrane…”
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Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils Autor Perego, Michela, Tyurin, Vladimir A, Tyurina, Yulia Y, Yellets, Jonathan, Nacarelli, Timothy, Lin, Cindy, Nefedova, Yulia, Kossenkov, Andrew, Liu, Qin, Sreedhar, Sreesha, Pass, Harvey, Roth, Johannes, Vogl, Thomas, Feldser, David, Zhang, Rugang, Kagan, Valerian E, Gabrilovich, Dmitry I

“…Tumor recurrence years after seemingly successful treatment of primary tumors is one of the major causes of mortality in patients with cancer. Reactivation of…”
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Transitory presence of myeloid-derived suppressor cells in neonates is critical for control of inflammation Autor He, Yu-Mei, Li, Xing, Perego, Michela, Nefedova, Yulia, Kossenkov, Andrew V, Jensen, Erik A, Kagan, Valerian, Liu, Yu-Feng, Fu, Shu-Yu, Ye, Qing-Jian, Zhou, Yan-Hong, Wei, Lai, Gabrilovich, Dmitry I, Zhou, Jie

“…Myeloid-derived suppressor cells are induced in newborn mice by breast-milk-derived lactoferrin and confer protection in a model of necrotizing enterocolitis…”
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Unique pattern of neutrophil migration and function during tumor progression Autor Patel, Sima, Fu, Shuyu, Mastio, Jerome, Dominguez, George A., Purohit, Abhilasha, Kossenkov, Andrew, Lin, Cindy, Alicea-Torres, Kevin, Sehgal, Mohit, Nefedova, Yulia, Zhou, Jie, Languino, Lucia R., Clendenin, Cynthia, Vonderheide, Robert H., Mulligan, Charles, Nam, Brian, Hockstein, Neil, Masters, Gregory, Guarino, Michael, Schug, Zachary T., Altieri, Dario C, Gabrilovich, Dmitry I.

“…Although neutrophils have been linked to the formation of the pre-metastatic niche, the mechanism of their migration to distant, uninvolved tissues has…”
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A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression Autor Deng, Hui, Lin, Cindy, Garcia-Gerique, Laura, Fu, Shuyu, Cruz, Zachary, Bonner, Erin E, Rosenwasser, Matthew, Rajagopal, Sridharan, Sadhu, M Naveen, Gajendran, Chandru, Zainuddin, Mohd, Gosu, Ramachandraiah, Sivanandhan, Dhanalakshmi, Shelef, Miriam A, Nam, Brian, Vogl, Dan T, Gabrilovich, Dmitry I, Nefedova, Yulia

“…Neutrophils are closely involved in the regulation of tumor progression and formation of premetastatic niches. However, the mechanisms of their involvement and…”
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The lexical apparatus of users’ discussions about conflict in the Internet space: The experience of empirical research Autor Yulia Nefedova, Maria Anikina

“…The paper presents the experience of empirical study of lexical characteristics of mass communication texts (users’ comments) in various Telegram channels…”
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Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer Autor Kwak, Taekyoung, Wang, Fang, Deng, Hui, Condamine, Thomas, Kumar, Vinit, Perego, Michela, Kossenkov, Andrew, Montaner, Luis J., Xu, Xiaowei, Xu, Wei, Zheng, Cathy, Schuchter, Lynn M., Amaravadi, Ravi K., Mitchell, Tara C., Karakousis, Giorgos C., Mulligan, Charles, Nam, Brian, Masters, Gregory, Hockstein, Neil, Bennett, Joseph, Nefedova, Yulia, Gabrilovich, Dmitry I.

“…Here, we report that functional heterogeneity of macrophages in cancer could be determined by the nature of their precursors: monocytes (Mons) and monocytic…”
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Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer Autor Youn, Je-In, Kumar, Vinit, Collazo, Michelle, Nefedova, Yulia, Condamine, Thomas, Cheng, Pingyan, Villagra, Alejandro, Antonia, Scott, McCaffrey, Judith C, Fishman, Mayer, Sarnaik, Amod, Horna, Pedro, Sotomayor, Eduardo, Gabrilovich, Dmitry I

“…Gabrilovich and colleagues show that monocytic myeloid-derived suppressor cells (MDSCs) differentiate into polymorphonuclear MDSCs in individuals with tumors,…”
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Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs Autor Mastio, Jérôme, Condamine, Thomas, Dominguez, George, Kossenkov, Andrew V, Donthireddy, Laxminarasimha, Veglia, Filippo, Lin, Cindy, Wang, Fang, Fu, Shuyu, Zhou, Jie, Viatour, Patrick, Lavilla-Alonso, Sergio, Polo, Alexander T, Tcyganov, Evgenii N, Mulligan, Jr, Charles, Nam, Brian, Bennett, Joseph, Masters, Gregory, Guarino, Michael, Kumar, Amit, Nefedova, Yulia, Vonderheide, Robert H, Languino, Lucia R, Abrams, Scott I, Gabrilovich, Dmitry I

“…We have identified a precursor that differentiates into granulocytes in vitro and in vivo yet belongs to the monocytic lineage. We have termed these cells…”
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Intercellular hif1α reprograms mammary progenitors and myeloid immune evasion to drive high-risk breast lesions Autor Bertolini, Irene, Perego, Michela, Nefedova, Yulia, Lin, Cindy, Milcarek, Andrew, Vogel, Peter, Ghosh, Jagadish C., Kossenkov, Andrew V., Altieri, Dario C.

“…The origin of breast cancer, whether primary or recurrent, is unknown. Here, we show that invasive breast cancer cells exposed to hypoxia release small…”
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Bone marrow PMN-MDSCs and neutrophils are functionally similar in protection of multiple myeloma from chemotherapy Autor Ramachandran, Indu R., Condamine, Thomas, Lin, Cindy, Herlihy, Sarah E., Garfall, Alfred, Vogl, Dan T., Gabrilovich, Dmitry I., Nefedova, Yulia

“…•Myeloid cells play a critical role in regulation of myeloma growth.•PMN-MDSCs and neutrophils equally protect myeloma cells from chemotherapy.•PMN-MDSCs and…”
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Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo Autor Tyurina, Yulia Y., Kapralov, Alexandr A., Tyurin, Vladimir A., Shurin, Galina, Amoscato, Andrew A., Rajasundaram, Dhivyaa, Tian, Hua, Bunimovich, Yuri L., Nefedova, Yulia, Herrick, William G., Parchment, Ralph E., Doroshow, James H., Bayir, Hulya, Srivastava, Apurva K., Kagan, Valerian E.

“…Growing cancer cells effectively evade most programs of regulated cell death, particularly apoptosis. This necessitates a search for alternative therapeutic…”
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Canonical Wnt Pathway Inhibitor ICG-001 Induces Cytotoxicity of Multiple Myeloma Cells in Wnt-Independent Manner Autor Grigson, Eileen R., Ozerova, Maria, Pisklakova, Alexandra, Liu, Hao, Sullivan, Daniel M., Nefedova, Yulia

“…Canonical Wnt signaling has been implicated in the regulation of multiple myeloma (MM) growth. Here, we investigated whether the targeting of this pathway with…”
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Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy Autor Nefedova, Yulia, Sullivan, Daniel M, Bolick, Sophia C, Dalton, William S, Gabrilovich, Dmitry I

“…Drug resistance remains a critical problem in the treatment of patients with multiple myeloma. Recent studies have determined that Notch signaling plays a…”
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Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway Autor Nefedova, Yulia, Nagaraj, Srinivas, Rosenbauer, Amsler, Muro-Cacho, Carlos, Sebti, Said M, Gabrilovich, Dmitry I

“…Abnormal dendritic cell differentiation and accumulation of immunosuppressive myeloid cells in cancer is one of the major factors of tumor nonresponsiveness…”
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975 Activation of myeloid cells by β-glucan clears disseminating ovarian cancer cells from the peritoneal fluid through macrophage-mediated clotting and omentum neutrophil extracellular traps Autor Murphy, Brennah, Miyamoto, Taito, Manning, Bryan, Zhang, Rugang, Nefedova, Yulia, Zhang, Nan

“…BackgroundOvarian cancer (OvCa) is the most lethal gynecological cancer and the fifth leading cause of cancer-related deaths in women. Despite an initial…”
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Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer Autor Nefedova, Yulia, Huang, Mei, Kusmartsev, Sergei, Bhattacharya, Raka, Cheng, Pingyan, Salup, Raoul, Jove, Richard, Gabrilovich, Dmitry

“…Abnormal differentiation of myeloid cells is one of the hallmarks of cancer. However, the molecular mechanisms of this process remain elusive. In this study,…”
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Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines Autor Nefedova, Yulia, Cheng, Pingyan, Alsina, Melissa, Dalton, William S, Gabrilovich, Dmitry I

“…The bone marrow (BM) microenvironment plays a critical role in malignant cell growth, patient survival, and response to chemotherapy in hematologic…”
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