Suchergebnisse - "Nauck, Matthias"

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    Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome von Porcu, Eleonora, Sadler, Marie C., Lepik, Kaido, Auwerx, Chiara, Wood, Andrew R., Weihs, Antoine, Sleiman, Maroun S. Bou, Ribeiro, Diogo M., Bandinelli, Stefania, Tanaka, Toshiko, Nauck, Matthias, Völker, Uwe, Delaneau, Olivier, Metspalu, Andres, Teumer, Alexander, Frayling, Timothy, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán

    ISSN: 2041-1723, 2041-1723
    Veröffentlicht: London Nature Publishing Group UK 24.09.2021
    Veröffentlicht in Nature communications (24.09.2021)
    “… Comparing transcript levels between healthy and diseased individuals allows the identification of differentially expressed genes, which may be causes, …”
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    Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study von Pink, Christiane, Holtfreter, Birte, Völzke, Henry, Nauck, Matthias, Dörr, Marcus, Kocher, Thomas

    ISSN: 1741-7015, 1741-7015
    Veröffentlicht: London BioMed Central 13.11.2023
    Veröffentlicht in BMC medicine (13.11.2023)
    “… Background Recent studies have highlighted the role of low-grade systemic inflammation in linking periodontitis to cardiovascular disease (CVD) outcomes, but …”
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    Das Netzwerk Universitätsmedizin: Technisch-organisatorische Ansätze für Forschungsdatenplattformen von Heyder, Ralf

    ISSN: 1436-9990, 1437-1588
    Veröffentlicht: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2023
    “… Zusammenfassung Das Netzwerk Universitätsmedizin (NUM) besteht aus den 36 Standorten der Universitätsmedizin in Deutschland. Der Auftrag ist die Koordinierung …”
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    Circulating Irisin Concentrations Are Associated with a Favourable Lipid Profile in the General Population von Oelmann, Simon, Nauck, Matthias, Völzke, Henry, Bahls, Martin, Friedrich, Nele

    ISSN: 1932-6203, 1932-6203
    Veröffentlicht: United States Public Library of Science 29.04.2016
    Veröffentlicht in PloS one (29.04.2016)
    “… Irisin is a myokine, which is mainly inversely associated with the risk for non-communicable diseases. Irisin improves cellular energy metabolism by uncoupling …”
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    Methylation of the FKBP5 gene in association with FKBP5 genotypes, childhood maltreatment and depression von Klinger-König, Johanna, Hertel, Johannes, Van der Auwera, Sandra, Frenzel, Stefan, Pfeiffer, Liliane, Waldenberger, Melanie, Golchert, Janine, Teumer, Alexander, Nauck, Matthias, Homuth, Georg, Völzke, Henry, Grabe, Hans J

    ISSN: 0893-133X, 1740-634X, 1740-634X
    Veröffentlicht: England Nature Publishing Group 01.04.2019
    Veröffentlicht in Neuropsychopharmacology (New York, N.Y.) (01.04.2019)
    “… DNA methylation of the FKBP5 gene is assumed to alter FKBP5 expression and hence the synthesis of the FK506 binding protein 51, a central element of a genomic …”
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    Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans von Schlosser, Pascal, Li, Yong, Sekula, Peggy, Raffler, Johannes, Grundner-Culemann, Franziska, Pietzner, Maik, Cheng, Yurong, Wuttke, Matthias, Steinbrenner, Inga, Schultheiss, Ulla T., Kotsis, Fruzsina, Kacprowski, Tim, Forer, Lukas, Hausknecht, Birgit, Ekici, Arif B., Nauck, Matthias, Völker, Uwe, Walz, Gerd, Oefner, Peter J., Kronenberg, Florian, Mohney, Robert P., Köttgen, Michael, Suhre, Karsten, Eckardt, Kai-Uwe, Kastenmüller, Gabi, Köttgen, Anna

    ISSN: 1061-4036, 1546-1718, 1546-1718
    Veröffentlicht: New York Nature Publishing Group US 01.02.2020
    Veröffentlicht in Nature genetics (01.02.2020)
    “… The kidneys integrate information from continuous systemic processes related to the absorption, distribution, metabolism and excretion (ADME) of metabolites …”
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    A metabolome-wide association study in the general population reveals decreased levels of serum laurylcarnitine in people with depression von Zacharias, Helena U, Hertel, Johannes, Johar, Hamimatunnisa, Pietzner, Maik, Lukaschek, Karoline, Atasoy, Seryan, Kunze, Sonja, Völzke, Henry, Nauck, Matthias, Friedrich, Nele, Kastenmüller, Gabi, Grabe, Hans J, Gieger, Christian, Krumsiek, Jan, Ladwig, Karl-Heinz

    ISSN: 1359-4184, 1476-5578, 1476-5578
    Veröffentlicht: England Nature Publishing Group 01.12.2021
    Veröffentlicht in Molecular psychiatry (01.12.2021)
    “… Depression constitutes a leading cause of disability worldwide. Despite extensive research on its interaction with psychobiological factors, associated …”
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    Spatial variation in risk factors for anti-hepatitis E antibody titers in a population-based German study von Díaz, Andrea C., Ittermann, Till, Nauck, Matthias, Petersmann, Astrid, Völzke, Henry, Schauer, Birgit

    ISSN: 2045-2322, 2045-2322
    Veröffentlicht: London Nature Publishing Group UK 21.11.2025
    Veröffentlicht in Scientific reports (21.11.2025)
    “… The transmission of hepatitis E virus (HEV) genotype 3 remains unclear. Up to date, it is predominantly considered a foodborne disease. However, there is …”
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    Comprehensive metabolic profiling of chronic low-grade inflammation among generally healthy individuals von Pietzner, Maik, Kaul, Anne, Henning, Ann-Kristin, Kastenmüller, Gabi, Artati, Anna, Lerch, Markus M., Adamski, Jerzy, Nauck, Matthias, Friedrich, Nele

    ISSN: 1741-7015, 1741-7015
    Veröffentlicht: London BioMed Central 30.11.2017
    Veröffentlicht in BMC medicine (30.11.2017)
    “… Background Inflammation occurs as an immediate protective response of the immune system to a harmful stimulus, whether locally confined or systemic. In …”
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    Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study von Cheng, Yurong, Li, Yong, Scherer, Nora, Grundner-Culemann, Franziska, Lehtimäki, Terho, Mishra, Binisha H., Raitakari, Olli T., Nauck, Matthias, Eckardt, Kai-Uwe, Sekula, Peggy, Schultheiss, Ulla T.

    ISSN: 1553-7404, 1553-7390, 1553-7404
    Veröffentlicht: United States Public Library of Science 06.04.2022
    Veröffentlicht in PLoS genetics (06.04.2022)
    “… Osteopontin (OPN), encoded by SPP1 , is a phosphorylated glycoprotein predominantly synthesized in kidney tissue. Increased OPN mRNA and protein expression …”
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    Gender-specific pathway differences in the human serum metabolome von Krumsiek, Jan, Mittelstrass, Kirstin, Do, Kieu Trinh, Stückler, Ferdinand, Ried, Janina, Adamski, Jerzy, Peters, Annette, Illig, Thomas, Kronenberg, Florian, Friedrich, Nele, Nauck, Matthias, Pietzner, Maik, Mook-Kanamori, Dennis O., Suhre, Karsten, Gieger, Christian, Grallert, Harald, Theis, Fabian J., Kastenmüller, Gabi

    ISSN: 1573-3882, 1573-3890
    Veröffentlicht: New York Springer US 01.12.2015
    Veröffentlicht in Metabolomics (01.12.2015)
    “… The susceptibility for various diseases as well as the response to treatments differ considerably between men and women. As a basis for a gender-specific …”
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    Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma‐glutamyl transpeptidase levels von Haring, Robin, Wallaschofski, Henri, Nauck, Matthias, Dörr, Marcus, Baumeister, Sebastian E., Völzke, Henry

    ISSN: 0270-9139, 1527-3350, 1527-3350
    Veröffentlicht: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.11.2009
    Veröffentlicht in Hepatology (Baltimore, Md.) (01.11.2009)
    “… The aim of the present study was to investigate the association of serum gamma‐glutamyltransferase (GGT) levels with all‐cause mortality and to assess the …”
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    Association between waist circumference and gray matter volume in 2344 individuals from two adult community-based samples von Janowitz, Deborah, Wittfeld, Katharina, Terock, Jan, Freyberger, Harald Jürgen, Hegenscheid, Katrin, Völzke, Henry, Habes, Mohamad, Hosten, Norbert, Friedrich, Nele, Nauck, Matthias, Domanska, Grazyna, Grabe, Hans Jörgen

    ISSN: 1053-8119, 1095-9572, 1095-9572
    Veröffentlicht: United States Elsevier Inc 15.11.2015
    Veröffentlicht in NeuroImage (Orlando, Fla.) (15.11.2015)
    “… We analyzed the putative association between abdominal obesity (measured in waist circumference) and gray matter volume (Study of Health in Pomerania: SHIP-2, …”
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    Association between serum vitamin D concentrations and inflammatory markers in the general adult population von Mellenthin, Liesa, Wallaschofski, Henri, Grotevendt, Anne, Völzke, Henry, Nauck, Matthias, Hannemann, Anke

    ISSN: 0026-0495, 1532-8600, 1532-8600
    Veröffentlicht: New York, NY Elsevier Inc 01.08.2014
    Veröffentlicht in Metabolism, clinical and experimental (01.08.2014)
    “… In recent years links among vitamin D deficiency, inflammation and cardio-metabolic disease were proposed. As information regarding the associations between …”
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    Longitudinal effects of systemic inflammation markers on periodontitis von Pink, Christiane, Kocher, Thomas, Meisel, Peter, Dörr, Marcus, Markus, Marcello R. P., Jablonowski, Lukasz, Grotevendt, Anne, Nauck, Matthias, Holtfreter, Birte

    ISSN: 0303-6979, 1600-051X, 1600-051X
    Veröffentlicht: United States Blackwell Publishing Ltd 01.11.2015
    Veröffentlicht in Journal of clinical periodontology (01.11.2015)
    “… Aim Systemic low‐grade inflammation represents a central hallmark of chronic diseases and has been proposed as the underlying mechanism linking factors like …”
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    Ceramide Remodeling and Risk of Cardiovascular Events and Mortality von Peterson, Linda R., Xanthakis, Vanessa, Duncan, Meredith S., Gross, Stefan, Friedrich, Nele, Völzke, Henry, Felix, Stephan B., Jiang, Hui, Sidhu, Rohini, Nauck, Matthias, Jiang, Xuntian, Ory, Daniel S., Dörr, Marcus, Vasan, Ramachandran S., Schaffer, Jean E.

    ISSN: 2047-9980, 2047-9980
    Veröffentlicht: England John Wiley and Sons Inc 15.05.2018
    Veröffentlicht in Journal of the American Heart Association (15.05.2018)
    “… Background Recent studies suggest that circulating concentrations of specific ceramide species may be associated with coronary risk and mortality. We sought to …”
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