Suchergebnisse - "Natale, Giuseppina"
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Alpha-synuclein in Parkinson’s disease and other synucleinopathies: from overt neurodegeneration back to early synaptic dysfunction
ISSN: 2041-4889, 2041-4889Veröffentlicht: London Nature Publishing Group UK 01.03.2023Veröffentlicht in Cell death & disease (01.03.2023)“… Although the discovery of the critical role of α-synuclein (α-syn) in the pathogenesis of Parkinson’s disease (PD) is now twenty-five years old, it still …”
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Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson’s disease
ISSN: 2041-1723, 2041-1723Veröffentlicht: London Nature Publishing Group UK 02.09.2019Veröffentlicht in Nature communications (02.09.2019)“… Neuroinflammation is one of the hallmarks of Parkinson’s disease (PD) and may contribute to midbrain dopamine (DA) neuron degeneration. Recent studies link …”
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Synaptic Interactions Between Serotonergic and Dopaminergic Systems in Parkinson's Disease
ISSN: 1875-6190, 1875-6190Veröffentlicht: United Arab Emirates 01.01.2025Veröffentlicht in Current neuropharmacology (01.01.2025)“… Since both serotonergic and dopaminergic afferents densely innervate many parts of the central nervous system, intact crosstalk between serotonin (5-HT) and …”
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Serotonin drives striatal synaptic plasticity in a sex-related manner
ISSN: 0969-9961, 1095-953X, 1095-953XVeröffentlicht: United States Elsevier Inc 01.10.2021Veröffentlicht in Neurobiology of disease (01.10.2021)“… Plasticity at corticostriatal synapses is a key substrate for a variety of brain functions – including motor control, learning and reward processing – and is …”
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Effects of uremic toxins on hippocampal synaptic transmission: implication for neurodegeneration in chronic kidney disease
ISSN: 2058-7716, 2058-7716Veröffentlicht: London Nature Publishing Group UK 16.10.2021Veröffentlicht in Cell death discovery (16.10.2021)“… Patients affected by chronic kidney disease (CKD) have an increased risk of developing cognitive impairment. The cause of mental health disorders in CKD and in …”
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Rapamycin, by Inhibiting mTORC1 Signaling, Prevents the Loss of Striatal Bidirectional Synaptic Plasticity in a Rat Model of L-DOPA-Induced Dyskinesia
ISSN: 1663-4365, 1663-4365Veröffentlicht: Lausanne Frontiers Research Foundation 11.08.2020Veröffentlicht in Frontiers in aging neuroscience (11.08.2020)“… Levodopa (L-DOPA) treatment is the main gold-standard therapy for Parkinson’s disease (PD). Besides good antiparkinsonian effects, prolonged use of this drug …”
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Molecular and cellular determinants of L-Dopa-induced dyskinesia in Parkinson’s Disease
ISSN: 2373-8057, 2373-8057Veröffentlicht: London Nature Publishing Group UK 30.11.2024Veröffentlicht in NPJ Parkinson's Disease (30.11.2024)“… Treatment with L-3,4-dihydroxyphenylalanine (L-Dopa) compensates for decreased striatal dopamine (DA) levels and reduces Parkinson’s disease (PD) symptoms …”
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Author Correction: Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson’s disease
ISSN: 2041-1723, 2041-1723Veröffentlicht: London Nature Publishing Group UK 14.10.2019Veröffentlicht in Nature communications (14.10.2019)“… An amendment to this paper has been published and can be accessed via a link at the top of the paper …”
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Reply to: Rewiring Brains in Parkinson's Disease: The New Era of Brain Stimulation
ISSN: 0885-3185, 1531-8257, 1531-8257Veröffentlicht: Hoboken, USA John Wiley & Sons, Inc 01.12.2021Veröffentlicht in Movement disorders (01.12.2021)Volltext
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Rapid response and sustained remission by rituximab in four cases of plasma-exchange-failed acute thrombotic thrombocytopenic purpura
ISSN: 0925-5710, 1865-3774, 1865-3774Veröffentlicht: Tokyo Springer Japan 01.04.2009Veröffentlicht in International journal of hematology (01.04.2009)Volltext
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Astrocyte Responses Influence Local Effects of Whole‐Brain Magnetic Stimulation in Parkinsonian Rats
ISSN: 0885-3185, 1531-8257, 1531-8257Veröffentlicht: Hoboken, USA John Wiley & Sons, Inc 01.12.2023Veröffentlicht in Movement disorders (01.12.2023)“… Background Excessive glutamatergic transmission in the striatum is implicated in Parkinson's disease (PD) progression. Astrocytes maintain glutamate …”
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P030 ASTROCYTE RESPONSES INFLUENCE LOCAL EFFECTS OF WHOLE-BRAIN MAGNETIC STIMULATION IN PARKINSONIAN RATS
ISSN: 1094-7159Veröffentlicht: Elsevier Inc 01.01.2025Veröffentlicht in Neuromodulation (Malden, Mass.) (01.01.2025)Volltext
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Corticostriatal synaptic plasticity alterations in the R6/1 transgenic mouse model of Huntington's disease
ISSN: 0360-4012, 1097-4547, 1097-4547Veröffentlicht: United States Wiley Subscription Services, Inc 01.12.2019Veröffentlicht in Journal of neuroscience research (01.12.2019)“… Huntington's disease (HD) is a genetic neurodegenerative condition characterized by abnormal dopamine (DA)–glutamate interactions, severe alterations in motor …”
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Transcranial Magnetic Stimulation Exerts “Rejuvenation” Effects on Corticostriatal Synapses after Partial Dopamine Depletion
ISSN: 0885-3185, 1531-8257, 1531-8257Veröffentlicht: Hoboken, USA John Wiley & Sons, Inc 01.10.2021Veröffentlicht in Movement disorders (01.10.2021)“… Background In experimental models of Parkinson's disease (PD), different degrees of degeneration to the nigrostriatal pathway produce distinct profiles of …”
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Intensive exercise ameliorates motor and cognitive symptoms in experimental Parkinson’s disease restoring striatal synaptic plasticity
ISSN: 2375-2548, 2375-2548Veröffentlicht: United States American Association for the Advancement of Science 14.07.2023Veröffentlicht in Science advances (14.07.2023)“… Intensive physical activity improves motor functions in patients with Parkinson’s disease (PD) at early stages. However, the mechanisms underlying the …”
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A positive allosteric modulator of mGlu4 receptors restores striatal plasticity in an animal model of l-Dopa-induced dyskinesia
ISSN: 0028-3908, 1873-7064, 1873-7064Veröffentlicht: Elsevier Ltd 01.11.2022Veröffentlicht in Neuropharmacology (01.11.2022)“… By decreasing glutamate transmission, mGlu4 receptor positive allosteric modulators (mGlu4-PAM), in combination with levodopa (l-DOPA) may restore the synergy …”
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Long-Term Shaping of Corticostriatal Synaptic Activity by Acute Fasting
ISSN: 1422-0067, 1661-6596, 1422-0067Veröffentlicht: Switzerland MDPI AG 15.02.2021Veröffentlicht in International journal of molecular sciences (15.02.2021)“… Food restriction is a robust nongenic, nonsurgical and nonpharmacologic intervention known to improve health and extend lifespan in various species. Food is …”
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Dopamine drives binge‐like consumption of a palatable food in experimental Parkinsonism
ISSN: 0885-3185, 1531-8257, 1531-8257Veröffentlicht: Hoboken, USA John Wiley & Sons, Inc 01.06.2019Veröffentlicht in Movement disorders (01.06.2019)“… Background Prolonged dopaminergic replacement therapy in PD results in pulsatile dopamine receptors stimulation in both dorsal and ventral striatum causing …”
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Multicentric myeloid/NK sarcoma in an aleukemic patient evolved in refractory acute leukemia
ISSN: 0145-2126, 1873-5835, 1873-5835Veröffentlicht: England Elsevier Ltd 01.09.2009Veröffentlicht in Leukemia research (01.09.2009)Volltext
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Isolated bone involvement of a single lumbar vertebra body as unusual presentation of relapsing Hodgkin's lymphoma
ISSN: 0284-186X, 1651-226X, 1651-226XVeröffentlicht: England Informa UK Ltd 2009Veröffentlicht in Acta oncologica (2009)Volltext
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