Search Results - "Nadeau, Kari"

Climate Change, Fossil-Fuel Pollution, and Children’s Health by Perera, Frederica, Nadeau, Kari

“…Climate change and air pollution, largely caused by the burning of fossil fuels, pose serious harms to children’s health. Children from communities of color…”
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Effect of air pollution on asthma by Zhou, Xiaoying, Sampath, Vanitha, Nadeau, Kari C

“…Asthma is a chronic inflammatory airway disease characterized by respiratory symptoms, variable airflow obstruction, bronchial hyperresponsiveness, and airway…”
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World Health Organization global air quality guideline recommendations: Executive summary by Goshua, Anna, Akdis, Cezmi A., Nadeau, Kari C.

“…Air pollution is a leading cause of death globally and has resulted in the loss of millions of healthy years of life. Moreover, the health burden has fallen…”
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The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States by Gupta, Ruchi S, Warren, Christopher M, Smith, Bridget M, Blumenstock, Jesse A, Jiang, Jialing, Davis, Matthew M, Nadeau, Kari C

“…: media-1vid110.1542/5840360268001PEDS-VA_2018-1235 BACKGROUND: Childhood food allergy (FA) is a life-threatening chronic condition that substantially impairs…”
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Food allergy: immune mechanisms, diagnosis and immunotherapy by Yu, Wong, Freeland, Deborah M. Hussey, Nadeau, Kari C.

“…Key Points There are many forms of food allergy, the most common of which are IgE mediated. Common IgE-mediated food allergies include those to peanuts, tree…”
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High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes by Croote, Derek, Darmanis, Spyros, Nadeau, Kari C, Quake, Stephen R

“…Immunoglobulin E (IgE) antibodies protect against helminth infections but can also cause life-threatening allergic reactions. Despite their role in human…”
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Food Allergy from Infancy Through Adulthood by Sicherer, Scott H, Warren, Christopher M, Dant, Christopher, Gupta, Ruchi S, Nadeau, Kari C

“…Food allergies are the result of immune responses that cause adverse reactions to foods. Immune responses to foods may produce a spectrum of symptoms and…”
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Advances and novel developments in mechanisms of allergic inflammation by Han, Xiaorui, Krempski, James W., Nadeau, Kari

“…In the past decade, research in the molecular and cellular underpinnings of basic and clinical immunology has significantly advanced our understanding of…”
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Human and planetary health on fire by Akdis, Cezmi A, Nadeau, Kari C

“…Wildfires are increasing globally, with several recent catastrophic wildfires linked to climate change. Here, we consider the negative impact of the toxic…”
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Allergen Specific IgG Antibodies for Cat Allergy? by Nadeau, Kari C

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Fecal microbiome and metabolome differ in healthy and food-allergic twins by Bao, Riyue, Hesser, Lauren A., He, Ziyuan, Zhou, Xiaoying, Nadeau, Kari C., Nagler, Cathryn R.

“…BACKGROUNDThere has been a striking generational increase in the prevalence of food allergies. We have proposed that this increase can be explained, in part,…”
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Distribution of ACE2, CD147, CD26, and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID‐19 risk factors by Radzikowska, Urszula, Ding, Mei, Tan, Ge, Zhakparov, Damir, Peng, Yaqi, Wawrzyniak, Paulina, Wang, Ming, Li, Shuo, Morita, Hideaki, Altunbulakli, Can, Reiger, Matthias, Neumann, Avidan U., Lunjani, Nonhlanhla, Traidl‐Hoffmann, Claudia, Nadeau, Kari C., O’Mahony, Liam, Akdis, Cezmi, Sokolowska, Milena

“…Background Morbidity and mortality from COVID‐19 caused by novel coronavirus SARS‐CoV‐2 is accelerating worldwide, and novel clinical presentations of COVID‐19…”
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Newly identified T cell subsets in mechanistic studies of food immunotherapy by Sampath, Vanitha, Nadeau, Kari C.

“…Allergen-specific immunotherapy has shown promise for the treatment of food allergy and is currently being evaluated in clinical trials. Although immunotherapy…”
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Environmental factors in epithelial barrier dysfunction by Celebi Sözener, Zeynep, Cevhertas, Lacin, Nadeau, Kari, Akdis, Mübeccel, Akdis, Cezmi A.

“…The main interfaces controlling and attempting to homeostatically balance communications between the host and the environment are the epithelial barriers of…”
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Molecular and cellular mechanisms of food allergy and food tolerance by Chinthrajah, R. Sharon, Hernandez, Joseph D., Boyd, Scott D., Galli, Stephen J., Nadeau, Kari C.

“…Ingestion of innocuous antigens, including food proteins, normally results in local and systemic immune nonresponsiveness in a process termed oral tolerance…”
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Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine by Li, Chunfeng, Lee, Audrey, Grigoryan, Lilit, Arunachalam, Prabhu S, Scott, Madeleine K D, Trisal, Meera, Wimmers, Florian, Sanyal, Mrinmoy, Weidenbacher, Payton A, Feng, Yupeng, Adamska, Julia Z, Valore, Erika, Wang, Yanli, Verma, Rohit, Reis, Noah, Dunham, Diane, O'Hara, Ruth, Park, Helen, Luo, Wei, Gitlin, Alexander D, Kim, Peter, Khatri, Purvesh, Nadeau, Kari C, Pulendran, Bali

“…Despite the success of the BNT162b2 mRNA vaccine, the immunological mechanisms that underlie its efficacy are poorly understood. Here we analyzed the innate…”
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Mechanisms of climate change and related air pollution on the immune system leading to allergic disease and asthma by Sampath, Vanitha, Aguilera, Juan, Prunicki, Mary, Nadeau, Kari C.

“…Climate change is considered the greatest threat to global health. Greenhouse gases as well as global surface temperatures have increased causing more frequent…”
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Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19 by Azkur, Ahmet Kursat, Akdis, Mübeccel, Azkur, Dilek, Sokolowska, Milena, Veen, Willem, Brüggen, Marie‐Charlotte, O’Mahony, Liam, Gao, Yadong, Nadeau, Kari, Akdis, Cezmi A.

“…As a zoonotic disease that has already spread globally to several million human beings and possibly to domestic and wild animals, eradication of coronavirus…”
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Climate change: A call to action for the United Nations by Nadeau, Kari C., Agache, Ioana, Jutel, Marek, Annesi Maesano, Isabella, Akdis, Mübeccel, Sampath, Vanitha, D'Amato, Gennaro, Cecchi, Lorenzo, Traidl‐Hoffmann, Claudia, Akdis, Cezmi A.

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Pyroptosis, gasdermins and allergic diseases by Panganiban, Ronald Allan, Nadeau, Kari C., Lu, Quan

“…Pyroptosis is an inflammatory form of programmed cell death that is distinct from necrosis and apoptosis. Pyroptosis is primarily mediated by the gasdermin…”
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