Suchergebnisse - "Mutlu, Merve"
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Small molecule induced STING degradation facilitated by the HECT ligase HERC4
ISSN: 2041-1723, 2041-1723Veröffentlicht: London Nature Publishing Group UK 29.05.2024Veröffentlicht in Nature communications (29.05.2024)“… Stimulator of interferon genes (STING) is a central component of the cytosolic nucleic acids sensing pathway and as such master regulator of the type I …”
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Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
ISSN: 2211-1247, 2211-1247Veröffentlicht: United States Elsevier Inc 25.08.2020Veröffentlicht in Cell reports (Cambridge) (25.08.2020)“… Using genome-wide radiogenetic profiling, we functionally dissect vulnerabilities of cancer cells to ionizing radiation (IR). We identify ERCC6L2 as a major …”
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3
Plasma Cell Neoplasms of Paranasal Sinuses: Two Case Reports
ISSN: 2602-4837, 2602-4837Veröffentlicht: Istanbul University Press 01.06.2024Veröffentlicht in The turkish journal of ear nose and throat (01.06.2024)“… Sinonasal system malignancies are rare, constituting only 1% of all malignancies and less than 5% of head and neck malignancies. The common form of plasma cell …”
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MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
ISSN: 2211-1247, 2211-1247Veröffentlicht: United States Elsevier Inc 30.05.2023Veröffentlicht in Cell reports (Cambridge) (30.05.2023)“… The PSMC3IP-MND1 heterodimer promotes meiotic D loop formation before DNA strand exchange. In genome-scale CRISPR-Cas9 mutagenesis and interference screens in …”
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Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents
ISSN: 1574-7891, 1878-0261, 1878-0261Veröffentlicht: United States John Wiley & Sons, Inc 01.06.2018Veröffentlicht in Molecular oncology (01.06.2018)“… The absence of biomarkers to accurately predict anticancer therapy response remains a major obstacle in clinical oncology. We applied a genome‐wide …”
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Investigating Pre-Service English Language Teachers‘ Identity Construction: a Narrative Inquiry in the Turkish Context
ISBN: 9798288814655Veröffentlicht: ProQuest Dissertations & Theses 01.01.2025“… This dissertation explores how pre-service English language teachers construct their professional identities during the final year of their teacher education …”
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Dual BACH1 regulation by complementary SCF-type E3 ligases
ISSN: 1097-4172, 1097-4172Veröffentlicht: United States 26.12.2024Veröffentlicht in Cell (26.12.2024)“… Broad-complex, tramtrack, and bric-à-brac domain (BTB) and CNC homolog 1 (BACH1) is a key regulator of the cellular oxidative stress response and an oncogene …”
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miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer
ISSN: 2045-2322, 2045-2322Veröffentlicht: London Nature Publishing Group UK 07.09.2016Veröffentlicht in Scientific reports (07.09.2016)“… Dysregulation of PI3K and MAPK pathways promotes uncontrolled cell proliferation, apoptotic inhibition and metastasis. Individual targeting of these pathways …”
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Malatya Ilinde Yetiştirilen Bazı Kayısı Çeşitlerine Ait Çekirdek Protein Hidrolizatlarının Biyoaktivitelerinin Belirlenmesi
ISBN: 9798297917620Veröffentlicht: ProQuest Dissertations & Theses 01.01.2020“… Bu çalışmada, Hacıhaliloğlu, Hasanbey, Kabaaşı ve Zerdali olmak üzere dört çeşit kayısı çekirdek proteinlerinin biyoaktivitelerinin belirlenmesi amaçlanmıştır …”
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Endoscopic Anatomy and a Safe Surgical Corridor to the Anterior Skull Base
ISSN: 1878-8750, 1878-8769, 1878-8769Veröffentlicht: United States Elsevier Inc 01.01.2021Veröffentlicht in World neurosurgery (01.01.2021)“… We describe the possibility to create precise preoperative planning for endonasal endoscopic approaches to the anterior skull base by overlapping endoscopic …”
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Hanefi Mezhebine Göre Evlenme Ehliyeti ve Çocukların Evlendirilmesi Meselesi (Modern Hukuk Mukayeseli)
ISBN: 9798538173358Veröffentlicht: ProQuest Dissertations & Theses 01.01.2019“… Bu araştırmanın amacı, İslam hukukunda çocukların evlendirilmesinin hukuki dayanağını ortaya koymaktır. Ayrıca bu problemin günümüz hukuk sistemindeki yerini …”
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Heterozygous Deep-Intronic Variants and Deletions in ABCA4 in Persons with Retinal Dystrophies and One Exonic ABCA4 Variant
ISSN: 1059-7794, 1098-1004, 1098-1004Veröffentlicht: United States Blackwell Publishing Ltd 01.01.2015Veröffentlicht in Human mutation (01.01.2015)“… ABSTRACT Variants in ABCA4 are responsible for autosomal‐recessive Stargardt disease and cone‐rod dystrophy. Sequence analysis of ABCA4 exons previously …”
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The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer
ISSN: 1949-2553, 1949-2553Veröffentlicht: United States 02.08.2016Veröffentlicht in Oncotarget (02.08.2016)“… Tumor cells develop drug resistance which leads to recurrence and distant metastasis. MicroRNAs are key regulators of tumor pathogenesis; however, little is …”
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Nose Obstruction Symptom Evaluation Scale Outcomes in Covid 19 Patients in the Turkish Population and Prognostic Factors Affecting the Scale
ISSN: 2602-4837, 2602-4837Veröffentlicht: 31.12.2021Veröffentlicht in The turkish journal of ear nose and throat (31.12.2021)Volltext
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Öğrenci Proje Takımı Oluşturma Amaçlı Bir Karar Destek Sistemi Tasarımı
ISBN: 9798544243526Veröffentlicht: ProQuest Dissertations & Theses 01.01.2019“… Öğrenci proje takımı oluşturma problemi, öğrencilerden ve öğrencilere danışmanlık yapacak öğretim elemanlarından, çeşitli kriterler dikkate alınarak takım …”
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Combinatorial Targeting of PI3K and MAPK Pathways by MIR-564 to Inhibit Proliferation and Invasion in Breast Cancer
ISBN: 9798426861077Veröffentlicht: ProQuest Dissertations & Theses 01.01.2016“… Breast cancer is among most common malignant tumors worldwide and one of the deadliest cancer types among women. Like other cancer types, dysregulation of …”
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İklim Değişikliğine Mekânsal Uyum ve Azaltım Yaklaşımlarında Toprak Ekosistem Servislerinin Rolü
ISSN: 2602-4667, 2602-4667Veröffentlicht: 31.12.2023Veröffentlicht in Resilience (31.12.2023)“… Dünya üzerinde kapladıkları %2’lik bir alanla Dünya nüfusunun yarısından fazlasına ev sahipliği yapan kentsel alanlar, ormansızlaşma ve fosil yakıt kullanımını …”
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Determination of bioactivity of seed protein hydrolysates and amygdalin content for some apricot (Prunus armeniaca L.) varieties grown in Malatya, Turkey
ISSN: 2757-8836, 2757-8836Veröffentlicht: 11.08.2022Veröffentlicht in FOOD ANALYTICA GROUP (11.08.2022)“… In this study, the aim was to determine the bioactivity of seed proteins from different apricot varieties, namely Hacıhaliloğlu (a PDO product protected by the …”
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Mecmu’atü’l- Eşar Süleymaniye Kütüphanesi, Nuri Arlasez Numara 263 (Inceleme-Metin)
ISBN: 9798835590452Veröffentlicht: ProQuest Dissertations & Theses 01.01.2014“… Bu çalışma Süleymaniye Kütüphanesi Nuri Arlasez Koleksiyonu'nda 263 numarada Mecmû'atü'l-Eş'âr adıyla kayıtlı mecmuanın incelenmesi ve transkripsiyonlu …”
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SÜLEYMANİYE KÜTÜPHANESİ NURİ ARLASEZ KOL
ISSN: 2147-8872, 2147-8872Veröffentlicht: 01.01.2014Veröffentlicht in Türük Uluslararası Dil, Edebiyat ve Halkbilimi Araştırmaları Dergisi (01.01.2014)Volltext
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