Suchergebnisse - "Mutlu, Merve"

  1. 1

    Small molecule induced STING degradation facilitated by the HECT ligase HERC4 von Mutlu, Merve, Schmidt, Isabel, Morrison, Andrew I., Goretzki, Benedikt, Freuler, Felix, Begue, Damien, Simic, Oliver, Pythoud, Nicolas, Ahrne, Erik, Kapps, Sandra, Roest, Susan, Bonenfant, Debora, Jeanpierre, Delphine, Tran, Thi-Thanh-Thao, Maher, Rob, An, Shaojian, Rietsch, Amandine, Nigsch, Florian, Hofmann, Andreas, Reece-Hoyes, John, Parker, Christian N., Guerini, Danilo

    ISSN: 2041-1723, 2041-1723
    Veröffentlicht: London Nature Publishing Group UK 29.05.2024
    Veröffentlicht in Nature communications (29.05.2024)
    “… Stimulator of interferon genes (STING) is a central component of the cytosolic nucleic acids sensing pathway and as such master regulator of the type I …”
    Volltext
    Journal Article
  2. 2

    Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining von Francica, Paola, Mutlu, Merve, Blomen, Vincent A., Oliveira, Catarina, Nowicka, Zuzanna, Trenner, Anika, Gerhards, Nora M., Bouwman, Peter, Stickel, Elmer, Hekkelman, Maarten L., Lingg, Lea, Klebic, Ismar, van de Ven, Marieke, de Korte-Grimmerink, Renske, Howald, Denise, Jonkers, Jos, Sartori, Alessandro A., Fendler, Wojciech, Chapman, J. Ross, Brummelkamp, Thijn, Rottenberg, Sven

    ISSN: 2211-1247, 2211-1247
    Veröffentlicht: United States Elsevier Inc 25.08.2020
    Veröffentlicht in Cell reports (Cambridge) (25.08.2020)
    “… Using genome-wide radiogenetic profiling, we functionally dissect vulnerabilities of cancer cells to ionizing radiation (IR). We identify ERCC6L2 as a major …”
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    Journal Article
  3. 3

    Plasma Cell Neoplasms of Paranasal Sinuses: Two Case Reports von Mutlu, Merve, Arslan, Hande, Özdemir, Doğukan, Mehel, Dursun, Akgül, Gökhan

    ISSN: 2602-4837, 2602-4837
    Veröffentlicht: Istanbul University Press 01.06.2024
    Veröffentlicht in The turkish journal of ear nose and throat (01.06.2024)
    “… Sinonasal system malignancies are rare, constituting only 1% of all malignancies and less than 5% of head and neck malignancies. The common form of plasma cell …”
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    Journal Article
  4. 4

    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells von Zelceski, Anabel, Francica, Paola, Lingg, Lea, Mutlu, Merve, Stok, Colin, Liptay, Martin, Alexander, John, Baxter, Joseph S., Brough, Rachel, Gulati, Aditi, Haider, Syed, Raghunandan, Maya, Song, Feifei, Sridhar, Sandhya, Forment, Josep V., O’Connor, Mark J., Davies, Barry R., van Vugt, Marcel A.T.M., Krastev, Dragomir B., Pettitt, Stephen J., Tutt, Andrew N.J., Rottenberg, Sven, Lord, Christopher J.

    ISSN: 2211-1247, 2211-1247
    Veröffentlicht: United States Elsevier Inc 30.05.2023
    Veröffentlicht in Cell reports (Cambridge) (30.05.2023)
    “… The PSMC3IP-MND1 heterodimer promotes meiotic D loop formation before DNA strand exchange. In genome-scale CRISPR-Cas9 mutagenesis and interference screens in …”
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    Journal Article
  5. 5

    Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents von Gerhards, Nora M., Blomen, Vincent A., Mutlu, Merve, Nieuwenhuis, Joppe, Howald, Denise, Guyader, Charlotte, Jonkers, Jos, Brummelkamp, Thijn R., Rottenberg, Sven

    ISSN: 1574-7891, 1878-0261, 1878-0261
    Veröffentlicht: United States John Wiley & Sons, Inc 01.06.2018
    Veröffentlicht in Molecular oncology (01.06.2018)
    “… The absence of biomarkers to accurately predict anticancer therapy response remains a major obstacle in clinical oncology. We applied a genome‐wide …”
    Volltext
    Journal Article
  6. 6

    Investigating Pre-Service English Language Teachers‘ Identity Construction: a Narrative Inquiry in the Turkish Context von Mutlu, Merve

    ISBN: 9798288814655
    Veröffentlicht: ProQuest Dissertations & Theses 01.01.2025
    “… This dissertation explores how pre-service English language teachers construct their professional identities during the final year of their teacher education …”
    Volltext
    Dissertation
  7. 7

    Dual BACH1 regulation by complementary SCF-type E3 ligases von Goretzki, Benedikt, Khoshouei, Maryam, Schröder, Martin, Penner, Patrick, Egger, Luca, Stephan, Christine, Argoti, Dayana, Dierlamm, Nele, Rada, Jimena Maria, Kapps, Sandra, Müller, Catrin Swantje, Thiel, Zacharias, Mutlu, Merve, Tschopp, Claude, Furkert, David, Freuler, Felix, Haenni, Simon, Tenaillon, Laurent, Knapp, Britta, Hinniger, Alexandra, Hoppe, Philipp, Schmidt, Enrico, Gutmann, Sascha, Iurlaro, Mario, Ryzhakov, Grigory, Fernández, César

    ISSN: 1097-4172, 1097-4172
    Veröffentlicht: United States 26.12.2024
    Veröffentlicht in Cell (26.12.2024)
    “… Broad-complex, tramtrack, and bric-à-brac domain (BTB) and CNC homolog 1 (BACH1) is a key regulator of the cellular oxidative stress response and an oncogene …”
    Weitere Angaben
    Journal Article
  8. 8

    miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer von Mutlu, Merve, Saatci, Özge, Ansari, Suhail A., Yurdusev, Emre, Shehwana, Huma, Konu, Özlen, Raza, Umar, Şahin, Özgür

    ISSN: 2045-2322, 2045-2322
    Veröffentlicht: London Nature Publishing Group UK 07.09.2016
    Veröffentlicht in Scientific reports (07.09.2016)
    “… Dysregulation of PI3K and MAPK pathways promotes uncontrolled cell proliferation, apoptotic inhibition and metastasis. Individual targeting of these pathways …”
    Volltext
    Journal Article
  9. 9

    Malatya Ilinde Yetiştirilen Bazı Kayısı Çeşitlerine Ait Çekirdek Protein Hidrolizatlarının Biyoaktivitelerinin Belirlenmesi von Mutlu, Merve

    ISBN: 9798297917620
    Veröffentlicht: ProQuest Dissertations & Theses 01.01.2020
    “… Bu çalışmada, Hacıhaliloğlu, Hasanbey, Kabaaşı ve Zerdali olmak üzere dört çeşit kayısı çekirdek proteinlerinin biyoaktivitelerinin belirlenmesi amaçlanmıştır …”
    Volltext
    Dissertation
  10. 10

    Endoscopic Anatomy and a Safe Surgical Corridor to the Anterior Skull Base von Kilinc, Mustafa Cemil, Basak, Hazan, Çoruh, Ayşegul Gürsoy, Mutlu, Merve, Guler, Tugba Morali, Beton, Suha, Comert, Ayhan, Kahilogullari, Gokmen

    ISSN: 1878-8750, 1878-8769, 1878-8769
    Veröffentlicht: United States Elsevier Inc 01.01.2021
    Veröffentlicht in World neurosurgery (01.01.2021)
    “… We describe the possibility to create precise preoperative planning for endonasal endoscopic approaches to the anterior skull base by overlapping endoscopic …”
    Volltext
    Journal Article
  11. 11

    Hanefi Mezhebine Göre Evlenme Ehliyeti ve Çocukların Evlendirilmesi Meselesi (Modern Hukuk Mukayeseli) von Mutlu, Merve

    ISBN: 9798538173358
    Veröffentlicht: ProQuest Dissertations & Theses 01.01.2019
    “… Bu araştırmanın amacı, İslam hukukunda çocukların evlendirilmesinin hukuki dayanağını ortaya koymaktır. Ayrıca bu problemin günümüz hukuk sistemindeki yerini …”
    Volltext
    Dissertation
  12. 12

    Heterozygous Deep-Intronic Variants and Deletions in ABCA4 in Persons with Retinal Dystrophies and One Exonic ABCA4 Variant von Bax, Nathalie M., Sangermano, Riccardo, Roosing, Susanne, Thiadens, Alberta A.H.J., Hoefsloot, Lies H., van den Born, L. Ingeborgh, Phan, Milan, Klevering, B. Jeroen, Westeneng-van Haaften, Carla, Braun, Terry A., Zonneveld-Vrieling, Marijke N., de Wijs, Ilse, Mutlu, Merve, Stone, Edwin M., den Hollander, Anneke I., Klaver, Caroline C.W., Hoyng, Carel B., Cremers, Frans P.M.

    ISSN: 1059-7794, 1098-1004, 1098-1004
    Veröffentlicht: United States Blackwell Publishing Ltd 01.01.2015
    Veröffentlicht in Human mutation (01.01.2015)
    “… ABSTRACT Variants in ABCA4 are responsible for autosomal‐recessive Stargardt disease and cone‐rod dystrophy. Sequence analysis of ABCA4 exons previously …”
    Volltext
    Journal Article
  13. 13

    The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer von Raza, Umar, Saatci, Özge, Uhlmann, Stefan, Ansari, Suhail A, Eyüpoğlu, Erol, Yurdusev, Emre, Mutlu, Merve, Ersan, Pelin Gülizar, Altundağ, Mustafa Kadri, Zhang, Jitao David, Doğan, Hayriye Tatlı, Güler, Gülnur, Şahin, Özgür

    ISSN: 1949-2553, 1949-2553
    Veröffentlicht: United States 02.08.2016
    Veröffentlicht in Oncotarget (02.08.2016)
    “… Tumor cells develop drug resistance which leads to recurrence and distant metastasis. MicroRNAs are key regulators of tumor pathogenesis; however, little is …”
    Weitere Angaben
    Journal Article
  14. 14
  15. 15

    Öğrenci Proje Takımı Oluşturma Amaçlı Bir Karar Destek Sistemi Tasarımı von Bağlarbaşı, Merve Mutlu

    ISBN: 9798544243526
    Veröffentlicht: ProQuest Dissertations & Theses 01.01.2019
    “… Öğrenci proje takımı oluşturma problemi, öğrencilerden ve öğrencilere danışmanlık yapacak öğretim elemanlarından, çeşitli kriterler dikkate alınarak takım …”
    Volltext
    Dissertation
  16. 16

    Combinatorial Targeting of PI3K and MAPK Pathways by MIR-564 to Inhibit Proliferation and Invasion in Breast Cancer von Mutlu, Merve

    ISBN: 9798426861077
    Veröffentlicht: ProQuest Dissertations & Theses 01.01.2016
    “… Breast cancer is among most common malignant tumors worldwide and one of the deadliest cancer types among women. Like other cancer types, dysregulation of …”
    Volltext
    Dissertation
  17. 17

    İklim Değişikliğine Mekânsal Uyum ve Azaltım Yaklaşımlarında Toprak Ekosistem Servislerinin Rolü von YILMAZ MUTLU, Merve, TEZER, Azime

    ISSN: 2602-4667, 2602-4667
    Veröffentlicht: 31.12.2023
    Veröffentlicht in Resilience (31.12.2023)
    “… Dünya üzerinde kapladıkları %2’lik bir alanla Dünya nüfusunun yarısından fazlasına ev sahipliği yapan kentsel alanlar, ormansızlaşma ve fosil yakıt kullanımını …”
    Volltext
    Journal Article
  18. 18

    Determination of bioactivity of seed protein hydrolysates and amygdalin content for some apricot (Prunus armeniaca L.) varieties grown in Malatya, Turkey von Mutlu, Merve, Hayaloglu, Ali Adnan

    ISSN: 2757-8836, 2757-8836
    Veröffentlicht: 11.08.2022
    Veröffentlicht in FOOD ANALYTICA GROUP (11.08.2022)
    “… In this study, the aim was to determine the bioactivity of seed proteins from different apricot varieties, namely Hacıhaliloğlu (a PDO product protected by the …”
    Volltext
    Journal Article
  19. 19

    Mecmu’atü’l- Eşar Süleymaniye Kütüphanesi, Nuri Arlasez Numara 263 (Inceleme-Metin) von Mutlu, Merve

    ISBN: 9798835590452
    Veröffentlicht: ProQuest Dissertations & Theses 01.01.2014
    “… Bu çalışma Süleymaniye Kütüphanesi Nuri Arlasez Koleksiyonu'nda 263 numarada Mecmû'atü'l-Eş'âr adıyla kayıtlı mecmuanın incelenmesi ve transkripsiyonlu …”
    Volltext
    Dissertation
  20. 20

    SÜLEYMANİYE KÜTÜPHANESİ NURİ ARLASEZ KOL von Mutlu, Merve

    ISSN: 2147-8872, 2147-8872
    Veröffentlicht: 01.01.2014
    Volltext
    Journal Article