Suchergebnisse - "Munkácsy, Gyöngyi"

Pancancer survival analysis of cancer hallmark genes von Nagy, Ádám, Munkácsy, Gyöngyi, Győrffy, Balázs

“… Cancer hallmark genes are responsible for the most essential phenotypic characteristics of malignant transformation and progression. In this study, our aim was …”
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miRpower: a web-tool to validate survival-associated miRNAs utilizing expression data from 2178 breast cancer patients von Lánczky, András, Nagy, Ádám, Bottai, Giulia, Munkácsy, Gyöngyi, Szabó, András, Santarpia, Libero, Győrffy, Balázs

“… Purpose The proper validation of prognostic biomarkers is an important clinical issue in breast cancer research. MicroRNAs (miRNAs) have emerged as a new class …”
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Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes von Győrffy, Balázs, Bottai, Giulia, Fleischer, Thomas, Munkácsy, Gyöngyi, Budczies, Jan, Paladini, Laura, Børresen‐Dale, Anne‐Lise, Kristensen, Vessela N., Santarpia, Libero

“… DNA methylation has a substantial impact on gene expression, affecting the prognosis of breast cancer (BC) patients dependent on molecular subtypes. In this …”
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In silico evaluation of the immunogenic profile of lung cancers with SMARCA4 genetic alterations von Nieto-Jiménez, Cristina, Garcia-Lorenzo, Esther, Diaz-Tejeiro, Cristina, Paniagua-Herranz, Lucía, Sanvicente, Adrián, Doger, Bernard, Moreno, Irene, Pedregal, Manuel, Bartolomé, Jorge, Manzano, Arancha, Munkácsy, Gyöngyi, Győrffy, Balázs, Pérez-Segura, Pedro, Calvo, Emiliano, Moreno, Victor, Ocana, Alberto

“… Genomic alterations in tumor cells can influence immune response, as has been demonstrated in several tumor types. For instance, mutations in certain genes …”
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Currently favored sampling practices for tumor sequencing can produce optimal results in the clinical setting von Pongor, Lőrinc S., Munkácsy, Gyöngyi, Vereczkey, Ildikó, Pete, Imre, Győrffy, Balázs

“… Tumor heterogeneity is a consequence of clonal evolution, resulting in a fractal-like architecture with spatially separated main clones, sub-clones and …”
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Evaluating individual scientific output normalized to publication age and academic field through the Scientometrics.org project von Győrffy, Balázs, Weltz, Boglárka, Munkácsy, Gyöngyi, Herman, Péter, Szabó, István

“… When evaluating the publication performance of a scientist one has to consider not only the difference in publication norms in different scientific fields, but …”
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TP53 mutation hits energy metabolism and increases glycolysis in breast cancer von Harami-Papp, Hajnalka, Pongor, Lőrinc S, Munkácsy, Gyöngyi, Horváth, Gergő, Nagy, Ádám M, Ambrus, Attila, Hauser, Péter, Szabó, András, Tretter, László, Győrffy, Balázs

“… Promising new hallmarks of cancer is alteration of energy metabolism that involves molecular mechanisms shifting cancer cells to aerobe glycolysis. Our goal …”
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Treatment delay significantly increases mortality in colorectal cancer: a meta-analysis von Ungvari, Zoltan, Fekete, Mónika, Fekete, János Tibor, Lehoczki, Andrea, Buda, Annamaria, Munkácsy, Gyöngyi, Varga, Péter, Ungvari, Anna, Győrffy, Balázs

“… Delaying the initiation of cancer treatment increases the risk of mortality, particularly in colorectal cancer (CRC), which is among the most common and …”
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DUSP4 is associated with increased resistance against anti-HER2 therapy in breast cancer von Menyhart, Otília, Budczies, Jan, Munkácsy, Gyöngyi, Esteva, Francisco J, Szabó, András, Miquel, Teresa Puig, Győrffy, Balázs

“… The majority of patients develop resistance against suppression of HER2-signaling mediated by trastuzumab in HER2 positive breast cancer (BC). HER2 …”
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Exercise and survival benefit in cancer patients: evidence from a comprehensive meta-analysis von Ungvari, Zoltan, Fekete, Mónika, Varga, Péter, Munkácsy, Gyöngyi, Fekete, János Tibor, Lehoczki, Andrea, Buda, Annamaria, Kiss, Csaba, Ungvari, Anna, Győrffy, Balázs

“… Cancer remains a major global health challenge, and growing evidence suggests that physical activity is a key modifiable factor that may improve survival …”
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Impact of adherence to the Mediterranean diet on stroke risk von Ungvari, Zoltan, Fekete, Mónika, Varga, Péter, Fekete, János Tibor, Buda, Annamaria, Szappanos, Ágnes, Lehoczki, Andrea, Mózes, Noémi, Grosso, Giuseppe, Menyhart, Otilia, Munkácsy, Gyöngyi, Tarantini, Stefano, Yabluchanskiy, Andriy, Ungvari, Anna, Győrffy, Balázs

“… Stroke is a leading cause of morbidity and mortality worldwide, and dietary patterns have emerged as a significant modifiable factor in stroke prevention. The …”
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Meta-analysis of gene expression profiles associated with histological classification and survival in 829 ovarian cancer samples von Fekete, Tibor, Rásó, Erzsébet, Pete, Imre, Tegze, Bálint, Liko, István, Munkácsy, Gyöngyi, Sipos, Norbert, Rigó Jr, János, Györffy, Balázs

“… Transcriptomic analysis of global gene expression in ovarian carcinoma can identify dysregulated genes capable to serve as molecular markers for histology …”
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Validation of RNAi Silencing Efficiency Using Gene Array Data shows 18.5% Failure Rate across 429 Independent Experiments von Munkácsy, Gyöngyi, Sztupinszki, Zsófia, Herman, Péter, Bán, Bence, Pénzváltó, Zsófia, Szarvas, Nóra, Győrffy, Balázs

“… No independent cross-validation of success rate for studies utilizing small interfering RNA (siRNA) for gene silencing has been completed before. To assess the …”
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Comparison of scientometric achievements at PhD and scientific output ten years later for 4,790 academic researchers von Gyöngyi Munkácsy, Péter Herman, Balázs Győrffy

“… IntroductionPhD is the highest awarded degree offered by universities in different disciplines. Owners of a PhD can teach at universities, start independent …”
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Therapeutic Potential of Tumor Metabolic Reprogramming in Triple-Negative Breast Cancer von Munkácsy, Gyöngyi, Santarpia, Libero, Győrffy, Balázs

“… Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with clinical features of high metastatic potential, susceptibility to …”
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Proteotranscriptomic Discrimination of Tumor and Normal Tissues in Renal Cell Carcinoma von Bartha, Áron, Darula, Zsuzsanna, Munkácsy, Gyöngyi, Klement, Éva, Nyirády, Péter, Győrffy, Balázs

“… Clear cell renal carcinoma is the most frequent type of kidney cancer, with an increasing incidence rate worldwide. In this research, we used a …”
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The role of the Mediterranean diet in reducing the risk of cognitive impairement, dementia, and Alzheimer’s disease: a meta-analysis von Fekete, Mónika, Varga, Péter, Ungvari, Zoltan, Fekete, János Tibor, Buda, Annamaria, Szappanos, Ágnes, Lehoczki, Andrea, Mózes, Noémi, Grosso, Giuseppe, Godos, Justyna, Menyhart, Otilia, Munkácsy, Gyöngyi, Tarantini, Stefano, Yabluchanskiy, Andriy, Ungvari, Anna, Győrffy, Balázs

“… Age-related cognitive impairment and dementia pose a significant global health, social, and economic challenge. While Alzheimer’s disease (AD) has historically …”
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Comparison of scientometric achievements at PhD and scientific output ten years later for 4,790 academic researchers von Munkácsy, Gyöngyi, Herman, Péter, Győrffy, Balázs

“… Introduction PhD is the highest awarded degree offered by universities in different disciplines. Owners of a PhD can teach at universities, start independent …”
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Harnessing Hyperthermia: Molecular, Cellular, and Immunological Insights for Enhanced Anticancer Therapies von Lukácsi, Szilvia, Munkácsy, Gyöngyi, Győrffy, Balázs

“… Hyperthermia, the raising of tumor temperature (≥39°C), holds great promise as an adjuvant treatment for cancer therapy. This review focuses on 2 key aspects …”
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Exploring immune activation patterns in HER2-low and HER2-ultralow breast cancer subtypes von Munkácsy, Gyöngyi, Santarpia, Libero, Győrffy, Balázs

“… Abstract Background A deeper understanding of the molecular and clinical characteristics of HER2-low and ultralow breast cancer (BC) subtypes is essential for …”
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