Suchergebnisse - "Mitchell, Gary F"

Aortic stiffness, pressure and flow pulsatility, and target organ damage von Mitchell, Gary F

“… Measures of aortic stiffness and pressure and flow pulsatility have emerged as correlates of and potential contributors to cardiovascular disease, dementia, …”
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Arterial Stiffness and Cardiovascular Risk in Hypertension von Boutouyrie, Pierre, Chowienczyk, Phil, Humphrey, Jay D, Mitchell, Gary F

“… Arterial stiffness, a leading marker of risk in hypertension, can be measured at material or structural levels, with the latter combining effects of the …”
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Effects of central arterial aging on the structure and function of the peripheral vasculature: implications for end-organ damage von Mitchell, Gary F

“… Over the past decade, numerous studies have shown that increased aortic stiffness is associated with major cardiovascular disease end points, including heart …”
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Uses of Arterial Stiffness in Clinical Practice von Wilkinson, Ian B, Mäki-Petäjä, Kaisa M, Mitchell, Gary F

“… As far back as the ancient Egyptians and Greeks, physicians have observed and interpreted the arterial pulse to diagnose disease. In the last 20 years, …”
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Association of Life's Essential 8 With Cardiovascular Disease and Mortality: The Framingham Heart Study von Rempakos, Athanasios, Prescott, Brenton, Mitchell, Gary F., Vasan, Ramachandran S., Xanthakis, Vanessa

“… The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and …”
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Aortic stiffness, blood pressure progression, and incident hypertension von Kaess, Bernhard M, Rong, Jian, Larson, Martin G, Hamburg, Naomi M, Vita, Joseph A, Levy, Daniel, Benjamin, Emelia J, Vasan, Ramachandran S, Mitchell, Gary F

“… Vascular stiffness increases with advancing age and is a major risk factor for age-related morbidity and mortality. Vascular stiffness and blood pressure …”
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Arterial Stiffness and Diabetes Risk in Framingham Heart Study and UK Biobank von Cohen, Jordana B, Mitchell, Gary F, Gill, Dipender, Burgess, Stephen, Rahman, Mahboob, Hanff, Thomas C, Ramachandran, Vasan S, Mutalik, Karen M, Townsend, Raymond R, Chirinos, Julio A

“… Microvascular damage from large artery stiffness (LAS) in pancreatic, hepatic, and skeletal muscles may affect glucose homeostasis. Our goal was to evaluate …”
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Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility--Reykjavik study von Mitchell, Gary F, van Buchem, Mark A, Sigurdsson, Sigurdur, Gotal, John D, Jonsdottir, Maria K, Kjartansson, Ólafur, Garcia, Melissa, Aspelund, Thor, Harris, Tamara B, Gudnason, Vilmundur, Launer, Lenore J

“… Aortic stiffness increases with age and vascular risk factor exposure and is associated with increased risk for structural and functional abnormalities in the …”
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Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia von Pase, Matthew P, Beiser, Alexa, Himali, Jayandra J, Tsao, Connie, Satizabal, Claudia L, Vasan, Ramachandran S, Seshadri, Sudha, Mitchell, Gary F

“… Aortic stiffening increases the transfers of high pressure and flow pulsatility to small cerebral vessels potentially causing the accumulation of vascular …”
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Blood pressure waveform morphology assessed using a transmission line model and harmonic distortion analysis von Milkovich, Nicholas, Mitchell, Gary F., Suki, Bela, Zhang, Yanhang

“… A major determinant of blood pressure waveform (BPW) morphology is vascular impedance, governed by material properties of the arterial wall and hemodynamics of …”
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Joint influences of obesity, diabetes, and hypertension on indices of ventricular remodeling: Findings from the community-based Framingham Heart Study von von Jeinsen, Beatrice, Vasan, Ramachandran S., McManus, David D., Mitchell, Gary F., Cheng, Susan, Xanthakis, Vanessa

“… Obesity, hypertension, and diabetes are independently associated with cardiac remodeling and frequently co-cluster. The conjoint and separate influences of …”
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Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes von Vasan, Ramachandran S., Short, Meghan I., Niiranen, Teemu J., Xanthakis, Vanessa, DeCarli, Charles, Cheng, Susan, Seshadri, Sudha, Mitchell, Gary F.

“… Background Excess transmission of pressure pulsatility caused by increased arterial stiffness may incur microcirculatory damage in end organs (target organ …”
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Relations of arterial stiffness and endothelial function to brain aging in the community von Tsao, Connie W, Seshadri, Sudha, Beiser, Alexa S, Westwood, Andrew J, Decarli, Charles, Au, Rhoda, Himali, Jayandra J, Hamburg, Naomi M, Vita, Joseph A, Levy, Daniel, Larson, Martin G, Benjamin, Emelia J, Wolf, Philip A, Vasan, Ramachandran S, Mitchell, Gary F

“… To determine the association of arterial stiffness and pressure pulsatility, which can damage small vessels in the brain, with vascular and Alzheimer-type …”
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Cross-Sectional Association of Frailty and Arterial Stiffness in Community-Dwelling Older Adults: The Framingham Heart Study von Orkaby, Ariela R, Lunetta, Kathryn L, Sun, Fangui J, Driver, Jane A, Benjamin, Emelia J, Hamburg, Naomi M, Mitchell, Gary F, Vasan, Ramachandran S, Murabito, Joanne M

“… Frailty is a risk factor for cardiovascular disease (CVD). Underlying mechanisms to explain the connection between frailty and CVD are unclear. We sought to …”
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Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study von Maillard, Pauline, Mitchell, Gary F, Himali, Jayandra J, Beiser, Alexa, Tsao, Connie W, Pase, Matthew P, Satizabal, Claudia L, Vasan, Ramachandran S, Seshadri, Sudha, DeCarli, Charles

“… Previous work from the Framingham Heart Study suggests that brain changes because of arterial aging may begin in young adulthood and that such changes precede …”
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Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study von Hamburg, Naomi M, Keyes, Michelle J, Larson, Martin G, Vasan, Ramachandran S, Schnabel, Renate, Pryde, Moira M, Mitchell, Gary F, Sheffy, Jacob, Vita, Joseph A, Benjamin, Emelia J

“… Digital pulse amplitude augmentation in response to hyperemia is a novel measure of peripheral vasodilator function that depends partially on …”
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Arterial stiffness and wave reflection: Biomarkers of cardiovascular risk von Mitchell, Gary F.

“… Arterial stiffness and excessive pressure pulsatility have emerged as important risk factors for cardiovascular disease. Arterial stiffness increases with age …”
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Arterial Stiffness in Aging: Does It Have a Place in Clinical Practice?: Recent Advances in Hypertension von Mitchell, Gary F

“… Aortic stiffness increases markedly with age and is associated with excess risk for various adverse clinical outcomes, including heart disease, dementia, and …”
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Association of orthostatic blood pressure response with incident heart failure: The Framingham Heart Study von Shrout, Tara A., Pan, Stephanie, Mitchell, Gary F., Vasan, Ramachandran S., Xanthakis, Vanessa

“… Orthostatic hypotension (OH) and hypertension (OHT) are aberrant blood pressure (BP) regulation conditions associated with higher cardiovascular disease risk …”
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Genome-wide association study of blood pressure and hypertension von Levy, Daniel, Ehret, Georg B, Rice, Kenneth, Verwoert, Germaine C, Launer, Lenore J, Dehghan, Abbas, Glazer, Nicole L, Morrison, Alanna C, Johnson, Andrew D, Aspelund, Thor, Aulchenko, Yurii, Lumley, Thomas, Köttgen, Anna, Vasan, Ramachandran S, Rivadeneira, Fernando, Eiriksdottir, Gudny, Guo, Xiuqing, Arking, Dan E, Mitchell, Gary F, Mattace-Raso, Francesco U S, Smith, Albert V, Taylor, Kent, Scharpf, Robert B, Hwang, Shih-Jen, Sijbrands, Eric J G, Bis, Joshua, Harris, Tamara B, Ganesh, Santhi K, O'Donnell, Christopher J, Hofman, Albert, Rotter, Jerome I, Coresh, Josef, Benjamin, Emelia J, Uitterlinden, André G, Heiss, Gerardo, Fox, Caroline S, Witteman, Jacqueline C M, Boerwinkle, Eric, Wang, Thomas J, Gudnason, Vilmundur, Larson, Martin G, Chakravarti, Aravinda, Psaty, Bruce M, van Duijn, Cornelia M

“… Daniel Levy and colleagues report a meta-analysis of genome-wide association studies for blood pressure traits as part of the CHARGE consortium, reporting …”
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