Suchergebnisse - "Mihailov, Evelin"
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The Genetic Legacy of the Expansion of Turkic-Speaking Nomads across Eurasia
ISSN: 1553-7404, 1553-7390, 1553-7404Veröffentlicht: United States Public Library of Science 01.04.2015Veröffentlicht in PLoS genetics (01.04.2015)“… The Turkic peoples represent a diverse collection of ethnic groups defined by the Turkic languages. These groups have dispersed across a vast area, including …”
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Copy number variations and cognitive phenotypes in unselected populations
ISSN: 1538-3598, 1538-3598Veröffentlicht: United States 26.05.2015Veröffentlicht in JAMA : the journal of the American Medical Association (26.05.2015)“… The association of copy number variations (CNVs), differing numbers of copies of genetic sequence at locations in the genome, with phenotypes such as …”
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Demographic associations for autoantibodies in disease-free individuals of a European population
ISSN: 2045-2322, 2045-2322Veröffentlicht: London Nature Publishing Group UK 28.03.2017Veröffentlicht in Scientific reports (28.03.2017)“… The presence of autoantibodies usually precedes autoimmune disease, but is sometimes considered an incidental finding with no clinical relevance. The …”
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Mapping the Genetic Architecture of Gene Regulation in Whole Blood
ISSN: 1932-6203, 1932-6203Veröffentlicht: United States Public Library of Science 01.04.2014Veröffentlicht in PloS one (01.04.2014)“… We aimed to assess whether whole blood expression quantitative trait loci (eQTLs) with effects in cis and trans are robust and can be used to identify …”
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Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
ISSN: 1061-4036, 1546-1718, 1546-1718Veröffentlicht: New York Nature Publishing Group US 01.04.2022Veröffentlicht in Nature genetics (01.04.2022)“… We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately …”
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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
ISSN: 1061-4036, 1546-1718, 1546-1718Veröffentlicht: New York Nature Publishing Group US 01.05.2018Veröffentlicht in Nature genetics (01.05.2018)“… Major depressive disorder (MDD) is a common illness accompanied by considerable morbidity, mortality, costs, and heightened risk of suicide. We conducted a …”
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Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study
ISSN: 2168-6238, 2168-6238Veröffentlicht: United States 01.04.2019Veröffentlicht in JAMA psychiatry (Chicago, Ill.) (01.04.2019)“… Increasing evidence shows that physical activity is associated with reduced risk for depression, pointing to a potential modifiable target for prevention …”
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A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
ISSN: 1061-4036, 1546-1718, 1546-1718Veröffentlicht: New York Nature Publishing Group US 01.10.2015Veröffentlicht in Nature genetics (01.10.2015)“… Hugh Watkins, Sekar Kathiresan, Ruth McPherson, Martin Farrall and colleagues report the results of a large genome-wide association meta-analysis of coronary …”
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Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error
ISSN: 1061-4036, 1546-1718, 1546-1718Veröffentlicht: New York Nature Publishing Group US 01.06.2018Veröffentlicht in Nature genetics (01.06.2018)“… Refractive errors, including myopia, are the most frequent eye disorders worldwide and an increasingly common cause of blindness. This genome-wide association …”
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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
ISSN: 2041-1723, 2041-1723Veröffentlicht: London Nature Publishing Group UK 23.03.2016Veröffentlicht in Nature communications (23.03.2016)“… Genome-wide association studies have identified numerous loci linked with complex diseases, for which the molecular mechanisms remain largely unclear …”
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Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
ISSN: 1061-4036, 1546-1718, 1546-1718Veröffentlicht: New York Nature Publishing Group US 01.06.2016Veröffentlicht in IDEAS Working Paper Series from RePEc (01.06.2016)“… Daniel Benjamin, Meike Bartels, Philipp Koellinger and colleagues report a genome-wide association meta-analysis of subjective well-being, depressive symptoms …”
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Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease
ISSN: 0028-4793, 1533-4406, 1533-4406Veröffentlicht: United States Massachusetts Medical Society 24.03.2016Veröffentlicht in The New England journal of medicine (24.03.2016)“… Searching for genes in which loss-of-function mutations confer protection against disease is a strategy to identity drug targets. This study reports an …”
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Genomic analyses inform on migration events during the peopling of Eurasia
ISSN: 0028-0836, 1476-4687, 1476-4687Veröffentlicht: London Nature Publishing Group UK 13.10.2016Veröffentlicht in Nature (London) (13.10.2016)“… Whole-genome sequencing of individuals from 125 populations provides insight into patterns of genetic diversity, natural selection and human demographic …”
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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
ISSN: 1359-4184, 1476-5578, 1476-5578Veröffentlicht: England Nature Publishing Group 01.07.2020Veröffentlicht in Molecular psychiatry (01.07.2020)“… Depression is more frequent among individuals exposed to traumatic events. Both trauma exposure and depression are heritable. However, the relationship between …”
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Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
ISSN: 1061-4036, 1546-1718Veröffentlicht: New York Nature Publishing Group US 01.08.2016Veröffentlicht in Nature genetics (01.08.2016)“… Aarno Palotie and colleagues present results of a large genome-wide association study of migraine. They identified significant associations at 38 distinct loci …”
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Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection
ISSN: 1558-3597, 1558-3597Veröffentlicht: United States 08.01.2019Veröffentlicht in Journal of the American College of Cardiology (08.01.2019)“… Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndromes (ACS) afflicting predominantly younger to …”
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Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
ISSN: 1061-4036, 1546-1718, 1546-1718Veröffentlicht: New York Nature Publishing Group US 01.11.2015Veröffentlicht in Nature genetics (01.11.2015)“… John Perry and colleagues report the results of a large genome-wide association study meta-analysis to identify variants influencing age at natural menopause …”
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Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
ISSN: 1061-4036, 1546-1718, 1546-1718Veröffentlicht: New York Nature Publishing Group US 01.10.2016Veröffentlicht in Nature genetics (01.10.2016)“… Patricia Munroe, Joanna Howson and colleagues genotype ∼350,000 individuals and identify 30 new blood pressure– or hypertension-associated risk loci. Their …”
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A recent bottleneck of Y chromosome diversity coincides with a global change in culture
ISSN: 1549-5469, 1549-5469Veröffentlicht: United States 01.04.2015Veröffentlicht in Genome research (01.04.2015)“… It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya) …”
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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci
ISSN: 1359-4184, 1476-5578, 1476-5578Veröffentlicht: England Nature Publishing Group 01.10.2020Veröffentlicht in Molecular psychiatry (01.10.2020)“… Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen …”
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