Výsledky vyhledávání - "Metformin/cerebrospinal fluid"

Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide Autor Łabuzek, Krzysztof, Suchy, Dariusz, Gabryel, Bożena, Bielecka, Anna, Liber, Sebastian, Okopień, Bogusław

“…Recently, it has been reported that metformin may attenuate inflammation and directly act on the central nervous system. Using the HPLC method, in Wistar rats,…”
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The effect of metformin on food intake and its potential role in hypothalamic regulation in obese diabetic rats Autor Lv, Wen-shan, Wen, Jun-ping, Li, Li, Sun, Rui-xia, Wang, Jing, Xian, Yu-xin, Cao, Cai-xia, Wang, Yun-long, Gao, Yan-yan

“…Metformin appears to be involved in altering energy expenditure and thermogenesis, and could affect hypothalamic feeding circuits. However, it is not clear…”
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Evaluation of systemic and brain pharmacokinetic parameters for repurposing metformin using intravenous bolus administration Autor Sharma, Sejal, Zhang, Yong, Patel, Dhavalkumar, Akter, Khondker Ayesha, Bagchi, Sounak, Sifat, Ali Ehsan, Nozohouri, Ehsan, Ahn, Yeseul, Karamyan, Vardan T, Bickel, Ulrich, Abbruscato, Thomas J

“…Metformin's potential in treating ischemic stroke and neurodegenerative conditions is of growing interest. Yet, the absence of established systemic and brain…”
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