Search Results - "Metabolites"

Plant Secondary Metabolites: The Weapons for Biotic Stress Management by Al-Khayri, Jameel M., Rashmi, Ramakrishnan, Toppo, Varsha, Chole, Pranjali Bajrang, Banadka, Akshatha, Sudheer, Wudali Narasimha, Nagella, Praveen, Shehata, Wael Fathi, Al-Mssallem, Muneera Qassim, Alessa, Fatima Mohammed, Almaghasla, Mustafa Ibrahim, Rezk, Adel Abdel-Sabour

“…The rise in global temperature also favors the multiplication of pests and pathogens, which calls into question global food security. Plants have developed…”
Get full text

NMR Spectroscopy for Metabolomics Research by Emwas, Abdul-Hamid, Roy, Raja, McKay, Ryan T., Tenori, Leonardo, Saccenti, Edoardo, Gowda, G. A. Nagana, Raftery, Daniel, Alahmari, Fatimah, Jaremko, Lukasz, Jaremko, Mariusz, Wishart, David S.

“…Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the three principal analytical techniques used in metabolomics (the other two…”
Get full text

A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential Avenues of Biocompatible Drug Discovery by Anand, Uttpal, Jacobo-Herrera, Nadia, Altemimi, Ammar, Lakhssassi, Naoufal

“…The war on multidrug resistance (MDR) has resulted in the greatest loss to the world’s economy. Antibiotics, the bedrock, and wonder drug of the 20th century…”
Get full text

MetaboAnalystR 3.0: Toward an Optimized Workflow for Global Metabolomics by Pang, Zhiqiang, Chong, Jasmine, Li, Shuzhao, Xia, Jianguo

“…Liquid chromatography coupled to high-resolution mass spectrometry platforms are increasingly employed to comprehensively measure metabolome changes in systems…”
Get full text

Guide to Metabolomics Analysis: A Bioinformatics Workflow by Chen, Yang, Li, En-Min, Xu, Li-Yan

“…Metabolomics is an emerging field that quantifies numerous metabolites systematically. The key purpose of metabolomics is to identify the metabolites…”
Get full text

Systems Biology and Multi-Omics Integration: Viewpoints from the Metabolomics Research Community by Pinu, Farhana R., Beale, David J., Paten, Amy M., Kouremenos, Konstantinos, Swarup, Sanjay, Schirra, Horst J., Wishart, David

“…The use of multiple omics techniques (i.e., genomics, transcriptomics, proteomics, and metabolomics) is becoming increasingly popular in all facets of life…”
Get full text

Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics by Blaženović, Ivana, Kind, Tobias, Ji, Jian, Fiehn, Oliver

“…The annotation of small molecules remains a major challenge in untargeted mass spectrometry-based metabolomics. We here critically discuss structured…”
Get full text

Cancer Metabolism: The Role of ROS in DNA Damage and Induction of Apoptosis in Cancer Cells by Zhao, Yongxia, Ye, Xiaochun, Xiong, Zhifeng, Ihsan, Awais, Ares, Irma, Martínez, Marta, Lopez-Torres, Bernardo, Martínez-Larrañaga, María-Rosa, Anadón, Arturo, Wang, Xu, Martínez, María-Aránzazu

“…Cancer is a huge challenge for people worldwide. High reactive oxygen species (ROS) levels are a recognized hallmark of cancer and an important aspect of…”
Get full text

Machine Learning Applications for Mass Spectrometry-Based Metabolomics by Liebal, Ulf W., Phan, An N. T., Sudhakar, Malvika, Raman, Karthik, Blank, Lars M.

“…The metabolome of an organism depends on environmental factors and intracellular regulation and provides information about the physiological conditions…”
Get full text

L-Carnitine and Acylcarnitines: Mitochondrial Biomarkers for Precision Medicine by McCann, Marc R., George De la Rosa, Mery Vet, Rosania, Gus R., Stringer, Kathleen A.

“…Biomarker discovery and implementation are at the forefront of the precision medicine movement. Modern advances in the field of metabolomics afford the…”
Get full text

The Effects of Plant-Associated Bacterial Exopolysaccharides on Plant Abiotic Stress Tolerance by Morcillo, Rafael, Manzanera, Maximino

“…Plant growth-promoting rhizobacteria (PGPR) are beneficial soil microorganisms that can stimulate plant growth and increase tolerance to biotic and abiotic…”
Get full text

Glucagon-Like Peptide-1 Receptor Agonists for Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis: An Updated Meta-Analysis of Randomized Controlled Trials by Mantovani, Alessandro, Petracca, Graziana, Beatrice, Giorgia, Csermely, Alessandro, Lonardo, Amedeo, Targher, Giovanni

“…To assess the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for treatment of nonalcoholic fatty liver disease (NAFLD) or steatohepatitis…”
Get full text

Yeast Protein as an Easily Accessible Food Source by Jach, Monika Elżbieta, Serefko, Anna, Ziaja, Maria, Kieliszek, Marek

“…In recent years, the awareness and willingness of consumers to consume healthy food has grown significantly. In order to meet these needs, scientists are…”
Get full text

Glutathione Metabolism in Plants under Stress: Beyond Reactive Oxygen Species Detoxification by Dorion, Sonia, Ouellet, Jasmine C., Rivoal, Jean

“…Glutathione is an essential metabolite for plant life best known for its role in the control of reactive oxygen species (ROS). Glutathione is also involved in…”
Get full text

MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools by Ernst, Madeleine, Kang, Kyo Bin, Caraballo-Rodríguez, Andrés Mauricio, Nothias, Louis-Felix, Wandy, Joe, Chen, Christopher, Wang, Mingxun, Rogers, Simon, Medema, Marnix H., Dorrestein, Pieter C., van der Hooft, Justin J.J.

“…Metabolomics has started to embrace computational approaches for chemical interpretation of large data sets. Yet, metabolite annotation remains a key…”
Get full text

Metabolomics in the Context of Plant Natural Products Research: From Sample Preparation to Metabolite Analysis by Salem, Mohamed A., Perez de Souza, Leonardo, Serag, Ahmed, Fernie, Alisdair R., Farag, Mohamed A., Ezzat, Shahira M., Alseekh, Saleh

“…Plant-derived natural products have long been considered a valuable source of lead compounds for drug development. Natural extracts are usually composed of…”
Get full text

Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target by Behbodikhah, Jennifer, Ahmed, Saba, Elyasi, Ailin, Kasselman, Lora J., De Leon, Joshua, Glass, Amy D., Reiss, Allison B.

“…Apolipoprotein (apo) B, the critical structural protein of the atherogenic lipoproteins, has two major isoforms: apoB48 and apoB100. ApoB48 is found in…”
Get full text

From Nature to Lab: A Review of Secondary Metabolite Biosynthetic Pathways, Environmental Influences, and In Vitro Approaches by Reshi, Zubair Altaf, Ahmad, Waquar, Lukatkin, Alexander S., Javed, Saad Bin

“…Secondary metabolites are gaining an increasing importance in various industries, such as pharmaceuticals, dyes, and food, as is the need for reliable and…”
Get full text

Vitamin D Sources, Metabolism, and Deficiency: Available Compounds and Guidelines for Its Treatment by Dominguez, Ligia J., Farruggia, Mario, Veronese, Nicola, Barbagallo, Mario

“…Studies on vitamin/hormone D deficiency have received a vast amount of attention in recent years, particularly concerning recommendations, guidelines, and…”
Get full text

Antifungal Drugs by Houšť, Jiří, Spížek, Jaroslav, Havlíček, Vladimír

“…We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved…”
Get full text