Suchergebnisse - "Meijers, Joost C M"

An unbalance between von Willebrand factor and ADAMTS13 in acute liver failure: Implications for hemostasis and clinical outcome von Hugenholtz, Greg C. G., Adelmeijer, Jelle, Meijers, Joost C. M., Porte, Robert J., Stravitz, R. Todd, Lisman, Ton

“… Emerging evidence supports the concept of a rebalanced hemostatic state in liver disease as a result of a commensurate decline in prohemostatic and …”
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Differential In Vitro Inhibition of Thrombin Generation by Anticoagulant Drugs in Plasma from Patients with Cirrhosis von Potze, Wilma, Arshad, Freeha, Adelmeijer, Jelle, Blokzijl, Hans, van den Berg, Arie P., Meijers, Joost C. M., Porte, Robert J., Lisman, Ton

“… Treatment and prevention of thrombotic complications is frequently required in patients with cirrhosis. However anticoagulant therapy is often withheld from …”
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Normalization panels for the reliable quantification of circulating microRNAs by RT-qPCR von Kok, Maayke G M, Halliani, Amalia, Moerland, Perry D, Meijers, Joost C M, Creemers, Esther E, Pinto-Sietsma, Sara-Joan

“… Circulating microRNAs (miRNAs) have been reported as biomarkers for disease diagnosis. RT-qPCR is most commonly used to detect miRNAs; however, no consensus on …”
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Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk von Zhang, Hong, Löwenberg, Ester C, Crosby, Jeffrey R, MacLeod, A Robert, Zhao, Chenguang, Gao, Dacao, Black, Chris, Revenko, Alexey S, Meijers, Joost C M, Stroes, Erik S, Levi, Marcel, Monia, Brett P

“… Existing anticoagulants effectively inhibit the activity of coagulation factors of the extrinsic and common pathway but have substantial limitations and can …”
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Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII von Doggen, Carine J M, Rosendaal, Frits R, Meijers, Joost C M

“… The role of the intrinsic coagulation system on the risk of myocardial infarction is unclear. In the Study of Myocardial Infarctions Leiden (SMILE) that …”
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Whole exome sequencing in thrombophilic pedigrees to identify genetic risk factors for venous thromboembolism von Cunha, Marisa L. R., Meijers, Joost C. M., Rosendaal, Frits R., Vlieg, Astrid van Hylckama, Reitsma, Pieter H., Middeldorp, Saskia

“… Family studies have shown a strong heritability component for venous thromboembolism (VTE), but established genetic risk factors are present in only half of …”
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Proteomic analysis of high-density lipoprotein von Rezaee, Farhad, Casetta, Bruno, Levels, J. Han M., Speijer, Dave, Meijers, Joost C. M.

“… Plasma lipoproteins, such as high‐density lipoprotein (HDL), can serve as carriers for a wide range of proteins that are involved in processes such as lipid …”
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Identification and Characterization of Ixodes scapularis Antigens That Elicit Tick Immunity Using Yeast Surface Display von Schuijt, Tim J., Narasimhan, Sukanya, Daffre, Sirlei, DePonte, Kathleen, Hovius, Joppe W. R., Veer, Cornelis van't, van der Poll, Tom, Bakhtiari, Kamran, Meijers, Joost C. M., Boder, Eric T., van Dam, Alje P., Fikrig, Erol

“… Repeated exposure of rabbits and other animals to ticks results in acquired resistance or immunity to subsequent tick bites and is partially elicited by …”
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Platelets in Patients with Premature Coronary Artery Disease Exhibit Upregulation of miRNA340 and miRNA624 von Sondermeijer, Brigitte M., Bakker, Annemieke, Halliani, Amalia, de Ronde, Maurice W. J., Marquart, Arnoud A., Tijsen, Anke J., Mulders, Ties A., Kok, Maayke G. M., Battjes, Suzanne, Maiwald, Steffi, Sivapalaratnam, Suthesh, Trip, Mieke D., Moerland, Perry D., Meijers, Joost C. M., Creemers, Esther E., Pinto-Sietsma, Sara-Joan

“… Coronary artery disease (CAD) is the leading cause of human morbidity and mortality worldwide, underscoring the need to improve diagnostic strategies …”
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Effect of transfusion of fresh frozen plasma on parameters of endothelial condition and inflammatory status in non-bleeding critically ill patients: a prospective substudy of a randomized trial von Straat, Marleen, Müller, Marcella CA, Meijers, Joost CM, Arbous, Mendi S, Spoelstra - de Man, Angelique ME, Beurskens, Charlotte JP, Vroom, Margreeth B, Juffermans, Nicole P

“… Introduction Much controversy exists on the effect of a fresh frozen plasma (FFP) transfusion on systemic inflammation and endothelial damage. Adverse effects …”
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The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia von van Zoelen, Marieke A D, Schouten, Marcel, de Vos, Alex F, Florquin, Sandrine, Meijers, Joost C M, Nawroth, Peter P, Bierhaus, Angelika, van der Poll, Tom

“… Streptococcus pneumoniae is the most common cause of community-acquired pneumonia. The receptor for advanced glycation end products (RAGE) is a multiligand …”
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Correction: Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis von Birnie, Emma, Koh, Gavin C. K. W., Löwenberg, Ester C., Meijers, Joost C. M., Maude, Rapeephan R., Day, Nicholas P. J., Peacock, Sharon J., van der Poll, Tom, Wiersinga, W. Joost

“… [This corrects the article DOI: 10.1371/journal.pntd.0005468.].[This corrects the article DOI: 10.1371/journal.pntd.0005468.] …”
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Vascular Endothelial Growth Factor in the Circulation in Cancer Patients May Not Be a Relevant Biomarker von Niers, Tatjana M. H., Richel, Dick J., Meijers, Joost C. M., Schlingemann, Reinier O.

“… Levels of circulating vascular endothelial growth factor (VEGF) have widely been used as biomarker for angiogenic activity in cancer. For this purpose, …”
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Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) Deficient Mice Are Susceptible to Intracerebral Thrombosis and Ischemic Stroke von Kraft, Peter, Schwarz, Tobias, Meijers, Joost C. M., Stoll, Guido, Kleinschnitz, Christoph

“… Thrombus formation is a key step in the pathophysiology of acute ischemic stroke and results from the activation of the coagulation cascade. Thrombin plays a …”
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Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia von de Kruif, Martijn D, Lemaire, Lucienne C, Giebelen, Ida A, van Zoelen, Marieke A D, Pater, Jennie M, van den Pangaart, Petra S, Groot, Angelique P, de Vos, Alex F, Elliott, Peter J, Meijers, Joost C M, Levi, Marcel, van der Poll, Tom

“… The effects of steroids on the outcome of sepsis are dose dependent. Low doses appear to be beneficial, but high doses do not improve outcome for reasons that …”
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Venous thrombosis risk associated with plasma hypofibrinolysis is explained by elevated plasma levels of TAFI and PAI-1 von Meltzer, Mirjam E, Lisman, Ton, de Groot, Philip G, Meijers, Joost C M, le Cessie, Saskia, Doggen, Carine J M, Rosendaal, Frits R

“… Elevated plasma clot lysis time (CLT) increases risk of venous and arterial thrombosis. It is unclear which fibrinolytic factors contribute to thrombosis risk …”
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Individual with Subclinical Atherosclerosis Have Impaired Proliferation of Blood Outgrowth Endothelial Cells, Which Can Be Restored by Statin Therapy von Martin-Ramirez, Javier, Kok, Maayke G. M., Hofman, Menno, Bierings, Ruben, Creemers, Esther E., Meijers, Joost C. M., Voorberg, Jan, Pinto-Sietsma, Sara-Joan

“… To study the regenerative capacity of the endothelium in patients with coronary artery disease (CAD), we cultured blood outgrowth endothelial cells (BOECs) of …”
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Endothelial dysfunction, platelet activation, thrombogenesis and fibrinolysis in patients with hypertensive crisis von van den Born, Bert-Jan H, Löwenberg, Ester C, van der Hoeven, Niels V, de Laat, Bas, Meijers, Joost C M, Levi, Marcel, van Montfrans, Gert A

“… Hypertensive crisis is an extreme phenotype of hypertension and hypertension-related thrombotic complications. This is most evident in patients with …”
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Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis von Birnie, Emma, Koh, Gavin C. K. W., Löwenberg, Ester C., Meijers, Joost C. M., Maude, Rapeephan R., Day, Nicholas P. J., Peacock, Sharon J., Poll, Tom van der, Wiersinga, W. Joost

“… Melioidosis, caused by bioterror treat agent Burkholderia pseudomallei, is an important cause of community-acquired Gram-negative sepsis in Southeast Asia and …”
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Utility of thromboelastography and/or thromboelastometry in adults with sepsis: a systematic review von Müller, Marcella C, Meijers, Joost CM, Vroom, Margreeth B, Juffermans, Nicole P

“… Introduction Coagulation abnormalities are frequent in sepsis. Conventional coagulation assays, however, have several limitations. A surge of interest exists …”
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