Suchergebnisse - "Matrix Metalloproteinase 2 - biosynthesis"

Small Arteries From Old Spontaneously Hypertensive Rats Exhibit Enhanced Endothelium‐Independent Vasodilatory Capacity and Reduced Stiffness von Ramirez‐Perez, Francisco I., Jurrissen, Thomas J., Augenreich, Marc A., Castorena‐Gonzalez, Jorge A., Morales‐Quinones, Mariana, Foote, Christopher A., Nourian, Zahra, Lateef, Olubodun M., Imkaew, Natnicha, Sun, Zhe, Hill, Michael A., Meininger, Gerald A., Padilla, Jaume, Martinez‐Lemus, Luis A.

“… Methods We retrospectively compared the mechanical and structural characteristics of small arteries isolated from older hypertensive and younger normotensive (64.7 ± 2.8 vs. 32.1 ± 1.9 years old) human subjects …”
Volltext

Senescent Fibroblasts Enhance Early Skin Carcinogenic Events via a Paracrine MMP-PAR-1 Axis von Malaquin, Nicolas, Vercamer, Chantal, Bouali, Fatima, Martien, Sébastien, Deruy, Emeric, Wernert, Nicolas, Chwastyniak, Maggy, Pinet, Florence, Abbadie, Corinne, Pourtier, Albin

“… The incidence of carcinoma increases greatly with aging, but the cellular and molecular mechanisms underlying this correlation are only partly known. It is …”
Volltext

The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma von Aparna, Manikkath, Rao, Lakshmi, Kunhikatta, Vijayanarayana, Radhakrishnan, Raghu

“… Aim and objectives To study the expression of MMP‐2 and MMP‐9 in the early stages of tongue squamous cell carcinoma and find the association between their expression and local recurrence, metastasis, and survival rates of the subjects …”
Volltext

Impact of Biomarkers of Inflammation and Extracellular Matrix Turnover on the Outcome of Atrial Fibrillation Ablation: Importance of Matrix Metalloproteinase-2 as a Predictor of Atrial Fibrillation Recurrence von OKUMURA, YASUO, WATANABE, ICHIRO, NAKAI, TOSHIKO, OHKUBO, KIMIE, KOFUNE, TATSUYA, KOFUNE, MASAYOSHI, NAGASHIMA, KOICHI, MANO, HIROAKI, SONODA, KAZUMASA, KASAMAKI, YUJI, HIRAYAMA, ATSUSHI

“… Methods and Results: Subjects were 50 patients who underwent catheter ablation for drug …”
Volltext

Cell Migration Is Regulated by AGE-RAGE Interaction in Human Oral Cancer Cells In Vitro von Ko, Shun-Yao, Ko, Hshin-An, Shieh, Tzong-Ming, Chang, Weng-Cheng, Chen, Hong-I, Chang, Shu-Shing, Lin, I-Hsuan

“… Advanced glycation end products (AGEs) are produced in an irreversible non-enzymatic reaction of carbohydrates and proteins. Patients with diabetes mellitus …”
Volltext

Norcantharidin enhances TIMP-2 anti-vasculogenic mimicry activity for human gallbladder cancers through downregulating MMP-2 and MT1-MMP von ZHU, WEI, SUN, WEI, ZHANG, JING-TAO, LIU, ZHONG-YAN, LI, XIN-PING, FAN, YUE-ZU

“… Vasculogenic mimicry (VM) is a tumor microcirculation pattern in highly aggressive gallbladder cancers (GBCs). We recently reported the anti-VM activity of …”
Volltext

Enhanced levels of prostaglandin E2 and matrix metalloproteinase-2 correlate with the severity of airflow limitation in stable COPD von CHEN, Yan, CHEN, Ping, HANAOKA, Masayuki, DROMA, Yunden, KUBO, Keishi

“… ‐2, in the pathogenesis of COPD. Methods:  Forty‐three patients with stable COPD, twelve smoking control subjects and ten non …”
Volltext

Passive leg movement enhances interstitial VEGF protein, endothelial cell proliferation, and eNOS mRNA content in human skeletal muscle von Hellsten, Ylva, Rufener, Nora, Nielsen, Jens J, Høier, Birgitte, Krustrup, Peter, Bangsbo, Jens

“… The present study used passive limb movement as an experimental model to study the effect of increased blood flow and passive stretch, without enhanced metabolic demand, in young healthy male subjects …”
Weitere Angaben

EMMPRIN/CD147-encriched membrane vesicles released from malignant human testicular germ cells increase MMP production through tumor–stroma interaction von Milia-Argeiti, Eleni, Mourah, Samia, Vallée, Benoit, Huet, Eric, Karamanos, Nikos K., Theocharis, Achilleas D., Menashi, Suzanne

“… Elevated levels of EMMPRIN/CD147 in cancer tissues have been correlated with tumor progression but the regulation of its expression is not yet understood …”
Volltext

Doxycycline inhibits matrix metalloproteinase‐2 secretion from TSC2‐null mouse embryonic fibroblasts and lymphangioleiomyomatosis cells von Moir, LM, Ng, HY, Poniris, MH, Santa, T, Burgess, JK, Oliver, BGG, Krymskaya, VP, Black, JL

“… ) were cultured in DMEM containing 10% fetal bovine serum (FBS). Human LAM cells were derived from the lungs of LAM patients and airway smooth muscle cells from control subjects …”
Volltext

A role for matrix remodelling proteins in invasive and malignant meningiomas von Jalali, Shahrzad, Singh, Sanjay, Agnihotri, Sameer, Wataya, Takafumi, Salehi, Fatemeh, Alkins, R., Burrell, Kelly, Navab, Roya, Croul, Sidney, Aldape, Kenneth, Zadeh, Gelareh

“… ‐time PCR or Western blot analyses. Malignant meningioma cell lines (F5) were subject to MMP16 …”
Volltext

IL-13 and TH2 cytokine exposure triggers matrix metalloproteinase 7–mediated Fas ligand cleavage from bronchial epithelial cells von Wadsworth, Samuel J., Atsuta, Ryo, McIntyre, J. Oliver, Hackett, Tillie-Louise, Singhera, Gurpreet K., Dorscheid, Delbert R.

“… Airway tissue from healthy subjects and patients with severe asthma was used to investigate MMP expression patterns in diseased …”
Volltext

Aging alters gene expression of growth and remodeling factors in human skeletal muscle both at rest and in response to acute resistance exercise von Dennis, Richard A, Przybyla, Beata, Gurley, Cathy, Kortebein, Patrick M, Simpson, Pippa, Sullivan, Dennis H, Peterson, Charlotte A

“… and growth in skeletal muscle of young (32 +/- 7 yr, n = 15) and elderly (72 +/- 5 yr, n = 16) healthy subjects before and after a bout of resistance leg exercises …”
Weitere Angaben

Cells susceptible to epithelial-mesenchymal transition are enriched in stem-like side population cells from prostate cancer von LUO, YONG, CUI, XINHAO, ZHAO, JIAHUI, HAN, YILI, LI, MINGCHUAN, LIN, YUNHUA, JIANG, YONGGUANG, LAN, LING

“… Strategies for suppressing EMT remain the subject of ongoing research. In the present study, fluorescence-activated cell sorting (FACS …”
Volltext

Cutaneous MMPs are differently modulated by environmental stressors in old and young mice von Fortino, Vittoria, Maioli, Emanuela, Torricelli, Claudia, Davis, Paul, Valacchi, Giuseppe

“… ) or to CS for 4 days. Gelatin zymography revealed an increase of MMP-2 in both young and old animals, after exposure to pollutants, while MMP-9, undetectable in unexposed subjects, was strongly …”
Volltext

Expression of cyclooxygenase-2 and matrix metalloproteinase-2 in adenomyosis and endometrial polyps and its correlation with angiogenesis von Tokyol, Cigdem, Aktepe, Fatma, Dilek, Fatma Hüsniye, Sahin, Onder, Arioz, Dagstan Tolga

“… The subjects were 25 patients with adenomyosis, 30 patients with endometrial polyps, and 20 female controls …”
Weitere Angaben

Preexisting High Expression of Matrix Metalloproteinase-2 in Tunica Media of Saphenous Vein Conduits Is Associated with Unfavorable Long-Term Outcomes after Coronary Artery Bypass Grafting von Nowicki, Michał, Zabel, Maciej, Ostalska-Nowicka, Danuta, Misterski, Marcin, Malinska, Agnieszka, Perek, Bartlomiej, Perek, Anna

“… Migration of the smooth muscle cells (SMCs) to the tunica media in the saphenous vein (SV) transplants is facilitated by matrix metalloproteinases (MMPs). The …”
Volltext

Dysregulated atrial gene expression of osteoprotegerin/receptor activator of nuclear factor-κB (RANK)/RANK ligand axis in the development and progression of atrial fibrillation von Cao, Hailong, Wang, Jian, Xi, Lei, Røe, Oluf Dimitri, Chen, Yijiang, Wang, Dongjin

“… Clinical data, and biopsies of right atrial appendage were collected from sex- and age-matched subjects …”
Weitere Angaben

Gelatinases (MMP-2 and MMP-9) are preferentially expressed by Th1 vs. Th2 cells von Abraham, Michal, Shapiro, Sarah, Karni, Arnon, Weiner, Howard L., Miller, Ariel

“… In addition, Th1 in comparison to Th2 cells, from both human (healthy subjects and multiple sclerosis (MS) patients …”
Volltext

Elevated matrix metalloproteinase-2 and -3 production from human diabetic dermal fibroblasts von Wall, S.J., Sampson, M.J., Levell, N., Murphy, G.

“… Patients and methods Circular skin biopsies (4 mm diameter) were taken from the inside upper arm of four controls without diabetes and from four subjects with insulin‐treated diabetes …”
Volltext