Výsledky vyhľadávania - "Mammalian cells"

Stochastic mRNA Synthesis in Mammalian Cells Autor Raj, Arjun, Peskin, Charles S, Tranchina, Daniel, Vargas, Diana Y, Tyagi, Sanjay

“… We investigated the origins of these variations in mammalian cells by counting individual molecules of mRNA produced from a reporter gene that was stably integrated into the cell's genome…”
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Mitochondrial transcription in mammalian cells Autor Shokolenko, Inna N, Alexeyev, Mikhail F

“…As a consequence of recent discoveries of intimate involvement of mitochondria with key cellular processes, there has been a resurgence of interest in all…”
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How Mammalian Cells Acquire Copper: An Essential but Potentially Toxic Metal Autor Kaplan, Jack H, Maryon, Edward B

“… The initial step in cellular Cu handling is its transport across the plasma membrane, a subject of study for only about the last 25 years…”
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Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack Autor Wolfmeier, Heidi, Radecke, Julika, Schoenauer, Roman, Koeffel, René, Babiychuk, Viktoria S., Drücker, Patrick, Hathaway, Lucy J., Mitchell, Timothy J., Zuber, Benoît, Draeger, Annette, Babiychuk, Eduard B.

“…Streptococcus pneumoniae is a potent human pathogen. Its pore-forming exotoxin pneumolysin is instrumental for breaching the host's epithelial barrier and for…”
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Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells Autor Holland, Andrew J, Fachinetti, Daniele, Han, Joo Seok, Cleveland, Don W

“…Inducible degradation is a powerful approach for identifying the function of a specific protein or protein complex. Recently, a plant auxin-inducible degron…”
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Genetically Encoded Molecular Tension Probe for Tracing Protein-Protein Interactions in Mammalian Cells Autor Kim, Sung Bae, Nishihara, Ryo, Citterio, Daniel, Suzuki, Koji

“… We demonstrate an optical measure for visualizing molecular tension triggered by any PPI in mammalian cells…”
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Transient anomalous diffusion of telomeres in the nucleus of mammalian cells Autor Bronstein, I, Israel, Y, Kepten, E, Mai, S, Shav-Tal, Y, Barkai, E, Garini, Y

“… The short times diffusion may be explained by the reptation model and the transient diffusion is consistent with a model of telomeres that are subject to a local binding mechanism with a wide…”
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AFM imaging of the transcriptionally active chromatin in mammalian cells' nuclei Autor Bairamukov, V.Yu, Filatov, M.V., Kovalev, R.A., Fedorova, N.D., Pantina, R.A., Ankudinov, A.V., Iashina, E.G., Grigoriev, S.V., Varfolomeeva, E.Yu

“…Nuclear rigidity is traditionally associated with lamina and densely packed heterochromatin. Actively transcribed DNA is thought to be less densely packed…”
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Plasma membrane folding enables constant surface area-to-volume ratio in growing mammalian cells Autor Wu, Weida, Lam, Alice R, Suarez, Kayla, Smith, Grace N, Duquette, Sarah M, Yu, Jiaquan, Mankus, David, Bisher, Margaret, Lytton-Jean, Abigail, Manalis, Scott R, Miettinen, Teemu P

“… Here, we investigate near-spherical mammalian cells using single-cell measurements of cell mass and plasma membrane proteins and lipids, which allow us to examine the cell size scaling of cell…”
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Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells Autor Baccarini, Alessia, Chauhan, Hemangini, Gardner, Thomas J, Jayaprakash, Anitha D, Sachidanandam, Ravi, Brown, Brian D

“… To gain insight into this process, we carried out kinetic analysis of a miRNA's turnover following termination of its biogenesis and during regulation of a target that is not subject to Ago2-mediated catalytic cleavage…”
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Regulation of peptide‐chain elongation in mammalian cells Autor Browne, Gareth J., Proud, Christopher G.

“… Several of these proteins are subject to phosphorylation in mammalian cells, including the factors eEF1A and eEF1B that are involved in recruitment of amino acyl…”
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Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells Autor Schröder, Sebastian, Herker, Eva, Itzen, Friederike, He, Daniel, Thomas, Sean, Gilchrist, Daniel A, Kaehlcke, Katrin, Cho, Sungyoo, Pollard, Katherine S, Capra, John A, Schnölzer, Martina, Cole, Philip A, Geyer, Matthias, Bruneau, Benoit G, Adelman, Karen, Ott, Melanie

“… Here we report that the central regulator of transcription, RNA polymerase II, is subject to acetylation in mammalian cells…”
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Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells Autor Tian, Ya-Min, Holdship, Philip, To, Trang Quynh, Ratcliffe, Peter J., Keeley, Thomas P.

“…In animals, adaptation to changes in cellular oxygen levels is coordinated largely by 2-oxoglutarate-dependent prolyl-hydroxylase domain (PHD) dioxygenase…”
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Multiple assay systems to analyze the dynamics of mitochondrial nucleoids in living mammalian cells Autor Ishihara, Takaya, Kanon, Hirotaka, Ban-Ishihara, Reiko, Ishihara, Naotada

“…Mitochondria, which play a critical role in energy production by oxidative respiration, are highly dynamic organelles and their double membranes undergo…”
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Chromosome-wide co-fluctuation of stochastic gene expression in mammalian cells Autor Sun, Mengyi, Zhang, Jianzhi

“…Gene expression is subject to stochastic noise, but to what extent and by which means such stochastic variations are coordinated among different genes are unclear…”
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DNA Repair in Mammalian Cells Autor Tornaletti, S

“… This repair pathway was discovered in Phil Hanawalt's laboratory 20 years ago, but the mechanistic details are still subject of intense research…”
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DNA interstrand crosslink repair in mammalian cells: step by step Autor Muniandy, Parameswary A, Liu, Jia, Majumdar, Alokes, Liu, Su-ting, Seidman, Michael M.

“…). Despite considerable effort, our understanding of each step in mammalian cells is still quite limited…”
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FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells Autor Simandlova, Jitka, Zagelbaum, Jennifer, Payne, Miranda J, Chu, Wai Kit, Shevelev, Igor, Hanada, Katsuhiro, Chatterjee, Sujoy, Reid, Dylan A, Liu, Ying, Janscak, Pavel, Rothenberg, Eli, Hickson, Ian D

“… Because of its pivotal role in HR, RAD51 is subject to numerous positive and negative regulatory influences…”
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Intronic RNAs constitute the major fraction of the non-coding RNA in mammalian cells Autor St Laurent, Georges, Shtokalo, Dmitry, Tackett, Michael R, Yang, Zhaoqing, Eremina, Tatyana, Wahlestedt, Claes, Urcuqui-Inchima, Silvio, Seilheimer, Bernd, McCaffrey, Timothy A, Kapranov, Philipp

“…Background The function of RNA from the non-coding (the so called “dark matter”) regions of the genome has been a subject of considerable recent debate…”
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Selective cytotoxicity of intense nanosecond-duration electric pulses in mammalian cells Autor Ibey, Bennett L., Pakhomov, Andrei G., Gregory, Betsy W., Khorokhorina, Vera A., Roth, Caleb C., Rassokhin, Mikhail A., Bernhard, Joshua A., Wilmink, Gerald J., Pakhomova, Olga N.

“…Nanosecond electric pulses (EP) disrupt cell membrane and organelles and cause cell death in a manner different from the conventional irreversible…”
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