Suchergebnisse - "Magee, David A."

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle von Park, Stephen D E, Magee, David A., McGettigan, Paul A., Teasdale, Matthew D., Edwards, Ceiridwen J., Lohan, Amanda J., Murphy, Alison, Braud, Martin, Donoghue, Mark T., Liu, Yuan, Chamberlain, Andrew T., Rue-Albrecht, Kévin, Schroeder, Steven, Spillane, Charles, Tai, Shuaishuai, Bradley, Daniel G., Sonstegard, Tad S., Loftus, Brendan J., MacHugh, David E.

“… Background Domestication of the now-extinct wild aurochs, Bos primigenius , gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus  …”
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Diagnosis, treatment and management of lipodystrophy: the physician perspective on the patient journey von Patni, Nivedita, Chard, Craig, Araújo-Vilar, David, Phillips, Helen, Magee, David A., Akinci, Baris

“… Background Lipodystrophy syndromes are a heterogeneous group of rare, life-limiting diseases characterized by a selective loss of adipose tissue and severe …”
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A real-world pharmacovigilance assessment and literature review of lymphoma development in lipodystrophy von Brown, Rebecca J., Araujo-Vilar, David, Walkovich, Kelly J., Barbarosie, Alexandru, Magee, David A., Akinci, Baris, Oral, Elif A.

“… Metreleptin is a form of leptin replacement therapy used with diet and lifestyle modifications to treat the metabolic complications of leptin deficiency in …”
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Intragenic sequences in the trophectoderm harbour the greatest proportion of methylation errors in day 17 bovine conceptuses generated using assisted reproductive technologies von O’Doherty, Alan M., McGettigan, Paul, Irwin, Rachelle E., Magee, David A., Gagne, Dominic, Fournier, Eric, Al-Naib, Abdullah, Sirard, Marc-André, Walsh, Colum P., Robert, Claude, Fair, Trudee

“… Background Assisted reproductive technologies (ART) are widely used to treat fertility issues in humans and for the production of embryos in mammalian …”
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MicroRNA profiling of the bovine alveolar macrophage response to Mycobacterium bovis infection suggests pathogen survival is enhanced by microRNA regulation of endocytosis and lysosome trafficking von Vegh, Peter, Magee, David A., Nalpas, Nicolas C., Bryan, Kenneth, McCabe, Matthew S., Browne, John A., Conlon, Kevin M., Gordon, Stephen V., Bradley, Daniel G., MacHugh, David E., Lynn, David J.

“… Mycobacterium bovis, the causative agent of bovine tuberculosis, a major problem for global agriculture, spreads via an airborne route and is taken up by …”
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RNA Sequencing (RNA-Seq) Reveals Extremely Low Levels of Reticulocyte-Derived Globin Gene Transcripts in Peripheral Blood From Horses (Equus caballus) and Cattle (Bos taurus) von Correia, Carolina N., McLoughlin, Kirsten E., Nalpas, Nicolas C., Magee, David A., Browne, John A., Rue-Albrecht, Kevin, Gordon, Stephen V., MacHugh, David E.

“… RNA-seq has emerged as an important technology for measuring gene expression in peripheral blood samples collected from humans and other vertebrate species. In …”
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Genomic Characterisation of the Indigenous Irish Kerry Cattle Breed von Browett, Sam, McHugo, Gillian, Richardson, Ian W., Magee, David A., Park, Stephen D. E., Fahey, Alan G., Kearney, John F., Correia, Carolina N., Randhawa, Imtiaz A. S., MacHugh, David E.

“… Kerry cattle are an endangered landrace heritage breed of cultural importance to Ireland. In the present study we have used genome-wide SNP array data to …”
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RNA-seq Transcriptional Profiling of Peripheral Blood Leukocytes from Cattle Infected with Mycobacterium bovis von McLoughlin, Kirsten E., Nalpas, Nicolas C., Rue-Albrecht, Kévin, Browne, John A., Magee, David A., Killick, Kate E., Park, Stephen D. E., Hokamp, Karsten, Meade, Kieran G., O’Farrelly, Cliona, Gormley, Eamonn, Gordon, Stephen V., MacHugh, David E.

“… Bovine tuberculosis, caused by infection with Mycobacterium bovis, is a major endemic disease affecting cattle populations worldwide, despite the …”
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Pan-genomic analysis of bovine monocyte-derived macrophage gene expression in response to in vitro infection with Mycobacterium avium subspecies paratuberculosis von MacHugh, David E, Taraktsoglou, Maria, Killick, Kate E, Nalpas, Nicolas C, Browne, John A, DE Park, Stephen, Hokamp, Karsten, Gormley, Eamonn, Magee, David A

“… Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne’s disease, an intestinal disease of ruminants with major economic consequences …”
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Analysis of the Bovine Monocyte-Derived Macrophage Response to Mycobacterium avium Subspecies Paratuberculosis Infection Using RNA-seq von Casey, Maura E., Meade, Kieran G., Nalpas, Nicolas C., Taraktsoglou, Maria, Browne, John A., Killick, Kate E., Park, Stephen D. E., Gormley, Eamonn, Hokamp, Karsten, Magee, David A., MacHugh, David E.

“… Johne's disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious …”
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A Population Genomics Analysis of the Native Irish Galway Sheep Breed von McHugo, Gillian P., Browett, Sam, Randhawa, Imtiaz A. S., Howard, Dawn J., Mullen, Michael P., Richardson, Ian W., Park, Stephen D. E., Magee, David A., Scraggs, Erik, Dover, Michael J., Correia, Carolina N., Hanrahan, James P., MacHugh, David E.

“… The Galway sheep population is the only native Irish sheep breed and this livestock genetic resource is currently categorised as 'at-risk'. In the present …”
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A Complete Mitochondrial Genome Sequence from a Mesolithic Wild Aurochs (Bos primigenius) von Edwards, Ceiridwen J., Magee, David A., Park, Stephen D. E., McGettigan, Paul A., Lohan, Amanda J., Murphy, Alison, Finlay, Emma K., Shapiro, Beth, Chamberlain, Andrew T., Richards, Martin B., Bradley, Daniel G., Loftus, Brendan J., MacHugh, David E.

“… The derivation of domestic cattle from the extinct wild aurochs (Bos primigenius) has been well-documented by archaeological and genetic studies. Genetic …”
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Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis von Magee, David A., Taraktsoglou, Maria, Killick, Kate E., Nalpas, Nicolas C., Browne, John A., Park, Stephen D. E., Conlon, Kevin M., Lynn, David J., Hokamp, Karsten, Gordon, Stephen V., Gormley, Eamonn, MacHugh, David E.

“… Mycobacterium bovis, the causative agent of bovine tuberculosis, is a major cause of mortality in global cattle populations. Macrophages are among the first …”
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RNA-Seq Transcriptome Analysis of Peripheral Blood From Cattle Infected With Mycobacterium bovis Across an Experimental Time Course von McLoughlin, Kirsten E., Correia, Carolina N., Browne, John A., Magee, David A., Nalpas, Nicolas C., Rue-Albrecht, Kevin, Whelan, Adam O., Villarreal-Ramos, Bernardo, Vordermeier, H. Martin, Gormley, Eamonn, Gordon, Stephen V., MacHugh, David E.

“… Bovine tuberculosis, caused by infection with members of the Mycobacterium tuberculosis complex, particularly Mycobacterium bovis , is a major endemic disease …”
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Meta-Analysis of Mitochondrial DNA Reveals Several Population Bottlenecks during Worldwide Migrations of Cattle von Lenstra, Johannes, Ajmone-Marsan, Paolo, Beja-Pereira, Albano, Bollongino, Ruth, Bradley, Daniel, Colli, Licia, De Gaetano, Anna, Edwards, Ceiridwen, Felius, Marleen, Ferretti, Luca, Ginja, Catarina, Hristov, Peter, Kantanen, Juha, Lirón, Juan, Magee, David, Negrini, Riccardo, Radoslavov, Georgi

“… Several studies have investigated the differentiation of mitochondrial DNA in Eurasian, African and American cattle as well as archaeological bovine material …”
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Comparative Functional Genomics and the Bovine Macrophage Response to Strains of the Mycobacterium Genus von Rue-Albrecht, Kévin, Magee, David A., Killick, Kate E., Nalpas, Nicolas C., Gordon, Stephen V., MacHugh, David E.

“… Mycobacterial infections are major causes of morbidity and mortality in cattle and are also potential zoonotic agents with implications for human health …”
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Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes von Killick, Kate E, Browne, John A, Park, Stephen DE, Magee, David A, Martin, Irene, Meade, Kieran G, Gordon, Stephen V, Gormley, Eamonn, O'Farrelly, Cliona, Hokamp, Karsten, MacHugh, David E

“… Background Mycobacterium bovis is the causative agent of bovine tuberculosis (BTB), a pathological infection with significant economic impact. Recent studies …”
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Single Nucleotide Polymorphisms in the Insulin-Like Growth Factor 1 (IGF-1) Gene are Associated with Performance in Holstein-Friesian Dairy Cattle von Mullen, Michael Paul, Berry, Donagh P., Howard, Dawn J., Diskin, Michael G., Lynch, Ciaran O., Giblin, Linda, Kenny, David A., Magee, David A., Meade, Kieran G., Waters, Sinead M.

“… Insulin-like growth factor 1 (IGF-1) has been shown to be associated with fertility, growth, and development in cattle. The aim of this study was to (1) …”
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Key Hub and Bottleneck Genes Differentiate the Macrophage Response to Virulent and Attenuated Mycobacterium bovis von Killick, Kate E., Magee, David A., Park, Stephen D. E., Taraktsoglou, Maria, Browne, John A., Conlon, Kevin M., Nalpas, Nicolas C., Gormley, Eamonn, Gordon, Stephen V., MacHugh, David E., Hokamp, Karsten

“… Mycobacterium bovis is an intracellular pathogen that causes tuberculosis in cattle. Following infection, the pathogen resides and persists inside host …”
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Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples von Mullen, Michael P, Creevey, Christopher J, Berry, Donagh P, McCabe, Matt S, Magee, David A, Howard, Dawn J, Killeen, Aideen P, Park, Stephen D, McGettigan, Paul A, Lucy, Matt C, MacHugh, David E, Waters, Sinead M

“… Background The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification …”
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