Search Results - "Lopez de Jesus, Maider"
-
1
Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age
ISSN: 1422-0067, 1422-0067Published: Switzerland MDPI 09.02.2021Published in International journal of molecular sciences (09.02.2021)“…Platelet-rich plasma (PRP) is a biologic therapy that promotes healing responses across multiple medical fields, including the central nervous system (CNS)…”
Get full text
Journal Article -
2
Isolation of Platelet-Derived Exosomes from Human Platelet-Rich Plasma: Biochemical and Morphological Characterization
ISSN: 1422-0067, 1661-6596, 1422-0067Published: Switzerland MDPI AG 05.03.2022Published in International journal of molecular sciences (05.03.2022)“…Platelet-Rich Plasma (PRP) is enriched in molecular messengers with restorative effects on altered tissue environments. Upon activation, platelets release a…”
Get full text
Journal Article -
3
Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation
ISSN: 0021-9258Published: United States 04.08.2006Published in The Journal of biological chemistry (04.08.2006)“…The activation of the Ras-related GTPase R-Ras, which has been implicated in the regulation of various cellular functions, by G protein-coupled receptors…”
Get more information
Journal Article -
4
Endocannabinoid 2-Arachidonoylglycerol Synthesis and Metabolism at Neuronal Nuclear Matrix Fractions Derived from Adult Rat Brain Cortex
ISSN: 1422-0067, 1661-6596, 1422-0067Published: Switzerland MDPI AG 05.02.2023Published in International journal of molecular sciences (05.02.2023)“…In this report, we describe the kinetics characteristics of the diacylglycerol lipase-α (DGLα) located at the nuclear matrix of nuclei derived from adult…”
Get full text
Journal Article -
5
Fit-for-purpose based testing and validation of antibodies to amino- and carboxy-terminal domains of cannabinoid receptor 1
ISSN: 0948-6143, 1432-119X, 1432-119XPublished: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2021Published in Histochemistry and cell biology (01.11.2021)“…Specific and selective anti-CB 1 antibodies are among the most powerful research tools to unravel the complex biological processes mediated by the CB 1…”
Get full text
Journal Article -
6
Design and validation of recombinant protein standards for quantitative Western blot analysis of cannabinoid CB1 receptor density in cell membranes: an alternative to radioligand binding methods
ISSN: 1475-2859, 1475-2859Published: London BioMed Central 15.09.2022Published in Microbial cell factories (15.09.2022)“…Background Replacement of radioligand binding assays with antibody-antigen interaction-based approaches for quantitative analysis of G protein-coupled receptor…”
Get full text
Journal Article -
7
PLCβ1 by-passes early growth response -1 to induce the differentiation of neuronal cells
ISSN: 2058-7716, 2058-7716Published: London Nature Publishing Group UK 24.05.2024Published in Cell death discovery (24.05.2024)“…The Gα q /phospholipase C-β (PLCβ) signaling system mediates calcium responses to a variety of hormones and neurotransmitters. Recent studies suggest that…”
Get full text
Journal Article -
8
Up-regulation of CB1 cannabinoid receptors located at glutamatergic terminals in the medial prefrontal cortex of the obese Zucker rat
ISSN: 1662-5129, 1662-5129Published: Lausanne Frontiers Research Foundation 18.10.2022Published in Frontiers in neuroanatomy (18.10.2022)“…The present study describes a detailed neuroanatomical distribution map of the cannabinoid type 1 (CB 1 ) receptor, along with the biochemical characterization…”
Get full text
Journal Article -
9
New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
ISSN: 1543-8392Published: United States 02.11.2015Published in Molecular pharmaceutics (02.11.2015)“…The transfection of human NTera2/D1 teratocarcinoma-derived cell line (or NT2 cells) represents a promising strategy for the delivery of exogenous proteins or…”
Get more information
Journal Article -
10
Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin
ISSN: 0261-4189, 1460-2075Published: Chichester, UK John Wiley & Sons, Ltd 03.10.2007Published in The EMBO journal (03.10.2007)“…The activity state of cofilin, which controls actin dynamics, is driven by a phosphorylation–dephosphorylation cycle. Phosphorylation of cofilin by LIM‐kinases…”
Get full text
Journal Article -
11
Levels of G-protein αq/11 subunits and of phospholipase C-β(1–4), -γ, and -δ1 isoforms in postmortem human brain caudate and cortical membranes: Potential functional implications
ISSN: 0197-0186Published: Oxford Elsevier 01.07.2006Published in Neurochemistry international (01.07.2006)Get full text
Journal Article -
12
Highly efficient generation of glutamatergic/cholinergic NT2-derived postmitotic human neurons by short-term treatment with the nucleoside analogue cytosine β-d-arabinofuranoside
ISSN: 1873-5061, 1876-7753, 1876-7753Published: England Elsevier B.V 01.03.2016Published in Stem cell research (01.03.2016)“…The human NTERA2/D1 (NT2) cells generate postmitotic neurons (NT2N cells) upon retinoic acid (RA) treatment and are functionally integrated in the host tissue…”
Get full text
Journal Article -
13
B cell receptor-induced growth arrest and apoptosis in WEHI-231 immature B lymphoma cells involve cyclic AMP and Epac proteins
ISSN: 0898-6568, 1873-3913, 1873-3913Published: England Elsevier Inc 01.04.2009Published in Cellular signalling (01.04.2009)“…Signaling by the B cell antigen receptor (BCR) is essential for B lymphocyte homeostasis and immune function. In immature B cells, ligation of the BCR promotes…”
Get full text
Journal Article -
14
siRNA Bidezko Gene-Isilpena: Mekanismoak, Estrategiak eta Aplikazio Klinikoak
ISSN: 0214-9001, 2444-3255Published: 29.09.2025Published in EKAIA Euskal Herriko Unibertsitateko Zientzia eta Teknologia Aldizkaria (29.09.2025)“…Interferentziazko RNA, sarritan RNAi gisa laburtuta, eukarioto ugaritan aurkitzen den kate bikoitzeko RNA (dsRNA) molekula hartuta, transkripziozko geneak…”
Get full text
Journal Article -
15
Nuclear diacylglycerol lipase-[alpha] in rat brain cortical neurons: evidence of 2-arachidonoylglycerol production in concert with phospholipase C-[beta] activity
ISSN: 0022-3042, 1471-4159Published: New York Blackwell Publishing Ltd 01.03.2015Published in Journal of neurochemistry (01.03.2015)“…In this report, we describe the localization of diacylglycerol lipase-[alpha] (DAGL[alpha]) in nuclei from adult cortical neurons, as assessed by…”
Get full text
Journal Article -
16
Data for the morphometric characterization of NT2-derived postmitotic neurons
ISSN: 2352-3409, 2352-3409Published: Netherlands Elsevier Inc 01.06.2016Published in Data in brief (01.06.2016)“…NTERA2/D1 human teratocarcinoma progenitors induced to differentiate into postmitotic neurons by either long-term treatment with retinoic acid or short-term…”
Get full text
Journal Article -
17
Effects of intramuscular administration of Platelet-Rich Plasma on denervated muscle after peripheral nerve injury
ISSN: 0300-8207, 1607-8438, 1607-8438Published: England 02.01.2025Published in Connective tissue research (02.01.2025)“…After peripheral nerve injury (PNI), prolonged denervation of the target muscle prevents adequate reinnervation even if the nerve is repaired. The aim of this…”
Get full text
Journal Article -
18
Nuclear diacylglycerol lipase‐α in rat brain cortical neurons: evidence of 2‐arachidonoylglycerol production in concert with phospholipase C‐β activity
ISSN: 0022-3042, 1471-4159, 1471-4159Published: England 01.03.2015Published in Journal of neurochemistry (01.03.2015)“…In this report, we describe the localization of diacylglycerol lipase‐α (DAGLα) in nuclei from adult cortical neurons, as assessed by double‐immunofluorescence…”
Get full text
Journal Article -
19
Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas
ISSN: 0197-0186, 1872-9754, 1872-9754Published: Kidlington Elsevier 01.05.2010Published in Neurochemistry international (01.05.2010)“…Gliomas are the most important group of malignant primary brain tumors and one of the most aggressive forms of cancer. During the last years, several studies…”
Get full text
Journal Article -
20
Phospholipase D signaling: orchestration by PIP2 and small GTPases
ISSN: 0028-1298, 1432-1912Published: Germany Springer-Verlag 01.02.2007Published in Naunyn-Schmiedeberg's archives of pharmacology (01.02.2007)“…Hydrolysis of phosphatidylcholine by phospholipase D (PLD) leads to the generation of the versatile lipid second messenger, phosphatidic acid (PA), which is…”
Get full text
Journal Article