Suchergebnisse - "Legido Quigley, C."

Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease von Proitsi, P, Kim, M, Whiley, L, Pritchard, M, Leung, R, Soininen, H, Kloszewska, I, Mecocci, P, Tsolaki, M, Vellas, B, Sham, P, Lovestone, S, Powell, J F, Dobson, R J B, Legido-Quigley, C

“… There is an urgent need for the identification of Alzheimer’s disease (AD) biomarkers. Studies have now suggested the promising use of associations with blood …”
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Study of short polystyrene monolith-fritted micro-liquid chromatography columns for analysis of neutral and basic compounds von Legido-Quigley, C, Smith, N.W

“… This study details the effects of poly(styrene-divinylbenzene) (PS-DVB) frits in micro-HPLC columns for the separation of neutral and basic compounds. The …”
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The new neurobiology of dementia von Thambisetty, M., Varma, V., An, Y., Mahajan, U., Oommen, A., Varma, S., Troncoso, J., Pletnikova, O., Legido-Quigley, C.

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P6 LIPIDOME INVESTIGATION OF DBD, DCD AND LRD LIVERS SHOWS DIFFERENCES IN LIPID MEDIATED INTRACELLULAR SIGNALLING PATHWAYS von Sen, A., Shkodra, M., Tena, M., Xystrakis, E., Srinivasan, P., Vilca-Melendez, H., Heaton, N., Ma, Y., Jassem, W., Legido-Quigley, C.

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Neuroprotective effects of oxyresveratrol on 6-hydroxydopamine on medial forebrain bundles in a rat model of Parkinson disease: abridged secondary publication von Shah, A, Ho, Y S, Ng, K M, Wang, M, Legido-Quigley, C, Chang, R C C

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Metabolite-biomarker investigations in the life cycle of and infection with Schistosoma von Legido-Quigley, C.

“… Schistosome infection is endemic in many Third World countries and affects an estimated 200 million individuals. Over the last few years, a number of …”
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Metabolic fingerprinting with capillary electrophoresis von García-Pérez, I., Vallejo, M., García, A., Legido-Quigley, C., Barbas, C.

“… Increasingly biomedical studies require a top-down approach that can be achieved by comparing patterns, signatures or “fingerprints” of metabolites that change …”
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Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins von Voyle, N, Kim, M, Proitsi, P, Ashton, N J, Baird, A L, Bazenet, C, Hye, A, Westwood, S, Chung, R, Ward, M, Rabinovici, G D, Lovestone, S, Breen, G, Legido-Quigley, C, Dobson, R J B, Kiddle, S J

“… We believe this is the first study to investigate associations between blood metabolites and neocortical amyloid burden (NAB) in the search for a blood-based …”
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P0032 : The impact of Ischemia/Reperfusion injury on liver allografts from deceased after cardiac death versus deceased after brain death donors von Amir Sayed, B., Xu, J., Casas-Ferreira, A.M., Srinivasan, P., Heaton, N., Ma, Y., Legido-Quigley, C., Fuggle, S., Jassem, W.

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Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model von Garcia-Perez, I, Couto Alves, A, Angulo, S, Li, J V, Utzinger, J, Ebbels, T M D, Legido-Quigley, C, Nicholson, J K, Holmes, E, Barbas, C

“… We demonstrate the statistical integration of nuclear magnetic resonance (NMR) spectroscopy and capillary electrophoresis (CE) data in order to describe a …”
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Chromatographic characterisation, under highly aqueous conditions, of a molecularly imprinted polymer binding the herbicide 2,4-dichlorophenoxyacetic acid von Legido-Quigley, C., Oxelbark, J., De Lorenzi, E., Zurutuza-Elorza, A., Cormack, P.A.G.

“… The affinity of a 2,4-dichlorophenoxyacetic acid (2,4-D) molecularly imprinted polymer (MIP), which was synthesised directly in an aqueous organic solvent, for …”
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Quantification of the sensitivity increase of a micro-high-performance liquid chromatography–electrospray ionization mass spectrometry system with decreasing column diameter von Legido-Quigley, C, Smith, N.W, Mallet, D

“… This study details the sensitivity achieved with capillary columns when used with a micro-HPLC–electrospray ionization MS system. It is comprised of two …”
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Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum von Bos, Isabelle, Vos, Stephanie, Verhey, Frans, Scheltens, Philip, Teunissen, Charlotte, Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni, Blin, Olivier, Richardson, Jill C, Bordet, Régis, Tsolaki, Magda, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Lleó, Alberto, Johannsen, Peter, Freund-Levi, Yvonne, Frölich, Lutz, Vandenberghe, Rik, Westwood, Sarah, Dobricic, Valerija, Barkhof, Frederik, Legido-Quigley, Cristina, Bertram, Lars, Lovestone, Simon, Streffer, Johannes, Andreasson, Ulf, Blennow, Kaj, Zetterberg, Henrik, Visser, Pieter Jelle

“… We investigated relations between amyloid-β (Aβ) status, apolipoprotein E (APOE) ε4, and cognition, with cerebrospinal fluid markers of neurogranin (Ng), …”
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Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes von Hendriks, A. Emile J., Marcovecchio, M. Loredana, Besser, Rachel E. J., Bonifacio, Ezio, Casteels, Kristina, Elding Larsson, Helena, Gemulla, Gita, Lundgren, Markus, Kordonouri, Olga, Mallone, Roberto, Pociot, Flemming, Szypowska, Agnieszka, Toppari, Jorma, Ziegler, Anette G., Mathieu, Chantal, Achenbach, Peter, Mathieu, C., Gillard, P., Casteels, K., Overbergh, L., Wallace, C., Evans, M., Thankamony, A., Hendriks, A. E. J., Bruggraber, S., Marcovecchio, M. L., Peakman, M., Tree, T., Richardson, S., Todd, J., Wicker, L., Mander, A., Dayan, C., Alhadj Ali, M., Pieber, T., Eizirik, D., Cnop, M., Brunak, S., Pociot, F., Johannesen, J., Rossing, P., Legido Quigley, C., Mallone, R., Scharfmann, R., Boitard, C., Knip, M., Otonkoski, T., Lahesmaa, R., Oresic, M., Toppari, J., Danne, T., Ziegler, A. G., Achenbach, P., Rodriguez‐Calvo, T., Solimena, M., Bonifacio, E., Speier, S., Holl, R., Dotta, F., Chiarelli, F., Marchetti, P., Bosi, E., Cianfarani, S., Ciampalini, P., Beaufort, C., Dahl‐Jørgensen, K., Skrivarhaug, T., Krogvold, L., Jarosz‐Chobot, P., Battelino, T., Thorens, B., Roep, B., Nikolic, T., Zaldumbide, A., Lernmark, A., Costecalde, G., Strube, T., Schulte, A., Nitsche, A., Peakman, M., Vela, J., Herrath, M., Wesley, J., Napolitano‐Rosen, A., Thomas, M., Schloot, N., Goldfine, A., Waldron‐Lynch, F., Kompa, J., Vedala, A., Hartmann, N., Nicolas, G., Rampelbergh, J., Bovy, N., Dutta, S., Soderberg, J., Ahmed, S., Martin, F., Latres, E., Koralova, A.

“… Background/Aim Type 1 diabetes is an autoimmune disease that involves the development of autoantibodies against pancreatic islet beta‐cell antigens, preceding …”
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Urinary metabolic phenotyping for Alzheimer’s disease von Kurbatova, Natalja, Garg, Manik, Whiley, Luke, Chekmeneva, Elena, Jiménez, Beatriz, Gómez-Romero, María, Pearce, Jake, Kimhofer, Torben, D’Hondt, Ellie, Soininen, Hilkka, Kłoszewska, Iwona, Mecocci, Patrizia, Tsolaki, Magda, Vellas, Bruno, Aarsland, Dag, Nevado-Holgado, Alejo, Liu, Benjamine, Snowden, Stuart, Proitsi, Petroula, Ashton, Nicholas J., Hye, Abdul, Legido-Quigley, Cristina, Lewis, Matthew R., Nicholson, Jeremy K., Holmes, Elaine, Brazma, Alvis, Lovestone, Simon

“… Finding early disease markers using non-invasive and widely available methods is essential to develop a successful therapy for Alzheimer’s Disease. Few studies …”
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Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation von Neumann, Alexander, Küçükali, Fahri, Bos, Isabelle, Vos, Stephanie J B, Engelborghs, Sebastiaan, De Pooter, Tim, Joris, Geert, De Rijk, Peter, De Roeck, Ellen, Tsolaki, Magda, Verhey, Frans, Martinez-Lage, Pablo, Tainta, Mikel, Frisoni, Giovanni, Blin, Oliver, Richardson, Jill, Bordet, Régis, Scheltens, Philip, Popp, Julius, Peyratout, Gwendoline, Johannsen, Peter, Frölich, Lutz, Vandenberghe, Rik, Freund-Levi, Yvonne, Streffer, Johannes, Lovestone, Simon, Legido-Quigley, Cristina, Ten Kate, Mara, Barkhof, Frederik, Strazisar, Mojca, Zetterberg, Henrik, Bertram, Lars, Visser, Pieter Jelle, van Broeckhoven, Christine, Sleegers, Kristel

“… Alzheimer's disease (AD) biomarkers represent several neurodegenerative processes, such as synaptic dysfunction, neuronal inflammation and injury, as well as …”
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Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN‐derived networks and highlights causal links in Alzheimer's disease von Shi, Liu, Xu, Jin, Green, Rebecca, Wretlind, Asger, Homann, Jan, Buckley, Noel J., Tijms, Betty M., Vos, Stephanie J. B., Lill, Christina M., Kate, Mara ten, Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni B., Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez‐Lage, Pablo, Streffer, Johannes, Barkhof, Frederik, Zetterberg, Henrik, Visser, Pieter Jelle, Lovestone, Simon, Bertram, Lars, Nevado‐Holgado, Alejo J., Proitsi, Petroula, Legido‐Quigley, Cristina

“… Introduction This study employed an integrative system and causal inference approach to explore molecular signatures in blood and CSF, the …”
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The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics von Bos, Isabelle, Vos, Stephanie, Vandenberghe, Rik, Scheltens, Philip, Engelborghs, Sebastiaan, Frisoni, Giovanni, Molinuevo, José Luis, Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez-Lage, Pablo, Baird, Alison, Dobson, Richard, Legido-Quigley, Cristina, Sleegers, Kristel, Van Broeckhoven, Christine, Bertram, Lars, ten Kate, Mara, Barkhof, Frederik, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Visser, Pieter Jelle

“… Background There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer’s disease (AD) in the predementia stages and to predict the rate of …”
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MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study von ten Kate, Mara, Redolfi, Alberto, Peira, Enrico, Bos, Isabelle, Vos, Stephanie J., Vandenberghe, Rik, Gabel, Silvy, Schaeverbeke, Jolien, Scheltens, Philip, Blin, Olivier, Richardson, Jill C., Bordet, Regis, Wallin, Anders, Eckerstrom, Carl, Molinuevo, José Luis, Engelborghs, Sebastiaan, Van Broeckhoven, Christine, Martinez-Lage, Pablo, Popp, Julius, Tsolaki, Magdalini, Verhey, Frans R. J., Baird, Alison L., Legido-Quigley, Cristina, Bertram, Lars, Dobricic, Valerija, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Bianchetti, Silvia, Novak, Gerald P., Revillard, Jerome, Gordon, Mark F., Xie, Zhiyong, Wottschel, Viktor, Frisoni, Giovanni, Visser, Pieter Jelle, Barkhof, Frederik

“… Background With the shift of research focus towards the pre-dementia stage of Alzheimer’s disease (AD), there is an urgent need for reliable, non-invasive …”
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Exploration of Plasma Lipids in Mild Cognitive Impairment due to Alzheimer's Disease von Bergland, Anne Katrine, Proitsi, Petroula, Kirsebom, Bjørn-Eivind, Soennesyn, Hogne, Hye, Abdul, Larsen, Alf Inge, Xu, Jin, Legido-Quigley, Cristina, Rajendran, Lawrence, Fladby, Tormod, Aarsland, Dag

“… Lipids have important structural roles in cell membranes and changes to these membrane lipids may influence β- and γ-secretase activities and thus contribute …”
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