Výsledky vyhledávání - "Lavigne, Rob"

SAPPHIRE: a neural network based classifier for σ70 promoter prediction in Pseudomonas Autor Coppens, Lucas, Lavigne, Rob

“…Background In silico promoter prediction represents an important challenge in bioinformatics as it provides a first-line approach to identifying regulatory…”
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Pseudomonas predators: understanding and exploiting phage–host interactions Autor De Smet, Jeroen, Hendrix, Hanne, Blasdel, Bob G., Danis-Wlodarczyk, Katarzyna, Lavigne, Rob

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Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review Autor Uyttebroek, Saartje, Chen, Baixing, Onsea, Jolien, Ruythooren, Fred, Debaveye, Yves, Devolder, David, Spriet, Isabel, Depypere, Melissa, Wagemans, Jeroen, Lavigne, Rob, Pirnay, Jean-Paul, Merabishvili, Maya, De Munter, Paul, Peetermans, Willy E, Dupont, Lieven, Van Gerven, Laura, Metsemakers, Willem-Jan

“…According to the latest reports from WHO, the incidence of antibiotic-resistant bacterial infections is increasing worldwide, resulting in increased morbidity…”
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Taxonomic assignment of uncultivated prokaryotic virus genomes is enabled by gene-sharing networks Autor Bin Jang, Ho, Bolduc, Benjamin, Zablocki, Olivier, Kuhn, Jens H, Roux, Simon, Adriaenssens, Evelien M, Brister, J Rodney, Kropinski, Andrew M, Krupovic, Mart, Lavigne, Rob, Turner, Dann, Sullivan, Matthew B

“…Microbiomes from every environment contain a myriad of uncultivated archaeal and bacterial viruses, but studying these viruses is hampered by the lack of a…”
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Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections Autor Henry, Marine, Lavigne, Rob, Debarbieux, Laurent

“…The potential of bacteriophage therapy to treat infections caused by antibiotic-resistant bacteria has now been well established using various animal models…”
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Exploring the synthetic biology potential of bacteriophages for engineering non-model bacteria Autor Lammens, Eveline-Marie, Nikel, Pablo Ivan, Lavigne, Rob

“…Non-model bacteria like Pseudomonas putida , Lactococcus lactis and other species have unique and versatile metabolisms, offering unique opportunities for…”
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Targeting mechanisms of tailed bacteriophages Autor Nobrega, Franklin L, Vlot, Marnix, de Jonge, Patrick A, Dreesens, Lisa L, Beaumont, Hubertus J E, Lavigne, Rob, Dutilh, Bas E, Brouns, Stan J J

“…Phages differ substantially in the bacterial hosts that they infect. Their host range is determined by the specific structures that they use to target…”
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Pro- and anti-inflammatory responses of peripheral blood mononuclear cells induced by Staphylococcus aureus and Pseudomonas aeruginosa phages Autor Van Belleghem, Jonas D., Clement, Frédéric, Merabishvili, Maya, Lavigne, Rob, Vaneechoutte, Mario

“…The ability of bacteriophages to kill bacteria is well known, as is their potential use as alternatives to antibiotics. As such, bacteriophages reach high…”
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Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae Autor Eskenazi, Anaïs, Lood, Cédric, Wubbolts, Julia, Hites, Maya, Balarjishvili, Nana, Leshkasheli, Lika, Askilashvili, Lia, Kvachadze, Leila, van Noort, Vera, Wagemans, Jeroen, Jayankura, Marc, Chanishvili, Nina, de Boer, Mark, Nibbering, Peter, Kutateladze, Mzia, Lavigne, Rob, Merabishvili, Maya, Pirnay, Jean-Paul

“…A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella pneumoniae infection after long-term (>700 days) antibiotic therapy is…”
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Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler Autor Van Nieuwenhuyse, Brieuc, Van der Linden, Dimitri, Chatzis, Olga, Lood, Cédric, Wagemans, Jeroen, Lavigne, Rob, Schroven, Kaat, Paeshuyse, Jan, de Magnée, Catherine, Sokal, Etienne, Stéphenne, Xavier, Scheers, Isabelle, Rodriguez-Villalobos, Hector, Djebara, Sarah, Merabishvili, Maya, Soentjens, Patrick, Pirnay, Jean-Paul

“…Post-operative bacterial infections are a leading cause of mortality and morbidity after ongoing liver transplantation. Bacteria causing these infections in…”
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Two Phages, phiIPLA-RODI and phiIPLA-C1C, Lyse Mono- and Dual-Species Staphylococcal Biofilms Autor Gutiérrez, Diana, Vandenheuvel, Dieter, Martínez, Beatriz, Rodríguez, Ana, Lavigne, Rob, García, Pilar

“…Phage therapy is a promising option for fighting against staphylococcal infections. Two lytic phages, vB_SauM_phiIPLA-RODI (phiIPLA-RODI) and…”
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Evaluation of the genomic diversity of viruses infecting bacteria, archaea and eukaryotes using a common bioinformatic platform: steps towards a unified taxonomy Autor Aiewsakun, Pakorn, Adriaenssens, Evelien M, Lavigne, Rob, Kropinski, Andrew M, Simmonds, Peter

“…Genome Relationship Applied to Virus Taxonomy (GRAViTy) is a genetics-based tool that computes sequence relatedness between viruses. Composite generalized…”
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role of interactions between phage and bacterial proteins within the infected cell: a diverse and puzzling interactome Autor Roucourt, Bart, Lavigne, Rob

“…Interactions between bacteriophage proteins and bacterial proteins are important for efficient infection of the host cell. The phage proteins involved in these…”
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Targeting Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offs Autor Kunisch, Fabian, Campobasso, Claudia, Wagemans, Jeroen, Yildirim, Selma, Chan, Benjamin K., Schaudinn, Christoph, Lavigne, Rob, Turner, Paul E., Raschke, Michael J., Trampuz, Andrej, Gonzalez Moreno, Mercedes

“…Spread of multidrug-resistant Pseudomonas aeruginosa strains threatens to render currently available antibiotics obsolete, with limited prospects for the…”
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Deconstructing the Phage–Bacterial Biofilm Interaction as a Basis to Establish New Antibiofilm Strategies Autor Visnapuu, Annegrete, Van der Gucht, Marie, Wagemans, Jeroen, Lavigne, Rob

“…The bacterial biofilm constitutes a complex environment that endows the bacterial community within with an ability to cope with biotic and abiotic stresses…”
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Engineered Endolysin-Based “Artilysins” To Combat Multidrug-Resistant Gram-Negative Pathogens Autor Briers, Yves, Walmagh, Maarten, Van Puyenbroeck, Victor, Cornelissen, Anneleen, Cenens, William, Aertsen, Abram, Oliveira, Hugo, Azeredo, Joana, Verween, Gunther, Pirnay, Jean-Paul, Miller, Stefan, Volckaert, Guido, Lavigne, Rob

“…The global threat to public health posed by emerging multidrug-resistant bacteria in the past few years necessitates the development of novel approaches to…”
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Position paper: The creation of a rational scheme for the nomenclature of viruses of Bacteria and Archaea Autor Kropinski, Andrew M., Prangishvili, David, Lavigne, Rob

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Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii Autor Defraine, Valerie, Schuermans, Joris, Grymonprez, Barbara, Govers, Sander K, Aertsen, Abram, Fauvart, Maarten, Michiels, Jan, Lavigne, Rob, Briers, Yves

“…Bacteriophage-encoded endolysins have shown promise as a novel class of antibacterials with a unique mode of action, i.e., peptidoglycan degradation. However,…”
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Art-175 is a highly efficient antibacterial against multidrug-resistant strains and persisters of Pseudomonas aeruginosa Autor Briers, Yves, Walmagh, Maarten, Grymonprez, Barbara, Biebl, Manfred, Pirnay, Jean-Paul, Defraine, Valerie, Michiels, Jan, Cenens, William, Aertsen, Abram, Miller, Stefan, Lavigne, Rob

“…Artilysins constitute a novel class of efficient enzyme-based antibacterials. Specifically, they covalently combine a bacteriophage-encoded endolysin, which…”
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A Thermostable Salmonella Phage Endolysin, Lys68, with Broad Bactericidal Properties against Gram-Negative Pathogens in Presence of Weak Acids Autor Oliveira, Hugo, Thiagarajan, Viruthachalam, Walmagh, Maarten, Sillankorva, Sanna, Lavigne, Rob, Neves-Petersen, Maria Teresa, Kluskens, Leon D., Azeredo, Joana

“…Resistance rates are increasing among several problematic Gram-negative pathogens, a fact that has encouraged the development of new antimicrobial agents. This…”
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