Výsledky vyhľadávania - "Lau, Jillian S"

Impact of a TLR9 agonist and broadly neutralizing antibodies on HIV-1 persistence: the randomized phase 2a TITAN trial Autor Gunst, Jesper D., Højen, Jesper F., Pahus, Marie H., Rosás-Umbert, Miriam, Stiksrud, Birgitte, McMahon, James H., Denton, Paul W., Nielsen, Henrik, Johansen, Isik S., Benfield, Thomas, Leth, Steffen, Gerstoft, Jan, Østergaard, Lars, Schleimann, Mariane H., Olesen, Rikke, Støvring, Henrik, Vibholm, Line, Weis, Nina, Dyrhol-Riise, Anne M., Pedersen, Karen B. H., Lau, Jillian S. Y., Copertino, Dennis C., Linden, Noemi, Huynh, Tan T., Ramos, Victor, Jones, R. Brad, Lewin, Sharon R., Tolstrup, Martin, Rasmussen, Thomas A., Nussenzweig, Michel C., Caskey, Marina, Reikvam, Dag Henrik, Søgaard, Ole S.

“…Inducing antiretroviral therapy (ART)-free virological control is a critical step toward a human immunodeficiency virus type 1 (HIV-1) cure. In this phase 2a,…”
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Long-Term Outcomes Following Suppressive Antibiotic Therapy: A 10-Year Cohort Study Autor George, Ruth, Kiss, Christopher, Woolley, Ian, Lau, Jillian S. Y.

“…Background: Lifelong antibiotic therapy can be used as a strategy to manage chronic infections deemed incurable. While this may be beneficial in suppressing…”
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HIV and the gut: implications for HIV persistence, immune dysfunction and cure strategies Autor Lau, Jillian S. Y., Lewin, Sharon R., Telwatte, Sushama

“…The intestinal immune compartment plays a central role in HIV pathogenesis, serving as an early site for viral replication and a significant reservoir for…”
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Acceptability, motivation and the prospect of cure for people living with HIV and their healthcare providers in HIV cure-focused treatment interruption studies Autor Lau, Jillian S. Y., Smith, Miranda Z., Allan, Brent, Martinez, Cipriano, Power, Jennifer, Lewin, Sharon R., McMahon, James H.

“…Background Analytical treatment interruptions (ATI) are commonly used clinical endpoints to assess interventions aimed at curing HIV or achieving…”
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An adaptive randomised placebo controlled phase II trial of antivirals for COVID-19 infection (VIRCO): A structured summary of a study protocol for a randomised controlled trial Autor McMahon, James H., Lau, Jillian S. Y., Roney, Janine, Rogers, Benjamin A., Trubiano, Jason, Sasadeusz, Joseph, Molton, James S., Gardiner, Bradley, Lee, Sue J., Hoy, Jennifer F., Cheng, Allen, Peleg, Anton Y.

“…Objectives Primary objective: To determine the efficacy of a candidate antiviral on time to virological cure compared to standard of care within 14 days of…”
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The Use of Long-term Antibiotics for Suppression of Bacterial Infections Autor Horne, Molly, Woolley, Ian, Lau, Jillian S Y

“…Suppressive antibiotic therapy is prescribed when a patient has an infection that is presumed to be incurable by a defined course of therapy or source control…”
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Surveillance of life-long antibiotics: a review of antibiotic prescribing practices in an Australian Healthcare Network Autor Lau, Jillian S. Y., Kiss, Christopher, Roberts, Erika, Horne, Kylie, Korman, Tony M., Woolley, Ian

“…Background The rise of antimicrobial use in the twentieth century has significantly reduced morbidity due to infection, however it has also brought with it the…”
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Long-Term Outcomes in Patients on Life-Long Antibiotics: A Five-Year Cohort Study Autor Kiss, Christopher, Connoley, Declan, Connelly, Kathryn, Horne, Kylie, Korman, Tony, Woolley, Ian, Lau, Jillian S. Y.

“…Background: Little is known about the impacts at an individual level of long-term antibiotic consumption. We explored health outcomes of long-term antibiotic…”
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Assessing understandings and perceptions of HIV cure among peer navigators and treatment officers in Australia Autor Lau, Jillian S. Y., Clifton, Brent, Rule, John, Ellard, Jeanne, McMahon, James H.

“…HIV community peer navigators and treatment officers are important sources of information and guidance for people living with HIV. We conducted an anonymous…”
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Reductions in Antibiotic Prescribing in Australia During the Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic: National Prescribing Data Autor Skeggs, Jack, MacPhail, Aleece, Korman, Tony, Woolley, Ian, Lau, Jillian S Y

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Life-long antimicrobial therapy: where is the evidence? Autor Lau, Jillian S Y, Korman, Tony M, Woolley, Ian

“…The decision to prescribe long-term or 'life-long' antibiotics in patients requires careful consideration by the treating clinician. While several guidelines…”
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Balancing Statistical Power and Risk in HIV Cure Clinical Trial Design Autor Lau, Jillian S Y, Cromer, Deborah, Pinkevych, Mykola, Lewin, Sharon R, Rasmussen, Thomas A, McMahon, James H, Davenport, Miles P

“…Abstract Background Analytical treatment interruptions (ATI) are pauses of antiretroviral therapy (ART) in the context of human immunodeficiency virus (HIV)…”
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Clinical trials of antiretroviral treatment interruption in HIV-infected individuals Autor Lau, Jillian S Y, Smith, Miranda Z, Lewin, Sharon R, McMahon, James H

“…: Despite the benefits of antiretroviral therapy (ART) for people living with HIV, there has been a long-standing research interest in interrupting ART as a…”
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The impact of immune checkpoint therapy on the latent reservoir in HIV infected individuals with cancer on antiretroviral therapy Autor Lau, Jillian S Y, McMahon, James H, Gubser, Celine, Solomon, Ajantha, Chiu, Chris Y H, Dantanarayana, Ashanti, Chea, Socheata, Tennakoon, Surekha, Zerbato, Jennifer M, Garlick, Jill, Morcilla, Vincent, Palmer, Sarah, Lewin, Sharon R, Rasmussen, Thomas A

“…To quantify HIV specific immunological and virological changes in people living with HIV (PLWH) on antiretroviral therapy (ART) with malignancy who received…”
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Perspectives on Analytical Treatment Interruptions in People Living with HIV and Their Health Care Providers in the Landscape of HIV Cure-Focused Studies Autor Lau, Jillian S Y, Smith, Miranda Z, Allan, Brent, Martinez, Cipriano, Power, Jennifer, Lewin, Sharon R, McMahon, James H

“…Analytical treatment interruptions (ATIs) aim to assess effects of HIV cure-focused interventions, but poses potential risks. Understanding of ATI…”
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Barriers and strategies to achieve a cure for HIV Autor Pitman, Matthew C, Lau, Jillian S Y, McMahon, James H, Lewin, Sharon R

“…9 years since the report of a cure for HIV after C-C chemokine receptor type 5 Δ32 stem cell transplantation, no other case of HIV cure has been reported,…”
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The role of analytical treatment interruptions in shaping HIV-specific immunity and HIV cure Autor Weerasuria, Mihiri, McMahon, James H, Lewin, Sharon R, Lau, Jillian S Y

“…While existing guidance supports the use of analytical treatment interruptions (ATIs) in HIV cure clinical trials, their design must be tailored to the…”
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Cutting Edge: SARS-CoV-2 Infection Induces Robust Germinal Center Activity in the Human Tonsil Autor Tan, Hyon-Xhi, Wragg, Kathleen M, Kelly, Hannah G, Esterbauer, Robyn, Dixon, Benjamin J, Lau, Jillian S Y, Flanagan, Katie L, van de Sandt, Carolien E, Kedzierska, Katherine, McMahon, James H, Wheatley, Adam K, Juno, Jennifer A, Kent, Stephen J

“…Understanding the generation of immunity to SARS-CoV-2 in lymphoid tissues draining the site of infection has implications for immunity to SARS-CoV-2. We…”
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Human immunodeficiency virus and solid organ transplantation: a 15‐year retrospective audit at a tertiary Australian transplant centre Autor Griffin, David W. J., Kotecha, Sakhee, Basu, Gopal, Gow, Paul, Lau, Jillian S. Y., Morrissey, Catherine O., Hoy, Jennifer F.

“…Background The incidence of end‐stage organ disease in people living with human immunodeficiency virus (HIV) (PLWH) is increasing, as people live longer due to…”
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Neurotoxicity with high-dose disulfiram and vorinostat used for HIV latency reversal Autor McMahon, James H, Evans, Vanessa A, Lau, Jillian S Y, Symons, Jori, Zerbato, Jennifer M, Chang, Judy, Solomon, Ajantha, Tennakoon, Surekha, Dantanarayana, Ashanti, Hagenauer, Michelle, Lee, Sulggi, Palmer, Sarah, Fisher, Katie, Bumpus, Namandje, Heck, Carley J S, Burger, David, Wu, Guoxin, Zuck, Paul, Howell, Bonnie J, Zetterberg, Henrik H, Blennow, Kaj, Gisslen, Magnus, Rasmussen, Thomas A, Lewin, Sharon R

“…The aim of this study was to examine whether administering both vorinostat and disulfiram to people with HIV (PWH) on antiretroviral therapy (ART) is well…”
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