Suchergebnisse - "Lash, G E"

Interleukin-34 is present at the fetal-maternal interface and induces immunoregulatory macrophages of a decidual phenotype in vitro von Lindau, R, Mehta, R B, Lash, G E, Papapavlou, G, Boij, R, Berg, G, Jenmalm, M C, Ernerudh, J, Svensson-Arvelund, J

“… Is the newly discovered cytokine interleukin (IL)-34 expressed at the human fetal-maternal interface in order to influence polarization of monocytes into …”
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Tumour cell dissemination following endoscopic stent insertion von Maruthachalam, K., Lash, G. E., Shenton, B. K., Horgan, A. F.

“… Background: This study examined whether colonoscopy or endoscopic stent insertion increases levels of carcinoembryonic antigen (CEA) and/or cytokeratin (CK) 20 …”
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Effects of local decidua on trophoblast invasion and spiral artery remodeling in focal placenta creta – An immunohistochemical study von Hannon, T., Innes, B.A., Lash, G.E., Bulmer, J.N., Robson, S.C.

“… Placenta creta is an increasingly prevalent cause of maternal morbidity/mortality. Decidua is at least focally defective and extravillous trophoblast (EVT) may …”
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Role of Interleukin 8 in Uterine Natural Killer Cell Regulation of Extravillous Trophoblast Cell Invasion von De Oliveira, L.G., Lash, G.E., Murray-Dunning, C., Bulmer, J.N., Innes, B.A., Searle, R.F., Sass, N., Robson, S.C.

“… Extravillous trophoblast cell (EVT) invasion of maternal tissues is critical for successful pregnancy. Decidual factors, including uterine natural killer (uNK) …”
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Localization of Angiogenic Growth Factors and Their Receptors in the Human Placental Bed Throughout Normal Human Pregnancy von Schiessl, B., Innes, B.A., Bulmer, J.N., Otun, H.A., Chadwick, T.J., Robson, S.C., Lash, G.E.

“… During early human pregnancy invasion of uterine spiral arteries by extravillous trophoblast cells contributes to their remodelling characterised by loss of …”
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Triiodothyronine regulates angiogenic growth factor and cytokine secretion by isolated human decidual cells in a cell-type specific and gestational age-dependent manner von Vasilopoulou, E., Loubière, L.S., Lash, G.E., Ohizua, O., McCabe, C.J., Franklyn, J.A., Kilby, M.D., Chan, S.Y.

“… STUDY QUESTION Does triiodothyronine (T3) regulate the secretion of angiogenic growth factors and cytokines by human decidual cells isolated from early …”
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Secretion of Angiogenic Growth Factors by Villous Cytotrophoblast and Extravillous Trophoblast in Early Human Pregnancy von Lash, G.E., Naruse, K., Innes, B.A., Robson, S.C., Searle, R.F., Bulmer, J.N.

“… Angiogenesis is a key feature of placental and uterine development in early pregnancy. We hypothesized that trophoblast cells produce angiogenic growth …”
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Uterine spiral artery muscle dedifferentiation von Robson, A, Lash, G E, Innes, B A, Zhang, J Y, Robson, S C, Bulmer, J N

“… Is vascular smooth muscle cell (VSMC) dedifferentiation a feature of uterine spiral artery (SpA) remodelling in early human pregnancy? Remodelling of human …”
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The Urokinase Plasminogen Activator (uPA) System in Uterine Natural Killer Cells in the Placental Bed During Early Pregnancy von Naruse, K., Lash, G.E., Bulmer, J.N., Innes, B.A., Otun, H.A., Searle, R.F., Robson, S.C.

“… The urokinase plasminogen activator (uPA) system plays pivotal roles in cell invasion, adhesion and migration. Roles for uterine natural killer (uNK) cells in …”
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Maternal plasma and amniotic fluid angiogenic factors and their receptors in monochorionic twin pregnancies complicated by twin‐to‐twin transfusion syndrome von Fox, C. E., Lash, G. E., Pretlove, S. J., Chan, B. C., Holder, R., Kilby, M. D.

“… Objective Angiogenic factors play a role in human placentation and may be aberrant in severe twin‐to‐twin transfusion syndrome (TTTS). The aim of this study …”
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Effect of Low Oxygen Concentrations on Trophoblast-Like Cell Line Invasion von Lash, G.E., Hornbuckle, J., Brunt, A., Kirkley, M., Searle, R.F., Robson, S.C., Bulmer, J.N.

“… The applicability of trophoblast-like cell lines to the study of trophoblast function has been widely debated. The present study investigated the effect of …”
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Altered decidual and placental catabolism of vitamin D may contribute to the aetiology of spontaneous miscarriage von Hou, H., Zhang, J.Y., Chen, D., Deng, F., Morse, A.N., Qiu, X., He, P., Lash, G.E.

“… Vitamin D catabolizing enzymes, along with vitamin D receptor (VDR) and vitamin D binding protein (DBP) are expressed in the decidua and placenta during …”
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Review: Functional role of uterine natural killer (uNK) cells in human early pregnancy decidua von Lash, G.E., Robson, S.C., Bulmer, J.N.

“… Leukocytes comprise approximately 30–40% of decidual stromal cells in early human pregnancy. The major leukocyte component is the uterine natural killer (uNK) …”
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Regulation of Trophoblast Invasion — A Workshop Report von Knöfler, M., Simmons, D.G., Lash, G.E., Harris, L.K., Armant, D.R.

“… Trophoblast invasion during placental development helps to establish efficient physiological exchange between maternal and fetal circulatory systems …”
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Regulation of extravillous trophoblast invasion by uterine natural killer cells is dependent on gestational age von Lash, Gendie E, Otun, Harry A, Innes, Barbara A, Percival, Kathryn, Searle, Roger F, Robson, Stephen C, Bulmer, Judith N

“… Extravillous trophoblast (EVT) cell invasion of uterine decidua and the inner third of myometrium is critical for successful pregnancy. Many decidual factors …”
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Relationship between tissue damage and heme oxygenase expression in chorionic villi of term human placenta von Lash, G E, McLaughlin, B E, MacDonald-Goodfellow, S K, Smith, G N, Brien, J F, Marks, G S, Nakatsu, K, Graham, C H

“… Heme oxygenase (HO) catalyzes the oxidation of heme to carbon monoxide (CO), biliverdin, and iron and is thought to play a role in protecting tissues from …”
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Quantification of spiral artery remodelling using an Adobe Photoshop-based technique von Otun, H A, Innes, B A, Lash, G E, Schiessl, B, Ball, E, Searle, R F, Robson, S C, Bulmer, J N

“… Uterine spiral arteries undergo remodelling in normal pregnancy, with replacement of the musculoelastic arterial media by fibrinoid containing extravillous …”
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Localization of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitors for MMPs (TIMPs) in uterine natural killer cells in early human pregnancy von Naruse, Katsuhiko, Lash, Gendie E, Innes, Barbara A, Otun, Harry A, Searle, Roger F, Robson, Stephen C, Bulmer, Judith N

“… Invasion by extravillous trophoblast into uterine decidua and myometrium with remodeling of spiral arteries is essential for normal human pregnancy and is …”
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The Effects of Angiogenic Growth Factors on Extravillous Trophoblast Invasion and Motility von Lash, G.E, Cartwright, J.E, Whitley, G.St J, Trew, A.J, Baker, P.N

“… There is accumulating evidence that deficient trophoblast invasion of the placental bed spiral arteries is crucial to the pathogenesis of pre-eclampsia and …”
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Gestational Diseases — A Workshop Report von Lash, G.E., Quenby, S., Burton, G.J., Nakashima, A., Kamat, B.R., Ray, J., Bulmer, J.N.

“… Between 11% and 20% of all clinically recognised pregnancies are lost before the 20th week of gestation, with huge financial and personal implications. Immune …”
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