Výsledky vyhľadávania - "Landmesser, Ulf"

Tissue factor as a link between inflammation and coagulation Autor Witkowski, Marco, Landmesser, Ulf, Rauch, Ursula

“…Due to its receptor activity for factor VII, tissue factor (TF) is primary initiator of the blood coagulation cascade and ensures rapid hemostasis in case of…”
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Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis Autor Stone, Gregg W, Christiansen, Evald H, Ali, Ziad A, Andreasen, Lene N, Maehara, Akiko, Ahmad, Yousif, Landmesser, Ulf, Holm, Niels R

“…Previous meta-analyses have shown reduced risks of composite adverse events with intravascular imaging-guided percutaneous coronary intervention (PCI) compared…”
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Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives Autor Poller, Wolfgang, Dimmeler, Stefanie, Heymans, Stephane, Zeller, Tanja, Haas, Jan, Karakas, Mahir, Leistner, David-Manuel, Jakob, Philipp, Nakagawa, Shinichi, Blankenberg, Stefan, Engelhardt, Stefan, Thum, Thomas, Weber, Christian, Meder, Benjamin, Hajjar, Roger, Landmesser, Ulf

“…Recent research has demonstrated that the non-coding genome plays a key role in genetic programming and gene regulation during development as well as in health…”
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Metabolomic profiles predict individual multidisease outcomes Autor Buergel, Thore, Steinfeldt, Jakob, Ruyoga, Greg, Pietzner, Maik, Bizzarri, Daniele, Vojinovic, Dina, Upmeier zu Belzen, Julius, Loock, Lukas, Kittner, Paul, Christmann, Lara, Hollmann, Noah, Strangalies, Henrik, Braunger, Jana M., Wild, Benjamin, Chiesa, Scott T., Spranger, Joachim, Klostermann, Fabian, van den Akker, Erik B., Trompet, Stella, Mooijaart, Simon P., Sattar, Naveed, Jukema, J. Wouter, Lavrijssen, Birgit, Kavousi, Maryam, Ghanbari, Mohsen, Ikram, Mohammad A., Slagboom, Eline, Kivimaki, Mika, Langenberg, Claudia, Deanfield, John, Eils, Roland, Landmesser, Ulf

“…Risk stratification is critical for the early identification of high-risk individuals and disease prevention. Here we explored the potential of nuclear…”
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Inclisiran and cardiovascular events: a patient-level analysis of phase III trials Autor Ray, Kausik K, Raal, Frederick J, Kallend, David G, Jaros, Mark J, Koenig, Wolfgang, Leiter, Lawrence A, Landmesser, Ulf, Schwartz, Gregory G, Lawrence, David, Friedman, Andrew, Garcia Conde, Lorena, Wright, R Scott

“…Inclisiran, an siRNA administered twice-yearly, significantly reduced LDL cholesterol (LDL-C) in Phase III trials. Whether lowering LDL-C with inclisiran…”
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Inclisiran in Patients at High Cardiovascular Risk with Elevated LDL Cholesterol Autor Ray, Kausik K, Landmesser, Ulf, Leiter, Lawrence A, Kallend, David, Dufour, Robert, Karakas, Mahir, Hall, Tim, Troquay, Roland P.T, Turner, Traci, Visseren, Frank L.J, Wijngaard, Peter, Wright, R. Scott, Kastelein, John J.P

“…Inclisiran, a small interfering RNA that targets PCSK9 mRNA, was given as a single injection at baseline or in two doses at baseline and 90 days. At 180 days,…”
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Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation Autor Desch, Steffen, Freund, Anne, Akin, Ibrahim, Behnes, Michael, Preusch, Michael R, Zelniker, Thomas A, Skurk, Carsten, Landmesser, Ulf, Graf, Tobias, Eitel, Ingo, Fuernau, Georg, Haake, Hendrik, Nordbeck, Peter, Hammer, Fabian, Felix, Stephan B, Hassager, Christian, Engstrøm, Thomas, Fichtlscherer, Stephan, Ledwoch, Jakob, Lenk, Karsten, Joner, Michael, Steiner, Stephan, Liebetrau, Christoph, Voigt, Ingo, Zeymer, Uwe, Brand, Michael, Schmitz, Roland, Horstkotte, Jan, Jacobshagen, Claudius, Pöss, Janine, Abdel-Wahab, Mohamed, Lurz, Philipp, Jobs, Alexander, de Waha-Thiele, Suzanne, Olbrich, Denise, Sandig, Frank, König, Inke R, Brett, Sabine, Vens, Maren, Klinge, Kathrin, Thiele, Holger

“…In this randomized trial involving patients with out-of-hospital cardiac arrest without ST-segment elevation on postresuscitation electrocardiography, no…”
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Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel Autor Borén, Jan, Chapman, M John, Krauss, Ronald M, Packard, Chris J, Bentzon, Jacob F, Binder, Christoph J, Daemen, Mat J, Demer, Linda L, Hegele, Robert A, Nicholls, Stephen J, Nordestgaard, Børge G, Watts, Gerald F, Bruckert, Eric, Fazio, Sergio, Ference, Brian A, Graham, Ian, Horton, Jay D, Landmesser, Ulf, Laufs, Ulrich, Masana, Luis, Pasterkamp, Gerard, Raal, Frederick J, Ray, Kausik K, Schunkert, Heribert, Taskinen, Marja-Riitta, van de Sluis, Bart, Wiklund, Olov, Tokgozoglu, Lale, Catapano, Alberico L, Ginsberg, Henry N

“…Abstract…”
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Optical Coherence Tomography–Guided versus Angiography-Guided PCI Autor Ali, Ziad A., Landmesser, Ulf, Maehara, Akiko, Matsumura, Mitsuaki, Shlofmitz, Richard A., Guagliumi, Giulio, Price, Matthew J., Hill, Jonathan M., Akasaka, Takashi, Prati, Francesco, Bezerra, Hiram G., Wijns, William, Leistner, David, Canova, Paolo, Alfonso, Fernando, Fabbiocchi, Franco, Dogan, Ozgen, McGreevy, Robert J., McNutt, Robert W., Nie, Hong, Buccola, Jana, West, Nick E.J., Stone, Gregg W.

“…In a randomized trial, optical coherence tomography–guided PCI resulted in a larger minimum stent area than angiography-guided PCI, but there was no…”
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Transcatheter or Surgical Treatment of Aortic-Valve Stenosis Autor Blankenberg, Stefan, Seiffert, Moritz, Vonthein, Reinhard, Baumgartner, Helmut, Bleiziffer, Sabine, Borger, Michael A., Choi, Yeong-Hoon, Clemmensen, Peter, Cremer, Jochen, Czerny, Martin, Diercks, Nina, Eitel, Ingo, Ensminger, Stephan, Frank, Derk, Frey, Norbert, Hagendorff, Andreas, Hagl, Christian, Hamm, Christian, Kappert, Utz, Karck, Matthias, Kim, Won-Keun, König, Inke R., Krane, Markus, Landmesser, Ulf, Linke, Axel, Maier, Lars S., Massberg, Steffen, Neumann, Franz-Josef, Reichenspurner, Hermann, Rudolph, Tanja K., Schmid, Christof, Thiele, Holger, Twerenbold, Raphael, Walther, Thomas, Westermann, Dirk, Xhepa, Erion, Ziegler, Andreas, Falk, Volkmar

“…A randomized trial that enrolled patients with severe aortic stenosis at low or intermediate surgical risk showed that transcatheter aortic-valve implantation…”
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HDL and coronary heart disease—novel insights Autor Landmesser, Ulf

“…The association between HDL cholesterol and cardiovascular events, and the potential antiatherogenic effects of HDL particles, are altered in patients with…”
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Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel Autor Ference, Brian A, Ginsberg, Henry N, Graham, Ian, Ray, Kausik K, Packard, Chris J, Bruckert, Eric, Hegele, Robert A, Krauss, Ronald M, Raal, Frederick J, Schunkert, Heribert, Watts, Gerald F, Borén, Jan, Fazio, Sergio, Horton, Jay D, Masana, Luis, Nicholls, Stephen J, Nordestgaard, Børge G, van de Sluis, Bart, Taskinen, Marja-Riitta, Tokgözoglu, Lale, Landmesser, Ulf, Laufs, Ulrich, Wiklund, Olov, Stock, Jane K, Chapman, M John, Catapano, Alberico L

“…To appraise the clinical and genetic evidence that low-density lipoproteins (LDLs) cause atherosclerotic cardiovascular disease (ASCVD). We assessed whether…”
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Pooled Patient-Level Analysis of Inclisiran Trials in Patients With Familial Hypercholesterolemia or Atherosclerosis Autor Wright, R Scott, Ray, Kausik K, Raal, Frederick J, Kallend, David G, Jaros, Mark, Koenig, Wolfgang, Leiter, Lawrence A, Landmesser, Ulf, Schwartz, Gregory G, Friedman, Andrew, Wijngaard, Peter L J, Garcia Conde, Lorena, Kastelein, John J P

“…Inclisiran is a double-stranded small interfering RNA that suppresses proprotein convertase subtilisin-kexin type 9 (PCSK9) translation in the liver, leading…”
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Neurological update: use of cardiac troponin in patients with stroke Autor Scheitz, Jan F., Stengl, Helena, Nolte, Christian H., Landmesser, Ulf, Endres, Matthias

“…Cardiac troponin is a specific and sensitive biomarker to identify and quantify myocardial injury. Myocardial injury is frequently detected after acute…”
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Into the Wild: GWAS Exploration of Non-coding RNAs Autor Giral, Hector, Landmesser, Ulf, Kratzer, Adelheid

“…Genome-wide association studies (GWAS) have proven a fundamental tool to identify common variants associated to complex traits, thus contributing to unveil the…”
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Comparison of newer generation self-expandable vs. balloon-expandable valves in transcatheter aortic valve implantation: the randomized SOLVE-TAVI trial Autor Thiele, Holger, Kurz, Thomas, Feistritzer, Hans-Josef, Stachel, Georg, Hartung, Philipp, Eitel, Ingo, Marquetand, Christoph, Nef, Holger, Doerr, Oliver, Lauten, Alexander, Landmesser, Ulf, Abdel-Wahab, Mohamed, Sandri, Marcus, Holzhey, David, Borger, Michael, Ince, Hüseyin, Öner, Alper, Meyer-Saraei, Roza, Wienbergen, Harm, Fach, Andreas, Frey, Norbert, König, Inke R, Vonthein, Reinhard, Rückert, Yvonne, Funkat, Anne-Kathrin, de Waha-Thiele, Suzanne, Desch, Steffen

“…Transcatheter aortic valve implantation (TAVI) has emerged as established treatment option in patients with symptomatic aortic stenosis. Technical developments…”
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2017 EACTS Guidelines on perioperative medication in adult cardiac surgery Autor Sousa-Uva, Miguel, Head, Stuart J, Milojevic, Milan, Collet, Jean-Philippe, Landoni, Giovanni, Castella, Manuel, Dunning, Joel, Gudbjartsson, Tómas, Linker, Nick J, Sandoval, Elena, Thielmann, Matthias, Jeppsson, Anders, Landmesser, Ulf

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Impact of oral anticoagulation on clinical outcomes of COVID-19: a nationwide cohort study of hospitalized patients in Germany Autor Fröhlich, Georg M., Jeschke, Elke, Eichler, Uwe, Thiele, Holger, Alhariri, Laila, Reinthaler, Markus, Kastrati, Adnan, Leistner, David Manuel, Skurk, Carsten, Landmesser, Ulf, Günster, Christian

“…Objectives The aim of this study was to investigate the impact of concomitant long-term medication—with a focus on ACE inhibitors and oral anticoagulation—on…”
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Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges Autor Tongers, Jörn, Losordo, Douglas W, Landmesser, Ulf

“…In the absence of effective endogenous repair mechanisms after cardiac injury, cell-based therapies have rapidly emerged as a potential novel therapeutic…”
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Effect of inclisiran, the small-interfering RNA against proprotein convertase subtilisin/kexin type 9, on platelets, immune cells, and immunological biomarkers: a pre-specified analysis from ORION-1 Autor Landmesser, Ulf, Haghikia, Arash, Leiter, Lawrence A, Wright, R Scott, Kallend, David, Wijngaard, Peter, Stoekenbroek, Robert, Kastelein, John Jp, Ray, Kausik K

“…Small-interfering RNA (siRNA)-based targeting of proprotein convertase subtilisin/kexin type 9 (PCSK9) represents a novel therapeutic approach that may provide…”
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