Výsledky vyhľadávania - "Kritski, Afranio"

Strengthening Multidrug-Resistant Tuberculosis Epidemiological Surveillance in Rio de Janeiro: a multidimensional analysis Autor Bhering, Marcela, Kritski, Afrânio

“…This study aimed to reinforce the importance of the epidemiological surveillance of multidrug-resistant tuberculosis (MDR-TB) in Rio de Janeiro State (RJ)…”
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Predictive factors for unfavourable treatment in MDR-TB and XDR-TB patients in Rio de Janeiro State, Brazil, 2000-2016 Autor Bhering, Marcela, Duarte, Raquel, Kritski, Afrânio

“…The State of Rio de Janeiro stands out as having the second highest incidence and the highest mortality rate due to TB in Brazil. This study aims at…”
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Primary and acquired multidrug-resistant tuberculosis: Predictive factors for unfavorable treatment outcomes in Rio de Janeiro, 2000–2016 Autor Bhering, Marcela, Kritski, Afrânio

“…Objective. To identify clinical and demographic factors associated with unfavorable treatment outcomes in patients with primary and acquired…”
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Trends in primary multidrug-resistant tuberculosis in the State of Rio de Janeiro: a retrospective study conducted during 2000-2019 Autor Bhering, Marcela, Kritski, Afrânio

“…We analyzed the trends in primary multidrug-resistant tuberculosis (MDR-TB). We performed a time series analysis of primary MDR-TB cases reported in the State…”
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Cost-effectiveness of newer technologies for the diagnosis of Mycobacterium tuberculosis infection in Brazilian people living with HIV Autor Steffen, Ricardo E., Pinto, Marcia, Kritski, Afranio, Trajman, Anete

“…Tuberculosis is the leading cause of death among people living with HIV (PLH). Preventive tuberculosis therapy reduces mortality in PLH, especially in those…”
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Tuberculosis Treatment Outcomes in Brazil: Different Predictors for Each Type of Unsuccessful Outcome Autor Ridolfi, Felipe, Peetluk, Lauren, Amorim, Gustavo, Turner, Megan, Figueiredo, Marina, Cordeiro-Santos, Marcelo, Cavalcante, Solange, Kritski, Afrânio, Durovni, Betina, Andrade, Bruno, Sterling, Timothy R, Rolla, Valeria

“…Successful tuberculosis (TB) treatment is necessary for disease control. The World Health Organization (WHO) has a target TB treatment success rate of ≥90%. We…”
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Barriers faced by patients in the diagnosis of multidrug-resistant tuberculosis in Brazil Autor Bhering, Marcela, Dalcolmo, Margareth, Sarubbi Júnior, Vicente, Kritski, Afrânio

“…OBJECTIVE To understand patients’ narratives about the barriers they faced in the diagnosis and treatment of multidrug-resistant tuberculosis, and their…”
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Novel stepwise approach to assess representativeness of a large multicenter observational cohort of tuberculosis patients: The example of RePORT Brazil Autor Arriaga, María B., Amorim, Gustavo, Queiroz, Artur T.L., Rodrigues, Moreno M.S., Araújo-Pereira, Mariana, Nogueira, Betania M.F., Souza, Alexandra Brito, Rocha, Michael S., Benjamin, Aline, Moreira, Adriana S.R., de Oliveira, Jamile G., Figueiredo, Marina C., Turner, Megan M., Alves, Kleydson, Durovni, Betina, Lapa-e-Silva, José R., Kritski, Afrânio L., Cavalcante, Solange, Rolla, Valeria C., Cordeiro-Santos, Marcelo, Sterling, Timothy R., Andrade, Bruno B.

“…•The representativeness of a large TB cohort was tested using the Brazilian National TB databank.•The novel analysis of second-generation p-values uncovered…”
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Unfavorable Outcomes in Tuberculosis: Multidimensional Factors among Adolescents in Rio de Janeiro, Brazil Autor de Oliveira, Marcia C B, Sant'Anna, Clemax C, Raggio Luiz, Ronir, Kritski, Afrânio L

“…Since 2018, adolescents have been included as a target group for tuberculosis (TB) surveillance by the WHO. However, they are considered a neglected…”
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The Effect of Diabetes and Prediabetes on Antituberculosis Treatment Outcomes: A Multicenter Prospective Cohort Study Autor Arriaga, María B, Araújo-Pereira, Mariana, Barreto-Duarte, Beatriz, Nogueira, Betânia, Freire, Maria Vitória C N S, Queiroz, Artur T L, Rodrigues, Moreno M S, Rocha, Michael S, Souza, Alexandra B, Spener-Gomes, Renata, Carvalho, Anna Cristina C, Figueiredo, Marina C, Turner, Megan M, Durovni, Betina, Lapa-E-Silva, José R, Kritski, Afrânio L, Cavalcante, Solange, Rolla, Valeria C, Cordeiro-Santos, Marcelo, Sterling, Timothy R, Andrade, Bruno B

“…It is unclear whether diabetes or prediabetes affects unfavorable treatment outcomes and death in people with tuberculosis (PWTB). Culture-confirmed,…”
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Pharmacogenetics of tuberculosis treatment toxicity and effectiveness in a large Brazilian cohort Autor Amorim, Gustavo, Jaworski, James, Yang, Jing, Cordeiro-Santos, Marcelo, Kritski, Afrânio L, Figueiredo, Marina C, Turner, Megan, Andrade, Bruno B, Velez Edwards, Digna R, Santos, Adalberto R, Rolla, Valeria C, Sterling, Timothy R, Haas, David W

“…Genetic polymorphisms have been associated with risk of antituberculosis treatment toxicity. We characterized associations with adverse events and treatment…”
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Moxifloxacin versus ethambutol in the initial treatment of tuberculosis: a double-blind, randomised, controlled phase II trial Autor Conde, Marcus B, Efron, Anne, Loredo, Carla, De Souza, Gilvan R Muzy, Graça, Nadja P, Cezar, Michelle C, Ram, Malathi, Chaudhary, Mohammad A, Bishai, William R, Kritski, Afranio L, Chaisson, Richard E

“…New treatments are needed to shorten the time required to cure tuberculosis and to treat drug-resistant strains. The fluoroquinolone moxifloxacin is a…”
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Hypervirulent Mycobacterium tuberculosis strain triggers necrotic lung pathology associated with enhanced recruitment of neutrophils in resistant C57BL/6 mice Autor Almeida, Fabrício M., Ventura, Thatiana L. B., Amaral, Eduardo P., Ribeiro, Simone C. M., Calixto, Sanderson D., Manhães, Marcelle R., Rezende, Andreza L., Souzal, Giliane S., de Carvalho, Igor S., Silva, Elisangela C., Silva, Juliana Azevedo da, Carvalho, Eulógio C. Q., Kritski, Afranio L., Lasunskaia, Elena B.

“…Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) that in most cases induces irreversible necrosis of lung tissue as…”
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Sustained elevated levels of C-reactive protein and ferritin in pulmonary tuberculosis patients remaining culture positive upon treatment initiation Autor Miranda, Pryscila, Gil-Santana, Leonardo, Oliveira, Marina G., Mesquita, Eliene D. D., Silva, Elisangela, Rauwerdink, Anneloek, Cobelens, Frank, Oliveira, Martha M., Andrade, Bruno B., Kritski, Afrânio

“…Clinical trials that evaluate new anti-tubercular drugs and treatment regimens take years to complete due to the slow clearance of Mycobacterium tuberculosis…”
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Learning from the Italian experience in coping with COVID-19 Autor Carvalho, Anna Cristina Calçada, Kritski, Afrânio

“…In March 2020, the rapid increase in COVID-19 cases overburdened the Italian health system, with the country becoming the pandemic's epicenter. We present a…”
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Treatment outcomes of MDR-tuberculosis patients in Brazil: a retrospective cohort analysis Autor Bastos, Mayara Lisboa, Cosme, Lorrayne Beliqui, Fregona, Geisa, do Prado, Thiago Nascimento, Bertolde, Adelmo Inácio, Zandonade, Eliana, Sanchez, Mauro N., Dalcolmo, Margareth Pretti, Kritski, Afrânio, Trajman, Anete, Maciel, Ethel Leonor Noia

“…Background Multidrug-resistant tuberculosis (MDR-TB) is a threat for the global TB epidemic control. Despite existing evidence that individualized treatment of…”
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Tuberculosis-associated anemia is linked to a distinct inflammatory profile that persists after initiation of antitubercular therapy Autor Gil-Santana, Leonardo, Cruz, Luís A. B., Arriaga, María B., Miranda, Pryscila F. C., Fukutani, Kiyoshi F., Silveira-Mattos, Paulo S., Silva, Elisangela C., Oliveira, Marina G., Mesquita, Eliene D. D., Rauwerdink, Anneloek, Cobelens, Frank, Oliveira, Martha M., Kritski, Afranio, Andrade, Bruno B.

“…Pulmonary tuberculosis (PTB) is associated with chronic inflammation and anemia. How anemia impacts systemic inflammation in PTB patients undergoing…”
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Body Mass Index and Incident Tuberculosis in Close Tuberculosis Contacts Autor Arriaga, María B, Amorim, Gustavo, Figueiredo, Marina C, Staats, Cody, Kritski, Afrânio L, Cordeiro-Santo, Marcelo, Rolla, Valeria C, Rebeiro, Peter F, Andrade, Bruno B, Sterling, Timothy R

“…Approximately 95% of people infected with M. tuberculosis do not progress to tuberculosis (TB) disease. Identifying key determinants of TB progression could…”
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Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil Autor Verza, Mirela, Scheffer, Mara Cristina, Salvato, Richard Steiner, Schorner, Marcos André, Barazzetti, Fernando Hartmann, Machado, Hanalydia de Melo, Medeiros, Taiane Freitas, Rovaris, Darcita Buerger, Portugal, Isabel, Viveiros, Miguel, Perdigão, João, Kritski, Afrânio, Bazzo, Maria Luiza

“…Mycobacterium tuberculosis ( M.tb ), the pathogen responsible for tuberculosis (TB) poses as the major cause of death among infectious diseases. The knowledge…”
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Transcriptomic Signatures of Progression to Tuberculosis Disease Among Close Contacts in Brazil Autor Mendelsohn, Simon C, Andrade, Bruno B, Mbandi, Stanley Kimbung, Andrade, Alice M S, Muwanga, Vanessa M, Figueiredo, Marina C, Erasmus, Mzwandile, Rolla, Valeria C, Thami, Prisca K, Cordeiro-Santos, Marcelo, Penn-Nicholson, Adam, Kritski, Afranio L, Hatherill, Mark, Sterling, Timothy R, Scriba, Thomas J

“…Abstract Background Approximately 5% of people infected with Mycobacterium tuberculosis progress to tuberculosis (TB) disease without preventive therapy. There…”
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