Výsledky vyhľadávania - "Kondapalli, Chandana"

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65 Autor Kazlauskaite, Agne, Kondapalli, Chandana, Gourlay, Robert, Campbell, David G, Ritorto, Maria Stella, Hofmann, Kay, Alessi, Dario R, Knebel, Axel, Trost, Matthias, Muqit, Miratul M K

“…We have previously reported that the Parkinson's disease-associated kinase PINK1 (PTEN-induced putative kinase 1) is activated by mitochondrial depolarization…”
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Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy Autor Lee, Annie, Kondapalli, Chandana, Virga, Daniel M., Lewis, Tommy L., Koo, So Yeon, Ashok, Archana, Mairet-Coello, Georges, Herzig, Sebastien, Foretz, Marc, Viollet, Benoit, Shaw, Reuben, Sproul, Andrew, Polleux, Franck

“…During the early stages of Alzheimer’s disease (AD) in both mouse models and human patients, soluble forms of Amyloid-β 1–42 oligomers (Aβ42o) trigger loss of…”
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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65 Autor Kondapalli, Chandana, Kazlauskaite, Agne, Zhang, Ning, Woodroof, Helen I., Campbell, David G., Gourlay, Robert, Burchell, Lynn, Walden, Helen, Macartney, Thomas J., Deak, Maria, Knebel, Axel, Alessi, Dario R., Muqit, Miratul M. K.

“…Missense mutations in PTEN-induced kinase 1 (PINK1) cause autosomal-recessive inherited Parkinson's disease (PD). We have exploited our recent discovery that…”
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Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1 Autor Lai, Yu-Chiang, Kondapalli, Chandana, Lehneck, Ronny, Procter, James B, Dill, Brian D, Woodroof, Helen I, Gourlay, Robert, Peggie, Mark, Macartney, Thomas J, Corti, Olga, Corvol, Jean-Christophe, Campbell, David G, Itzen, Aymelt, Trost, Matthias, Muqit, Miratul MK

“…Mutations in the PTEN‐induced kinase 1 (PINK1) are causative of autosomal recessive Parkinson's disease (PD). We have previously reported that PINK1 is…”
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The linker region in receptor guanylyl cyclases is a key regulatory module: mutational analysis of guanylyl cyclase C Autor Saha, Sayanti, Biswas, Kabir Hassan, Kondapalli, Chandana, Isloor, Nishitha, Visweswariah, Sandhya S

“…Receptor guanylyl cyclases are multidomain proteins, and ligand binding to the extracellular domain increases the levels of intracellular cGMP. The…”
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Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1 Autor Lai, Yu‐Chiang, Kondapalli, Chandana, Lehneck, Ronny, Procter, James B, Dill, Brian D, Woodroof, Helen I, Gourlay, Robert, Peggie, Mark, Macartney, Thomas J, Corti, Olga, Corvol, Jean‐Christophe, Campbell, David G, Itzen, Aymelt, Trost, Matthias, Muqit, Miratul MK

“…Mutations in the PTEN ‐induced kinase 1 ( PINK 1) are causative of autosomal recessive Parkinson's disease ( PD ). We have previously reported that PINK 1 is…”
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Investigation of regulation and downstream signaling pathway of parkinson's disease associated kinase, pink1 Autor Kondapalli, Chandana

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Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy Autor Lee, Annie, Kondapalli, Chandana, Virga, Daniel M, Lewis, Tommy L, Koo, So Yeon, Ashok, Archana, Mairet-Coello, Georges, Herzig, Sebastien, Shaw, Reuben, Sproul, Andrew, Polleux, Franck

“…During the early stages of Alzheimer's disease (AD) in both mouse models and human patients, soluble forms of Amyloidβ1-42 oligomers (Aβ42o) trigger loss of…”
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