Výsledky vyhľadávania - "Kobinger, Gary"

Plant-made vaccines and therapeutics Autor Fausther-Bovendo, Hugues, Kobinger, Gary

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Pre-existing immunity against Ad vectors: Humoral, cellular, and innate response, what's important? Autor Fausther-Bovendo, Hugues, Kobinger, Gary P

“…Pre-existing immunity against human adenovirus (HAd) serotype 5 derived vector in the human population is widespread, thus hampering its clinical use. Various…”
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Nanozyme-strip for rapid local diagnosis of Ebola Autor Duan, Demin, Fan, Kelong, Zhang, Dexi, Tan, Shuguang, Liang, Mifang, Liu, Yang, Zhang, Jianlin, Zhang, Panhe, Liu, Wei, Qiu, Xiangguo, Kobinger, Gary P., Fu Gao, George, Yan, Xiyun

“…Ebola continues to rage in West Africa. In the absence of an approved vaccine or treatment, the priority in controlling this epidemic is to promptly identify…”
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COVID-19: towards controlling of a pandemic Autor Bedford, Juliet, Enria, Delia, Giesecke, Johan, Heymann, David L, Ihekweazu, Chikwe, Kobinger, Gary, Lane, H Clifford, Memish, Ziad, Oh, Myoung-don, Sall, Amadou Alpha, Schuchat, Anne, Ungchusak, Kumnuan, Wieler, Lothar H

“…Most national response strategies include varying levels of contact tracing and self-isolation or quarantine; promotion of public health measures, including…”
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Safety and Immunogenicity of an Anti–Zika Virus DNA Vaccine Autor Tebas, Pablo, Roberts, Christine C, Muthumani, Kar, Reuschel, Emma L, Kudchodkar, Sagar B, Zaidi, Faraz I, White, Scott, Khan, Amir S, Racine, Trina, Choi, Hyeree, Boyer, Jean, Park, Young K, Trottier, Sylvie, Remigio, Celine, Krieger, Diane, Spruill, Susan E, Bagarazzi, Mark, Kobinger, Gary P, Weiner, David B, Maslow, Joel N

“…There are no known specific therapies or vaccines to treat or prevent Zika virus infection. In this report, encouraging data are presented from a phase 1 study…”
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Backs against the wall: novel and existing strategies used during the 2014-2015 Ebola virus outbreak Autor Wong, Gary, Kobinger, Gary P

“…The 2014-2015 outbreak of Ebola virus (EBOV), originating from Guinea, is now responsible for the infection of >20,000 people in 9 countries. Whereas past…”
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Vaccine Candidates against Coronavirus Infections. Where Does COVID-19 Stand? Autor Al-Kassmy, Jawad, Pedersen, Jannie, Kobinger, Gary

“…Seven years after the Middle East respiratory syndrome (MERS) outbreak, a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) made its first…”
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Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp Autor Qiu, Xiangguo, Wong, Gary, Audet, Jonathan, Bello, Alexander, Fernando, Lisa, Alimonti, Judie B., Fausther-Bovendo, Hugues, Wei, Haiyan, Aviles, Jenna, Hiatt, Ernie, Johnson, Ashley, Morton, Josh, Swope, Kelsi, Bohorov, Ognian, Bohorova, Natasha, Goodman, Charles, Kim, Do, Pauly, Michael H., Velasco, Jesus, Pettitt, James, Olinger, Gene G., Whaley, Kevin, Xu, Bianli, Strong, James E., Zeitlin, Larry, Kobinger, Gary P.

“…Without an approved vaccine or treatments, Ebola outbreak management has been limited to palliative care and barrier methods to prevent transmission. These…”
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Mutation Signatures and In Silico Docking of Novel SARS-CoV-2 Variants of Concern Autor Shahhosseini, Nariman, Babuadze, George, Wong, Gary, Kobinger, Gary

“…One year since the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in China, several variants of concern (VOC) have appeared…”
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DNA barcodes corroborating identification of mosquito species and multiplex real-time PCR differentiating Culex pipiens complex and Culex torrentium in Iran Autor Shahhosseini, Nariman, Kayedi, Mohammad Hassan, Sedaghat, Mohammad Mehdi, Racine, Trina, P. Kobinger, Gary, Moosa-Kazemi, Seyed Hassan

“…Identifying mosquito species is a fundamental step in risk assessment and implementation of preventative strategies. Moreover, Culex pipiens is the most…”
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Ebolavirus Evolution: Past and Present Autor de La Vega, Marc-Antoine, Stein, Derek, Kobinger, Gary P

“…The past year has marked the most devastating Ebola outbreak the world has ever witnessed, with over 28,000 cases and over 11,000 deaths. Ebola virus (EBOV)…”
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A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus Autor Gunn, Bronwyn M, Yu, Wen-Han, Karim, Marcus M, Brannan, Jennifer M, Herbert, Andrew S, Wec, Anna Z, Halfmann, Peter J, Fusco, Marnie L, Schendel, Sharon L, Gangavarapu, Karthik, Krause, Tyler, Qiu, Xiangguo, He, Shinhua, Das, Jishnu, Suscovich, Todd J, Lai, Jonathan, Chandran, Kartik, Zeitlin, Larry, Crowe, Jr, James E, Lauffenburger, Douglas, Kawaoka, Yoshihiro, Kobinger, Gary P, Andersen, Kristian G, Dye, John M, Saphire, Erica Ollmann, Alter, Galit

“…The recent Ebola virus (EBOV) epidemic highlighted the need for effective vaccines and therapeutics to limit and prevent outbreaks. Host antibodies against…”
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Structures of protective antibodies reveal sites of vulnerability on Ebola virus Autor Murin, Charles D, Fusco, Marnie L, Bornholdt, Zachary A, Qiu, Xiangguo, Olinger, Gene G, Zeitlin, Larry, Kobinger, Gary P, Ward, Andrew B, Saphire, Erica Ollmann

“…Ebola virus (EBOV) and related filoviruses cause severe hemorrhagic fever, with up to 90% lethality, and no treatments are approved for human use. Multiple…”
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ICTV Virus Taxonomy Profile: Filoviridae Autor Kuhn, Jens H, Amarasinghe, Gaya K, Basler, Christopher F, Bavari, Sina, Bukreyev, Alexander, Chandran, Kartik, Crozier, Ian, Dolnik, Olga, Dye, John M, Formenty, Pierre B H, Griffiths, Anthony, Hewson, Roger, Kobinger, Gary P, Leroy, Eric M, Mühlberger, Elke, Netesov Нетёсов Сергей Викторович, Sergey V, Palacios, Gustavo, Pályi, Bernadett, Pawęska, Janusz T, Smither, Sophie J, Takada 高田礼人, Ayato, Towner, Jonathan S, Wahl, Victoria, Ictv Report Consortium

“…Members of the family Filoviridae produce variously shaped, often filamentous, enveloped virions containing linear non-segmented, negative-sense RNA genomes of…”
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Progression of Ebola Therapeutics During the 2014–2015 Outbreak Autor Mendoza, Emelissa J., Qiu, Xiangguo, Kobinger, Gary P.

“…The recent Ebola virus (EBOV) outbreak in West Africa was the deadliest EBOV epidemic in history, highlighting the need for a safe and efficacious treatment…”
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Ebola-specific therapeutic antibodies from lab to clinic: The example of ZMapp Autor Wong, Gary, Bienes, Kathrina Mae, XIII, Ara, Fausther-Bovendo, Hugues, Kobinger, Gary P.

“…In the 1990s, monoclonal antibodies (mAbs) progressed from scientific tools to advanced therapeutics, particularly for the treatment of cancers and autoimmune…”
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COVID-19 disease—Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and management outcomes in survivors and non-survivors: A longitudinal descriptive cohort study Autor Lanini, Simone, Montaldo, Chiara, Nicastri, Emanuele, Vairo, Francesco, Agrati, Chiara, Petrosillo, Nicola, Scognamiglio, Paola, Antinori, Andrea, Puro, Vincenzo, Di Caro, Antonino, De Carli, Gabriella, Navarra, Assunta, Agresta, Alessandro, Cimaglia, Claudia, Palmieri, Fabrizio, D’Offizi, Gianpiero, Marchioni, Luisa, Kobinger, Gary Pignac, Maeurer, Markus, Girardi, Enrico, Capobianchi, Maria Rosaria, Zumla, Alimuddin, Locatelli, Franco, Ippolito, Giuseppe

“…Detailed temporal analyses of complete (full) blood count (CBC) parameters, their evolution and relationship to patient age, gender, co-morbidities and…”
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Hypercoagulopathy and Adipose Tissue Exacerbated Inflammation May Explain Higher Mortality in COVID-19 Patients With Obesity Autor Pasquarelli-do-Nascimento, Gabriel, Braz-de-Melo, Heloísa Antoniella, Faria, Sara Socorro, Santos, Igor de Oliveira, Kobinger, Gary P., Magalhães, Kelly Grace

“…COVID-19, caused by SARS-CoV-2, is characterized by pneumonia, lymphopenia, exhausted lymphocytes and a cytokine storm. Several reports from around the world…”
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Crimean-Congo Hemorrhagic Fever Virus in Asia, Africa and Europe Autor Shahhosseini, Nariman, Wong, Gary, Babuadze, George, Camp, Jeremy V., Ergonul, Onder, Kobinger, Gary P., Chinikar, Sadegh, Nowotny, Norbert

“…The global spread of ticks and various tick-borne viruses (TBVs) suggests the possibility of new tick-borne diseases emerging. Crimean-Congo hemorrhagic fever…”
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Human Adaptation of Ebola Virus during the West African Outbreak Autor Urbanowicz, Richard A, McClure, C Patrick, Sakuntabhai, Anavaj, Sall, Amadou A, Kobinger, Gary, Müller, Marcel A, Holmes, Edward C, Rey, Félix A, Simon-Loriere, Etienne, Ball, Jonathan K

“…The 2013-2016 outbreak of Ebola virus (EBOV) in West Africa was the largest recorded. It began following the cross-species transmission of EBOV from an animal…”
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