Výsledky vyhľadávania - "Knox, A. J."

Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial Autor Anderson, J. R., Mortimer, K., Pang, L., Smith, K. M, Bailey, H., Hodgson, D. B., Shaw, D. E., Knox, A. J., Harrison, T. W.

“…Peroxisome proliferator-activated receptor gamma (PPAR-γ) is a nuclear receptor that modulates inflammation in models of asthma. To determine whether…”
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Aspirations to grow: When micro- and informal enterprises in the street food sector speak for themselves Autor Knox, A. J, Bressers, Hans Th. A, Mohlakoana, Nthabiseng, De Groot, J

“…The street food sector in Sub-Saharan Africa is a source of affordable and nutritious meals for the urban poor, while also being an important source of income…”
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Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds Autor Morris, G E, Bridge, J C, Eltboli, O M I, Lewis, M P, Knox, A J, Aylott, J W, Brightling, C E, Ghaemmaghami, A M, Rose, F R A J

“…Human airway smooth muscle (HASM) contraction plays a central role in regulating airway resistance in both healthy and asthmatic bronchioles. In vitro studies…”
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CCR3 induced-p42/44 MAPK activation protects against staurosporine induced-DNA fragmentation but not apoptosis in airway smooth muscle cells Autor Markwick, L. J., Clements, D., Roberts, M. E., Ceresa, C. C., Knox, A. J., Johnson, S. R.

“…Summary Background Chemokine receptors (CCRs) are expressed on airway smooth muscle (ASM) cells. As their ligands are present in the airways in asthma, we…”
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Conflict, Carnage, and Cats: Toward a Comic Cú Chulainn in Martin McDonagh's "The Lieutenant of Inishmore" Autor Knox, A. J.

“…There are certain thematic, ideological, and figural connections between Cú Chulainn, the epic hero of the "Táin Bó Cúailnge" of Ireland's mythological Ulster…”
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Reduced expression of cyclooxygenase (COX) in idiopathic pulmonary fibrosis and sarcoidosis Autor Petkova, D K, Clelland, C A, Ronan, J E, Lewis, S, Knox, A J

“…Aims:  To test the hypothesis that cyclooxygenase (COX)‐1 or COX‐2 expression is defective in lungs in idiopathic pulmonary fibrosis (IPF) and to characterize…”
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Population pharmacokinetics of tobramycin administered thrice daily and once daily in children and adults with cystic fibrosis Autor Touw, D.J., Knox, A.J., Smyth, A.

“…Tobramycin pharmacokinetics have not been evaluated previously in a large series of data collected in children and adults with CF receiving once (OD) or three…”
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Impact of Aortic Arch Anatomy on Technical Performance and Clinical Outcomes in Patients with Acute Ischemic Stroke Autor Knox, J A, Alexander, M D, McCoy, D B, Murph, D C, Hinckley, P J, Ch'ang, J C, Dowd, C F, Halbach, V V, Higashida, R T, Amans, M R, Hetts, S W, Cooke, D L

“…Arterial access is a technical consideration of mechanical thrombectomy that may affect procedural time, but few studies exist detailing the relationship of…”
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Dietary antioxidant vitamin intake and lung function in the general population Autor Britton, J R, Pavord, I D, Richards, K A, Knox, A J, Wisniewski, A F, Lewis, S A, Tattersfield, A E, Weiss, S T

“…We have investigated the relation between lung function and dietary intake of the antioxidant vitamins C and E in the general population in a cross-sectional…”
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Overexpression of cyclooxygenase-2 in non-small cell lung cancer Autor Petkova, D.K., Clelland, C., Ronan, J., Pang, L., Coulson, J.M., Lewis, S., Knox, A.J.

“…Evidence is accumulating to suggest that the inducible isoenzyme of cyclooxygenase (COX)-2 is up-regulated in human cancers and epidemiological studies…”
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Functional consequences of AXL sequence variants in hypogonadotropic hypogonadism Autor Salian-Mehta, S, Xu, M, Knox, A J, Plummer, L, Slavov, D, Taylor, M, Bevers, S, Hodges, R S, Crowley, Jr, W F, Wierman, M E

“…Prior studies showed that Axl /Tyro3 null mice have delayed first estrus and abnormal cyclicity due to developmental defects in GnRH neuron migration and…”
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The COX-1/COX-2 balance in asthma Autor PANG, L, PITT, A, PETKOVA, D, KNOX, A. J

“…Prostanoids are important signalling molecules which are produced locally both physiologically and in inflammatory diseases and have potent effects on a number…”
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The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison Autor Prayle, A.P., Jain, K., Touw, D.J., Koch, B.C.P., Knox, A.J., Watson, A., Smyth, A.R.

“…Circadian variation in renal toxicity of aminoglycosides has been demonstrated in animal and human studies. People with CF are frequently prescribed…”
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Mast cell migration to airway smooth muscle in asthma. Can we Gro(w) something to block the attraction? Autor Lagan, A. L., Knox, A. J.

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Pharmacological treatment of the biochemical defect in cystic fibrosis airways Autor Rodgers, H C, Knox, A J

“…The understanding of the biochemical defect in cystic fibrosis (CF) has advanced considerably since discovery of the CF gene in 1989 and characterization of…”
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The TSC-2 product tuberin is expressed in lymphangioleiomyomatosis and angiomyolipoma Autor Johnson, S R, Clelland, C A, Ronan, J, Tattersfield, A E, Knox, A J

“…The TSC‐2 product tuberin is expressed in lymphangioleiomyomatosis and angiomyolipoma Aims: Lymphangioleiomyomatosis is categorized by proliferation of…”
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Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders Autor Kristensen, J.H., Larsen, L., Dasgupta, B., Brodmerkel, C., Curran, M., Karsdal, M.A., Sand, J.M.B., Willumsen, N., Knox, A.J., Bolton, C.E., Johnson, S.R., Hägglund, P., Svensson, B., Leeming, D.J.

“…Elastin is a signature protein of the lungs. Matrix metalloproteinase-7 (MMP-7) is important in lung defence mechanisms and degrades elastin. However, MMP-7…”
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The effect of topical benzamil and amiloride on nasal potential difference in cystic fibrosis Autor Rodgers, H C, Knox, A J

“…The electrochemical defect in the bronchial epithelium in cystic fibrosis (CF) consists of defective chloride secretion and excessive sodium reabsorption. The…”
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Camptothecin-induced apoptosis in non-small cell lung cancer is independent of cyclooxygenase expression Autor Sánchez-Alcázar, J. A., Bradbury, D. A., Brea-Calvo, G., Navas, P., Knox, A. J.

“…Recent observations show a positive correlation between the expression of cyclooxygenase (COX), especially COX-2), and cancer development. Here we tested the…”
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Evaluation of the PPAR-[gamma] agonist pioglitazone in mild asthma: A double-blind randomized controlled trial Autor Anderson, J. R, Mortimer, K, Pang, L, Smith, K. M, Bailey, H, Hodgson, D. B, Shaw, D. E, Knox, A. J, Harrison, T. W

“…Background Peroxisome proliferator-activated receptor gamma (PPAR-[gamma]) is a nuclear receptor that modulates inflammation in models of asthma. To determine…”
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