Suchergebnisse - "Klingström, Jonas"

Anti-Spike Mucosal IgA Protection against SARS-CoV-2 Omicron Infection von Havervall, Sebastian, Marking, Ulrika, Svensson, Julia, Greilert-Norin, Nina, Bacchus, Philip, Nilsson, Peter, Hober, Sophia, Gordon, Max, Blom, Kim, Klingström, Jonas, Åberg, Mikael, Smed-Sörensen, Anna, Thålin, Charlotte

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SARS-CoV-2 variant-specific differences in inhibiting the effects of the PKR-activated integrated stress response von Christ, Wanda, Klingström, Jonas, Tynell, Janne

“… •SARS-CoV-2 triggers the integrated stress response through activation of PKR.•Omicron induces more stress granule formation than Delta or Ancestral …”
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7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection von Marking, Ulrika, Bladh, Oscar, Havervall, Sebastian, Svensson, Julia, Greilert-Norin, Nina, Aguilera, Katherina, Kihlgren, Martha, Salomonsson, Ann-Cristin, Månsson, Maja, Gallini, Radiosa, Kriegholm, Cecilia, Bacchus, Philip, Hober, Sophia, Gordon, Max, Blom, Kim, Smed-Sörensen, Anna, Åberg, Mikael, Klingström, Jonas, Thålin, Charlotte

“… Mucosal immunity has a pivotal role in protection from respiratory viral infections.1 The current authors have showed substantial protection from omicron …”
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Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19 von Sekine, Takuya, Perez-Potti, André, Rivera-Ballesteros, Olga, Strålin, Kristoffer, Gorin, Jean-Baptiste, Olsson, Annika, Llewellyn-Lacey, Sian, Kamal, Habiba, Bogdanovic, Gordana, Muschiol, Sandra, Wullimann, David J, Kammann, Tobias, Emgård, Johanna, Parrot, Tiphaine, Folkesson, Elin, Rooyackers, Olav, Eriksson, Lars I, Henter, Jan-Inge, Sönnerborg, Anders, Allander, Tobias, Albert, Jan, Nielsen, Morten, Klingström, Jonas, Gredmark-Russ, Sara, Björkström, Niklas K, Sandberg, Johan K, Price, David A, Ljunggren, Hans-Gustaf, Aleman, Soo, Buggert, Marcus

“… SARS-CoV-2-specific memory T cells will likely prove critical for long-term immune protection against COVID-19. Here, we systematically mapped the functional …”
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Hantavirus in humans: a review of clinical aspects and management von Vial, Pablo A, Ferrés, Marcela, Vial, Cecilia, Klingström, Jonas, Ahlm, Clas, López, René, Le Corre, Nicole, Mertz, Gregory J

“… Hantavirus infections are part of the broad group of viral haemorrhagic fevers. They are also recognised as a distinct model of an emergent zoonotic infection …”
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Natural killer cell immunotypes related to COVID-19 disease severity von Maucourant, Christopher, Filipovic, Iva, Ponzetta, Andrea, Aleman, Soo, Cornillet, Martin, Hertwig, Laura, Strunz, Benedikt, Lentini, Antonio, Reinius, Björn, Brownlie, Demi, Cuapio, Angelica, Ask, Eivind Heggernes, Hull, Ryan M, Haroun-Izquierdo, Alvaro, Schaffer, Marie, Klingström, Jonas, Folkesson, Elin, Buggert, Marcus, Sandberg, Johan K, Eriksson, Lars I, Rooyackers, Olav, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan, Michaëlsson, Jakob, Marquardt, Nicole, Hammer, Quirin, Strålin, Kristoffer, Björkström, Niklas K

“… Understanding innate immune responses in COVID-19 is important to decipher mechanisms of host responses and interpret disease pathogenesis. Natural killer (NK) …”
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Deaths from Tick-Borne Encephalitis, Sweden von Varnaite, Renata, Gredmark-Russ, Sara, Klingstrom, Jonas

“… We assessed standardized mortality ratio in tick-borne encephalitis (TBE) in Sweden, 2004–2017. Standardized mortality ratio for TBE was 3.96 (95% CI …”
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Heterologous ChAdOx1 nCoV-19 and mRNA-1273 Vaccination von Normark, Johan, Vikström, Linnea, Gwon, Yong-Dae, Persson, Ida-Lisa, Edin, Alicia, Björsell, Tove, Dernstedt, Andy, Christ, Wanda, Tevell, Staffan, Evander, Magnus, Klingström, Jonas, Ahlm, Clas, Forsell, Mattias

“… Health care workers who had received a dose of ChAdOx1 nCoV-19 were offered a choice of receiving either ChAdOx1 nCoV-19 or mRNA-1273 9 to 12 weeks after the …”
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Expansion of SARS-CoV-2-Specific Antibody-Secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients von Varnaitė, Renata, García, Marina, Glans, Hedvig, Maleki, Kimia T, Sandberg, John Tyler, Tynell, Janne, Christ, Wanda, Lagerqvist, Nina, Asgeirsson, Hilmir, Ljunggren, Hans-Gustaf, Ahlén, Gustaf, Frelin, Lars, Sällberg, Matti, Blom, Kim, Klingström, Jonas, Gredmark-Russ, Sara

“… Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in late 2019 and has since become a global …”
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Puumala and Andes Orthohantaviruses Cause Transient Protein Kinase R-Dependent Formation of Stress Granules von Christ, Wanda, Tynell, Janne, Klingström, Jonas

“… Virus infection frequently triggers host cell stress signaling resulting in translational arrest; as a consequence, many viruses employ means to modulate the …”
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Hantavirus inhibits apoptosis by preventing mitochondrial membrane potential loss through up-regulation of the pro-survival factor BCL-2 von Solà-Riera, Carles, García, Marina, Ljunggren, Hans-Gustaf, Klingström, Jonas

“… Hantaviruses, zoonotic RNA viruses belonging to the order Bunyavirales, cause two severe acute diseases in humans, hemorrhagic fever with renal syndrome (HFRS) …”
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Evaluation of 11 SARS-CoV-2 antibody tests by using samples from patients with defined IgG antibody titers von Lagerqvist, Nina, Maleki, Kimia T., Verner-Carlsson, Jenny, Olausson, Mikaela, Dillner, Joakim, Wigren Byström, Julia, Monsen, Tor, Forsell, Mattias, Eriksson, Jenny, Bogdanovic, Gordana, Muschiol, Sandra, Ljunggren, Joel, Repo, Johanna, Kjerstadius, Torbjörn, Muradrasoli, Shaman, Brytting, Mia, Szekely Björndal, Åsa, Åkerlund, Thomas, Nilsson, Charlotta, Klingström, Jonas

“… We evaluated the performance of 11 SARS-CoV-2 antibody tests using a reference set of heat-inactivated samples from 278 unexposed persons and 258 COVID-19 …”
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Orthohantaviruses belonging to three phylogroups all inhibit apoptosis in infected target cells von Solà-Riera, Carles, Gupta, Shawon, Ljunggren, Hans-Gustaf, Klingström, Jonas

“… Orthohantaviruses, previously known as hantaviruses, are zoonotic viruses that can cause hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal …”
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SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection von Havervall, Sebastian, Jernbom Falk, August, Klingström, Jonas, Ng, Henry, Greilert-Norin, Nina, Gabrielsson, Lena, Salomonsson, Ann-Christin, Isaksson, Eva, Rudberg, Ann-Sofie, Hellström, Cecilia, Andersson, Eni, Olofsson, Jennie, Skoglund, Lovisa, Yousef, Jamil, Pin, Elisa, Christ, Wanda, Olausson, Mikaela, Hedhammar, My, Tegel, Hanna, Mangsbo, Sara, Phillipson, Mia, Månberg, Anna, Hober, Sophia, Nilsson, Peter, Thålin, Charlotte

“… Current SARS-CoV-2 serological assays generate discrepant results, and the longitudinal characteristics of antibodies targeting various antigens after …”
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SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells von Hammer, Quirin, Dunst, Josefine, Christ, Wanda, Picarazzi, Francesca, Wendorff, Mareike, Momayyezi, Pouria, Huhn, Oisín, Netskar, Herman K., Maleki, Kimia T., García, Marina, Sekine, Takuya, Sohlberg, Ebba, Azzimato, Valerio, Aouadi, Myriam, Degenhardt, Frauke, Franke, Andre, Spallotta, Francesco, Mori, Mattia, Michaëlsson, Jakob, Björkström, Niklas K., Rückert, Timo, Romagnani, Chiara, Horowitz, Amir, Klingström, Jonas, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan

“… Natural killer (NK) cells are innate immune cells that contribute to host defense against virus infections. NK cells respond to severe acute respiratory …”
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Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity von Kvedaraite, Egle, Hertwig, Laura, Sinha, Indranil, Ponzetta, Andrea, Hed Myrberg, Ida, Lourda, Magda, Dzidic, Majda, Akber, Mira, Klingström, Jonas, Folkesson, Elin, Muvva, Jagadeeswara Rao, Chen, Puran, Gredmark-Russ, Sara, Brighenti, Susanna, Norrby-Teglund, Anna, Eriksson, Lars I, Rooyackers, Olav, Aleman, Soo, Strålin, Kristoffer, Ljunggren, Hans-Gustaf, Ginhoux, Florent, Björkström, Niklas K, Henter, Jan-Inge, Svensson, Mattias

“… Dendritic cells (DCs) and monocytes are crucial mediators of innate and adaptive immune responses during viral infection, but misdirected responses by these …”
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NK cells are activated and primed for skin-homing during acute dengue virus infection in humans von Zimmer, Christine L., Cornillet, Martin, Solà-Riera, Carles, Cheung, Ka-Wai, Ivarsson, Martin A., Lim, Mei Qiu, Marquardt, Nicole, Leo, Yee-Sin, Lye, David Chien, Klingström, Jonas, MacAry, Paul A., Ljunggren, Hans-Gustaf, Rivino, Laura, Björkström, Niklas K.

“… Despite animal models showing that natural killer (NK) cells are important players in the early defense against many viral infections, the NK cell response is …”
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Broad anti-SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination von Kaku, Chengzi I, Champney, Elizabeth R, Normark, Johan, Garcia, Marina, Johnson, Carl E, Ahlm, Clas, Christ, Wanda, Sakharkar, Mrunal, Ackerman, Margaret E, Klingström, Jonas, Forsell, Mattias N E, Walker, Laura M

“… Heterologous prime-boost immunization strategies have the potential to augment COVID-19 vaccine efficacy. We longitudinally profiled severe acute respiratory …”
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Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia von Palma Medina, Laura M., Babačić, Haris, Dzidic, Majda, Parke, Åsa, Garcia, Marina, Maleki, Kimia T., Unge, Christian, Lourda, Magda, Kvedaraite, Egle, Chen, Puran, Muvva, Jagadeeswara Rao, Cornillet, Martin, Emgård, Johanna, Moll, Kirsten, Michaëlsson, Jakob, Flodström-Tullberg, Malin, Brighenti, Susanna, Buggert, Marcus, Mjösberg, Jenny, Malmberg, Karl-Johan, Sandberg, Johan K., Gredmark-Russ, Sara, Rooyackers, Olav, Svensson, Mattias, Chambers, Benedict J., Eriksson, Lars I., Pernemalm, Maria, Björkström, Niklas K., Aleman, Soo, Ljunggren, Hans-Gustaf, Klingström, Jonas, Strålin, Kristoffer, Norrby-Teglund, Anna

“… Background COVID-19 remains a major public health challenge, requiring the development of tools to improve diagnosis and inform therapeutic decisions. As …”
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Clinical grade ACE2 as a universal agent to block SARS‐CoV‐2 variants von Monteil, Vanessa, Eaton, Brett, Postnikova, Elena, Murphy, Michael, Braunsfeld, Benedict, Crozier, Ian, Kricek, Franz, Niederhöfer, Janine, Schwarzböck, Alice, Breid, Helene, Devignot, Stephanie, Klingström, Jonas, Thålin, Charlotte, Kellner, Max J, Christ, Wanda, Havervall, Sebastian, Mereiter, Stefan, Knapp, Sylvia, Sanchez Jimenez, Anna, Bugajska‐Schretter, Agnes, Dohnal, Alexander, Ruf, Christine, Gugenberger, Romana, Hagelkruys, Astrid, Montserrat, Nuria, Kozieradzki, Ivona, Hasan Ali, Omar, Stadlmann, Johannes, Holbrook, Michael R, Schmaljohn, Connie, Oostenbrink, Chris, Shoemaker, Robert H, Mirazimi, Ali, Wirnsberger, Gerald, Penninger, Josef M

“… The recent emergence of multiple SARS‐CoV‐2 variants has caused considerable concern due to both reduced vaccine efficacy and escape from neutralizing antibody …”
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