Suchergebnisse - "Klassen, Giseli"

Chemical characterization and antineoplastic effect of oligosaccharides from Cabernet Franc red wine in mammary tumor model in mice von Oliveira, Natalia Mulinari Turin, dos Santos, André Eduardo, Corso, Claudia Rita, Galindo, Claudia Martins, Adami, Eliana Rezende, da Silva, Liziane Cristine Malaquias, de Lima, Lucas Trevisan França, de Santana Filho, Arquimedes Paixão, Dittrich, Rosangela Locatelli, Klassen, Giseli, de Souza Ramos, Edneia Amancio, Sassaki, Guilherme Lanzi, Acco, Alexandra

“… The present study characterized oligosaccharide compounds (Oligo) in Cabernet Franc red wine and investigated its antineoplastic effects against mammary tumor …”
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4-Nitrochalcone as a potential drug in non-clinical breast cancer studies von Galindo, Claudia Martins, Milani, Letícia, de Lima, Lucas Trevisan França, Adami, Eliana Rezende, Go, Simei, de Noronha, Lucia, Beltrame, Olair Carlos, Klassen, Giseli, de Souza Ramos, Edneia Amancio, Elferink, Ronald P.J. Oude, Acco, Alexandra

“… Breast cancer is a high-magnitude public health problem, continually challenging physicians and scientists worldwide in the field of drug therapy …”
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Mixed-Valence Pentadecavanadate with Ca2+-ATPase Inhibition Potential and Anti-Breast Cancer Activity von Brito, Bianca R., Camilo, Heloísa de S., Cruz, Anderson F. da, Ribeiro, Ronny R., de Sá, Eduardo L., Camargo de Oliveira, Carolina, Fraqueza, Gil, Klassen, Giseli, Aureliano, Manuel, Nunes, Giovana G.

“… Polyoxovanadates are a subclass of polyoxometalates (POMs) known to interact with proteins and to present anticancer, antimicrobial, and antiviral activities …”
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Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms von Corso, Claudia Rita, Stipp, Maria Carolina, Radulski, Débora Rasec, Mariott, Marihá, da Silva, Luisa Mota, de Souza Ramos, Edneia Amancio, Klassen, Giseli, Queiroz Telles, José Ederaldo, Oliveira, Cristhian Santos, Stefanello, Maria Élida Alves, Verhoeven, Arthur J., Oude Elferink, Ronald P. J., Acco, Alexandra

“… Natural products have been recognized as important bioactive compounds on the basis of their wide biological properties. Here we investigated the antitumor …”
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Morphological, genotypic, and physiological characterization of Acanthamoeba isolates from keratitis patients and the domestic environment in Vitoria, Espírito Santo, Brazil von Duarte, Juliana L., Furst, Cinthia, Klisiowicz, Débora R., Klassen, Giseli, Costa, Adriana O.

“… •Acanthamoeba samples from Vitória, Brazil genotyped as T4 and T11 tolerated 37°C.•One keratitis isolate cultivated in NNA with E. coli survived at 42°C.•All …”
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Epigenetic Changes of CXCR4 and Its Ligand CXCL12 as Prognostic Factors for Sporadic Breast Cancer von Ramos, Edneia A. S., Grochoski, Mariana, Braun-Prado, Karin, Seniski, Gerusa G., Cavalli, Iglenir J., Ribeiro, Enilze M. S. F., Camargo, Anamaria A., Costa, Fabrício F., Klassen, Giseli

“… Chemokines and their receptors are involved in the development and cancer progression. The chemokine CXCL12 interacts with its receptor, CXCR4, to promote …”
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Salvia lachnostachys Benth has antitumor and chemopreventive effects against solid Ehrlich carcinoma von Corso, Claudia Rita, Stipp, Maria Carolina, Adami, Eliana Rezende, da Silva, Luisa Mota, Mariott, Marihá, de Andrade, Sergio Faloni, de Souza Ramos, Edneia Amancio, Klassen, Giseli, Beltrame, Olair Carlos, Queiroz-Telles, José Ederaldo, de Oliveira, Cristhian Santos, Stefanello, Maria Élida Alves, Acco, Alexandra

“… Salvia lachnostachys is an herbaceous plant with anti-inflammatory, analgesic and cytotoxic properties. This study investigated the antitumor effect of an …”
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Fibronectin Affects Transient MMP2 Gene Expression through DNA Demethylation Changes in Non-Invasive Breast Cancer Cell Lines von Pereira, Isabela T., Ramos, Edneia A. S., Costa, Erico T., Camargo, Anamaria A., Manica, Graciele C. M., Klassen, Liliane M. B., Chequin, Andressa, Braun-Prado, Karin, de O. Pedrosa, Fábio, Souza, Emanuel M., Costa, Fabricio F., Klassen, Giseli

“… Metastasis accounts for more than 90% of cancer deaths. Cells from primary solid tumors may invade adjacent tissues and migrate to distant sites where they …”
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Simultaneous CXCL12 and ESR1 CpG island hypermethylation correlates with poor prognosis in sporadic breast cancer von Ramos, Edneia AS, Camargo, Anamaria A, Braun, Karin, Slowik, Renata, Cavalli, Iglenir J, Ribeiro, Enilze MSF, Pedrosa, Fábio de O, de Souza, Emanuel M, Costa, Fabrício F, Klassen, Giseli

“… Background CXCL12 is a chemokine that is constitutively expressed in many organs and tissues. CXCL12 promoter hypermethylation has been detected in primary …”
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ADAM33 gene silencing by promoter hypermethylation as a molecular marker in breast invasive lobular carcinoma von Seniski, Gerusa G, Camargo, Anamaria A, Ierardi, Daniela F, Ramos, Edneia AS, Grochoski, Mariana, Ribeiro, Enilze SF, Cavalli, Iglenir J, Pedrosa, Fabio O, de Souza, Emanuel M, Zanata, Silvio M, Costa, Fabrício F, Klassen, Giseli

“… Background ADAM33 protein is a member of the family of transmembrane glycoproteins composed of multidomains. ADAM family members have different activities, …”
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Tissue distribution of quiescin Q6/sulfhydryl oxidase (QSOX) in developing mouse von Portes, Kelly F., Ikegami, Cecília M., Getz, Joselito, Martins, Ana P., de Noronha, Lucia, Zischler, Luciana F., Klassen, Giseli, Camargo, Anamaria A., Zanata, Silvio M., Bevilacqua, Estela, Nakao, Lia S.

“… Quiescin Q6/sulfhydryl oxidases (QSOX) are revisited thiol oxidases considered to be involved in the oxidative protein folding, cell cycle control and …”
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Biochemical properties, enterohaemolysin production and plasmid carriage of Shiga toxin-producing Escherichia coli strains von Souza, Mario R.S.R.S.M, Klassen, Giseli, De Toni, Fabiana, Rigo, Liu U, Henkes, Caroline, Pigatto, Caroline P, Dalagassa, Cibelle de Borba, Fadel-Picheth, Cyntia M.T

“… Thirty-eight strains of Shiga toxin-producing Escherichia coli (STEC) were characterised in terms of biochemical properties, enterohaemolysin production and …”
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Nitrogenase switch-off by ammonium ions in Azospirillum brasilense requires the GlnB nitrogen signal-transducing protein von Klassen, Giseli, Souza, Emanuel M, Yates, M Geoffrey, Rigo, Liu Un, Costa, Roberta M, Inaba, Juliana, Pedrosa, Fábio O

“… Nitrogenase activity in several diazotrophs is switched off by ammonium and reactivated after consumption. The signaling pathway to this system in Azospirillum …”
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All-polysaccharide, self-healing, pH-sensitive, in situ-forming hydrogel of carboxymethyl chitosan and aldehyde-functionalized hydroxyethyl cellulose von Quadrado, Rafael F.N., Zhai, Zhenghao, Zavadinack, Matheus, Klassen, Giseli, Iacomini, Marcello, Edgar, Kevin J., Fajardo, André R.

“… In situ forming hydrogels are promising for biomedical applications, especially in drug delivery. The precursor solution can be injected at the target site, …”
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The Involvement of the nif-Associated Ferredoxin-Like Genes fdxA and fdxN of Herbaspirillum seropedicae in Nitrogen Fixation von Souza, Andre L.F., Universidade Federal do Parana, CP, Brazil, Invitti, Adriana L., Universidade Federal do Parana, CP, Brazil, Rego, Fabiane G.M., Universidade Federal do Parana, CP, Brazil, Monteiro, Rose A., Universidade Federal do Parana, CP, Brazil, Klassen, Giseli, Universidade Federal do Parana, CP, Brazil, Souza, Emanuel M., Universidade Federal do Parana, CP, Brazil, Chubatsu, Leda S., Universidade Federal do Parana, CP, Brazil, Pedrosa, Fabio O., Universidade Federal do Parana, CP, Brazil, Rigo, Liu U., Universidade Federal do Parana, CP, Brazil

“… The pathway of electron transport to nitrogenase in the endophytic β-Proteobacterium Herbaspirillum seropedicae has not been characterized. We have generated …”
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Structural characterization and anticancer properties of a novel mushroom-derived rhamnogalactan in a triple-negative breast cancer model von de Lara, Eliane Leal, Zavadinack, Matheus, da Silva Milhorini, Shayane, Wurzer, Karin Maciel, Klassen, Giseli, Cordeiro, Lucimara M.C., Iacomini, Marcello

“… Mushroom-derived polysaccharides are known for their diverse biological activities, including immunomodulatory and anticancer properties. Breast cancer, the …”
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Control of nitrogenase reactivation by the GlnZ protein in Azospirillum brasilense von Klassen, G, de Souza, E M, Yates, M G, Rigo, L U, Inaba, J, Pedrosa, F de O

“… The glnZ mutant of Azospirillum brasilense (strain 7611) showed only partial recovery (20 to 40%) after 80 min of ammonia-induced nitrogenase switch-off, …”
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Nuances of PFKFB3 Signaling in Breast Cancer von Galindo, Claudia Martins, Oliveira Ganzella, Fernando Augusto de, Klassen, Giseli, Souza Ramos, Edneia Amancio de, Acco, Alexandra

“… •Cellular metabolism, survival, and proliferation are linked with PFKFB3 activity.•Hormonal status drives PFKFB3 activity in breast cancer.•PFKFB3 links …”
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l-carvone decreases breast cancer cells adhesion, migration, and invasion by suppressing FAK activation von Lima, Lucas Trevisan França de, Ganzella, Fernando Augusto de Oliveira, Cardoso, Gabriela Casani, Pires, Verônica dos Santos, Chequin, Andressa, Santos, Giulia Luiza, Braun-Prado, Karin, Galindo, Claudia Martins, Braz Junior, Odair, Molento, Marcelo Beltrão, Acco, Alexandra, Adami, Eliana Rezende, Costa, Erico Tosoni, Cavichiolo Franco, Célia Regina, Klassen, Giseli, Ramos, Edneia Amancio de Souza

“… Breast cancer is one of the most common types of cancer in the world and current therapeutic strategies present severe drawbacks. l-carvone (CRV), a …”
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Antitumoral activity of liraglutide, a new DNMT inhibitor in breast cancer cells in vitro and in vivo von Chequin, Andressa, Costa, Luiz E., de Campos, Felipe F., Moncada, Angie D.B., de Lima, Lucas T.F., Sledz, Lucas R., Picheth, Guilherme F., Adami, Eliana R., Acco, Alexandra, Gonçalves, Marcos B., Manica, Graciele C.M., Valdameri, Gláucio, de Noronha, Lucia, Telles, José E.Q., Jandrey, Elisa H.F., Costa, Erico T., Costa, Fabricio F., de Souza, Emanuel M., Ramos, Edneia A.S., Klassen, Giseli

“… Breast cancer (BC) is the most frequently diagnosed female cancer and second leading cause of death. Despite the discovery of many antineoplastic drugs for BC, …”
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