Suchergebnisse - "Kitchen, Steve"

Anti‐PF4 testing for vaccine‐induced immune thrombocytopenia and thrombosis and heparin induced thrombocytopenia: Results from a UK National External Quality Assessment Scheme exercise April 2021 von Reilly‐Stitt, Christopher, Kitchen, Steve, Jennings, Ian, Horner, Kevin, Jones, Robert, Makris, Mike, Walker, Isobel D.

“… Background Vaccine‐induced immune thrombocytopenia and thrombosis (VITT) following the administration of the AstraZeneca (AZ) ChAdOx1 nCOV‐19 vaccine has …”
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A global comparative field study to evaluate the factor VIII activity of efanesoctocog alfa by one‐stage clotting and chromogenic substrate assays at clinical haemostasis laboratories von Pipe, Steven, Sadeghi‐Khomami, Ali, Konkle, Barbara A., Kitchen, Steve, Negrier, Claude, Liu, Mingjie, Santagostino, Elena, Willemze, Annemieke, Abad‐Franch, Lydia, Knobe, Karin, Seth Chhabra, Ekta

“… Introduction Structural and chemical modifications of factor VIII (FVIII) products may influence their behaviour in FVIII activity assays. Hence, it is …”
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Dabigatran effects on the international normalized ratio, activated partial thromboplastin time, thrombin time, and fibrinogen: a multicenter, in vitro study von Dager, William E, Gosselin, Robert C, Kitchen, Steve, Dwyre, Dennis

“… Patients receiving the direct thrombin inhibitor dabigatran may have selected anticoagulation assays performed as part of routine care. The effect of …”
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The Effect of Dabigatran on Select Specialty Coagulation Assays von Adcock, Dorothy M., Gosselin, Robert, Kitchen, Steve, Dwyre, Denis M.

“… Dabigatran etexilate is a new oral anticoagulant that functions as a direct thrombin inhibitor. An inhibitor of thrombin has the potential to interfere with …”
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Haemolysis: an overview of the leading cause of unsuitable specimens in clinical laboratories von Lippi, Giuseppe, Blanckaert, Norbert, Bonini, Pierangelo, Green, Sol, Kitchen, Steve, Palicka, Vladimir, Vassault, Anne J, Plebani, Mario

“… Prevention of medical errors is a major goal of healthcare, though healthcare workers themselves have not yet fully accepted or implemented reliable models of …”
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Effects of Emicizumab on APTT, FVIII assays and FVIII Inhibitor assays using different reagents: Results of a UK NEQAS proficiency testing exercise von Lowe, Anna, Kitchen, Steve, Jennings, Ian, Kitchen, Dianne P., Woods, Tim A. L., Walker, Isobel D.

“… Introduction Emicizumab (Hemlibra: Roche Switzerland) is a, humanized, bi‐specific monoclonal modified immunoglobulin G4 (IgG4) which binds human FX, FIX and …”
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Specific and global coagulation assays in the diagnosis of discrepant mild hemophilia A von Bowyer, A. E., Van Veen, J. J., Goodeve, A. C., Kitchen, S., Makris, M.

“… The activity of the factor VIII coagulation protein can be measured by three methods: a one or two-stage clotting assay and a chromogenic assay. The factor …”
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Caution in Using the Activated Partial Thromboplastin Time to Monitor Argatroban in COVID-19 and Vaccine-Induced Immune Thrombocytopenia and Thrombosis (VITT) von Guy, Susan, Kitchen, Steve, Makris, Michael, M. Maclean, Rhona, Saccullo, Giorgia, Vanveen, Joost J

“… Introduction Argatroban is licensed for patients with heparin-induced thrombocytopenia and is conventionally monitored by activated partial thromboplastin time …”
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Improving access to hemophilia care in sub-Saharan Africa by capacity building von Diop, Saliou, Haffar, Assad, Mahlangu, Johnny, Chami, Irene, Kitchen, Steve, Pierce, Glenn

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Quality in Laboratory Hemostasis and Thrombosis von Kitchen, Steve, Olson, John D, Preston, F. Eric, Rosendaal, Frits R

“… "Over the last decades, major progress has been made in quality assurance of hemostatic laboratory assays. This book will be an indispensable part of every …”
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Thrombin generation assays are superior to traditional tests in assessing anticoagulation reversal in vitro von Gatt, Alex, van Veen, Joost J, Woolley, Anita M, Kitchen, Steve, Cooper, Peter, Makris, Michael

“… Even though new anticoagulants are being devised with the notion that they do not require regular monitoring, when bleeding occurs, it is important to have an …”
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Quality in Laboratory Hemostasis and Thrombosis von Kitchen, Steve, Olson, John D, Preston, F. Eric

“… The hemostasis laboratory has a vital role in the diagnosis and management of patients with familial and acquired hemorrhagic and thrombotic disorders. Rapid …”
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The natural history of glycogen storage disease type Ib in England: A multisite survey von Halligan, Rebecca, White, Fiona J., Schwahn, Bernd, Stepien, Karolina M., Kamarus Jaman, Nazreen, McSweeney, Mel, Kitchen, Steve, Gribben, Joanna, Dawson, Charlotte, Lewis, Katherine, Cregeen, David, Mundy, Helen, Santra, Saikat

“… Glycogen storage disease type Ib (GSDIb) is characterized by hepatomegaly and fasting hypoglycaemia as well as neutropaenia and recurrent infections. We …”
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Development of national consensus statements on food labelling interpretation and protein allocation in a low phenylalanine diet for PKU von Evans, Sharon, Ford, Suzanne, Adam, Sarah, Adams, Sandra, Ash, Jane, Ashmore, Catherine, Caine, Gillian, Carruthers, Rachel, Cawtherley, Sarah, Chahal, Satnam, Clark, Anne, Cochrane, Barbara, Daly, Anne, Dines, Karen, Dixon, Marjorie, Dunlop, Carolyn, Ellerton, Charlotte, French, Moira, Gaff, Lisa, Gingell, Cerys, Green, Diane, Gribben, Joanna, Grimsley, Anne, Hallam, Paula, Hendroff, Una, Hill, Melanie, Hoban, Rachel, Howe, Sarah, Hunjan, Inderdip, Kaalund, Kit, Kelleher, Eimear, Khan, Farzana, Kitchen, Steve, Lang, Karen, Lowry, Sharan, Males, Jo, Martin, Georgina, McStravick, Nicola, Micciche, Avril, Newby, Camille, Nicol, Claire, Pereira, Rachel, Robertson, Louise, Ross, Kathleen, Simpson, Emma, Singleton, Kath, Skeath, Rachel, Stafford, Jacqueline, Terry, Allyson, Thom, Ruth, Tooke, Alison, vanWyk, Karen, White, Fiona, White, Lucy, MacDonald, Anita

“… Background In the treatment of phenylketonuria (PKU), there was disparity between UK dietitians regarding interpretation of how different foods should be …”
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Monitoring ultralong half-life recombinant factor VIII: a product-specific calibrator is urgently needed to enable accurate measurement in all patients von Bowyer, Annette, Kitchen, Steve

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Evaluation of Clauss Fibrinogen Assay Clot Waveform Analysis for the Detection of Dysfibrinogenemia on Sysmex CN‐6000 von Horner, Kevin, Kitchen, Steve

“… Dysfibrinogenemia is associated with thrombosis and bleeding. Identification is important as it correlates with adverse clinical outcomes. Clot waveform …”
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Emergency oral anticoagulant reversal: the relative efficacy of infusions of fresh frozen plasma and clotting factor concentrate on correction of the coagulopathy von Makris, M, Greaves, M, Phillips, W S, Kitchen, S, Rosendaal, F R, Preston, E F

“… Haemorrhage, including intracranial bleeding, is a common, potentially lethal complication of warfarin therapy and rapid and complete reversal of …”
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Laboratory D-dimer measurement: improved agreement between methods through calibration von Jennings, Ian, Woods, Timothy A L, Kitchen, Dianne P, Kitchen, Steve, Walker, Isobel D

“… Accurate and precise measurement of plasma D-dimer levels is important in the diagnosis and management of venous thromboembolism. Considerable variability in …”
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Factor Activity Assays for Monitoring Extended Half-Life FVIII and Factor IX Replacement Therapies von Kitchen, Steve, Tiefenbacher, Stefan, Gosselin, Robert

“… The advent of modified factor VIII (FVIII) and factor IX (FIX) molecules with extended half-lives (EHLs) compared with native FVIII and FIX represents a major …”
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The effect of a next generation factor VIII mimetic bispecific antibody (Mim8) on assays of factor VIII activity and thrombin generation von Bowyer, Annette Elizabeth, Kitchen, Steve, Ezban, Mirella

“… Mim8 is a next generation bispecific antibody developed for the prophylactic treatment of hemophilia A. The sensitivity of activated plasma thromboplastin time …”
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