Suchergebnisse - "Kenyon, Amy"

Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair von Simões, Filipa C., Cahill, Thomas J., Kenyon, Amy, Gavriouchkina, Daria, Vieira, Joaquim M., Sun, Xin, Pezzolla, Daniela, Ravaud, Christophe, Masmanian, Eva, Weinberger, Michael, Mayes, Sarah, Lemieux, Madeleine E., Barnette, Damien N., Gunadasa-Rohling, Mala, Williams, Ruth M., Greaves, David R., Trinh, Le A., Fraser, Scott E., Dallas, Sarah L., Choudhury, Robin P., Sauka-Spengler, Tatjana, Riley, Paul R.

“… Canonical roles for macrophages in mediating the fibrotic response after a heart attack include extracellular matrix turnover and activation of cardiac …”
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In Defense of Numbers von Kenyon, Amy L.

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Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma von Falletta, Paola, Sanchez-Del-Campo, Luis, Chauhan, Jagat, Effern, Maike, Kenyon, Amy, Kershaw, Christopher J, Siddaway, Robert, Lisle, Richard, Freter, Rasmus, Daniels, Matthew J, Lu, Xin, Tüting, Thomas, Middleton, Mark, Buffa, Francesca M, Willis, Anne E, Pavitt, Graham, Ronai, Ze'ev A, Sauka-Spengler, Tatjana, Hölzel, Michael, Goding, Colin R

“… The intratumor microenvironment generates phenotypically distinct but interconvertible malignant cell subpopulations that fuel metastatic spread and …”
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RFX transcription factors control a miR-150/PDAP1 axis that restrains the proliferation of human T cells von Chirichella, Michele, Bianchi, Niccolò, Džafo, Emina, Foli, Elena, Gualdrini, Francesco, Kenyon, Amy, Natoli, Gioacchino, Monticelli, Silvia

“… Within the immune system, microRNAs (miRNAs) exert key regulatory functions. However, what are the mRNA targets regulated by miRNAs and how miRNAs are …”
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Active nuclear transcriptome analysis reveals inflammasome-dependent mechanism for early neutrophil response to Mycobacterium marinum von Kenyon, Amy, Gavriouchkina, Daria, Zorman, Jernej, Napolitani, Giorgio, Cerundolo, Vincenzo, Sauka-Spengler, Tatjana

“… The mechanisms governing neutrophil response to Mycobacterium tuberculosis remain poorly understood. In this study we utilise biotagging, a novel genome-wide …”
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Hsp90 Binds Directly to Fibronectin (FN) and Inhibition Reduces the Extracellular Fibronectin Matrix in Breast Cancer Cells von Hunter, Morgan C., O’Hagan, Kyle L., Kenyon, Amy, Dhanani, Karim C. H., Prinsloo, Earl, Edkins, Adrienne L.

“… Heat shock protein 90 (Hsp90) has been identified in the extracellular space and has been shown to chaperone a finite number of extracellular proteins involved …”
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Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain von Andrews, Mark D., af Forselles, Kerry, Beaumont, Kevin, Galan, Sebastien R. G., Glossop, Paul A., Grenie, Mathilde, Jessiman, Alan, Kenyon, Amy S., Lunn, Graham, Maw, Graham, Owen, Robert M., Pryde, David C., Roberts, Dannielle, Thien Duc Tran

“… The transient receptor potential (TRP) family of ion channels comprises nonselective cation channels that respond to a wide range of chemical and thermal …”
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Generation of a double binary transgenic zebrafish model to study myeloid gene regulation in response to oncogene activation in melanocytes von Kenyon, Amy, Gavriouchkina, Daria, Zorman, Jernej, Chong-Morrison, Vanessa, Napolitani, Giorgio, Cerundolo, Vincenzo, Sauka-Spengler, Tatjana

“… A complex network of inflammation succeeds somatic cell transformation and malignant disease. Immune cells and their associated molecules are responsible for …”
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A Real Time Chemotaxis Assay Unveils Unique Migratory Profiles amongst Different Primary Murine Macrophages von Iqbal, Asif J., Regan-Komito, Daniel, Christou, Ivy, White, Gemma E., McNeill, Eileen, Kenyon, Amy, Taylor, Lewis, Kapellos, Theodore S., Fisher, Edward A., Channon, Keith M., Greaves, David R.

“… Chemotaxis assays are an invaluable tool for studying the biological activity of inflammatory mediators such as CC chemokines, which have been implicated in a …”
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Molecular hybridization yields triazole bronchodilators for the treatment of COPD von Jones, Lyn H., Burrows, Jane, Feeder, Neil, Glossop, Paul, James, Kim, Jones, Rhys M., Kenyon, Amy S., Patel, Sheena, Roberts, Dannielle F., Selby, Matthew D., Strang, Ross S., Stuart, Emilio F., Trevethick, Michael A., Watson, Jessica, Wright, Karen N., Clarke, Nick

“… [Display omitted] A 1,2,4-triazole motif was employed as a bioisostere for the ester commonly used in muscarinic antagonists, and subsequent integrative …”
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Dreaming suburbia : Detroit and the production of postwar space and culture von Kenyon, Amy Maria

“… A multifaceted cultural study of suburbanization in the United States, and Detroit in particular, during the postwar suburban boom. Dreaming Suburbia is a …”
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Inhalation by design: Dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD von Jones, Lyn H., Baldock, Helen, Bunnage, Mark E., Burrows, Jane, Clarke, Nick, Coghlan, Michele, Entwistle, David, Fairman, David, Feeder, Neil, Fulton, Craig, Hilton, Laura, James, Kim, Jones, Rhys M., Kenyon, Amy S., Marshall, Stuart, Newman, Sandra D., Osborne, Rachel, Patel, Sheena, Selby, Matthew D., Stuart, Emilio F., Trevethick, Michael A., Wright, Karen N., Price, David A.

“… This paper describes the successful design and development of dual pharmacology β-2 agonists-M3 antagonists, for the treatment of chronic obstructive pulmonary …”
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Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease von Mishra, Neha, Aden, Konrad, Blase, Johanna I., Baran, Nathan, Bordoni, Dora, Tran, Florian, Conrad, Claudio, Avalos, Diana, Jaeckel, Charlot, Scherer, Michael, Sørensen, Signe B., Overgaard, Silja H., Schulte, Berenice, Nikolaus, Susanna, Rey, Guillaume, Gasparoni, Gilles, Lyons, Paul A., Schultze, Joachim L., Walter, Jörn, Andersen, Vibeke, Dermitzakis, Emmanouil T., Schreiber, Stefan, Rosenstiel, Philip

“… Background and aims Treatment with tumor necrosis factor α (TNFα) antagonists in IBD patients suffers from primary non-response rates of up to 40%. Biomarkers …”
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Efficient Conversion of a Nonselective Norepinephrin Reuptake Inhibitor into a Dual Muscarinic Antagonist beta(2)-Agonist for the Treatment of Chronic Obstructive Pulmonary Disease von Osborne, Rachel, Clarke, Nick, Glossop, Paul, Kenyon, Amy, Liu, Hao, Patel, Sheena, Summerhill, Susan, Jones, Lyn H.

“… Following interrogation of a wide-ligand profile database, a nonselective norepinephrin reuptake inhibitor was converted into a novel muscarinic antagonist …”
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Hsp90 Binds Directly to Fibronectin von Hunter, Morgan C, O'Hagan, Kyle L, Kenyon, Amy, Dhanani, Karim C. H, Prinsloo, Earl, Edkins, Adrienne L

“… Heat shock protein 90 (Hsp90) has been identified in the extracellular space and has been shown to chaperone a finite number of extracellular proteins involved …”
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The promise of zebrafish: a novel resource to study the myeloid response in vivo von Kenyon, Amy

“… Oncogenic transformation, local tissue damage at a site of injury, or invading pathogens all induce signals resulting in the recruitment of macrophages and …”
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Efficient conversion of a nonselective norepinephrin reuptake inhibitor into a dual muscarinic antagonist-β₂-agonist for the treatment of chronic obstructive pulmonary disease von Osborne, Rachel, Clarke, Nick, Glossop, Paul, Kenyon, Amy, Liu, Hao, Patel, Sheena, Summerhill, Susan, Jones, Lyn H

“… Following interrogation of a wide-ligand profile database, a nonselective norepinephrin reuptake inhibitor was converted into a novel muscarinic antagonist …”
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KENYON: Universities should consider real cost of internships von Kenyon, Amy

“… While this learning experience is wonderfully important, it also takes up a good deal of time. Because of the pressures involved with student teaching, we are …”
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Point/counterpoint: Education reform shouldn't be based on numbers von Kenyon, Amy

“… Suggesting that increased charter and private schools will encourage public schools to step up ignores how public schools have had their hands tied by …”
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KENYON: Social activism achievable through involvement, knowledge von Kenyon, Amy

“… Publication: Daily Nebraskan, University of Nebraska-Lincoln, Lincoln NE. his summer, I spent a week in Washington D.C. listening to speakers who represented …”
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